FI952204A0 - Terapeuttisia aineita - Google Patents

Terapeuttisia aineita

Info

Publication number
FI952204A0
FI952204A0 FI952204A FI952204A FI952204A0 FI 952204 A0 FI952204 A0 FI 952204A0 FI 952204 A FI952204 A FI 952204A FI 952204 A FI952204 A FI 952204A FI 952204 A0 FI952204 A0 FI 952204A0
Authority
FI
Finland
Prior art keywords
alkyl
optionally substituted
halo
phenyl
alkoxy
Prior art date
Application number
FI952204A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI952204A (fi
Inventor
John Rosindale Housley
James Edward Jeffery
Kenneth John Nichol
Bruce Jeremy Sargent
Original Assignee
Boots Co Plc
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB929223443A external-priority patent/GB9223443D0/en
Priority claimed from GB929223441A external-priority patent/GB9223441D0/en
Application filed by Boots Co Plc filed Critical Boots Co Plc
Publication of FI952204A publication Critical patent/FI952204A/fi
Publication of FI952204A0 publication Critical patent/FI952204A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/08—Antiepileptics; Anticonvulsants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Neurosurgery (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Neurology (AREA)
  • Public Health (AREA)
  • General Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Psychiatry (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Steroid Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
FI952204A 1992-11-09 1995-05-08 Terapeuttisia aineita FI952204A0 (fi)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
GB929223443A GB9223443D0 (en) 1992-11-09 1992-11-09 Therapeutic agents
GB929223441A GB9223441D0 (en) 1992-11-09 1992-11-09 Therapeutic agents
PCT/EP1993/003123 WO1994011360A1 (en) 1992-11-09 1993-11-06 1,4-benzothiazepines useful as neurological agents

Publications (2)

Publication Number Publication Date
FI952204A FI952204A (fi) 1995-05-08
FI952204A0 true FI952204A0 (fi) 1995-05-08

Family

ID=26301938

Family Applications (1)

Application Number Title Priority Date Filing Date
FI952204A FI952204A0 (fi) 1992-11-09 1995-05-08 Terapeuttisia aineita

Country Status (22)

Country Link
US (1) US5580866A (sk)
EP (1) EP0667866B1 (sk)
JP (1) JPH08503202A (sk)
KR (1) KR100313649B1 (sk)
AT (1) ATE163927T1 (sk)
BG (1) BG62519B1 (sk)
BR (1) BR9307387A (sk)
CA (1) CA2148584A1 (sk)
CZ (1) CZ288595B6 (sk)
DE (1) DE69317436T2 (sk)
DK (1) DK0667866T3 (sk)
ES (1) ES2113081T3 (sk)
FI (1) FI952204A0 (sk)
GR (1) GR3026386T3 (sk)
HU (1) HUT71819A (sk)
NO (1) NO304467B1 (sk)
NZ (1) NZ257843A (sk)
PL (1) PL179401B1 (sk)
RU (1) RU2115650C1 (sk)
SK (1) SK280522B6 (sk)
UA (1) UA41342C2 (sk)
WO (1) WO1994011360A1 (sk)

