FI952204A0 - Terapeuttisia aineita - Google Patents
Terapeuttisia aineitaInfo
- Publication number
- FI952204A0 FI952204A0 FI952204A FI952204A FI952204A0 FI 952204 A0 FI952204 A0 FI 952204A0 FI 952204 A FI952204 A FI 952204A FI 952204 A FI952204 A FI 952204A FI 952204 A0 FI952204 A0 FI 952204A0
- Authority
- FI
- Finland
- Prior art keywords
- alkyl
- optionally substituted
- halo
- phenyl
- alkoxy
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
- C07D281/02—Seven-membered rings
- C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
- C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
- C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/08—Antiepileptics; Anticonvulsants
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P25/00—Drugs for disorders of the nervous system
- A61P25/28—Drugs for disorders of the nervous system for treating neurodegenerative disorders of the central nervous system, e.g. nootropic agents, cognition enhancers, drugs for treating Alzheimer's disease or other forms of dementia
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Neurosurgery (AREA)
- Engineering & Computer Science (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Biomedical Technology (AREA)
- Neurology (AREA)
- Public Health (AREA)
- General Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Veterinary Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Psychiatry (AREA)
- Pain & Pain Management (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Steroid Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
- Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
GB929223443A GB9223443D0 (en) | 1992-11-09 | 1992-11-09 | Therapeutic agents |
GB929223441A GB9223441D0 (en) | 1992-11-09 | 1992-11-09 | Therapeutic agents |
PCT/EP1993/003123 WO1994011360A1 (en) | 1992-11-09 | 1993-11-06 | 1,4-benzothiazepines useful as neurological agents |
Publications (2)
Publication Number | Publication Date |
---|---|
FI952204A FI952204A (fi) | 1995-05-08 |
FI952204A0 true FI952204A0 (fi) | 1995-05-08 |
Family
ID=26301938
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI952204A FI952204A0 (fi) | 1992-11-09 | 1995-05-08 | Terapeuttisia aineita |
Country Status (22)
Country | Link |
---|---|
US (1) | US5580866A (sk) |
EP (1) | EP0667866B1 (sk) |
JP (1) | JPH08503202A (sk) |
KR (1) | KR100313649B1 (sk) |
AT (1) | ATE163927T1 (sk) |
BG (1) | BG62519B1 (sk) |
BR (1) | BR9307387A (sk) |
CA (1) | CA2148584A1 (sk) |
CZ (1) | CZ288595B6 (sk) |
DE (1) | DE69317436T2 (sk) |
DK (1) | DK0667866T3 (sk) |
ES (1) | ES2113081T3 (sk) |
FI (1) | FI952204A0 (sk) |
GR (1) | GR3026386T3 (sk) |
HU (1) | HUT71819A (sk) |
NO (1) | NO304467B1 (sk) |
NZ (1) | NZ257843A (sk) |
PL (1) | PL179401B1 (sk) |
RU (1) | RU2115650C1 (sk) |
SK (1) | SK280522B6 (sk) |
UA (1) | UA41342C2 (sk) |
WO (1) | WO1994011360A1 (sk) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US5939412A (en) * | 1992-06-26 | 1999-08-17 | Smithkline Beecham Corporation | Bicyclic fibrinogen antagonists |
ATE228115T1 (de) * | 1991-06-28 | 2002-12-15 | Smithkline Beecham Corp | Bizyklische fibrinogenantagonisten |
MA23420A1 (fr) * | 1994-01-07 | 1995-10-01 | Smithkline Beecham Corp | Antagonistes bicycliques de fibrinogene. |
