FI965032A0 - Interleukin-5-specifika antikroppar - Google Patents

Interleukin-5-specifika antikroppar

Info

Publication number
FI965032A0
FI965032A0 FI965032A FI965032A FI965032A0 FI 965032 A0 FI965032 A0 FI 965032A0 FI 965032 A FI965032 A FI 965032A FI 965032 A FI965032 A FI 965032A FI 965032 A0 FI965032 A0 FI 965032A0
Authority
FI
Finland
Prior art keywords
interleukin
specific antibodies
heavy
light chain
effective anti
Prior art date
Application number
FI965032A
Other languages
English (en)
Finnish (fi)
Other versions
FI965032A (sv
Inventor
John Spencer Emtage
Mark William Bodmer
Diljeet Singh Anthwal
Original Assignee
Celltech Therapeutics Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Celltech Therapeutics Ltd filed Critical Celltech Therapeutics Ltd
Publication of FI965032A publication Critical patent/FI965032A/sv
Publication of FI965032A0 publication Critical patent/FI965032A0/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K16/00—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/18—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans
    • C07K16/24—Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against material from animals or humans against cytokines, lymphokines or interferons
    • C07K16/244—Interleukins [IL]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P7/00—Drugs for disorders of the blood or the extracellular fluid
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K2319/00—Fusion polypeptide
FI965032A 1994-06-17 1996-12-16 Interleukin-5-specifika antikroppar FI965032A0 (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB9412230A GB9412230D0 (en) 1994-06-17 1994-06-17 Interleukin-5 specific recombiant antibodies
PCT/GB1995/001411 WO1995035375A1 (en) 1994-06-17 1995-06-16 Interleukin-5 specific recombinant antibodies

Publications (2)

Publication Number Publication Date
FI965032A FI965032A (sv) 1996-12-16
FI965032A0 true FI965032A0 (sv) 1996-12-16

Family

ID=10756925

Family Applications (1)

Application Number Title Priority Date Filing Date
FI965032A FI965032A0 (sv) 1994-06-17 1996-12-16 Interleukin-5-specifika antikroppar

Country Status (18)

