DE69403642D1 - 7-deazapurin modifizierte oligonukleotide - Google Patents
7-deazapurin modifizierte oligonukleotideInfo
- Publication number
- DE69403642D1 DE69403642D1 DE69403642T DE69403642T DE69403642D1 DE 69403642 D1 DE69403642 D1 DE 69403642D1 DE 69403642 T DE69403642 T DE 69403642T DE 69403642 T DE69403642 T DE 69403642T DE 69403642 D1 DE69403642 D1 DE 69403642D1
- Authority
- DE
- Germany
- Prior art keywords
- deazapurin
- modified oligonucleotides
- oligonucleotides
- deazanucleosides
- rna
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
- C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P35/00—Antineoplastic agents
Landscapes
- Health & Medical Sciences (AREA)
- Chemical & Material Sciences (AREA)
- Life Sciences & Earth Sciences (AREA)
- Organic Chemistry (AREA)
- General Health & Medical Sciences (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Molecular Biology (AREA)
- Pharmacology & Pharmacy (AREA)
- General Chemical & Material Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Biochemistry (AREA)
- Medicinal Chemistry (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Genetics & Genomics (AREA)
- Virology (AREA)
- Communicable Diseases (AREA)
- Oncology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Saccharide Compounds (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
US4015893A | 1993-03-30 | 1993-03-30 | |
PCT/US1994/002996 WO1994022892A1 (en) | 1993-03-30 | 1994-03-21 | 7-deazapurine modified oligonucleotides |
Publications (2)
Publication Number | Publication Date |
---|---|
DE69403642D1 true DE69403642D1 (de) | 1997-07-10 |
DE69403642T2 DE69403642T2 (de) | 1998-01-08 |
Family
ID=21909441
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
DE69403642T Expired - Fee Related DE69403642T2 (de) | 1993-03-30 | 1994-03-21 | 7-deazapurin modifizierte oligonukleotide |
Country Status (11)
Country | Link |
---|---|
EP (1) | EP0691980B1 (de) |
JP (1) | JPH08508493A (de) |
AT (1) | ATE154029T1 (de) |
AU (1) | AU6589094A (de) |
CA (1) | CA2159630A1 (de) |
DE (1) | DE69403642T2 (de) |
DK (1) | DK0691980T3 (de) |
ES (1) | ES2105698T3 (de) |
GR (1) | GR3024597T3 (de) |
HU (1) | HU9501963D0 (de) |
WO (1) | WO1994022892A1 (de) |
Families Citing this family (36)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4438918A1 (de) | 1994-11-04 | 1996-05-09 | Hoechst Ag | Modifizierte Oligonukleotide, deren Herstellung sowie deren Verwendung |
US6150510A (en) * | 1995-11-06 | 2000-11-21 | Aventis Pharma Deutschland Gmbh | Modified oligonucleotides, their preparation and their use |
GB2323357B (en) * | 1997-03-20 | 1999-09-29 | Amersham Pharm Biotech Inc | Derivatives of 7-deaza-2-deoxy-guanosine-5'-triphosphate, preparation and use thereof |
US6906185B1 (en) | 1997-03-20 | 2005-06-14 | Amersham Biosciences Corp. | Derivatives of 7-deaza -2′-deoxyguanosine-5'-triphosphate, preparation and use thereof |
US6660845B1 (en) * | 1999-11-23 | 2003-12-09 | Epoch Biosciences, Inc. | Non-aggregating, non-quenching oligomers comprising nucleotide analogues; methods of synthesis and use thereof |
US6962906B2 (en) | 2000-03-14 | 2005-11-08 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
WO2001068673A1 (en) | 2000-03-14 | 2001-09-20 | Active Motif | Oligonucleotide analogues, methods of synthesis and methods of use |
EP1322656B1 (de) * | 2000-09-26 | 2008-01-16 | Idera Pharmaceuticals, Inc. | Modulation der immunostimulatorischen aktivität von immunostimulierenden oligonukleotidanaloga durch positionelle chemische veränderungen |
CA2691364C (en) | 2007-06-19 | 2020-06-16 | Stratos Genomics, Inc. | High throughput nucleic acid sequencing by expansion |
CN102365367A (zh) | 2009-01-29 | 2012-02-29 | 斯特拉托斯基因公司 | 通过展开进行高通量核酸测序和相关方法 |
US8586301B2 (en) | 2010-06-30 | 2013-11-19 | Stratos Genomics, Inc. | Multiplexed identification of nucleic acid sequences |
US9212392B2 (en) | 2012-09-25 | 2015-12-15 | Exact Sciences Corporation | Normalization of polymerase activity |
US20140287946A1 (en) | 2013-03-14 | 2014-09-25 | Ibis Biosciences, Inc. | Nucleic acid control panels |
US10301345B2 (en) | 2014-11-20 | 2019-05-28 | Stratos Genomics, Inc. | Phosphoroamidate esters, and use and synthesis thereof |
EP3368686A1 (de) | 2015-10-30 | 2018-09-05 | Exact Sciences Development Company, LLC | Test für den nachweis von multiplexamplifikation und -isolierung und nachweis von dann aus plasma |
