FI970448L - N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina - Google Patents

N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina Download PDF

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Publication number
FI970448L
FI970448L FI970448A FI970448A FI970448L FI 970448 L FI970448 L FI 970448L FI 970448 A FI970448 A FI 970448A FI 970448 A FI970448 A FI 970448A FI 970448 L FI970448 L FI 970448L
Authority
FI
Finland
Prior art keywords
azobicyclo
neuroleptics
substituted
derivatives useful
heptane derivatives
Prior art date
Application number
FI970448A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI970448A7 (fi
FI970448A0 (fi
Inventor
Gerd Steiner
Rainer Munschauer
Thomas Hoeger
Liliane Unger
Hans-Juergen Teschendorf
Original Assignee
Basf Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Basf Ag filed Critical Basf Ag
Publication of FI970448A0 publication Critical patent/FI970448A0/fi
Publication of FI970448A7 publication Critical patent/FI970448A7/fi
Publication of FI970448L publication Critical patent/FI970448L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/06—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing only aliphatic carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/18—Antipsychotics, i.e. neuroleptics; Drugs for mania or schizophrenia
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/20—Hypnotics; Sedatives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/22—Anxiolytics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
    • C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
    • C07D513/04—Ortho-condensed systems

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Biomedical Technology (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI970448A 1994-08-04 1995-07-21 N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina FI970448L (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE4427648A DE4427648A1 (de) 1994-08-04 1994-08-04 N-Stubstituierte 3-Azabicyclo[3,2,0,]heptan-Derivate, ihre Herstellung und Verwendung
PCT/EP1995/002893 WO1996004272A1 (fr) 1994-08-04 1995-07-21 Derives de 3-azabicyclo(3.2.0)heptanes a substitution azote et leur utilisation comme neuroleptiques

Publications (3)

Publication Number Publication Date
FI970448A0 FI970448A0 (fi) 1997-02-03
FI970448A7 FI970448A7 (fi) 1997-04-03
FI970448L true FI970448L (fi) 1997-04-03

Family

ID=6524944

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970448A FI970448L (fi) 1994-08-04 1995-07-21 N-substituoituja 3-atsobisyklo(3.2.0)heptaanijohdannaisia,jotka ovat käyttökelpoisia neuroleptisina aineina

Country Status (25)

Country Link
US (1) US6028073A (fr)
EP (1) EP0775135B1 (fr)
JP (1) JPH10503503A (fr)
CN (1) CN1066145C (fr)
AT (1) ATE242236T1 (fr)
AU (1) AU696230B2 (fr)
BG (1) BG63633B1 (fr)
CA (1) CA2196809A1 (fr)
CZ (1) CZ287862B6 (fr)
DE (2) DE4427648A1 (fr)
DK (1) DK0775135T3 (fr)
ES (1) ES2201111T3 (fr)
FI (1) FI970448L (fr)
HR (1) HRP950438A2 (fr)
HU (1) HUT77772A (fr)
MX (1) MX9700807A (fr)
NO (1) NO312243B1 (fr)
NZ (1) NZ290426A (fr)
PL (1) PL183526B1 (fr)
PT (1) PT775135E (fr)
RU (1) RU2163604C2 (fr)
SI (1) SI9520094B (fr)
UA (1) UA44903C2 (fr)
WO (1) WO1996004272A1 (fr)
ZA (1) ZA956477B (fr)

Families Citing this family (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE19836406A1 (de) 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE19836404A1 (de) * 1998-08-12 2000-02-17 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
US6458821B1 (en) * 1998-08-12 2002-10-01 Abbott Laboratories N-substituted azabicycloheptane derivatives, production and use thereof
DE19848521A1 (de) * 1998-10-21 2000-04-27 Basf Ag Verfahren zur Herstellung von (+)-exo-6-Phenyl-3-azabicyclo-[3.2.0]heptanen
DE19854147A1 (de) * 1998-11-24 2000-05-25 Basf Ag Verwendung von N-substituierten Azabicycloalkan-Derivaten zur Verwendung bei der Bekämpfung der Cocainsucht
JP4754570B2 (ja) * 2004-10-14 2011-08-24 アボット ゲーエムベーハー ウント カンパニー カーゲー ドーパミンｄ３受容体の調節に応答する障害の治療に好適なアザビシクロヘプチル化合物
TW200845977A (en) * 2007-03-30 2008-12-01 Targacept Inc Sub-type selective azabicycloalkane derivatives
AU2014287471C1 (en) 2013-07-10 2019-11-28 Vertex Pharmaceuticals Incorporated Fused piperidine amides as modulators of ion channels
PE20161476A1 (es) * 2014-06-26 2017-01-07 Hoffmann La Roche Derivados de indolin-2-ona o pirrolo-piridin-2-ona
EP3371174B1 (fr) 2015-11-06 2021-03-17 H. Hoffnabb-La Roche Ag Dérivés d'indolin-2-one
JP6857653B2 (ja) 2015-11-06 2021-04-14 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｎｓ及び関連障害の治療において使用するためのインドリン−２−オン誘導体
HUE050083T2 (hu) 2015-11-06 2020-11-30 Hoffmann La Roche Indolin-2-on származékok
JP6857651B2 (ja) 2015-11-06 2021-04-14 エフ．ホフマン−ラ ロシュ アーゲーＦ． Ｈｏｆｆｍａｎｎ−Ｌａ Ｒｏｃｈｅ Ａｋｔｉｅｎｇｅｓｅｌｌｓｃｈａｆｔ Ｃｎｓ疾患の処置に有用なインドリン−２−オン誘導体
CN112010859B (zh) * 2019-05-30 2022-07-19 中国科学院上海药物研究所 一种并环化合物、其制备方法和用途

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE4243287A1 (de) * 1992-06-19 1993-12-23 Basf Ag N-Substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung
DE4341402A1 (de) * 1993-12-04 1995-06-08 Basf Ag N-substituierte Azabicycloheptan-Derivate, ihre Herstellung und Verwendung

Also Published As

Publication number Publication date
BG63633B1 (bg) 2002-07-31
SI9520094A (en) 1997-08-31
AU3116295A (en) 1996-03-04
CN1066145C (zh) 2001-05-23
AU696230B2 (en) 1998-09-03
PT775135E (pt) 2003-10-31
EP0775135A1 (fr) 1997-05-28
RU2163604C2 (ru) 2001-02-27
BG101220A (bg) 1997-08-29
DE4427648A1 (de) 1996-02-08
FI970448A7 (fi) 1997-04-03
PL183526B1 (pl) 2002-06-28
CZ31097A3 (en) 1997-10-15
MX9700807A (es) 1997-05-31
CZ287862B6 (en) 2001-02-14
NZ290426A (en) 1998-02-26
PL318460A1 (en) 1997-06-09
UA44903C2 (uk) 2002-03-15
NO970473L (no) 1997-04-01
HUT77772A (hu) 1998-08-28
NO970473D0 (no) 1997-02-03
ZA956477B (en) 1997-02-03
WO1996004272A1 (fr) 1996-02-15
NO312243B1 (no) 2002-04-15
SI9520094B (sl) 2002-02-28
EP0775135B1 (fr) 2003-06-04
HRP950438A2 (en) 1997-10-31
US6028073A (en) 2000-02-22
FI970448A0 (fi) 1997-02-03
JPH10503503A (ja) 1998-03-31
DE59510713D1 (de) 2003-07-10
CA2196809A1 (fr) 1996-02-15
CN1156454A (zh) 1997-08-06
DK0775135T3 (da) 2003-09-29
ES2201111T3 (es) 2004-03-16
ATE242236T1 (de) 2003-06-15

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