Country Link
US (3) US5998586A (sv)
EP (1) EP0765392B1 (sv)
JP (1) JP3973682B2 (sv)
AT (1) ATE264389T1 (sv)
AU (1) AU694783B2 (sv)
CA (1) CA2192543C (sv)
CZ (1) CZ292295B6 (sv)
DE (1) DE69532889T2 (sv)
ES (1) ES2218546T3 (sv)
FI (1) FI965032A0 (sv)
GB (1) GB9412230D0 (sv)
HU (1) HU221641B1 (sv)
IL (1) IL114179A (sv)
NO (1) NO964808L (sv)
NZ (1) NZ287927A (sv)
SK (1) SK282625B6 (sv)
WO (1) WO1995035375A1 (sv)
ZA (1) ZA954990B (sv)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
USRE39548E1 (en) 1994-06-17 2007-04-03 Celltech R&D Limited Interleukin-5 specific recombinant antibodies
GB9412230D0 (en) * 1994-06-17 1994-08-10 Celltech Ltd Interleukin-5 specific recombiant antibodies
US5693323A (en) * 1994-12-23 1997-12-02 Smithkline Beecham Corporation Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
CZ297045B6 (cs) * 1994-12-23 2006-08-16 Smithkline Beecham Corporation Hlodavcí neutralizacní monoklonální protilátka, zpusob pro její produkci, kompozice s jejím obsahema pouzití, hybridom a jím produkovaná protilátka,fab fragment, komplementaritu urcující region, molekula nukleové kyseliny a její sekvence, plasmid a
US7399837B2 (en) 1995-12-22 2008-07-15 Smithkline Beecham Corporation Recombinant IL-5 antagonists useful in treatment of IL-5 mediated disorders
CA2370391A1 (en) 1999-04-23 2000-11-02 Pharmexa A/S Method for down-regulating il5 activity
NZ572565A (en) 2006-05-25 2011-04-29 Glaxo Group Ltd Modified humanised anti-interleukin-18 antibodies
BRPI0910854A2 (pt) 2008-03-28 2015-10-06 Glaxosmithkline Llc métodos de tratamento
EP2337801A4 (en) 2008-10-06 2012-07-25 Minerva Biotechnologies Corp MUC1 ANTIBODIES *
EP2600901B1 (en) 2010-08-06 2019-03-27 ModernaTX, Inc. A pharmaceutical formulation comprising engineered nucleic acids and medical use thereof
ES2737960T3 (es) 2010-10-01 2020-01-17 Modernatx Inc Nucleósidos, nucleótidos y ácidos nucleicos modificados y sus usos
WO2012083370A1 (en) * 2010-12-22 2012-06-28 Cephalon Australia Pty Ltd Modified antibody with improved half-life
AU2012236099A1 (en) 2011-03-31 2013-10-03 Moderna Therapeutics, Inc. Delivery and formulation of engineered nucleic acids
US9464124B2 (en) 2011-09-12 2016-10-11 Moderna Therapeutics, Inc. Engineered nucleic acids and methods of use thereof
EP3682905B1 (en) 2011-10-03 2021-12-01 ModernaTX, Inc. Modified nucleosides, nucleotides, and nucleic acids, and uses thereof
EP2791160B1 (en) 2011-12-16 2022-03-02 ModernaTX, Inc. Modified mrna compositions
AU2013243948A1 (en) 2012-04-02 2014-10-30 Moderna Therapeutics, Inc. Modified polynucleotides for the production of proteins associated with human disease
US9303079B2 (en) 2012-04-02 2016-04-05 Moderna Therapeutics, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9572897B2 (en) 2012-04-02 2017-02-21 Modernatx, Inc. Modified polynucleotides for the production of cytoplasmic and cytoskeletal proteins
US9283287B2 (en) 2012-04-02 2016-03-15 Moderna Therapeutics, Inc. Modified polynucleotides for the production of nuclear proteins
EP4074834A1 (en) 2012-11-26 2022-10-19 ModernaTX, Inc. Terminally modified rna
JP6502856B2 (ja) * 2012-12-26 2019-04-17 オンコシナジー インコーポレイテッド 抗インテグリンβ１抗体組成物及びその使用方法
US8980864B2 (en) 2013-03-15 2015-03-17 Moderna Therapeutics, Inc. Compositions and methods of altering cholesterol levels
WO2015048744A2 (en) 2013-09-30 2015-04-02 Moderna Therapeutics, Inc. Polynucleotides encoding immune modulating polypeptides
CA2926218A1 (en) 2013-10-03 2015-04-09 Moderna Therapeutics, Inc. Polynucleotides encoding low density lipoprotein receptor
EP3160479A4 (en) 2014-06-30 2018-07-04 Academia Sinica Antagonists for interleukin-17 receptor b (il-17rb) and its ligand il-17b for cancer therapy
CN107660213B (zh) 2015-02-10 2023-01-13 米纳瓦生物技术公司 人源化抗MUCl＊抗体
BR112018003741A2 (pt) 2015-08-24 2018-09-25 Glaxosmithkline Ip No 2 Ltd composições biofarmacêuticas
WO2018226339A1 (en) 2017-06-06 2018-12-13 Glaxosmithkline Llc Biopharmaceutical compositions and methods for pediatric patients
JP7307720B2 (ja) 2017-09-29 2023-07-12 江蘇恒瑞医薬股▲ふん▼有限公司 Ｉｌ－５抗体、その抗原結合フラグメント、およびそれらの医薬適用
CN109942706A (zh) * 2017-12-21 2019-06-28 三生国健药业（上海）股份有限公司 结合人il-5的单克隆抗体、其制备方法和用途
WO2020119728A1 (zh) * 2018-12-12 2020-06-18 尚华科创投资管理（江苏）有限公司 抗人白细胞介素5(il-5)单克隆抗体及其应用
CN113507938B (zh) 2019-03-29 2024-04-16 广东恒瑞医药有限公司 包含抗il-5抗体的药物组合物及其用途