US6458784B1 (en) | 1994-06-29 | 2002-10-01 | Smithkline Beecham Corporation | Vitronectin receptor antagonists |
GB9506382D0 (en) * | 1995-03-29 | 1995-05-17 | Boots Co Plc | Pharmaceutical compositions |
US5977101A (en) * | 1995-06-29 | 1999-11-02 | Smithkline Beecham Corporation | Benzimidazoles/Imidazoles Linked to a Fibrinogen Receptor Antagonist Template Having Vitronectin Receptor Antagonist Activity |
ZA9610853B (en) | 1995-12-29 | 1998-04-06 | Smithkline Beecham Corp | Processes and intermediates for preparing pharmaceuticals. |
GB9616279D0 (en) * | 1996-08-02 | 1996-09-11 | Knoll Ag | Chemical process |
DK0864582T3 (da) * | 1997-03-14 | 2003-09-29 | Aventis Pharma Gmbh | Hypolidemiske 1,4-benzothiazepin-1,1-dioxider |
GB9914745D0 (en) * | 1999-06-24 | 1999-08-25 | Knoll Ag | Therapeutic agents |
US8022058B2 (en) | 2000-05-10 | 2011-09-20 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
US7718644B2 (en) * | 2004-01-22 | 2010-05-18 | The Trustees Of Columbia University In The City Of New York | Anti-arrhythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) and uses thereof |
US7879840B2 (en) | 2005-08-25 | 2011-02-01 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
US7393652B2 (en) | 2000-05-10 | 2008-07-01 | The Trustees Of Columbia University In The City Of New York | Methods for identifying a chemical compound that directly enhances binding of FKBP12.6 to PKA-phosphorylated type 2 ryanodine receptor (RyR2) |
US20040229781A1 (en) * | 2000-05-10 | 2004-11-18 | Marks Andrew Robert | Compounds and methods for treating and preventing exercise-induced cardiac arrhythmias |
US7544678B2 (en) | 2002-11-05 | 2009-06-09 | The Trustees Of Columbia University In The City Of New York | Anti-arrythmic and heart failure drugs that target the leak in the ryanodine receptor (RyR2) |
JP2007525165A (ja) | 2003-03-07 | 2007-09-06 | トラスティーズ・オブ・コロンビア・ユニバーシティ・イン・ザ・シティ・オブ・ニューヨーク | タイプ1ライアノジン受容体に基づく方法 |
US8710045B2 (en) | 2004-01-22 | 2014-04-29 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the ryanodine receptors |
US7704990B2 (en) * | 2005-08-25 | 2010-04-27 | The Trustees Of Columbia University In The City Of New York | Agents for preventing and treating disorders involving modulation of the RyR receptors |
CN101977902B (zh) | 2008-03-03 | 2013-10-30 | 阿姆格药物公司 | 由γ-氨基烷基苯制备苯并硫氮杂*的方法 |
WO2013064231A1 (en) | 2011-10-31 | 2013-05-10 | Phenex Pharmaceuticals Ag | SEVEN-MEMBERED SULFONAMIDES AS MODULATORS OF RAR-RELATED ORPHAN RECEPTOR-GAMMA (RORγ, NR1F3) |
EP2708535A1 (en) * | 2012-05-11 | 2014-03-19 | Les Laboratoires Servier | Agents for treating disorders involving modulation of ryanodine receptors |
KR102157141B1 (ko) | 2018-11-27 | 2020-09-17 | 주식회사 파미니티 | 으아리 추출물을 유효 성분으로 포함하는 인지 기능 개선용 조성물 |
KR102172916B1 (ko) | 2018-12-07 | 2020-11-02 | 주식회사 파미니티 | 실크 펩타이드 및 천연 추출물을 포함하는 인지 기능 개선용 조성물 |
JP2023549583A (ja) * | 2020-11-17 | 2023-11-27 | アームゴ・ファーマ・インコーポレーテッド | リアノジン受容体関連障害治療用薬剤 |
CA3177490A1 (en) | 2021-01-08 | 2022-07-14 | Armgo Pharma, Inc. | Crystalline forms of a ryanodine receptor modulator and uses thereof |
Family Cites Families (6)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US3362962A (en) * | 1964-01-24 | 1968-01-09 | Hoffmann La Roche | Certain benzothiazepine derivatives |
