FI951370A - Tiazolidin- och oxazolidinderivat, deras framställning och deras medicinska användning - Google Patents

Tiazolidin- och oxazolidinderivat, deras framställning och deras medicinska användning Download PDF

Info

Publication number
FI951370A
FI951370A FI951370A FI951370A FI951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A FI 951370 A FI951370 A FI 951370A
Authority
FI
Finland
Prior art keywords
thiazolidine
preparation
medical use
oxazolidine derivatives
oxazolidine
Prior art date
Application number
FI951370A
Other languages
English (en)
Finnish (fi)
Other versions
FI951370A0 (sv
Inventor
Takashi Fujita
Takao Yoshioka
Hiroaki Yanagisawa
Hiroaki Fujiwara
Hiroyoshi Horikoshi
Minoru Oguchi
Kunio Wada
Koichi Fujimoto
Original Assignee
Sankyo Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sankyo Co filed Critical Sankyo Co
Publication of FI951370A0 publication Critical patent/FI951370A0/sv
Publication of FI951370A publication Critical patent/FI951370A/sv

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/12Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/32Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D277/34Oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/14Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI951370A 1994-03-23 1995-03-23 Tiazolidin- och oxazolidinderivat, deras framställning och deras medicinska användning FI951370A (sv)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
JP5154194 1994-03-23

Publications (2)

Publication Number Publication Date
FI951370A0 FI951370A0 (sv) 1995-03-23
FI951370A true FI951370A (sv) 1995-09-24

Family

ID=12889893

Family Applications (1)

Application Number Title Priority Date Filing Date
FI951370A FI951370A (sv) 1994-03-23 1995-03-23 Tiazolidin- och oxazolidinderivat, deras framställning och deras medicinska användning

Country Status (15)

Country Link
US (2) US5578620A (sv)
EP (1) EP0678511A3 (sv)
KR (1) KR950032187A (sv)
CN (1) CN1065532C (sv)
AU (1) AU682435B2 (sv)
CA (1) CA2145257A1 (sv)
CZ (1) CZ283938B6 (sv)
FI (1) FI951370A (sv)
HU (1) HUT71231A (sv)
ID (1) ID23600A (sv)
IL (1) IL113084A (sv)
NO (1) NO303782B1 (sv)
NZ (1) NZ270793A (sv)
TW (1) TW363959B (sv)
ZA (1) ZA952383B (sv)

