FI945281A7 - Heterosykliset yhdisteet, niiden valmistus ja käyttö - Google Patents

Heterosykliset yhdisteet, niiden valmistus ja käyttö Download PDF

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Publication number
FI945281A7
FI945281A7 FI945281A FI945281A FI945281A7 FI 945281 A7 FI945281 A7 FI 945281A7 FI 945281 A FI945281 A FI 945281A FI 945281 A FI945281 A FI 945281A FI 945281 A7 FI945281 A7 FI 945281A7
Authority
FI
Finland
Prior art keywords
preparation
heterocyclic compounds
heterocyclic
compounds
Prior art date
Application number
FI945281A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI945281A0 (fi
FI945281L (fi
Inventor
Takayuki Doi
Hideaki Natsugari
Takenori Ishimaru
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI945281A0 publication Critical patent/FI945281A0/fi
Publication of FI945281L publication Critical patent/FI945281L/fi
Publication of FI945281A7 publication Critical patent/FI945281A7/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/04Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P23/00Anaesthetics
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D409/00Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
    • C07D409/02Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
    • C07D409/04Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D471/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D495/00Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Pain & Pain Management (AREA)
  • Rheumatology (AREA)
  • Anesthesiology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Peptides Or Proteins (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI945281A 1993-11-10 1994-11-09 Heterosykliset yhdisteet, niiden valmistus ja käyttö FI945281A7 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
JP28117893 1993-11-10
JP33748893 1993-12-28
JP3363794 1994-03-03
JP13855194 1994-06-21

Publications (3)

Publication Number Publication Date
FI945281A0 FI945281A0 (fi) 1994-11-09
FI945281L FI945281L (fi) 1995-05-11
FI945281A7 true FI945281A7 (fi) 1995-05-11

Family

ID=27459814

Family Applications (1)

Application Number Title Priority Date Filing Date
FI945281A FI945281A7 (fi) 1993-11-10 1994-11-09 Heterosykliset yhdisteet, niiden valmistus ja käyttö

Country Status (16)

Country Link
US (1) US5585385A (enExample)
EP (1) EP0652218B1 (enExample)
KR (1) KR950014108A (enExample)
CN (1) CN1052004C (enExample)
AT (1) ATE203024T1 (enExample)
AU (1) AU678295B2 (enExample)
BR (1) BR9404403A (enExample)
CA (1) CA2135440A1 (enExample)
DE (1) DE69427675T2 (enExample)
FI (1) FI945281A7 (enExample)
HU (1) HUT68810A (enExample)
IL (1) IL111590A0 (enExample)
NO (1) NO301764B1 (enExample)
NZ (1) NZ264887A (enExample)
RU (1) RU2135471C1 (enExample)
TW (1) TW263498B (enExample)