US3682962A (en) * | 1970-03-17 | 1972-08-08 | Sterling Drug Inc | 1-substituted-1,2,3,5-tetrahydro-4,1-benzothiozepines |
DE58901634D1 (de) * | 1988-11-05 | 1992-07-16 | Bayer Ag | Verfahren zur kernchlorierung von aromatischen kohlenwasserstoffen. |
JP2703408B2 (ja) * | 1990-12-28 | 1998-01-26 | 麒麟麦酒株式会社 | 1,4‐ベンゾチアゼピン誘導体 |
GB9111376D0 (en) * | 1991-05-25 | 1991-07-17 | Boots Co Plc | Therapeutic agents |
GB9203347D0 (en) * | 1992-02-17 | 1992-04-01 | Wellcome Found | Hypolipidaemic compounds |
-
1993
- 1993-11-06 DE DE69317436T patent/DE69317436T2/de not_active Expired - Fee Related
- 1993-11-06 WO PCT/EP1993/003123 patent/WO1994011360A1/en active IP Right Grant
- 1993-11-06 DK DK94900113.5T patent/DK0667866T3/da active
- 1993-11-06 US US08/424,464 patent/US5580866A/en not_active Expired - Fee Related
- 1993-11-06 EP EP94900113A patent/EP0667866B1/en not_active Expired - Lifetime
- 1993-11-06 HU HU9501352A patent/HUT71819A/hu unknown
- 1993-11-06 ES ES94900113T patent/ES2113081T3/es not_active Expired - Lifetime
- 1993-11-06 KR KR1019950701831A patent/KR100313649B1/ko not_active IP Right Cessation
- 1993-11-06 UA UA95062705A patent/UA41342C2/uk unknown
- 1993-11-06 CZ CZ19951176A patent/CZ288595B6/cs not_active IP Right Cessation
- 1993-11-06 PL PL93308757A patent/PL179401B1/pl unknown
- 1993-11-06 RU RU95112484/04A patent/RU2115650C1/ru not_active IP Right Cessation
- 1993-11-06 BR BR9307387-9A patent/BR9307387A/pt not_active Application Discontinuation
- 1993-11-06 CA CA002148584A patent/CA2148584A1/en not_active Abandoned
- 1993-11-06 JP JP6511695A patent/JPH08503202A/ja not_active Withdrawn
- 1993-11-06 AT AT94900113T patent/ATE163927T1/de not_active IP Right Cessation
- 1993-11-06 SK SK588-95A patent/SK280522B6/sk unknown
- 1993-11-06 NZ NZ257843A patent/NZ257843A/en unknown
-
1995
- 1995-05-08 FI FI952204A patent/FI952204A0/fi unknown
- 1995-05-08 NO NO951797A patent/NO304467B1/no not_active IP Right Cessation
- 1995-05-30 BG BG99679A patent/BG62519B1/bg unknown
-
1998
- 1998-03-17 GR GR980400582T patent/GR3026386T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
FI952204A (fi) | 1995-05-08 |
UA41342C2 (uk) | 2001-09-17 |
EP0667866A1 (en) | 1995-08-23 |
HU9501352D0 (en) | 1995-06-28 |
GR3026386T3 (en) | 1998-06-30 |
NO304467B1 (no) | 1998-12-21 |
ATE163927T1 (de) | 1998-03-15 |
CZ288595B6 (cs) | 2001-07-11 |
CA2148584A1 (en) | 1994-05-26 |
CZ117695A3 (en) | 1996-06-12 |
AU680639B2 (en) | 1997-08-07 |
WO1994011360A1 (en) | 1994-05-26 |
ES2113081T3 (es) | 1998-04-16 |
EP0667866B1 (en) | 1998-03-11 |
RU95112484A (ru) | 1997-04-20 |
AU5464494A (en) | 1994-06-08 |
DE69317436D1 (de) | 1998-04-16 |
BR9307387A (pt) | 1999-08-31 |
NZ257843A (en) | 1996-10-28 |
NO951797L (no) | 1995-05-24 |
PL179401B1 (pl) | 2000-08-31 |
SK280522B6 (sk) | 2000-03-13 |
KR950704283A (ko) | 1995-11-17 |
NO951797D0 (no) | 1995-05-08 |
JPH08503202A (ja) | 1996-04-09 |
BG99679A (bg) | 1996-04-30 |
KR100313649B1 (ko) | 2002-02-28 |
HUT71819A (en) | 1996-02-28 |
DE69317436T2 (de) | 1998-07-02 |
US5580866A (en) | 1996-12-03 |
BG62519B1 (bg) | 2000-01-31 |
SK58895A3 (en) | 1995-09-13 |
RU2115650C1 (ru) | 1998-07-20 |
PL308757A1 (en) | 1995-08-21 |
DK0667866T3 (da) | 1998-05-25 |
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