Families Citing this family (41)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5925656A (en) * 1995-04-10 1999-07-20 Dr. Reddy's Research Foundation Compounds having antidiabetic, hypolipidemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
IL118474A (en) * 1995-06-01 2001-08-08 Sankyo Co Benzimideol derivatives and pharmaceutical preparations containing them
EP0783888A1 (en) 1995-12-26 1997-07-16 Sankyo Company Limited Use of troglitazone and related thiazolidinediones in the manufacture of a medicament for the treatment and prophylaxis of osteoporosis
ATE231136T1 (de) * 1996-04-09 2003-02-15 Reddys Lab Ltd Dr Thiazolidinedionderivate mit antidiabetischen, hypolipidämischen und antihypertensiven eigenschaften, verfahren zu deren herstellung und pharmazeutischen zusammenstellungen, die sie enthalten
ZA973850B (en) * 1996-05-06 1997-12-02 Reddy Research Foundation Novel antidiabetic compounds having hypolipidaemic, anti-hypertensive properties, process for their preparation and pharmaceutical compositions containing them.
US5801173A (en) * 1996-05-06 1998-09-01 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5919782A (en) * 1996-05-06 1999-07-06 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US5889032A (en) * 1996-05-06 1999-03-30 Dr. Reddy's Research Foundation Heterocyclic compounds having antidiabetic, hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
US6114526A (en) * 1996-07-01 2000-09-05 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
KR100579765B1 (ko) * 1996-07-01 2006-12-28 닥터 레디스 레보러터리즈 리미티드 신규헤테로고리형화합물의제조방법,이를함유하는약제조성물및당뇨병및이와관련된질병의치료에있어서그의용도
USRE39266E1 (en) * 1996-07-01 2006-09-05 Dr. Reddy's Laboratories, Limited Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US5885997A (en) * 1996-07-01 1999-03-23 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compositions containing them and their use in the treatment of diabetes and related diseases
US6372750B2 (en) 1996-07-01 2002-04-16 Dr. Reddy's Research Foundation Heterocyclic compounds, process for their preparation and pharmaceutical compounds containing them and their use in the treatment of diabetes and related diseases
AU714618B2 (en) * 1996-07-15 2000-01-06 Sankyo Company Limited Medicinal composition
TW577875B (en) * 1997-01-31 2004-03-01 Shionogi & Co Pyrrolidine derivatives with inhibitory activity for phospholipase A2
US6313113B1 (en) 1997-04-15 2001-11-06 Reddy-Cheminor, Inc. Heterocyclic compounds having antidiabetic, hypolipidemic and antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
AU2930797A (en) * 1997-05-02 1997-11-19 Dr. Reddy's Research Foundation Novel antidiabetic compounds having hypolipidaemic, antihypertensive properties, process for their preparation and pharmaceutical compositions containing them
WO1998045291A1 (en) * 1997-12-02 1998-10-15 Dr. Reddy's Research Foundation Substituted thiazolidinedione and oxazolidinedione having antidiabetic, hypolipidemia and antihypertensive properties
US6436914B1 (en) 1998-06-30 2002-08-20 Bristol-Myers Squibb Company 2-hydroxy-3—(4-hydroxy-3-sulfonamidophenyl)—propylamines useful as beta 3 adrenergic agonists
DK1303509T3 (da) 2000-07-13 2013-01-02 Lilly Co Eli Beta3 adrenerge agonister
US6458817B1 (en) 2000-07-17 2002-10-01 Wyeth Substituted arylsulfides, arylsulfoxides and arylsulfones as beta-3 adrenergic receptor agonists
US6514991B2 (en) 2000-07-17 2003-02-04 Wyeth Phenyl-oxo-tetrahydroquinolin-3-yl beta-3 adrenergic receptor agonists
US6444685B1 (en) 2000-07-17 2002-09-03 Wyeth N-(4-sulfonylaryl)Cyclylamine 2-hydroxyethylamines as beta-3 adrenergic receptor agonists
US6410734B1 (en) 2000-07-17 2002-06-25 Wyeth 2-substituted thiazolidinones as beta-3 adrenergic receptor agonists
US6525202B2 (en) * 2000-07-17 2003-02-25 Wyeth Cyclic amine phenyl beta-3 adrenergic receptor agonists
US6506901B2 (en) 2000-07-17 2003-01-14 Wyeth Substituted 2-(S)-hydroxy-3-(piperidin-4-yl-methylamino)-propyl ethers and substituted 2-aryl-2-(R)-hydroxy-1-(piperidin-4-yl-methyl)-ethylamine β-3 adrenergic receptor agonists
US6395762B1 (en) 2000-07-17 2002-05-28 American Home Products Corporation Phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists
US6509358B2 (en) 2000-07-17 2003-01-21 Wyeth Piperidino-phenyl amino squarate and thiadiazole dioxide beta-3 adrenergic receptor agonists
US6451814B1 (en) 2000-07-17 2002-09-17 Wyeth Heterocyclic β-3 adrenergic receptor agonists
US6498170B2 (en) 2000-07-17 2002-12-24 Wyeth Cyclamine sulfonamides as β-3 adrenergic receptor agonists
US6465501B2 (en) 2000-07-17 2002-10-15 Wyeth Azolidines as β3 adrenergic receptor agonists
US6537994B2 (en) 2000-07-17 2003-03-25 Wyeth Heterocyclic β3 adrenergic receptor agonists
DE60120748T2 (de) 2000-11-10 2007-05-16 Eli Lilly And Co., Indianapolis 3-substituierte oxindolderivate als beta-3-agonisten
WO2002094820A1 (en) * 2001-05-23 2002-11-28 Eli Lilly And Company Crystalline salts of 2-(4-{2-[2-hydroxy-3-(2-thiophen-2-yl-phenoxy)-propylamino]-2-methyl-propyl}-phenoxy)-nicotinonitrile
US7208505B2 (en) 2001-08-14 2007-04-24 Eli Lilly And Company β3 adrenergic agonists
JP2005507872A (ja) 2001-08-14 2005-03-24 イーライ・リリー・アンド・カンパニー 3−置換オキシインドールβ3アゴニスト
WO2003044017A1 (en) 2001-11-20 2003-05-30 Eli Lilly And Company Beta 3 adrenergic agonists
AU2002347982A1 (en) 2001-11-20 2003-06-10 Eli Lilly And Company 3-SUBSTITUTED OXINDOLE Beta3 AGONISTS
US7009060B2 (en) 2002-01-11 2006-03-07 Eli Lilly And Company 2-oxo-benzimidazolyl substituted ethanolamine derivatives and their use as β3 agonists
WO2006041921A2 (en) * 2004-10-05 2006-04-20 Auspex Pharmaceuticals, Inc. Preparation and uses of rhodanine derivatives
ES2394349B1 (es) 2012-08-29 2013-11-04 Fundación Centro Nacional De Investigaciones Cardiovasculares Carlos Iii Uso de agonistas selectivos de receptores beta-3 adrenérgicos para el tratamiento de hipertensión pulmonar