ES2846949T3 (es) | 2015-11-16 | 2021-07-30 | Stratos Genomics Inc | Variantes de la polimerasa DPO4 |
CN116064796A (zh) | 2016-05-05 | 2023-05-05 | 精密科学公司 | 通过分析甲基化dna来检测肺肿瘤 |
AU2018211956A1 (en) | 2017-01-27 | 2019-07-25 | Exact Sciences Corporation | Detection of colon neoplasia by analysis of methylated DNA |
US11261440B2 (en) | 2017-02-21 | 2022-03-01 | Osaka University | Antisense oligonucleic acid |
US11708566B2 (en) | 2017-05-04 | 2023-07-25 | Stratos Genomics, Inc. | DP04 polymerase variants |
CA3084812A1 (en) | 2017-12-11 | 2019-06-20 | Stratos Genomics, Inc. | Dpo4 polymerase variants with improved accuracy |
US10648025B2 (en) | 2017-12-13 | 2020-05-12 | Exact Sciences Development Company, Llc | Multiplex amplification detection assay II |
US20220403450A1 (en) | 2021-06-03 | 2022-12-22 | Illumina Software, Inc. | Systems and methods for sequencing nucleotides using two optical channels |
CA3223131A1 (en) | 2021-07-01 | 2023-01-05 | Rean Silke MUSA | Device having horizontal nanochannel for nanopore sequencing |
WO2023034079A1 (en) | 2021-09-01 | 2023-03-09 | Illumina Software, Inc. | Amplitude modulation for accelerated base calling |
US20230090867A1 (en) | 2021-09-22 | 2023-03-23 | Illumina, Inc. | Sequencing polynucleotides using nanopores |
US20230112203A1 (en) | 2021-09-30 | 2023-04-13 | Illumina, Inc. | Isolation of cells in a nanopore sensor array |
WO2023086391A1 (en) | 2021-11-15 | 2023-05-19 | Illumina, Inc. | Nanopore systems and methods of fabrication |
WO2023107622A1 (en) | 2021-12-10 | 2023-06-15 | Illumina, Inc. | Parallel sample and index sequencing |
WO2023175018A1 (en) | 2022-03-15 | 2023-09-21 | Illumina, Inc. | Concurrent sequencing of forward and reverse complement strands on separate polynucleotides |
US20230357307A1 (en) | 2022-05-04 | 2023-11-09 | Illumina, Inc. | Cleavable cyclic loop nucleotides for nanopore sequencing |
WO2023239660A1 (en) | 2022-06-07 | 2023-12-14 | Illumina Software, Inc. | Methods and systems for identifying gene variants |
WO2024010812A2 (en) | 2022-07-07 | 2024-01-11 | Illumina Software, Inc. | Methods and systems for determining copy number variant genotypes |
WO2024010809A2 (en) | 2022-07-07 | 2024-01-11 | Illumina Software, Inc. | Methods and systems for detecting recombination events |
WO2024073278A1 (en) | 2022-09-26 | 2024-04-04 | Illumina, Inc. | Detecting and genotyping variable number tandem repeats |
WO2024072685A1 (en) | 2022-09-28 | 2024-04-04 | Illumina, Inc. | Fast pulsing for nanopore sensors |
Family Cites Families (1)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE3739366A1 (de) * | 1987-04-10 | 1988-10-27 | Boehringer Mannheim Gmbh | Desaza-purin-nucleosid-derivate, verfahren zu deren herstellung sowie deren verwendung bei der nucleinsaeure-sequenzierung sowie als antivirale mittel |
-
1994
- 1994-03-21 CA CA002159630A patent/CA2159630A1/en not_active Abandoned
- 1994-03-21 WO PCT/US1994/002996 patent/WO1994022892A1/en active IP Right Grant
- 1994-03-21 JP JP6522134A patent/JPH08508493A/ja active Pending
- 1994-03-21 ES ES94913923T patent/ES2105698T3/es not_active Expired - Lifetime
- 1994-03-21 AT AT94913923T patent/ATE154029T1/de not_active IP Right Cessation
- 1994-03-21 AU AU65890/94A patent/AU6589094A/en not_active Abandoned
- 1994-03-21 HU HU9501963A patent/HU9501963D0/hu unknown
- 1994-03-21 EP EP94913923A patent/EP0691980B1/de not_active Expired - Lifetime
- 1994-03-21 DE DE69403642T patent/DE69403642T2/de not_active Expired - Fee Related
- 1994-03-21 DK DK94913923.2T patent/DK0691980T3/da active
-
1997
- 1997-09-02 GR GR970402241T patent/GR3024597T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HU9501963D0 (en) | 1995-08-28 |
AU6589094A (en) | 1994-10-24 |
DE69403642T2 (de) | 1998-01-08 |
ATE154029T1 (de) | 1997-06-15 |
CA2159630A1 (en) | 1994-10-13 |
ES2105698T3 (es) | 1997-10-16 |
GR3024597T3 (en) | 1997-12-31 |
WO1994022892A1 (en) | 1994-10-13 |
EP0691980B1 (de) | 1997-06-04 |
DK0691980T3 (da) | 1997-12-29 |
EP0691980A1 (de) | 1996-01-17 |
JPH08508493A (ja) | 1996-09-10 |
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Legal Events
Date | Code | Title | Description |
---|---|---|---|
8364 | No opposition during term of opposition | ||
8339 | Ceased/non-payment of the annual fee |