FI953479A - 1-arylpyrimidinderivat och farmaceutisk användning av dessa - Google Patents
1-arylpyrimidinderivat och farmaceutisk användning av dessa Download PDFInfo
- Publication number
- FI953479A FI953479A FI953479A FI953479A FI953479A FI 953479 A FI953479 A FI 953479A FI 953479 A FI953479 A FI 953479A FI 953479 A FI953479 A FI 953479A FI 953479 A FI953479 A FI 953479A
- Authority
- FI
- Finland
- Prior art keywords
- pharmaceutical use
- arylpyrimidine derivatives
- arylpyrimidine
- derivatives
- pharmaceutical
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D239/00—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings
- C07D239/02—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings
- C07D239/24—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members
- C07D239/28—Heterocyclic compounds containing 1,3-diazine or hydrogenated 1,3-diazine rings not condensed with other rings having three or more double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
- C07D239/46—Two or more oxygen, sulphur or nitrogen atoms
- C07D239/52—Two oxygen atoms
- C07D239/54—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals
- C07D239/545—Two oxygen atoms as doubly bound oxygen atoms or as unsubstituted hydroxy radicals with other hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to ring carbon atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
- C07D473/02—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6
- C07D473/04—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms
- C07D473/06—Heterocyclic compounds containing purine ring systems with oxygen, sulphur, or nitrogen atoms directly attached in positions 2 and 6 two oxygen atoms with radicals containing only hydrogen and carbon atoms, attached in position 1 or 3
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
JP16722294 | 1994-07-19 | ||
JP19421994 | 1994-08-18 |
Publications (2)
Publication Number | Publication Date |
---|---|
FI953479A0 FI953479A0 (sv) | 1995-07-18 |
FI953479A true FI953479A (sv) | 1996-01-20 |
Family
ID=26491330
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI953479A FI953479A (sv) | 1994-07-19 | 1995-07-18 | 1-arylpyrimidinderivat och farmaceutisk användning av dessa |
Country Status (7)
Country | Link |
---|---|
US (1) | US5661153A (sv) |
EP (1) | EP0700908A1 (sv) |
AU (1) | AU681034B2 (sv) |
CA (1) | CA2154293A1 (sv) |
FI (1) | FI953479A (sv) |
NO (1) | NO952854L (sv) |
NZ (1) | NZ272591A (sv) |
Families Citing this family (43)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
US6448235B1 (en) | 1994-07-11 | 2002-09-10 | University Of Virginia Patent Foundation | Method for treating restenosis with A2A adenosine receptor agonists |
US6514949B1 (en) | 1994-07-11 | 2003-02-04 | University Of Virginia Patent Foundation | Method compositions for treating the inflammatory response |
US5821247A (en) * | 1996-09-19 | 1998-10-13 | Japan Energy Corporation | Hydroquinone derivative and pharmaceutical use thereof |
AU6320998A (en) | 1997-02-21 | 1998-09-09 | Bristol-Myers Squibb Company | Benzoic acid derivatives and related compounds as antiarrhythmic agents |
US6117878A (en) * | 1998-02-24 | 2000-09-12 | University Of Virginia | 8-phenyl- or 8-cycloalkyl xanthine antagonists of A2B human adenosine receptors |
AU2645299A (en) * | 1998-11-18 | 2000-06-05 | Elena Alexandrovna Izaxon | 6-(3-carboxymethylphenyl)-aminouracyl having a biological activity |
US6232297B1 (en) | 1999-02-01 | 2001-05-15 | University Of Virginia Patent Foundation | Methods and compositions for treating inflammatory response |
