FI933136A - Antiallergiska och antiinflammatoriska n-hydroxiureaderivat - Google Patents

Antiallergiska och antiinflammatoriska n-hydroxiureaderivat Download PDF

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Publication number
FI933136A
FI933136A FI933136A FI933136A FI933136A FI 933136 A FI933136 A FI 933136A FI 933136 A FI933136 A FI 933136A FI 933136 A FI933136 A FI 933136A FI 933136 A FI933136 A FI 933136A
Authority
FI
Finland
Prior art keywords
hydroxyure
allergic
inflammatory
derivatives
hydroxyure derivatives
Prior art date
Application number
FI933136A
Other languages
English (en)
Other versions
FI933136A0 (fi
Inventor
Takashi Mano
Rodney William Stevens
Masami Nakane
Original Assignee
Pfizer
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Pfizer filed Critical Pfizer
Publication of FI933136A publication Critical patent/FI933136A/fi
Publication of FI933136A0 publication Critical patent/FI933136A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D263/00—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings
    • C07D263/02—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings
    • C07D263/30—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D263/32—Heterocyclic compounds containing 1,3-oxazole or hydrogenated 1,3-oxazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/08—Antiallergic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D277/00—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22—Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/28—Radicals substituted by nitrogen atoms

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Public Health (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Pulmonology (AREA)
  • Immunology (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
FI933136A 1991-01-09 1993-07-08 Antiallergiska och antiinflammatoriska n-hydroxiureaderivat FI933136A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP3012871A JP2528741B2 (ja) 1991-01-09 1991-01-09 オキサゾ―ル、チアゾ―ルおよびイミダゾ―ル化合物
PCT/US1991/008934 WO1992012141A1 (en) 1991-01-09 1991-12-05 N-hydroxyurea derivatives as antiallergy and antiinflammatory agents

Publications (2)

Publication Number Publication Date
FI933136A true FI933136A (fi) 1993-07-08
FI933136A0 FI933136A0 (fi) 1993-07-08

Family

ID=11817487

Family Applications (1)

Application Number Title Priority Date Filing Date
FI933136A FI933136A0 (fi) 1991-01-09 1993-07-08 Antiallergiska och antiinflammatoriska n-hydroxiureaderivat

Country Status (8)

Country Link
US (1) US5464849A (fi)
EP (1) EP0566593A1 (fi)
JP (1) JP2528741B2 (fi)
CA (1) CA2099565C (fi)
FI (1) FI933136A0 (fi)
IE (1) IE920046A1 (fi)
PT (1) PT99982A (fi)
WO (1) WO1992012141A1 (fi)

Families Citing this family (15)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2699172B1 (fr) * 1992-12-11 1995-01-20 Adir Nouveaux dérivés de 4-méthyl-1,3-oxazole, leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
JP3179286B2 (ja) * 1994-05-19 2001-06-25 ファイザー製薬株式会社 Ｎ−ヒドロキシ尿素系抗炎症剤
PL180668B1 (pl) * 1994-08-04 2001-03-30 Minnesota Mining & Mfg Srodek do hamowania biosyntezy leukotrienu i kompozycja farmaceutyczna do leczenia stanu wrazliwego na hamowanie biosyntezy leukotrienu PL PL PL PL PL
US5612377A (en) * 1994-08-04 1997-03-18 Minnesota Mining And Manufacturing Company Method of inhibiting leukotriene biosynthesis
CN1087291C (zh) * 1995-06-07 2002-07-10 美国辉瑞有限公司 作为抗发炎剂的n－羟基脲
US6858668B2 (en) * 1997-08-27 2005-02-22 Rhodia Chimie Method for masking polyisocyanates in emulsion
AU3631500A (en) 1999-03-19 2000-10-09 Du Pont Pharmaceuticals Company N-adamant-1-yl-n'-(4-chlorobenzothiazol-2-yl) urea useful in the treatment of inflammation and as an anticancer radiosensitizing agent
CA2450073C (en) 2001-07-25 2017-08-29 Biomarin Pharmaceutical Inc. Compositions and methods for modulating blood-brain barrier transport
AU2005236020A1 (en) * 2004-04-20 2005-11-03 Merck & Co., Inc. 1,3,5-substituted phenyl derivative compounds useful as beta-secretase inhibitors for the treatment of Alzheimer's disease
PT1889198E (pt) 2005-04-28 2015-03-06 Proteus Digital Health Inc Sistema fármaco-informático
US8795627B2 (en) 2007-03-21 2014-08-05 Raptor Pharmaceuticals Inc. Treatment of liver disorders by administration of RAP conjugates
WO2010095940A2 (en) 2009-02-20 2010-08-26 To-Bbb Holding B.V. Glutathione-based drug delivery system
NZ596876A (en) 2009-05-06 2014-01-31 Lab Skin Care Inc Dermal delivery compositions comprising active agent-calcium phosphate particle complexes and methods of using the same
US20120077778A1 (en) 2010-09-29 2012-03-29 Andrea Bourdelais Ladder-Frame Polyether Conjugates
CN111044641B (zh) * 2019-12-31 2023-04-07 北京振东光明药物研究院有限公司 羟基脲及其制剂的检测方法和应用

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK117986A (da) * 1985-03-16 1986-09-17 Wellcome Found Arylderivater, fremgangsmaader til deres fremstilling og deres anvendelse
GB8531838D0 (en) * 1985-12-30 1986-02-05 Wellcome Found Aryl derivatives
DE3882732T2 (de) * 1987-02-10 1993-12-02 Abbott Lab Indol, Benzofuran, Benzothiophen enthaltende, Lipoxygenase hemmende Verbindungen.
ES2053609T3 (es) * 1987-04-24 1994-08-01 Abbott Lab Derivados de urea inhibidores de lipoxigenasa.
US4822809A (en) * 1987-11-13 1989-04-18 Abbott Laboratories Benzazole lipoxygenase inhibiting compounds
CA2012716A1 (en) * 1989-03-22 1990-09-22 Akito Tanaka Thiazole compounds, processes for the preparation thereof and pharmaceutical composition comprising the same

Also Published As

Publication number Publication date
CA2099565C (en) 1996-05-07
PT99982A (pt) 1993-01-29
EP0566593A1 (en) 1993-10-27
WO1992012141A1 (en) 1992-07-23
IE920046A1 (en) 1992-07-15
US5464849A (en) 1995-11-07
FI933136A0 (fi) 1993-07-08
JP2528741B2 (ja) 1996-08-28
JPH04297460A (ja) 1992-10-21

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Legal Events

Date Code Title Description
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