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US6239132B1 (en) 1999-04-23 2001-05-29 Merck & Co., Inc. Thrombin inhibitors
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NZ533540A (en) 2002-01-18 2006-04-28 Kyorin Seiyaku Kk Fused bicyclic pyrimidine derivatives that act as effective tachykinin receptor antagonists such as NK1 to treat tachykinin receptor-related pathological conditions
CA2476162A1 (en) * 2002-02-13 2003-08-21 Takeda Chemical Industries, Ltd. Jnk inhibitor
WO2003077850A2 (en) 2002-03-15 2003-09-25 Merck & Co., Inc. N-(substituted benzyl)-8-hydroxy-1,6-naphthyridine-7- carboxamides useful as hiv integrase inhibitors
CN1310922C (zh) * 2002-03-26 2007-04-18 杏林制药株式会社 作为速激肽受体拮抗剂的稠合双环吡啶衍生物
KR20050084292A (ko) * 2002-12-13 2005-08-26 뉴로젠 코포레이션 캅사이신 수용체 조절체로서 2-치환된 퀴나졸린-4-일아민동족체
RU2229475C1 (ru) * 2003-03-06 2004-05-27 ООО "Исследовательский институт химического разнообразия 6-сульфамоилхинолин-4-карбоновые кислоты, их производные и комбинаторная библиотека
EP1667973B1 (en) * 2003-09-23 2013-12-04 Merck Sharp & Dohme Corp. Quinoline potassium channel inhibitors
CA2539541C (en) * 2003-09-23 2010-06-29 Merck & Co., Inc. Isoquinolinone potassium channel inhibitors
JPWO2005068427A1 (ja) * 2004-01-14 2007-09-06 武田薬品工業株式会社 カルボキサミド誘導体およびその用途
KR100781704B1 (ko) * 2005-04-20 2007-12-03 에스케이케미칼주식회사 피리딘 유도체와 이의 제조방법, 및 이를 포함하는약제조성물
AR057325A1 (es) 2005-05-25 2007-11-28 Progenics Pharm Inc Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos
TW200740782A (en) * 2005-09-01 2007-11-01 Tanabe Seiyaku Co Thiomorpholine compound and process for preparing the same
RU2359962C1 (ru) * 2007-12-13 2009-06-27 Общество с ограниченной ответственностью "Консорциум-ПИК" (ООО "Консорциум-ПИК") Нейротропное средство и способ его получения
RU2429230C1 (ru) * 2010-05-27 2011-09-20 Учреждение Российской академии наук Институт проблем химико-энергетических технологий Сибирского отделения РАН (ИПХЭТ СО РАН) Способ получения n-метил-4-бензилкарбамидопиридиния йодида
EP2681200A4 (en) * 2011-03-03 2015-05-27 Zalicus Pharmaceuticals Ltd INHIBITORS OF BENZIMIDAZOLE TYPE OF SODIUM CHANNEL
CN102358730A (zh) * 2011-08-24 2012-02-22 济南赛文医药技术有限公司 一种小分子mek蛋白激酶抑制剂
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ES2625945T3 (es) * 2012-11-14 2017-07-21 Glaxosmithkline Llc Tieno[3,2-c]piridin-4(5H)-onas como inhibidores de bet
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RU2770050C2 (ru) 2015-03-04 2022-04-14 Ванда Фармасьютиклз Инк. Способ лечения с применением традипитанта
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MA52814A (fr) 2016-04-15 2022-04-27 Abbvie Inc Inhibiteurs de bromodomaine
EP3363793A1 (en) 2017-02-15 2018-08-22 Merck Patent GmbH Hydrophobic compounds for optically active devices
EP3363786A1 (en) 2017-02-15 2018-08-22 Merck Patent GmbH Compounds for optically active devices
EP4487912A3 (en) 2017-09-13 2025-03-26 Vanda Pharmaceuticals Inc. Improved treatment of atopic dermatitis with tradipitant
AU2021274818A1 (en) 2020-05-20 2022-09-29 AMO Ireland Azacoumarin and azathiocoumarin derivatives for use in optically active devices
US11753413B2 (en) 2020-06-19 2023-09-12 Incyte Corporation Substituted pyrrolo[2,1-f][1,2,4]triazine compounds as JAK2 V617F inhibitors
WO2021257857A1 (en) 2020-06-19 2021-12-23 Incyte Corporation Naphthyridinone compounds as jak2 v617f inhibitors
US11767323B2 (en) 2020-07-02 2023-09-26 Incyte Corporation Tricyclic pyridone compounds as JAK2 V617F inhibitors
AU2021300429A1 (en) 2020-07-02 2023-02-16 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
US11661422B2 (en) 2020-08-27 2023-05-30 Incyte Corporation Tricyclic urea compounds as JAK2 V617F inhibitors
WO2022140231A1 (en) 2020-12-21 2022-06-30 Incyte Corporation Deazaguaine compounds as jak2 v617f inhibitors
TW202302589A (zh) 2021-02-25 2023-01-16 美商英塞特公司 作為jak2 v617f抑制劑之螺環內醯胺
TW202337453A (zh) 2022-03-17 2023-10-01 美商英塞特公司 作為jak2 v617f抑制劑之三環脲化合物

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Also Published As

Publication number Publication date
CA2135440A1 (en) 1995-05-11
KR950014108A (ko) 1995-06-15
BR9404403A (pt) 1995-07-18
US5585385A (en) 1996-12-17
NO944252D0 (no) 1994-11-08
FI945281A0 (fi) 1994-11-09
EP0652218B1 (en) 2001-07-11
RU94040174A (ru) 1996-10-10
HUT68810A (en) 1995-05-19
DE69427675T2 (de) 2002-05-16
NO301764B1 (no) 1997-12-08
EP0652218A1 (en) 1995-05-10
CN1052004C (zh) 2000-05-03
TW263498B (enExample) 1995-11-21
DE69427675D1 (de) 2001-08-16
NZ264887A (en) 1996-12-20
FI945281L (fi) 1995-05-11
NO944252L (no) 1995-05-11
ATE203024T1 (de) 2001-07-15
IL111590A0 (en) 1995-01-24
RU2135471C1 (ru) 1999-08-27
HU9403230D0 (en) 1995-01-30
AU678295B2 (en) 1997-05-22
AU7773894A (en) 1995-05-18
CN1107476A (zh) 1995-08-30

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