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5522636A (en) * 1978-08-04 1980-02-18 Takeda Chem Ind Ltd Thiazoliding derivative
CA1262729A (en) * 1983-10-19 1989-11-07 Leo Alig Phenoxypropanolamines
GB8528633D0 (en) * 1985-11-21 1985-12-24 Beecham Group Plc Compounds
US4968707A (en) * 1987-06-10 1990-11-06 Pfizer Inc. Oxazolidin-2-one derivatives as hypoglycemic agents
US5260445A (en) * 1987-09-04 1993-11-09 Beecham Group P.L.C. 2,4-thiazolidinediones
GB9017218D0 (en) * 1990-08-06 1990-09-19 Beecham Group Plc Novel compounds
GB9023584D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
GB9023583D0 (en) * 1990-10-30 1990-12-12 Beecham Group Plc Novel compounds
JP3053490B2 (ja) * 1991-02-25 2000-06-19 杏林製薬株式会社 チアゾリジン−2,4−ジオン誘導体とその塩及び製造法
FR2680512B1 (fr) * 1991-08-20 1995-01-20 Adir Nouveaux derives de 2,4-thiazolidinedione, leur procede de preparation et les compositions pharmaceutiques qui les contiennent.
NO179246C (no) * 1991-11-20 1996-09-04 Sankyo Co Aromatiske amino-alkoholderivater og mellomprodukter til fremstilling derav
ATE185564T1 (de) * 1992-08-31 1999-10-15 Sankyo Co Oxazolidin-derivate mit antidiabetika und anti- fettleibigkeit-eigenschaften, ihre herstellung und therapeutische verwendung
JPH072848A (ja) * 1993-04-23 1995-01-06 Sankyo Co Ltd モルホリンおよびチオモルホリン誘導体

Also Published As

Publication number Publication date
AU682435B2 (en) 1997-10-02
CN1065532C (zh) 2001-05-09
IL113084A0 (en) 1995-06-29
HU9500849D0 (en) 1995-05-29
FI951370A0 (sv) 1995-03-23
HUT71231A (en) 1995-11-28
KR950032187A (ko) 1995-12-20
CZ283938B6 (cs) 1998-07-15
TW363959B (en) 1999-07-11
EP0678511A3 (en) 1998-06-10
CN1132750A (zh) 1996-10-09
US5688823A (en) 1997-11-18
NO303782B1 (no) 1998-08-31
US5578620A (en) 1996-11-26
ZA952383B (en) 1995-12-14
CZ73995A3 (en) 1995-12-13
IL113084A (en) 1999-01-26
AU1501695A (en) 1995-10-05
EP0678511A2 (en) 1995-10-25
ID23600A (id) 1995-11-30
NO951095D0 (no) 1995-03-22
CA2145257A1 (en) 1995-09-24
NZ270793A (en) 1996-02-27
NO951095L (no) 1995-09-25

Similar Documents

Publication Publication Date Title
FI951370A (sv) Tiazolidin- och oxazolidinderivat, deras framställning och deras medicinska användning
FI955235A (sv) Oxazolidindionderivat, deras framställning och användning
FI955051A (sv) Heterocykliska föreningar och framställning och användning av desamma
FI953479A (sv) 1-arylpyrimidinderivat och farmaceutisk användning av dessa
BR9509774A (pt) Fralda descartável
BR9612678A (pt) Seringa descartável
DE69529780D1 (de) Wegwerfwindel
DE69525077D1 (de) Wegwerf-windel
FI956273A (sv) Optiskt aktivt bensotiepinderivat, dess framställning och användning
FI101382B (sv) Dihydroxipropylsulfoetylcellulosor, framställning och användning av de m
FI955679A (sv) Piperidinderivater, framställning och användning därav
FI961977A0 (sv) N-substituerade azabicykloalkanderivat, deras framställning och användning
EE9900135A (et) N-(2-bensotiasolüül)-1-piperidiinetaanamiini derivaadid, nende valmistamine ja kasutamine raviks
DE69123958D1 (de) Wegwerfwerkzeug und -einsatz
FI956251A0 (sv) 1-oxo-2-(fenylsulfonylamino)-pentylpiperidinderivat, framställning och terapeutisk användning av dessa
FI894323A0 (sv) Antimikrobiell ämneskomposition, förfarande och användning
FI971990A (sv) Oxazolyl- och tiazolyl-imidazo-benso- och tienodiazepiner och deras användning som läkemedel
EE03441B1 (et) 5-naftalen-1-üül-1,3-dioksaani derivaadid, nende valmistamine ja terapeutiline kasutamine
NO953002L (no) Anvendelse av eliprodil og enantiomerer derav for fremstilling av medisinske preparater
DE69517491D1 (de) Wegwerfwindel
EE9900560A (et) 5-naftaleen-1-üül-1,3-dioksaani derivaadid, nende valmistamine ja terapeutiline kasutamine
FI945314A0 (sv) Tetrazolderivat, deras framställning och användning
FI950021A0 (sv) Tienopyrimidinderivat, deras framställning och användning
FI940541A0 (fi) Lyfttransportanordning foer foerflyttning och tvaettning av en roerelsehindrad patient
EE02980B1 (et) Bensimidasooli derivaadid, nende valmistamine ja kasutamine