FI951370A - Tiatsolidinin ja oksatsolidinin johdannaiset, niiden valmistus ja lääkinnällinen käyttö - Google Patents
Tiatsolidinin ja oksatsolidinin johdannaiset, niiden valmistus ja lääkinnällinen käyttö Download PDFInfo
- Publication number
- FI951370A FI951370A FI951370A FI951370A FI951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A
- Authority
- FI
- Finland
- Prior art keywords
- thiazolidine
- preparation
- medical use
- oxazolidine derivatives
- oxazolidine
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
- C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
- C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
- C07D277/32—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D277/34—Oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/14—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
Applications Claiming Priority (1)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP5154194 | 1994-03-23 |
Publications (2)
| Publication Number | Publication Date |
|---|---|
| FI951370A0 FI951370A0 (fi) | 1995-03-23 |
| FI951370A true FI951370A (fi) | 1995-09-24 |
Family
ID=12889893
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI951370A FI951370A (fi) | 1994-03-23 | 1995-03-23 | Tiatsolidinin ja oksatsolidinin johdannaiset, niiden valmistus ja lääkinnällinen käyttö |
Country Status (15)
| Country | Link |
|---|---|
| US (2) | US5578620A (no) |
| EP (1) | EP0678511A3 (no) |
| KR (1) | KR950032187A (no) |
| CN (1) | CN1065532C (no) |
| AU (1) | AU682435B2 (no) |
| CA (1) | CA2145257A1 (no) |
| CZ (1) | CZ283938B6 (no) |
| FI (1) | FI951370A (no) |
| HU (1) | HUT71231A (no) |
| ID (1) | ID23600A (no) |
| IL (1) | IL113084A (no) |
| NO (1) | NO303782B1 (no) |
| NZ (1) | NZ270793A (no) |
| TW (1) | TW363959B (no) |
| ZA (1) | ZA952383B (no) |
Families Citing this family (41)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US5925656A (en) * | 1995-04-10 | 1999-07-20 | Dr. Reddy's Research Foundation | Compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| CZ293016B6 (cs) * | 1995-06-01 | 2004-01-14 | Sankyo Company Limited | Benzimidazolové deriváty a farmaceutické prostředky s jejich obsahem |
| EP0783888A1 (en) | 1995-12-26 | 1997-07-16 | Sankyo Company Limited | Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis |
| ATE231136T1 (de) * | 1996-04-09 | 2003-02-15 | Reddys Lab Ltd Dr | Thiazolidinedionderivate mit antidiabetischen, hypolipidämischen und antihypertensiven eigenschaften, verfahren zu deren herstellung und pharmazeutischen zusammenstellungen, die sie enthalten |
| ZA973850B (en) * | 1996-05-06 | 1997-12-02 | Reddy Research Foundation | Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them. |
| US5889032A (en) * | 1996-05-06 | 1999-03-30 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| US5919782A (en) * | 1996-05-06 | 1999-07-06 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| US5801173A (en) * | 1996-05-06 | 1998-09-01 | Dr. Reddy's Research Foundation | Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| US5885997A (en) * | 1996-07-01 | 1999-03-23 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
| US6372750B2 (en) | 1996-07-01 | 2002-04-16 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases |
| US6114526A (en) * | 1996-07-01 | 2000-09-05 | Dr. Reddy's Research Foundation | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
| CZ298812B6 (cs) * | 1996-07-01 | 2008-02-13 | Dr. Reddy's Laboratories Limited | Azolidindionové deriváty, způsob jejich přípravy, farmaceutické kompozice s jejich obsahem a jejich použití v léčbě diabetu a příbuzných nemocí |
| USRE39266E1 (en) * | 1996-07-01 | 2006-09-05 | Dr. Reddy's Laboratories, Limited | Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases |
