FI972793A - Nebivololin käyttö antiaterogeenisenä aineena - Google Patents

Nebivololin käyttö antiaterogeenisenä aineena Download PDF

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Publication number
FI972793A
FI972793A FI972793A FI972793A FI972793A FI 972793 A FI972793 A FI 972793A FI 972793 A FI972793 A FI 972793A FI 972793 A FI972793 A FI 972793A FI 972793 A FI972793 A FI 972793A
Authority
FI
Finland
Prior art keywords
antiatherogenic
nebivolol
substance
alpha
chromanmethanol
Prior art date
Application number
FI972793A
Other languages
English (en)
Swedish (sv)
Other versions
FI972793A0 (fi
FI118884B (fi
Inventor
Chaffoy De Courcelles Didie De
Anne Simone Josephine Lesage
Josepha Eduarda Maria F Leysen
Original Assignee
Janssen Pharmaceutica Nv
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Janssen Pharmaceutica Nv filed Critical Janssen Pharmaceutica Nv
Publication of FI972793A publication Critical patent/FI972793A/fi
Publication of FI972793A0 publication Critical patent/FI972793A0/fi
Application granted granted Critical
Publication of FI118884B publication Critical patent/FI118884B/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/33—Heterocyclic compounds
    • A61K31/335—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin
    • A61K31/35—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom
    • A61K31/352—Heterocyclic compounds having oxygen as the only ring hetero atom, e.g. fungichromin having six-membered rings with one oxygen as the only ring hetero atom condensed with carbocyclic rings, e.g. methantheline 
    • A61K31/353—3,4-Dihydrobenzopyrans, e.g. chroman, catechin
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
FI972793A 1994-12-28 1997-06-27 Nebivololin käyttö antiaterogeenisenä aineena FI118884B (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
EP94203775 1994-12-28
EP94203775 1994-12-28
PCT/EP1995/005174 WO1996019987A1 (en) 1994-12-28 1995-12-21 Use of nebivolol as an anti-atherogenic
EP9505174 1995-12-21

Publications (3)

Publication Number Publication Date
FI972793A true FI972793A (fi) 1997-06-27
FI972793A0 FI972793A0 (fi) 1997-06-27
FI118884B FI118884B (fi) 2008-04-30

Family

ID=8217503

Family Applications (1)

Application Number Title Priority Date Filing Date
FI972793A FI118884B (fi) 1994-12-28 1997-06-27 Nebivololin käyttö antiaterogeenisenä aineena

Country Status (20)

