ES2159054T3 - Compuestos di-terc-butil-fenolicos que contienen azufre utiles como agentes antiinflamatorios. - Google Patents

Compuestos di-terc-butil-fenolicos que contienen azufre utiles como agentes antiinflamatorios.

Info

Publication number
ES2159054T3
ES2159054T3 ES96939627T ES96939627T ES2159054T3 ES 2159054 T3 ES2159054 T3 ES 2159054T3 ES 96939627 T ES96939627 T ES 96939627T ES 96939627 T ES96939627 T ES 96939627T ES 2159054 T3 ES2159054 T3 ES 2159054T3
Authority
ES
Spain
Prior art keywords
butil
terc
compounds containing
inflammatory agents
phenolic compounds
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired - Lifetime
Application number
ES96939627T
Other languages
English (en)
Inventor
Randall Stryker Matthews
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Procter and Gamble Co
Original Assignee
Procter and Gamble Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Procter and Gamble Co filed Critical Procter and Gamble Co
Application granted granted Critical
Publication of ES2159054T3 publication Critical patent/ES2159054T3/es
Anticipated expiration legal-status Critical
Expired - Lifetime legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C317/00—Sulfones; Sulfoxides
    • C07C317/24—Sulfones; Sulfoxides having sulfone or sulfoxide groups and doubly-bound oxygen atoms bound to the same carbon skeleton
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/12—Ketones
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04—Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/04—Centrally acting analgesics, e.g. opioids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pain & Pain Management (AREA)
  • Biomedical Technology (AREA)
  • Immunology (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Rheumatology (AREA)
  • Epidemiology (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)

Abstract

LA PRESENTE INVENCION SE REFIERE A COMPUESTOS DE ESTRUCTURA (I), DONDE (A) X ES ENTRE 1 Y 5; (B) Y ES ENTRE 1 Y 2, Y (C) Z ES ENTRE 0 Y 5. LA PRESENTE INVENCION SE REFIERE TAMBIEN A LAS COMPOSICIONES FARMACEUTICAS QUE INCLUYEN LOS COMPUESTOS CITADOS, Y A METODOS PARA TRATAR INFLAMACIONES UTILIZANDO LOS COMPUESTOS.
ES96939627T 1995-11-15 1996-11-08 Compuestos di-terc-butil-fenolicos que contienen azufre utiles como agentes antiinflamatorios. Expired - Lifetime ES2159054T3 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/559,014 US5684204A (en) 1995-11-15 1995-11-15 Sulfur containing di-tert-butylphenol compounds useful as anti-inflammatory agents

Publications (1)

Publication Number Publication Date
ES2159054T3 true ES2159054T3 (es) 2001-09-16

Family

ID=24231937

Family Applications (1)

Application Number Title Priority Date Filing Date
ES96939627T Expired - Lifetime ES2159054T3 (es) 1995-11-15 1996-11-08 Compuestos di-terc-butil-fenolicos que contienen azufre utiles como agentes antiinflamatorios.

Country Status (19)

Country Link
US (1) US5684204A (es)
EP (1) EP0863870B1 (es)
JP (1) JP3179501B2 (es)
KR (1) KR100285007B1 (es)
CN (1) CN1078887C (es)
AT (1) ATE202084T1 (es)
AU (1) AU7675896A (es)
BR (1) BR9611472A (es)
CA (1) CA2237558A1 (es)
CZ (1) CZ151698A3 (es)
DE (1) DE69613395T2 (es)
ES (1) ES2159054T3 (es)
HU (1) HUP9902081A3 (es)
IL (1) IL124431A0 (es)
MX (1) MX9803901A (es)
NO (1) NO982229L (es)
NZ (1) NZ322777A (es)
TR (1) TR199800878T2 (es)
WO (1) WO1997018191A1 (es)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP2147679B1 (en) 2001-07-25 2014-06-25 Raptor Pharmaceutical, Inc. Compositions for blood-brain barrier transport
AU2003233670A1 (en) * 2002-05-24 2003-12-12 Pharmacia Corporation Sulfone liver x-receptor modulators
US20050003024A1 (en) * 2003-03-04 2005-01-06 The Procter & Gamble Company Regulation of mammalian hair growth
US20050255059A1 (en) * 2004-05-10 2005-11-17 Oblong John E Personal care compositions and methods regulating mammalian hair growth
US20050255060A1 (en) * 2004-05-10 2005-11-17 Oblong John E Personal care compositions and methods regulating mammalian hair growth
EP2392258B1 (en) 2005-04-28 2014-10-08 Proteus Digital Health, Inc. Pharma-informatics system
US20070203240A1 (en) * 2006-02-27 2007-08-30 The Procter & Gamble Company Personal care compositions and methods for regulating mammalian hair growth
CN101594878A (zh) 2006-09-18 2009-12-02 雷普特药品公司 通过给予受体相关蛋白（rap）-缀合物对肝病症的治疗
PL3395372T3 (pl) 2009-02-20 2022-07-25 EnhanX Biopharm Inc. Układ do dostarczania leków na bazie glutationu
CN102458374A (zh) 2009-05-06 2012-05-16 实验室护肤股份有限公司 包含活性剂-磷酸钙颗粒复合物的皮肤递送组合物及其使用方法
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
JP6302157B2 (ja) * 2012-11-02 2018-03-28 Dic株式会社 ヒンダードフェノールの製造方法

