AU6551800A - Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptasesand viruses - Google Patents

Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptasesand viruses

Info

Publication number
AU6551800A
AU6551800A AU65518/00A AU6551800A AU6551800A AU 6551800 A AU6551800 A AU 6551800A AU 65518/00 A AU65518/00 A AU 65518/00A AU 6551800 A AU6551800 A AU 6551800A AU 6551800 A AU6551800 A AU 6551800A
Authority
AU
Australia
Prior art keywords
transcriptasesand
tetraphosphates
dinucleoside
viruses
inhibitors
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Abandoned
Application number
AU65518/00A
Inventor
Ludmila A. Alexandrova
Anatasiya L. Khandazhynskaya
Alexander A Krayevsky
Arsen M. Murabuldayev
Elena A. Shirokova
Alexander Y. Skoblov
Lyubov S. Victorova
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Individual
Original Assignee
Individual
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Individual filed Critical Individual
Publication of AU6551800A publication Critical patent/AU6551800A/en
Abandoned legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/06—Pyrimidine radicals
    • C07H19/10—Pyrimidine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07H—SUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H19/00—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof
    • C07H19/02—Compounds containing a hetero ring sharing one ring hetero atom with a saccharide radical; Nucleosides; Mononucleotides; Anhydro-derivatives thereof sharing nitrogen
    • C07H19/04—Heterocyclic radicals containing only nitrogen atoms as ring hetero atom
    • C07H19/16—Purine radicals
    • C07H19/20—Purine radicals with the saccharide radical esterified by phosphoric or polyphosphoric acids

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Organic Chemistry (AREA)
  • Molecular Biology (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Virology (AREA)
  • Biochemistry (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Oncology (AREA)
  • Communicable Diseases (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • AIDS & HIV (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
AU65518/00A 1999-08-17 2000-08-17 Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptasesand viruses Abandoned AU6551800A (en)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
US14922399P 1999-08-17 1999-08-17
US60149223 1999-08-17
PCT/CA2000/000929 WO2001012644A1 (en) 1999-08-17 2000-08-17 Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptases and viruses

Publications (1)

Publication Number Publication Date
AU6551800A true AU6551800A (en) 2001-03-13

Family

ID=22529299

Family Applications (1)

Application Number Title Priority Date Filing Date
AU65518/00A Abandoned AU6551800A (en) 1999-08-17 2000-08-17 Dinucleoside 5',5'-tetraphosphates as inhibitors of viral reverse transcriptasesand viruses

Country Status (2)

Country Link
AU (1) AU6551800A (en)
WO (1) WO2001012644A1 (en)

Families Citing this family (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
WO2004090848A1 (en) * 2003-04-02 2004-10-21 Matsushita Electric Industrial Co., Ltd. Method of manufacturing plasma display device
WO2006133375A2 (en) * 2005-06-08 2006-12-14 The University Of Miami Dinucleoside polyphosphate inhibitors of reverse transcriptase
ES2278519B1 (en) * 2005-09-02 2008-09-16 Fundacion Magar Dinucleotides for treatment of achondroplasia, reduce presence of mutated receptor in chondrocytes that shows decrease of pathological effects
WO2008143846A1 (en) * 2007-05-14 2008-11-27 Rfs Pharma, Llc Azido purine nucleosides for treatment of viral infections
US8815829B2 (en) 2008-12-09 2014-08-26 Rfs Pharma, Llc 3′-azido purine nucleotide prodrugs for treatment of viral infections
EP2393815A4 (en) 2009-02-06 2012-11-21 Rfs Pharma Llc Purine nucleoside monophosphate prodrugs for treatment of cancer and viral infections

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CA1330794C (en) * 1987-03-27 1994-07-19 Phillip Frost Anti-viral compounds, dosage forms and methods
WO1990006319A1 (en) * 1988-12-05 1990-06-14 Schering Corporation Antiviral dimers and trimers
NZ233197A (en) * 1989-04-13 1991-11-26 Richard Thomas Walker Aromatically substituted nucleotide derivatives, intermediates therefor and pharmaceutical compositions
ES2129893T3 (en) * 1994-07-15 1999-06-16 Biosearch Italia Spa DINUCLEOSIDE-5 ', 5'-PYROPHOSPHATES.
US5681823A (en) * 1996-05-02 1997-10-28 Prp Inc. P1, P4 -dithio-P2 -P3 -monochloromethylene 5', 5'"-diadenosine P1, P4 -tetraphosphate as antithrombotic agent
WO1998034942A2 (en) * 1997-02-06 1998-08-13 Inspire Pharmaceuticals, Inc. Dinucleotides and their use

Also Published As

Publication number Publication date
WO2001012644A1 (en) 2001-02-22

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Legal Events

Date Code Title Description
MK6 Application lapsed section 142(2)(f)/reg. 8.3(3) - pct applic. not entering national phase