Family Cites Families (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB8308235D0 (en) * 1983-03-25 1983-05-05 Celltech Ltd Polypeptides
US4816567A (en) * 1983-04-08 1989-03-28 Genentech, Inc. Recombinant immunoglobin preparations
GB8607679D0 (en) * 1986-03-27 1986-04-30 Winter G P Recombinant dna product
IL92180A (en) * 1988-11-03 1997-04-15 Schering Corp Pharmaceutical composition for preventing or reducing eosinophilia
IL162181A (en) * 1988-12-28 2006-04-10 Pdl Biopharma Inc A method of producing humanized immunoglubulin, and polynucleotides encoding the same
US5530101A (en) * 1988-12-28 1996-06-25 Protein Design Labs, Inc. Humanized immunoglobulins
GB8928874D0 (en) * 1989-12-21 1990-02-28 Celltech Ltd Humanised antibodies
AU8910891A (en) * 1990-11-20 1992-06-11 National Heart & Lung Institute, The Treatment of lung diseases
CZ291039B6 (cs) * 1992-02-06 2002-12-11 Schering Corporation Monoklonální protilátka, hybridom, polypeptid a způsob jeho přípravy, izolovaná DNA, rekombinantní vektor, hostitelská buňka, humanizovaná protilátka a farmaceutický prostředek
SG52215A1 (en) * 1992-02-19 1998-09-28 Schering Corp Cloning and expresssion of humanized monoclonal antibodies against human interleukin-4
GB9412230D0 (en) * 1994-06-17 1994-08-10 Celltech Ltd Interleukin-5 specific recombiant antibodies

Also Published As

Publication number Publication date
US6316227B1 (en) 2001-11-13
US6734286B2 (en) 2004-05-11
NZ287927A (en) 1998-07-28
WO1995035375A1 (en) 1995-12-28
CZ292295B6 (cs) 2003-08-13
AU2680395A (en) 1996-01-15
ZA954990B (en) 1996-12-17
GB9412230D0 (en) 1994-08-10
ATE264389T1 (de) 2004-04-15
IL114179A (en) 2001-08-26
US5998586A (en) 1999-12-07
JP3973682B2 (ja) 2007-09-12
NO964808L (no) 1997-02-17
SK160096A3 (en) 1997-06-04
DE69532889D1 (de) 2004-05-19
CA2192543C (en) 2008-07-29
EP0765392A1 (en) 1997-04-02
SK282625B6 (sk) 2002-10-08
AU694783B2 (en) 1998-07-30
CA2192543A1 (en) 1995-12-28
IL114179A0 (en) 1995-10-31
CZ371296A3 (cs) 1998-05-13
FI965032A (sv) 1996-12-16
HU9603183D0 (en) 1997-01-28
ES2218546T3 (es) 2004-11-16
HU221641B1 (hu) 2002-12-28
HUT76672A (en) 1997-10-28
NO964808D0 (no) 1996-11-13
EP0765392B1 (en) 2004-04-14
DE69532889T2 (de) 2005-03-10
US20020042089A1 (en) 2002-04-11
JPH10501697A (ja) 1998-02-17

Similar Documents

Publication Publication Date Title
DE69532889D1 (de) Interleukin-5-spezifische rekombinante antikörper
FI956112A0 (sv) Monoklonal anti- V-integrinantikropp
NO962346D0 (no) Humaniserte antistoffer og anvendelser derav
DK145493D0 (da) Antistof
PT778891E (pt) Anticorpo monoclonal recombinante anti-rhesus d (d7c2)
DE68914244D1 (de) Monoklonaler Antikörper.
AU628948B2 (en) Monoclonal antibodies (mabs) against tumor-associated antigens, the preparation and use thereof
DE69738312D1 (de) Hepatitis b monoklonale antikörper
TR199800517A3 (tr) Hümanize anti-hümen fas antikor.
BR9509902A (pt) Fragmentos de anticorpos monoclonais apresentando atividade imunosupressante
DE59608073D1 (de) Antikörper gegen ein, einen histidin-anteil aufweisendes fusionspolypeptid
NO890116L (no) Monoklonale antistoffer.
DE69023717T2 (de) Monoklonaler Antikörper.
DE69020315D1 (de) Monoklonaler antikörper gegen c-reaktives protein.
ITRM920223A0 (it) Anticorpi monoclonali anti-idiopici diretti contro anticorpi anti-tnf.
NO985281D0 (no) Monoklonalt antihumant MP52-antistoff
BR1100555B1 (pt) anticorpos monoclonais humanizados.
DE69324928T2 (de) Monoklonaler antikörper
FI960566A (sv) Monoklonal antikropp som identifierar ytantigenen i en interstitiell cell
DE68916088D1 (de) Anti-CPBII-monoklonaler Antikörper.
DE69320192D1 (de) Monoklonaler antikörper gegen den extravillösen trophoblast

Legal Events

Date Code Title Description
FD Application lapsed

Free format text: ABB OY