FI970564A0 - Uusi menetelmä di-isopinokamfeyyliklooriboraanin valmistamiseksi - Google Patents
Uusi menetelmä di-isopinokamfeyyliklooriboraanin valmistamiseksiInfo
- Publication number
- FI970564A0 FI970564A0 FI970564A FI970564A FI970564A0 FI 970564 A0 FI970564 A0 FI 970564A0 FI 970564 A FI970564 A FI 970564A FI 970564 A FI970564 A FI 970564A FI 970564 A0 FI970564 A0 FI 970564A0
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- new process
- diisopinocampheylchloroborane
- diisopinocampheyl
- chloroborane
- Prior art date
Links
- 238000000034 method Methods 0.000 title abstract 2
- 238000002360 preparation method Methods 0.000 title abstract 2
- UOALEFQKAOQICC-UHFFFAOYSA-N chloroborane Chemical compound ClB UOALEFQKAOQICC-UHFFFAOYSA-N 0.000 title 1
- GRWFGVWFFZKLTI-UHFFFAOYSA-N α-pinene Chemical compound CC1=CCC2C(C)(C)C1C2 GRWFGVWFFZKLTI-UHFFFAOYSA-N 0.000 abstract 2
- GRWFGVWFFZKLTI-IUCAKERBSA-N 1S,5S-(-)-alpha-Pinene Natural products CC1=CC[C@@H]2C(C)(C)[C@H]1C2 GRWFGVWFFZKLTI-IUCAKERBSA-N 0.000 abstract 1
- 150000001298 alcohols Chemical class 0.000 abstract 1
- MVNCAPSFBDBCGF-UHFFFAOYSA-N alpha-pinene Natural products CC1=CCC23C1CC2C3(C)C MVNCAPSFBDBCGF-UHFFFAOYSA-N 0.000 abstract 1
- 238000011065 in-situ storage Methods 0.000 abstract 1
- 238000002955 isolation Methods 0.000 abstract 1
- 150000002576 ketones Chemical class 0.000 abstract 1
- 230000003287 optical effect Effects 0.000 abstract 1
- 229910000033 sodium borohydride Inorganic materials 0.000 abstract 1
- 239000012279 sodium borohydride Substances 0.000 abstract 1
- FAQYAMRNWDIXMY-UHFFFAOYSA-N trichloroborane Chemical compound ClB(Cl)Cl FAQYAMRNWDIXMY-UHFFFAOYSA-N 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/12—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D215/14—Radicals substituted by oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D215/00—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems
- C07D215/02—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom
- C07D215/16—Heterocyclic compounds containing quinoline or hydrogenated quinoline ring systems having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen atoms or carbon atoms directly attached to the ring nitrogen atom with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D215/18—Halogen atoms or nitro radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F5/00—Compounds containing elements of Groups 3 or 13 of the Periodic Table
- C07F5/02—Boron compounds
- C07F5/027—Organoboranes and organoborohydrides
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Polysaccharides And Polysaccharide Derivatives (AREA)
- Detergent Compositions (AREA)
- Cephalosporin Compounds (AREA)
- Medicinal Preparation (AREA)
- Lock And Its Accessories (AREA)
- Lubricants (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US08/289,077 US5545758A (en) | 1994-08-11 | 1994-08-11 | Process for the preparation of diisopinocampheylchloroborane |
| US28907794 | 1994-08-11 | ||
| US9509921 | 1995-08-07 | ||
| PCT/US1995/009921 WO1996005206A1 (en) | 1994-08-11 | 1995-08-07 | Novel process for the preparation of diisopinocampheylchloroborane |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI970564A FI970564A (fi) | 1997-02-10 |
| FI970564A0 true FI970564A0 (fi) | 1997-02-10 |
| FI120347B FI120347B (fi) | 2009-09-30 |
Family
ID=23109960
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI970564A FI120347B (fi) | 1994-08-11 | 1997-02-10 | Uusi menetelmä di-isopinokamfeyyliklooriboraanin valmistamiseksi ja menetelmä prokiraalisen ketonin pelkistämiseksi |
Country Status (23)
| Country | Link |
|---|---|
| US (2) | US5545758A (fi) |
| EP (1) | EP0775146B1 (fi) |
| JP (1) | JPH10504307A (fi) |
| KR (1) | KR100355916B1 (fi) |
| CN (2) | CN1051087C (fi) |
| AT (1) | ATE219087T1 (fi) |
| AU (1) | AU693588B2 (fi) |
| BR (1) | BR9508578A (fi) |
| CA (1) | CA2195776C (fi) |
| CZ (2) | CZ286602B6 (fi) |
| DE (1) | DE69527070T2 (fi) |
| DK (1) | DK0775146T3 (fi) |
| ES (1) | ES2176335T3 (fi) |
| FI (1) | FI120347B (fi) |
| HU (1) | HU215183B (fi) |
| MX (1) | MX9701087A (fi) |
| NZ (1) | NZ291101A (fi) |
| PT (1) | PT775146E (fi) |
| RO (1) | RO115882B1 (fi) |
| RU (1) | RU2150472C1 (fi) |