US7427606B2 (en) | 1999-02-01 | 2008-09-23 | University Of Virginia Patent Foundation | Method to reduce inflammatory response in transplanted tissue |
US7378400B2 (en) | 1999-02-01 | 2008-05-27 | University Of Virginia Patent Foundation | Method to reduce an inflammatory response from arthritis |
US6322771B1 (en) | 1999-06-18 | 2001-11-27 | University Of Virginia Patent Foundation | Induction of pharmacological stress with adenosine receptor agonists |
US6670334B2 (en) | 2001-01-05 | 2003-12-30 | University Of Virginia Patent Foundation | Method and compositions for treating the inflammatory response |
SE0102764D0 (sv) | 2001-08-17 | 2001-08-17 | Astrazeneca Ab | Compounds |
CA2460911C (en) | 2001-10-01 | 2011-08-30 | University Of Virginia Patent Foundation | 2-propynyl adenosine analogs having a2a agonist activity and compositions thereof |
CA2488367A1 (en) * | 2002-06-06 | 2003-12-18 | Institute Of Medicinal Molecular Design, Inc. | Antiallergic agents |
EP1541562A4 (en) * | 2002-09-20 | 2006-11-15 | Dainippon Sumitomo Pharma Co | NEW URACIL DERIVATIVES AND THEIR MEDICAL USE |
GB0226930D0 (en) | 2002-11-19 | 2002-12-24 | Astrazeneca Ab | Chemical compounds |
KR20070007103A (ko) * | 2004-02-18 | 2007-01-12 | 아스트라제네카 아베 | 벤즈아미드 유도체 및 이의 글루코키나아제 활성화제로서의용도 |
JP2007523905A (ja) * | 2004-02-18 | 2007-08-23 | アストラゼネカ アクチボラグ | 化合物 |
TW200600086A (en) * | 2004-06-05 | 2006-01-01 | Astrazeneca Ab | Chemical compound |
US7442687B2 (en) | 2004-08-02 | 2008-10-28 | The University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs having A2A agonist activity |
NZ585697A (en) | 2004-08-02 | 2011-12-22 | Univ Virginia Patent Found | 2-propynyl adenosine analogs with modified 5'-ribose groups having A2A agonist activity |
US7576069B2 (en) | 2004-08-02 | 2009-08-18 | University Of Virginia Patent Foundation | 2-polycyclic propynyl adenosine analogs having A2A agonist activity |
CA2581619A1 (en) | 2004-10-16 | 2006-04-20 | Astrazeneca Ab | Process for making phenoxy benzamide compounds |
GB0423043D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
GB0423044D0 (en) * | 2004-10-16 | 2004-11-17 | Astrazeneca Ab | Compounds |
JP2008542247A (ja) * | 2005-05-24 | 2008-11-27 | アストラゼネカ アクチボラグ | グルコキナーゼモジュレーターとしての2−フェニル置換イミダゾール[4,5b]ピリジン/ピラジンおよびプリン誘導体 |
TW200714597A (en) * | 2005-05-27 | 2007-04-16 | Astrazeneca Ab | Chemical compounds |
JP4651714B2 (ja) * | 2005-07-09 | 2011-03-16 | アストラゼネカ アクチボラグ | 糖尿病の治療においてglk活性化剤として使用するためのヘテロアリールベンズアミド誘導体 |
US20080234273A1 (en) * | 2005-07-09 | 2008-09-25 | Mckerrecher Darren | Heteroaryl Benzamide Derivatives for Use as Glk Activators in the Treatment of Diabetes |
JP2009500442A (ja) * | 2005-07-09 | 2009-01-08 | アストラゼネカ アクチボラグ | 2型糖尿病を処置するためのグルコキナーゼのモジュレーターとしての2−ヘテロシクリルオキシベンゾイルアミノヘテロシクリル化合物 |
US9202182B2 (en) * | 2005-08-11 | 2015-12-01 | International Business Machines Corporation | Method and system for analyzing business architecture |
TW200738621A (en) * | 2005-11-28 | 2007-10-16 | Astrazeneca Ab | Chemical process |
WO2007120972A2 (en) | 2006-02-10 | 2007-10-25 | University Of Virginia Patent Foundation | Method to treat sickle cell disease |
US8188063B2 (en) | 2006-06-19 | 2012-05-29 | University Of Virginia Patent Foundation | Use of adenosine A2A modulators to treat spinal cord injury |
TW200825063A (en) * | 2006-10-23 | 2008-06-16 | Astrazeneca Ab | Chemical compounds |
TW200825060A (en) * | 2006-10-26 | 2008-06-16 | Astrazeneca Ab | Chemical compounds |