Families Citing this family (26)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5939412A (en) * 1992-06-26 1999-08-17 Smithkline Beecham Corporation Bicyclic fibrinogen antagonists
ATE228115T1 (de) * 1991-06-28 2002-12-15 Smithkline Beecham Corp Bizyklische fibrinogenantagonisten
MA23420A1 (fr) * 1994-01-07 1995-10-01 Smithkline Beecham Corp Antagonistes bicycliques de fibrinogene.
US6458784B1 (en) 1994-06-29 2002-10-01 Smithkline Beecham Corporation Vitronectin receptor antagonists
GB9506382D0 (en) * 1995-03-29 1995-05-17 Boots Co Plc Pharmaceutical compositions
US5977101A (en) * 1995-06-29 1999-11-02 Smithkline Beecham Corporation Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity
ZA9610853B (en) 1995-12-29 1998-04-06 Smithkline Beecham Corp Processes and intermediates for preparing pharmaceuticals.
GB9616279D0 (en) * 1996-08-02 1996-09-11 Knoll Ag Chemical process
DK0864582T3 (da) * 1997-03-14 2003-09-29 Aventis Pharma Gmbh Hypolidemiske 1,4-benzothiazepin-1,1-dioxider
GB9914745D0 (en) * 1999-06-24 1999-08-25 Knoll Ag Therapeutic agents
US8022058B2 (en) 2000-05-10 2011-09-20 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7718644B2 (en) * 2004-01-22 2010-05-18 The Trustees Of Columbia University In The City Of New York Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof
US7879840B2 (en) 2005-08-25 2011-02-01 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
US7393652B2 (en) 2000-05-10 2008-07-01 The Trustees Of Columbia University In The City Of New York Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2)
US20040229781A1 (en) * 2000-05-10 2004-11-18 Marks Andrew Robert Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias
US7544678B2 (en) 2002-11-05 2009-06-09 The Trustees Of Columbia University In The City Of New York Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2)
JP2007525165A (ja) 2003-03-07 2007-09-06 トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク タイプ１ライアノジン受容体に基づく方法
US8710045B2 (en) 2004-01-22 2014-04-29 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the ryanodine receptors
US7704990B2 (en) * 2005-08-25 2010-04-27 The Trustees Of Columbia University In The City Of New York Agents for preventing and treating disorders involving modulation of the RyR receptors
CN101977902B (zh) 2008-03-03 2013-10-30 阿姆格药物公司 由γ-氨基烷基苯制备苯并硫氮杂*的方法
WO2013064231A1 (en) 2011-10-31 2013-05-10 Phenex Pharmaceuticals Ag SEVEN-MEMBERED SULFONAMIDES AS MODULATORS OF RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORγ, NR1F3)
EP2708535A1 (en) * 2012-05-11 2014-03-19 Les Laboratoires Servier Agents for treating disorders involving modulation of ryanodine receptors
KR102157141B1 (ko) 2018-11-27 2020-09-17 주식회사 파미니티 으아리 추출물을 유효 성분으로 포함하는 인지 기능 개선용 조성물
KR102172916B1 (ko) 2018-12-07 2020-11-02 주식회사 파미니티 실크 펩타이드 및 천연 추출물을 포함하는 인지 기능 개선용 조성물
JP2023549583A (ja) * 2020-11-17 2023-11-27 アームゴ・ファーマ・インコーポレーテッド リアノジン受容体関連障害治療用薬剤
CA3177490A1 (en) 2021-01-08 2022-07-14 Armgo Pharma, Inc. Crystalline forms of a ryanodine receptor modulator and uses thereof

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3362962A (en) * 1964-01-24 1968-01-09 Hoffmann La Roche Certain benzothiazepine derivatives
US3682962A (en) * 1970-03-17 1972-08-08 Sterling Drug Inc 1-substituted-1,2,3,5-tetrahydro-4,1-benzothiozepines
DE58901634D1 (de) * 1988-11-05 1992-07-16 Bayer Ag Verfahren zur kernchlorierung von aromatischen kohlenwasserstoffen.
JP2703408B2 (ja) * 1990-12-28 1998-01-26 麒麟麦酒株式会社 １，４‐ベンゾチアゼピン誘導体
GB9111376D0 (en) * 1991-05-25 1991-07-17 Boots Co Plc Therapeutic agents
GB9203347D0 (en) * 1992-02-17 1992-04-01 Wellcome Found Hypolipidaemic compounds

Also Published As

Publication number Publication date
FI952204A (fi) 1995-05-08
UA41342C2 (uk) 2001-09-17
EP0667866A1 (en) 1995-08-23
HU9501352D0 (en) 1995-06-28
GR3026386T3 (en) 1998-06-30
NO304467B1 (no) 1998-12-21
ATE163927T1 (de) 1998-03-15
CZ288595B6 (cs) 2001-07-11
CA2148584A1 (en) 1994-05-26
CZ117695A3 (en) 1996-06-12
AU680639B2 (en) 1997-08-07
WO1994011360A1 (en) 1994-05-26
ES2113081T3 (es) 1998-04-16
EP0667866B1 (en) 1998-03-11
RU95112484A (ru) 1997-04-20
AU5464494A (en) 1994-06-08
DE69317436D1 (de) 1998-04-16
BR9307387A (pt) 1999-08-31
NZ257843A (en) 1996-10-28
NO951797L (no) 1995-05-24
PL179401B1 (pl) 2000-08-31
SK280522B6 (sk) 2000-03-13
KR950704283A (ko) 1995-11-17
NO951797D0 (no) 1995-05-08
JPH08503202A (ja) 1996-04-09
BG99679A (bg) 1996-04-30
KR100313649B1 (ko) 2002-02-28
HUT71819A (en) 1996-02-28
DE69317436T2 (de) 1998-07-02
US5580866A (en) 1996-12-03
BG62519B1 (bg) 2000-01-31
SK58895A3 (en) 1995-09-13
RU2115650C1 (ru) 1998-07-20
PL308757A1 (en) 1995-08-21
DK0667866T3 (da) 1998-05-25

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