| SI (1) | SI0775146T1 (fi) |
| UA (1) | UA46741C2 (fi) |
| WO (1) | WO1996005206A1 (fi) |
Families Citing this family (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| KR100581647B1 (ko) * | 2001-07-17 | 2006-05-22 | 파마시아 앤드 업존 캄파니 엘엘씨 | 라타노프로스트 제조를 위한 방법 및 중간체 |
| WO2006021974A1 (en) * | 2004-08-23 | 2006-03-02 | Morepen Laboratories Limited | A process for synthesizing diol (viii)-an intermediate of montelukast sodium |
| US20060223999A1 (en) * | 2006-05-10 | 2006-10-05 | Chemagis Ltd. | Process for preparing montelukast and precursors thereof |
| CN101225089B (zh) * | 2007-01-17 | 2011-06-15 | 上海迪赛诺医药发展有限公司 | 制备二异松蒎基氯甲硼烷的方法 |
| CN101889081B (zh) * | 2007-09-28 | 2014-06-18 | 科德克希思公司 | 酮还原酶多肽及其用途 |
| US20100055052A1 (en) * | 2008-08-26 | 2010-03-04 | James Albert Berta | Processing System for Oral Care Compositions |
| CN101525344B (zh) * | 2009-04-09 | 2011-10-05 | 霸州市路德精细化工有限公司 | 异松蒎基硼烷氯化物的制备方法 |
| CN103030658B (zh) * | 2012-06-29 | 2015-08-19 | 山东威智医药工业有限公司 | 二异松蒎基氯甲硼烷的工业化生产方法 |
| CN103601708B (zh) * | 2013-12-11 | 2015-06-17 | 武汉武药科技有限公司 | 一种前列素药物杂质的制备方法 |
Family Cites Families (6)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5043479A (en) * | 1986-08-29 | 1991-08-27 | Aldrich Chemical Company, Inc. | Chemically and optically pure diisopinocampheylhaloboranes |
| CA2050820A1 (en) * | 1990-09-24 | 1992-03-25 | Pamela M. Simpson | In-situ preparation of diisopinocamphenyl chloroborane |
| US5159116A (en) * | 1991-07-15 | 1992-10-27 | Aldrich Chemical Company, Inc. | Chemically and optically pure B-halodiiso-2-ethylapopinocampheylboranes |
| US5220072A (en) * | 1991-07-15 | 1993-06-15 | Aldrich Chemical Co., Inc. | Process of synthesizing chemically and optically pure B-halodiiso-2-ethylapopinocampheylboranes |
| US5270324A (en) * | 1992-04-10 | 1993-12-14 | Merck Frosst Canada, Inc. | Fluorinated hydroxyalkylquinoline acids as leukotriene antagonists |
| US5220077A (en) * | 1992-08-19 | 1993-06-15 | Vista Chemical Company | Alkoxylation process |
-
1994
- 1994-08-11 US US08/289,077 patent/US5545758A/en not_active Expired - Lifetime
-
1995
- 1995-08-07 AT AT95928320T patent/ATE219087T1/de active
- 1995-08-07 UA UA97031025A patent/UA46741C2/uk unknown
- 1995-08-07 CZ CZ1997387A patent/CZ286602B6/cs not_active IP Right Cessation
- 1995-08-07 WO PCT/US1995/009921 patent/WO1996005206A1/en active IP Right Grant
- 1995-08-07 CZ CZ19993445A patent/CZ294311B6/cs not_active IP Right Cessation
- 1995-08-07 HU HU9701953A patent/HU215183B/hu not_active IP Right Cessation
- 1995-08-07 AU AU32135/95A patent/AU693588B2/en not_active Ceased
- 1995-08-07 NZ NZ291101A patent/NZ291101A/en not_active IP Right Cessation
- 1995-08-07 RO RO97-00268A patent/RO115882B1/ro unknown
- 1995-08-07 MX MX9701087A patent/MX9701087A/es unknown
- 1995-08-07 BR BR9508578A patent/BR9508578A/pt not_active IP Right Cessation
- 1995-08-07 JP JP8507416A patent/JPH10504307A/ja not_active Ceased
- 1995-08-07 SI SI9530597T patent/SI0775146T1/xx unknown
- 1995-08-07 DK DK95928320T patent/DK0775146T3/da active
- 1995-08-07 CA CA002195776A patent/CA2195776C/en not_active Expired - Fee Related
- 1995-08-07 EP EP95928320A patent/EP0775146B1/en not_active Expired - Lifetime
- 1995-08-07 PT PT95928320T patent/PT775146E/pt unknown
- 1995-08-07 DE DE69527070T patent/DE69527070T2/de not_active Expired - Lifetime
- 1995-08-07 KR KR1019970700854A patent/KR100355916B1/ko not_active IP Right Cessation
- 1995-08-07 CN CN95195485A patent/CN1051087C/zh not_active Expired - Fee Related
- 1995-08-07 ES ES95928320T patent/ES2176335T3/es not_active Expired - Lifetime
- 1995-08-07 RU RU97103951/04A patent/RU2150472C1/ru not_active IP Right Cessation
-
1996
- 1996-01-16 US US08/586,037 patent/US5693816A/en not_active Expired - Lifetime
-
1997
- 1997-02-10 FI FI970564A patent/FI120347B/fi not_active IP Right Cessation
-
1999
- 1999-06-28 CN CN99108855A patent/CN1122039C/zh not_active Expired - Fee Related
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| FG | Patent granted |
Ref document number: 120347 Country of ref document: FI |
|
| PC | Transfer of assignment of patent |
Owner name: MERCK SHARP & DOHME CORP. Free format text: MERCK SHARP & DOHME CORP. |
|
| MM | Patent lapsed |