FI970081A - Dinukleosidi-5',5'-pyrofosfaatit - Google Patents

Dinukleosidi-5',5'-pyrofosfaatit Download PDF

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Publication number
FI970081A
FI970081A FI970081A FI970081A FI970081A FI 970081 A FI970081 A FI 970081A FI 970081 A FI970081 A FI 970081A FI 970081 A FI970081 A FI 970081A FI 970081 A FI970081 A FI 970081A
Authority
FI
Finland
Prior art keywords
riboside
dideoxy
pyrophosphates
azido
dinucleoside
Prior art date
Application number
FI970081A
Other languages
English (en)
Swedish (sv)
Other versions
FI970081A0 (fi
Inventor
Flora Antonio De
Umberto Benatti
Marco Giovine
Original Assignee
Lepetit Spa
Univ Degli Studi Genova
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa, Univ Degli Studi Genova filed Critical Lepetit Spa
Publication of FI970081A0 publication Critical patent/FI970081A0/fi
Publication of FI970081A publication Critical patent/FI970081A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H21/00—Compounds containing two or more mononucleotide units having separate phosphate or polyphosphate groups linked by saccharide radicals of nucleoside groups, e.g. nucleic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Genetics & Genomics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Biotechnology (AREA)
  • Engineering & Computer Science (AREA)
  • Virology (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Dental Preparations (AREA)
  • Photoreceptors In Electrophotography (AREA)
  • Adhesives Or Adhesive Processes (AREA)
FI970081A 1994-07-15 1997-01-08 Dinukleosidi-5',5'-pyrofosfaatit FI970081A (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
EP94202059 1994-07-15
PCT/EP1995/002676 WO1996002554A1 (en) 1994-07-15 1995-07-10 Dinucleoside-5',5'-pyrophosphates

Publications (2)

Publication Number Publication Date
FI970081A0 FI970081A0 (fi) 1997-01-08
FI970081A true FI970081A (fi) 1997-01-08

Family

ID=8217039

Family Applications (1)

Application Number Title Priority Date Filing Date
FI970081A FI970081A (fi) 1994-07-15 1997-01-08 Dinukleosidi-5',5'-pyrofosfaatit

Country Status (15)

Country Link
US (2) US6040297A (fi)
EP (1) EP0773951B1 (fi)
JP (1) JPH10502655A (fi)
AT (1) ATE177431T1 (fi)
AU (1) AU688552B2 (fi)
CA (1) CA2195091A1 (fi)
DE (1) DE69508255T2 (fi)
ES (1) ES2129893T3 (fi)
FI (1) FI970081A (fi)
HU (1) HUT76331A (fi)
IL (1) IL114520A0 (fi)
NO (1) NO965483L (fi)
NZ (1) NZ290127A (fi)
WO (1) WO1996002554A1 (fi)
ZA (1) ZA955826B (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE69834392T2 (de) * 1997-02-06 2007-02-08 Inspire Pharmaceuticals, Inc. Dinukleotide und ihre verwendungen
US6818629B2 (en) 1997-02-10 2004-11-16 Inspire Pharmaceuticals, Inc. Pharmaceutical formulation comprising P1-(2'-deoxycytidine 5'-)P4-(uridine 5'-) tetraphosphate
US7078391B2 (en) * 1997-02-10 2006-07-18 Inspire Pharmaceuticals, Inc. Method of treating edematous retinal disorders
US7223744B2 (en) * 1997-02-10 2007-05-29 Inspire Pharmaceuticals, Inc. Pharmaceutical formulation comprising dinucleoside polyphosphates and salts thereof
US6596725B2 (en) 1997-02-10 2003-07-22 Inspire Pharmaceuticals, Inc. Use of certain dinucleotides to stimulate removal of fluid in retinal detachment and retinal edema
AU6551800A (en) * 1999-08-17 2001-03-13 Adani, Alexander Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptasesand viruses
BRPI0003386B8 (pt) * 2000-08-08 2021-05-25 Cristalia Produtos Quim Farmaceuticos Ltda pró-droga homo ou heterodiméricas úteis no tratamento de doenças ou disfunções mediadas por fosfodiesterases; composições farmacêuticas contendo a pró-droga ou seus sais farmacêuticos aceitáveis; processo de obtenção destas pró-drogas
US6867199B2 (en) 2000-08-21 2005-03-15 Inspire Pharmaceuticals, Inc. Dinucleoside polyphosphate compositions and their therapeutic use
US6555675B2 (en) * 2000-08-21 2003-04-29 Inspire Pharmaceuticals, Inc. Dinucleoside polyphosphate compositions and their therapuetic use as purinergic receptor agonists
US7790037B2 (en) * 2003-06-25 2010-09-07 University of Pittsburgh—of the Commonwealth System of Higher Education Separation of compounds using tagging moieties including varying numbers of repeat units
US20230000894A1 (en) * 2019-09-05 2023-01-05 Mitorainbow Therapeutics, Inc. Treating mitochondrial dna depletion disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3321462A (en) * 1963-07-15 1967-05-23 Syntex Corp Process for the preparation of nucleoside polyphosphates
US3506478A (en) * 1968-08-29 1970-04-14 Budd Co Method of balancing a brake drum
US4855304A (en) * 1985-01-10 1989-08-08 Repligen Corporation Dinucleoside pyrophosphates and pyrophosphate homologs as plant antivirals
US5159067A (en) * 1987-01-28 1992-10-27 University Of Georgia Research Foundation Inc. 5'-Diphosphohexose nucleoside pharmaceutical compositions
CA1330794C (en) * 1987-03-27 1994-07-19 Phillip Frost Anti-viral compounds, dosage forms and methods
IL86650A0 (en) * 1987-06-30 1988-11-30 Biophor Corp Animal derived cells and liposomes,having an antigenic protein incorporated into their membrane
EP0375183A1 (en) * 1988-12-05 1990-06-27 Schering Corporation Antiviral dimers and trimers
NZ233197A (en) * 1989-04-13 1991-11-26 Richard Thomas Walker Aromatically substituted nucleotide derivatives, intermediates therefor and pharmaceutical compositions
ATE157879T1 (de) * 1991-06-14 1997-09-15 Europ Communities Transformierte erythrozyten, verfahren zu deren herstellung, und ihre verwendung in pharmazeutischen zusammensetzungen
US5521161A (en) * 1993-12-20 1996-05-28 Compagnie De Developpment Aguettant S.A. Method of treating HIV in humans by administration of ddI and hydroxycarbamide

Also Published As

Publication number Publication date
FI970081A0 (fi) 1997-01-08
EP0773951A1 (en) 1997-05-21
ZA955826B (en) 1996-02-21
AU3076695A (en) 1996-02-16
IL114520A0 (en) 1995-11-27
US6040297A (en) 2000-03-21
ES2129893T3 (es) 1999-06-16
NO965483D0 (no) 1996-12-19
CA2195091A1 (en) 1996-02-01
HUT76331A (en) 1997-08-28
JPH10502655A (ja) 1998-03-10
MX9700360A (es) 1998-03-31
DE69508255T2 (de) 1999-10-14
US6080731A (en) 2000-06-27
DE69508255D1 (de) 1999-04-15
EP0773951B1 (en) 1999-03-10
NZ290127A (en) 1998-05-27
HU9700118D0 (en) 1997-02-28
ATE177431T1 (de) 1999-03-15
AU688552B2 (en) 1998-03-12
WO1996002554A1 (en) 1996-02-01
NO965483L (no) 1997-01-28

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