| HU225415B1 (en) * | 1996-07-15 | 2006-11-28 | Sankyo Co | Medicinal compositions comprising cs-866 and insulin resistance improving agents and their use for the treatment of arteriosclerosis and xanthoma |
| TW577875B (en) * | 1997-01-31 | 2004-03-01 | Shionogi & Co | Pyrrolidine derivatives with inhibitory activity for phospholipase A2 |
| US6313113B1 (en) | 1997-04-15 | 2001-11-06 | Reddy-Cheminor, Inc. | Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| WO1997041119A1 (en) * | 1997-05-02 | 1997-11-06 | Dr. Reddy's Research Foundation | Novel antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them |
| DE69824756T2 (de) * | 1997-12-02 | 2005-07-14 | Dr. Reddy's Laboratories Ltd. | Substituierte thiazolidinedione und oxazolidinedione mit antidiabetischen,hypolipidämischen und antihypertensiven eigenschaften |
| US6436914B1 (en) | 1998-06-30 | 2002-08-20 | Bristol-Myers Squibb Company | 2-hydroxy-3—(4-hydroxy-3-sulfonamidophenyl)—propylamines useful as beta 3 adrenergic agonists |
| CZ2003106A3 (cs) | 2000-07-13 | 2003-04-16 | Eli Lilly And Company | Agonisté adrenergního beta-3 receptoru |
| US6514991B2 (en) | 2000-07-17 | 2003-02-04 | Wyeth | Phenyl-oxo-tetrahydroquinolin-3-yl beta-3 adrenergic receptor agonists |
| US6465501B2 (en) | 2000-07-17 | 2002-10-15 | Wyeth | Azolidines as β3 adrenergic receptor agonists |
| US6498170B2 (en) | 2000-07-17 | 2002-12-24 | Wyeth | Cyclamine sulfonamides as β-3 adrenergic receptor agonists |
| US6451814B1 (en) | 2000-07-17 | 2002-09-17 | Wyeth | Heterocyclic β-3 adrenergic receptor agonists |
| US6509358B2 (en) | 2000-07-17 | 2003-01-21 | Wyeth | Piperidino-phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists |
| US6525202B2 (en) | 2000-07-17 | 2003-02-25 | Wyeth | Cyclic amine phenyl beta-3 adrenergic receptor agonists |
| US6444685B1 (en) | 2000-07-17 | 2002-09-03 | Wyeth | N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists |
| US6506901B2 (en) | 2000-07-17 | 2003-01-14 | Wyeth | Substituted 2-(S)-hydroxy-3-(piperidin-4-yl-methylamino)-propyl ethers and substituted 2-aryl-2-(R)-hydroxy-1-(piperidin-4-yl-methyl)-ethylamine β-3 adrenergic receptor agonists |
| US6395762B1 (en) | 2000-07-17 | 2002-05-28 | American Home Products Corporation | Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists |
| US6537994B2 (en) | 2000-07-17 | 2003-03-25 | Wyeth | Heterocyclic β3 adrenergic receptor agonists |
| US6458817B1 (en) | 2000-07-17 | 2002-10-01 | Wyeth | Substituted arylsulfides, arylsulfoxides and arylsulfones as beta-3 adrenergic receptor agonists |
| US6410734B1 (en) * | 2000-07-17 | 2002-06-25 | Wyeth | 2-substituted thiazolidinones as beta-3 adrenergic receptor agonists |
| DE60120748T2 (de) | 2000-11-10 | 2007-05-16 | Eli Lilly And Co., Indianapolis | 3-substituierte oxindolderivate als beta-3-agonisten |
| WO2002094820A1 (en) * | 2001-05-23 | 2002-11-28 | Eli Lilly And Company | Crystalline salts of 2-(4-{2-[2-hydroxy-3-(2-thiophen-2-yl-phenoxy)-propylamino]-2-methyl-propyl}-phenoxy)-nicotinonitrile |
| JP2005507872A (ja) | 2001-08-14 | 2005-03-24 | イーライ・リリー・アンド・カンパニー | ３−置換オキシインドールβ３アゴニスト |
| DE60215028T2 (de) | 2001-08-14 | 2007-03-15 | Eli Lilly And Co., Indianapolis | Indol derivate als beta-3-adrenerge agonisten zur behandlung von typ 2 diabetes |
| ES2242890T3 (es) | 2001-11-20 | 2005-11-16 | Eli Lilly And Company | Agonistas beta 3 de oxindol 3-sustituido. |
| WO2003044017A1 (en) | 2001-11-20 | 2003-05-30 | Eli Lilly And Company | Beta 3 adrenergic agonists |
| US7009060B2 (en) | 2002-01-11 | 2006-03-07 | Eli Lilly And Company | 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as β3 agonists |