UY30822A1 (es) * | 2006-12-21 | 2008-07-31 | Astrazeneca Ab | Fnueva forma cristalina de 3-{[5-azetidin-1-ylcabonyl)pyrazin-2-yl]oxy}-5-[1-methylethyloxy]-n-1h-pyrazol-3-ylbenzamida, composiciones conteniéndola, procesos de preparacion y aplicaciones |
US8058259B2 (en) | 2007-12-20 | 2011-11-15 | University Of Virginia Patent Foundation | Substituted 4-{3-[6-amino-9-(3,4-dihydroxy-tetrahydro-furan-2-yl)-9H-purin-2-yl]-prop-2-ynyl}-piperidine-1-carboxylic acid esters as A2AR agonists |
BRPI0917589A2 (pt) | 2008-08-04 | 2015-11-17 | Astrazeneca Ab | composto, composição farmacêutica, uso de um composto, método para tratar doenças, processo, combinação farmacêutica, e, reação de metiloxirano-2-carboxilato (ix) com um álcool roh |
GB0902406D0 (en) * | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Crystalline polymorphic form |
GB0902434D0 (en) * | 2009-02-13 | 2009-04-01 | Astrazeneca Ab | Chemical process |
WO2010116176A1 (en) * | 2009-04-09 | 2010-10-14 | Astrazeneca Ab | Pyrazolo [4, 5-e] pyrimidine derivative and its use to treat diabetes and obesity |
WO2010116177A1 (en) | 2009-04-09 | 2010-10-14 | Astrazeneca Ab | A pyrazolo [4,5-e] pyrimidine derivative and its use to treat diabetes and obesity |
Family Cites Families (11)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPS5251395A (en) * | 1975-10-21 | 1977-04-25 | Yamanouchi Pharmaceut Co Ltd | Preparation of novel pteridine derivaties |
JPS5283800A (en) * | 1976-01-01 | 1977-07-12 | Yamanouchi Pharmaceut Co Ltd | Novel pteridine derivative |
SE416810C (sv) * | 1977-10-14 | 1982-05-11 | Draco Ab | Forfarande for framstellning av xantinderivat med antiallergisk aktivitet |
US4452788A (en) * | 1982-04-21 | 1984-06-05 | Warner-Lambert Company | Substituted 8-phenylxanthines |
FR2531085A1 (fr) * | 1982-07-28 | 1984-02-03 | Adir | Nouveaux derives de la xanthine, leur procede de preparation et les compositions pharmaceutiques les renfermant |
GB8929208D0 (en) * | 1989-12-27 | 1990-02-28 | Almirall Lab | New xanthine derivatives |
IT1240843B (it) * | 1990-05-24 | 1993-12-17 | Malesci Istituto Farmacobiologico | Derivati xantinici 1-7 sostituiti ad attivita' antiasmatica, loro sali fisiologicamente accettabili, loro composizioni farmaceutiche e procedimento per la loro preparazione. |
IL98559A0 (en) * | 1990-06-21 | 1992-07-15 | Schering Corp | Polycyclic guanine derivatives |
GB9020921D0 (en) * | 1990-09-26 | 1990-11-07 | Beecham Group Plc | Novel compounds |
JPH05194424A (ja) | 1991-10-09 | 1993-08-03 | Nikko Kyodo Co Ltd | 新規なピリミジン誘導体及び該誘導体を有効成分とする医薬 |
JPH06135943A (ja) | 1992-09-14 | 1994-05-17 | Japan Energy Corp | 新規なウラシル誘導体及びそれを有効成分とするアレルギー疾患治療薬 |
-
1995
- 1995-06-05 US US08/463,277 patent/US5661153A/en not_active Expired - Fee Related
- 1995-07-17 NZ NZ272591A patent/NZ272591A/en unknown
- 1995-07-18 AU AU25057/95A patent/AU681034B2/en not_active Ceased
- 1995-07-18 NO NO952854A patent/NO952854L/no unknown
- 1995-07-18 CA CA002154293A patent/CA2154293A1/en not_active Abandoned
- 1995-07-18 EP EP95305047A patent/EP0700908A1/en not_active Withdrawn
- 1995-07-18 FI FI953479A patent/FI953479A/sv unknown
Also Published As
Publication number | Publication date |
---|---|
NO952854D0 (no) | 1995-07-18 |
US5661153A (en) | 1997-08-26 |
NO952854L (no) | 1996-01-22 |
NZ272591A (en) | 1997-05-26 |
CA2154293A1 (en) | 1996-01-20 |
AU681034B2 (en) | 1997-08-14 |
AU2505795A (en) | 1996-02-01 |
EP0700908A1 (en) | 1996-03-13 |
FI953479A0 (sv) | 1995-07-18 |
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