FI970892A - Ilmentymiseltään kohdennetut retrovirusvektorit, jotka eivät ole itsestään inaktivoivia - Google Patents

Ilmentymiseltään kohdennetut retrovirusvektorit, jotka eivät ole itsestään inaktivoivia Download PDF

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Publication number
FI970892A
FI970892A FI970892A FI970892A FI970892A FI 970892 A FI970892 A FI 970892A FI 970892 A FI970892 A FI 970892A FI 970892 A FI970892 A FI 970892A FI 970892 A FI970892 A FI 970892A
Authority
FI
Finland
Prior art keywords
region
inactivating
expression
self
retroviral vectors
Prior art date
Application number
FI970892A
Other languages
English (en)
Swedish (sv)
Other versions
FI970892A0 (fi
Inventor
Walter Henry Guenzburg
Robert Michael Saller
Original Assignee
Gsf Forschungszentrum Umwelt
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Gsf Forschungszentrum Umwelt filed Critical Gsf Forschungszentrum Umwelt
Publication of FI970892A publication Critical patent/FI970892A/fi
Publication of FI970892A0 publication Critical patent/FI970892A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/63Introduction of foreign genetic material using vectors; Vectors; Use of hosts therefor; Regulation of expression
    • C12N15/79Vectors or expression systems specially adapted for eukaryotic hosts
    • C12N15/85Vectors or expression systems specially adapted for eukaryotic hosts for animal cells
    • C12N15/86Viral vectors
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12Antivirals
    • A61P31/14Antivirals for RNA viruses
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N2740/00Reverse transcribing RNA viruses
    • C12N2740/00011Details
    • C12N2740/10011Retroviridae
    • C12N2740/13011Gammaretrovirus, e.g. murine leukeamia virus
    • C12N2740/13041Use of virus, viral particle or viral elements as a vector
    • C12N2740/13043Use of virus, viral particle or viral elements as a vector viral genome or elements thereof as genetic vector
FI970892A 1994-09-02 1997-02-28 Ilmentymiseltään kohdennetut retrovirusvektorit, jotka eivät ole itsestään inaktivoivia FI970892A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK101794 1994-09-02
PCT/EP1995/003445 WO1996007748A1 (en) 1994-09-02 1995-09-01 Non self-inactivating, expression targeted retroviral vectors

Publications (2)

Publication Number Publication Date
FI970892A true FI970892A (fi) 1997-02-28
FI970892A0 FI970892A0 (fi) 1997-02-28

Family

ID=8100062

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970892A FI970892A0 (fi) 1994-09-02 1997-02-28 Ilmentymiseltään kohdennetut retrovirusvektorit, jotka eivät ole itsestään inaktivoivia

Country Status (21)

Country Link
US (1) US7531353B1 (fi)
EP (1) EP0779929B1 (fi)
JP (1) JP4037446B2 (fi)
CN (1) CN1117156C (fi)
AT (1) ATE200517T1 (fi)
AU (1) AU688590B2 (fi)
BR (1) BR9508664A (fi)
CA (1) CA2198210C (fi)
DE (1) DE69520681T2 (fi)
DK (1) DK0779929T5 (fi)
EE (1) EE03492B1 (fi)
ES (1) ES2156945T3 (fi)
FI (1) FI970892A0 (fi)
HK (1) HK1001527A1 (fi)
HU (1) HU221607B (fi)
MX (1) MX9701544A (fi)
NO (1) NO317731B1 (fi)
NZ (1) NZ292897A (fi)
PL (1) PL184375B1 (fi)
RU (1) RU2199585C2 (fi)
WO (1) WO1996007748A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA2198210C (en) 1994-09-02 2006-07-11 Walter Henry Gunzburg Non self-inactivating, expression targeted retroviral vectors
ES2198479T3 (es) 1995-03-09 2004-02-01 Gsf-Forschungszentrum Fur Umwelt Und Gesundheit Gmbh Vectores que llevan genes terapeuticos codificantes de peptidos antimicrobianos para terapia genica.
PT835137E (pt) 1995-06-27 2004-12-31 Gsf Forschungszentrum Umwelt U Celulas encapsuladas produtoras de particulas virais
EP0859854B1 (en) * 1995-10-13 2002-05-02 Austrian Nordic Biotherapeutics AG Retroviral vectors carrying senescent cell derived inhibitors 1 (sdi-1) or antisense sdi-1 nucleotide sequences
US7074398B1 (en) 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences
US6540995B1 (en) 1996-03-27 2003-04-01 Bavarian Nordic Research Institute Gmbh Encapsulated cells producing cytochrome P450
RU2223788C2 (ru) 1996-03-27 2004-02-20 Бавариан Нордик Рисерч Инститьют А/С Трансдуцирующие цитохром p450 ретровирусные векторы
WO1998032869A1 (en) * 1997-01-29 1998-07-30 Neurosearch A/S Expression vectors and methods for in vivo expression of therapeutic polypeptides
CN1322137C (zh) * 1997-12-22 2007-06-20 牛津生物医学(英国)有限公司 基于马传染性贫血病毒(eiav)的逆转录病毒载体
DE69920659T2 (de) 1998-01-06 2006-03-09 Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien Rekonstituierender retroviraler vektor (recon vektor) für gezielte genexpression
FR2778670B1 (fr) * 1998-05-18 2002-12-13 Rhone Poulenc Rorer Sa Methodes et compositions pour la production de particules virales
DE19910650A1 (de) * 1999-03-10 2000-09-21 Gsf Forschungszentrum Umwelt Auf HERV-LTR-Sequenzen basierende retrovirale Expressionsvektoren
JP2002542834A (ja) * 1999-04-29 2002-12-17 アールフス・ユニバーシティー レトロウイルスベクターでのires転写カセットからの異種遺伝子群の発現
WO2002064805A2 (en) * 2001-02-09 2002-08-22 Institut für Virologie Teilrechtsfähiges Institut an der Veterinärmedizinischen Universität Wien Replication competent non-mammalian retroviral vectors
DE102009021592A1 (de) * 2009-05-15 2010-11-18 Medizinische Hochschule Hannover ASLV-Vektorsystem