| WO2006041921A2 (en) * | 2004-10-05 | 2006-04-20 | Auspex Pharmaceuticals, Inc. | Preparation and uses of rhodanine derivatives |
| ES2394349B1 (es) | 2012-08-29 | 2013-11-04 | Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii | Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar |
Family Cites Families (13)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| JPS5522636A (en) * | 1978-08-04 | 1980-02-18 | Takeda Chem Ind Ltd | Thiazoliding derivative |
| CA1262729A (en) * | 1983-10-19 | 1989-11-07 | Leo Alig | Phenoxypropanolamines |
| GB8528633D0 (en) * | 1985-11-21 | 1985-12-24 | Beecham Group Plc | Compounds |
| US4968707A (en) * | 1987-06-10 | 1990-11-06 | Pfizer Inc. | Oxazolidin-2-one derivatives as hypoglycemic agents |
| US5260445A (en) * | 1987-09-04 | 1993-11-09 | Beecham Group P.L.C. | 2,4-thiazolidinediones |
| GB9017218D0 (en) * | 1990-08-06 | 1990-09-19 | Beecham Group Plc | Novel compounds |
| GB9023583D0 (en) * | 1990-10-30 | 1990-12-12 | Beecham Group Plc | Novel compounds |
| GB9023584D0 (en) * | 1990-10-30 | 1990-12-12 | Beecham Group Plc | Novel compounds |
| JP3053490B2 (ja) * | 1991-02-25 | 2000-06-19 | 杏林製薬株式会社 | チアゾリジン−２，４−ジオン誘導体とその塩及び製造法 |
| FR2680512B1 (fr) * | 1991-08-20 | 1995-01-20 | Adir | Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent. |
| NO179246C (no) * | 1991-11-20 | 1996-09-04 | Sankyo Co | Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav |
| DE69326736T2 (de) * | 1992-08-31 | 2000-06-08 | Sankyo Co | Oxazolidin-Derivate mit Antidiabetika und Anti-Fettleibigkeit-Eigenschaften, ihre Herstellung und therapeutische Verwendung |
| JPH072848A (ja) * | 1993-04-23 | 1995-01-06 | Sankyo Co Ltd | モルホリンおよびチオモルホリン誘導体 |
-
1995
- 1995-03-22 IL IL11308495A patent/IL113084A/en not_active IP Right Cessation
- 1995-03-22 NO NO951095A patent/NO303782B1/no not_active IP Right Cessation
- 1995-03-22 CA CA002145257A patent/CA2145257A1/en not_active Abandoned
- 1995-03-22 TW TW084102774A patent/TW363959B/zh active
- 1995-03-23 CZ CZ95739A patent/CZ283938B6/cs unknown
- 1995-03-23 ZA ZA952383A patent/ZA952383B/xx unknown
- 1995-03-23 KR KR1019950006242A patent/KR950032187A/ko not_active Application Discontinuation
- 1995-03-23 EP EP95301922A patent/EP0678511A3/en not_active Withdrawn
- 1995-03-23 HU HU9500849A patent/HUT71231A/hu unknown
- 1995-03-23 FI FI951370A patent/FI951370A/fi unknown
- 1995-03-23 ID IDP990567D patent/ID23600A/id unknown
- 1995-03-23 US US08/410,033 patent/US5578620A/en not_active Expired - Fee Related
- 1995-03-23 AU AU15016/95A patent/AU682435B2/en not_active Ceased
- 1995-03-23 NZ NZ270793A patent/NZ270793A/en unknown
- 1995-03-23 CN CN95104547A patent/CN1065532C/zh not_active Expired - Lifetime
-
1996
- 1996-02-21 US US08/604,702 patent/US5688823A/en not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CA2145257A1 (en) | 1995-09-24 |
| NZ270793A (en) | 1996-02-27 |
| IL113084A0 (en) | 1995-06-29 |
| CN1065532C (zh) | 2001-05-09 |
| NO303782B1 (no) | 1998-08-31 |
| CZ283938B6 (cs) | 1998-07-15 |
| TW363959B (en) | 1999-07-11 |
| ZA952383B (en) | 1995-12-14 |
| NO951095D0 (no) | 1995-03-22 |
| FI951370A0 (fi) | 1995-03-23 |
| EP0678511A3 (en) | 1998-06-10 |
| ID23600A (id) | 1995-11-30 |
| AU682435B2 (en) | 1997-10-02 |
| HU9500849D0 (en) | 1995-05-29 |
| NO951095L (no) | 1995-09-25 |
| CN1132750A (zh) | 1996-10-09 |
| US5688823A (en) | 1997-11-18 |
| CZ73995A3 (en) | 1995-12-13 |
| US5578620A (en) | 1996-11-26 |
| EP0678511A2 (en) | 1995-10-25 |
| IL113084A (en) | 1999-01-26 |
| HUT71231A (en) | 1995-11-28 |
| KR950032187A (ko) | 1995-12-20 |
| AU1501695A (en) | 1995-10-05 |
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