Family Cites Families (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3711544A (en) * 1970-04-20 1973-01-16 Lummus Co Heat recovery in urea synthesis
US3784701A (en) * 1970-09-21 1974-01-08 American Cyanamid Co Compositions containing substituted benzoylpropionic acids and method of use to treat inflammation and pain
US3917672A (en) * 1972-08-17 1975-11-04 Ciba Geigy Corp Hydroxybenzoylalkanoic acid esters
US3862214A (en) * 1973-05-14 1975-01-21 Warner Lambert Co 2-hydroxy-2-(methylsulfonyl)-acetophenone acetates and related compounds
US4130666A (en) * 1977-05-16 1978-12-19 Riker Laboratories, Inc. Anti-inflammatory method
US4172082A (en) * 1977-05-16 1979-10-23 Riker Laboratories, Inc. Substituted thiophenes
US4124725A (en) * 1977-05-16 1978-11-07 Riker Laboratories, Inc. Anti-inflammatory method
US4440784A (en) * 1981-02-05 1984-04-03 Kanegafuchi Chemical Industry Company, Ltd. Anti-inflammatory, analgesic, and antipyretic pharmaceutical composition
US4535165A (en) * 1981-11-23 1985-08-13 Riker Laboratories, Inc. Substituted diazoles and thiazoles
US4418074A (en) * 1981-11-23 1983-11-29 Riker Laboratories, Inc. 2,6 Di(t-butyl)-4-(2'-pyrrol)-phenol and anti-inflammatory use thereof
US4357345A (en) * 1981-11-23 1982-11-02 Riker Laboratories, Inc. Substituted furans
ZA865090B (en) * 1985-07-22 1988-02-24 Riker Laboratories Inc Substituted di-t-butylphenols
US4714776A (en) * 1985-07-22 1987-12-22 Riker Laboratories, Inc. Antiallergic agents
US4677113A (en) * 1986-04-22 1987-06-30 Riker Laboratories, Inc. Di-t-butylphenols substituted by a thenoyl group
US4708966A (en) * 1986-06-27 1987-11-24 The Procter & Gamble Company Novel anti-inflammatory agents, pharmaceutical compositions and methods for reducing inflammation
US4833155A (en) * 1986-11-25 1989-05-23 Syntex (U.S.A.) Inc. 3-(ω-(3,5,-di-t-butyl-4-hydroxyphenyl)-alkanoyl)pyrroles, and anti-inflammatory uses thereof
US4968710A (en) * 1987-11-13 1990-11-06 Riker Laboratories, Inc. Substituted di-t-butylphenols and anti-allergic use thereof
US4982006A (en) * 1987-12-18 1991-01-01 Norwich Eaton Pharmaceuticals, Inc. Process for the preparation of certain substituted aromatic compounds
US5086064A (en) * 1990-03-27 1992-02-04 Warner-Lambert Company 3,5-di-tertiary-butyl-4-hydroxyphenyl thiazolyl, oxazolyl, and imidazolyl methanones and related compounds as antiinflammatory agents
US5102897A (en) * 1990-03-27 1992-04-07 Warner-Lambert Company 3,5-ditertiarybutyl-4-hydroxyphenyl, 1,3,4-thiadiazoles and oxadiazoles linked by carbon, oxygen, and sulfur residues
US5280045A (en) * 1991-10-16 1994-01-18 The Procter & Gamble Company 4(3,5-bis(1,1-dimethylethyl-4-hydroxyphenyl)-4-oxobutanamide compound useful as an anti-inflammatory agent

Also Published As

Publication number Publication date
NZ322777A (en) 2000-03-27
TR199800878T2 (xx) 1998-08-21
US5684204A (en) 1997-11-04
ATE202084T1 (de) 2001-06-15
KR19990067642A (ko) 1999-08-25
CN1202151A (zh) 1998-12-16
CN1078887C (zh) 2002-02-06
IL124431A0 (en) 1998-12-06
EP0863870B1 (en) 2001-06-13
JPH11501664A (ja) 1999-02-09
HUP9902081A2 (hu) 1999-10-28
AU7675896A (en) 1997-06-05
MX9803901A (es) 1998-09-30
DE69613395D1 (de) 2001-07-19
NO982229L (no) 1998-07-15
KR100285007B1 (ko) 2001-04-02
BR9611472A (pt) 1999-02-02
DE69613395T2 (de) 2002-02-07
CA2237558A1 (en) 1997-05-22
JP3179501B2 (ja) 2001-06-25
CZ151698A3 (cs) 1998-10-14
HUP9902081A3 (en) 2001-10-29
EP0863870A1 (en) 1998-09-16
WO1997018191A1 (en) 1997-05-22
NO982229D0 (no) 1998-05-15

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