Country Link
US (2) US5874461A (fi)
EP (1) EP0801564B1 (fi)
JP (1) JPH10511655A (fi)
KR (1) KR100264348B1 (fi)
CN (1) CN1167418C (fi)
AT (1) ATE214924T1 (fi)
AU (1) AU700364B2 (fi)
CA (1) CA2207333C (fi)
CZ (1) CZ287513B6 (fi)
DE (1) DE69526120T2 (fi)
DK (1) DK0801564T3 (fi)
ES (1) ES2176354T3 (fi)
FI (1) FI118884B (fi)
HU (1) HU226208B1 (fi)
NO (1) NO315687B1 (fi)
NZ (1) NZ298074A (fi)
PT (1) PT801564E (fi)
SI (1) SI0801564T1 (fi)
SK (1) SK282144B6 (fi)
WO (1) WO1996019987A1 (fi)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2207333C (en) * 1994-12-28 2006-10-17 Janssen Pharmaceutica, Naamloze Vennootschap Use of nebivolol as an anti-atherogenic
DE19716120A1 (de) * 1997-04-17 1998-10-22 Europ Lab Molekularbiolog Verwendung von cholesterinsenkenden Mitteln
US6362371B1 (en) 1998-06-08 2002-03-26 Advanced Medicine, Inc. β2- adrenergic receptor agonists
US6713651B1 (en) 1999-06-07 2004-03-30 Theravance, Inc. β2-adrenergic receptor agonists
JP2000207219A (ja) * 1999-01-18 2000-07-28 Fujitsu Ten Ltd 車載端末とセンタ―との間の通信システム、及び、通信システムに使用する車載端末
US6683115B2 (en) 1999-06-02 2004-01-27 Theravance, Inc. β2-adrenergic receptor agonists
US6593497B1 (en) 1999-06-02 2003-07-15 Theravance, Inc. β2-adrenergic receptor agonists
UA73965C2 (en) 1999-12-08 2005-10-17 Theravance Inc b2 ADRENERGIC RECEPTOR ANTAGONISTS
DE60233140D1 (de) 2001-05-02 2009-09-10 Nitromed Inc Nitrosiertes und nitrosyliertes nebivolol und seine metaboliten, zusammensetzungen und anwendungsverfahren
CA2504334A1 (en) * 2002-10-30 2004-05-21 Galileo Pharmaceuticals, Inc. Identifying therapeutic compounds based on their physical-chemical properties
ITTO20030140U1 (it) * 2003-09-16 2005-03-17 Interfila Srl Matita cosmetica
WO2005032544A1 (en) * 2003-09-19 2005-04-14 Galileo Pharmaceuticals, Inc. Treatment of mitochondrial diseases
US7803838B2 (en) 2004-06-04 2010-09-28 Forest Laboratories Holdings Limited Compositions comprising nebivolol
US7838552B2 (en) 2004-06-04 2010-11-23 Forest Laboratories Holdings Limited Compositions comprising nebivolol
RU2378272C2 (ru) 2004-07-30 2010-01-10 Торрент Фармасьютикалз Лимитед Небиволол и его фармацевтически приемлемые соли, способ их получения и фармацевтические композиции небиволола
JP2008528626A (ja) * 2005-01-31 2008-07-31 マイラン ラボラトリーズ インク． ヒドロキシル化されたネビボロールを含む薬学的組成物
EP2471530B1 (en) 2005-06-01 2017-01-11 Edison Pharmaceuticals, Inc. Redox-active therapeutics for treatment of mitochondrial diseases and other conditions and modulation of energy biomarkers
JP5374162B2 (ja) 2006-02-22 2013-12-25 エジソン ファーマシューティカルズ， インコーポレイテッド ミトコンドリア病および他の症状の処置のためのレドックス活性化治療の側鎖変異体およびエネルギーバイオマーカーの調節
EA038941B1 (ru) 2007-11-06 2021-11-12 ПиТиСи ТЕРАПЬЮТИКС, ИНК. ПРОИЗВОДНЫЕ 4-(п-ХИНОНИЛ)-2-ГИДРОКСИБУТАНАМИДА ДЛЯ ЛЕЧЕНИЯ МИТОХОНДРИАЛЬНЫХ ЗАБОЛЕВАНИЙ
US20090181975A1 (en) * 2008-01-15 2009-07-16 Forest Laboratories Holdings Limited Nebivolol in the treatment of sexual dysfunction
CA2717734A1 (en) 2008-03-05 2009-09-11 Edison Pharmaceuticals, Inc 2-substituted-p-quinone derivatives for treatment of oxidative stress diseases
CA2736250C (en) 2008-09-10 2016-12-20 Edison Pharmaceuticals, Inc. Treatment of pervasive developmental disorders with redox-active therapeutics
EP2362726B1 (en) 2008-10-14 2018-08-08 Bioelectron Technology Corporation Treatment of oxidative stress disorders including contrast nephropathy, radiation damage and disruptions in the function of red cells
US20110250644A1 (en) * 2008-12-19 2011-10-13 Schering Corporation Feed supplement for mammalian cell culture and methods of use
PL2424495T3 (pl) 2009-04-28 2018-06-29 Bioelectron Technology Corporation Leczenie dziedzicznej neuropatii nerwów wzrokowych lebera i dominującego zaniku nerwu wzrokowego chinonami tokotrienolu
HK1161509A2 (en) * 2010-06-04 2012-07-27 Comprehensive Drug Entpr Ltd Oral meclizine aqueous formulations with taste flavoring agent
US9670170B2 (en) 2013-03-15 2017-06-06 Bioelectron Technology Corporation Resorufin derivatives for treatment of oxidative stress disorders
US9296712B2 (en) 2013-03-15 2016-03-29 Edison Pharmaceuticals, Inc. Resorufin derivatives for treatment of oxidative stress disorders
US9868711B2 (en) 2013-03-15 2018-01-16 Bioelectron Technology Corporation Phenazine-3-one and phenothiazine-3-one derivatives for treatment of oxidative stress disorders
DE102014107132A1 (de) 2014-05-20 2015-11-26 Corden Pharma International Gmbh Verfahren zur Herstellung von Epoxiden die in der Herstellung von Nebivolol und dessen Derivaten einsetzbar sind
WO2016062265A1 (zh) * 2014-10-24 2016-04-28 朗齐生物医学股份有限公司 莫诺苯宗药物在用于制备治疗癌症的医药组合物中的用途
ES2912585T3 (es) 2014-12-16 2022-05-26 Ptc Therapeutics Inc Formas polimórficas y amorfas de la (R)-2-hidroxi-2-metil-4-(2,4,5-trimetil-3,6-dioxociclohexa-1,4-dienil)butanamida
CN113024369A (zh) 2015-12-17 2021-06-25 Ptc医疗公司 用于治疗氧化应急障碍的化合物

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1337432C (en) * 1988-03-23 1995-10-24 Raymond M. Xhonneux Method of lowering the blood pressure
TW355683B (en) * 1994-02-17 1999-04-11 Janssen Pharmaceutica Nv Composition containing micronized nebivolol
CA2207333C (en) * 1994-12-28 2006-10-17 Janssen Pharmaceutica, Naamloze Vennootschap Use of nebivolol as an anti-atherogenic

Also Published As

Publication number Publication date
DK0801564T3 (da) 2002-07-15
CA2207333C (en) 2006-10-17
SI0801564T1 (en) 2002-08-31
PT801564E (pt) 2002-09-30
EP0801564B1 (en) 2002-03-27
FI972793A0 (fi) 1997-06-27
CZ287513B6 (en) 2000-12-13
HUT77927A (hu) 1998-11-30
SK282144B6 (sk) 2001-11-06
CN1171739A (zh) 1998-01-28
DE69526120T2 (de) 2002-11-28
AU4347796A (en) 1996-07-19
KR100264348B1 (ko) 2000-08-16
AU700364B2 (en) 1999-01-07
NO972980D0 (no) 1997-06-26
FI118884B (fi) 2008-04-30
NO315687B1 (no) 2003-10-13
NZ298074A (en) 2001-01-26
WO1996019987A1 (en) 1996-07-04
CA2207333A1 (en) 1996-07-04
SK85697A3 (en) 2000-04-10
HU226208B1 (en) 2008-06-30
CZ191997A3 (cs) 1999-01-13
MX9704669A (es) 1997-09-30
DE69526120D1 (de) 2002-05-02
US5874461A (en) 1999-02-23
JPH10511655A (ja) 1998-11-10
ES2176354T3 (es) 2002-12-01
NO972980L (no) 1997-06-26
ATE214924T1 (de) 2002-04-15
US6075046A (en) 2000-06-13
EP0801564A1 (en) 1997-10-22
CN1167418C (zh) 2004-09-22

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