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO1989011539A1 (en) 1988-05-17 1989-11-30 Sloan-Kettering Institute For Cancer Research Retroviral vector
GB8919607D0 (en) * 1989-08-30 1989-10-11 Wellcome Found Novel entities for cancer therapy
WO1994029437A1 (en) * 1993-06-07 1994-12-22 University Of Medicine & Dentistry Of New Jersey Highly-efficient, self-inactivating, recombination-free, u3-free retroviral vectors
CA2198210C (en) 1994-09-02 2006-07-11 Walter Henry Gunzburg Non self-inactivating, expression targeted retroviral vectors
ES2198479T3 (es) * 1995-03-09 2004-02-01 Gsf-Forschungszentrum Fur Umwelt Und Gesundheit Gmbh Vectores que llevan genes terapeuticos codificantes de peptidos antimicrobianos para terapia genica.
EP0817859B1 (en) * 1995-03-09 2002-01-16 Austrian Nordic Biotherapeutics AG Recombinant dna vectors for gene therapy
US6117681A (en) * 1995-03-29 2000-09-12 Bavarian Nordic Research Inst. A/S Pseudotyped retroviral particles
GB9510272D0 (en) 1995-05-22 1995-07-19 Isis Innovation Retroviral vectors
US7074398B1 (en) * 1995-10-13 2006-07-11 Gsf-Forschungszentrum Fuer Umwelt Und Gesundheit Gmbh Retroviral vectors carrying senescent cell derived inhibitors 1 (SDI-1)or antisense SDI-1 nucleotide sequences

Also Published As

Publication number Publication date
EE03492B1 (et) 2001-08-15
WO1996007748A1 (en) 1996-03-14
HU221607B (hu) 2002-11-28
CA2198210A1 (en) 1996-03-14
BR9508664A (pt) 1998-01-06
CN1117156C (zh) 2003-08-06
PL319033A1 (en) 1997-07-21
CN1159210A (zh) 1997-09-10
JPH10507628A (ja) 1998-07-28
AU688590B2 (en) 1998-03-12
RU2199585C2 (ru) 2003-02-27
NO317731B1 (no) 2004-12-13
PL184375B1 (pl) 2002-10-31
HUT76974A (hu) 1998-01-28
DE69520681D1 (de) 2001-05-17
ES2156945T3 (es) 2001-08-01
US7531353B1 (en) 2009-05-12
MX9701544A (es) 1998-03-31
ATE200517T1 (de) 2001-04-15
EE9700040A (et) 1997-08-15
AU3520195A (en) 1996-03-27
NO970902D0 (no) 1997-02-27
NO970902L (no) 1997-04-24
JP4037446B2 (ja) 2008-01-23
NZ292897A (en) 1998-08-26
EP0779929A1 (en) 1997-06-25
HK1001527A1 (en) 1998-06-26
DK0779929T3 (da) 2001-05-07
FI970892A0 (fi) 1997-02-28
EP0779929B1 (en) 2001-04-11
CA2198210C (en) 2006-07-11
DK0779929T5 (da) 2001-08-13
DE69520681T2 (de) 2001-11-29

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