FI945281A7 - Heterosykliset yhdisteet, niiden valmistus ja käyttö - Google Patents
Heterosykliset yhdisteet, niiden valmistus ja käyttö Download PDFInfo
- Publication number
- FI945281A7 FI945281A7 FI945281A FI945281A FI945281A7 FI 945281 A7 FI945281 A7 FI 945281A7 FI 945281 A FI945281 A FI 945281A FI 945281 A FI945281 A FI 945281A FI 945281 A7 FI945281 A7 FI 945281A7
- Authority
- FI
- Finland
- Prior art keywords
- preparation
- heterocyclic compounds
- heterocyclic
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
- C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
- C07D401/04—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P23/00—Anaesthetics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D409/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms
- C07D409/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings
- C07D409/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having sulfur atoms as the only ring hetero atoms containing two hetero rings directly linked by a ring-member-to-ring-member bond
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
- C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
- C07D495/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Public Health (AREA)
- Pain & Pain Management (AREA)
- Rheumatology (AREA)
- Anesthesiology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
- Plural Heterocyclic Compounds (AREA)
- Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
- Agricultural Chemicals And Associated Chemicals (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Peptides Or Proteins (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| JP28117893 | 1993-11-10 | ||
| JP33748893 | 1993-12-28 | ||
| JP3363794 | 1994-03-03 | ||
| JP13855194 | 1994-06-21 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI945281A0 FI945281A0 (fi) | 1994-11-09 |
| FI945281L FI945281L (fi) | 1995-05-11 |
| FI945281A7 true FI945281A7 (fi) | 1995-05-11 |
Family
ID=27459814
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI945281A FI945281A7 (fi) | 1993-11-10 | 1994-11-09 | Heterosykliset yhdisteet, niiden valmistus ja käyttö |
Country Status (16)
| Country | Link |
|---|---|
| US (1) | US5585385A (enExample) |
| EP (1) | EP0652218B1 (enExample) |
| KR (1) | KR950014108A (enExample) |
| CN (1) | CN1052004C (enExample) |
| AT (1) | ATE203024T1 (enExample) |
| AU (1) | AU678295B2 (enExample) |
| BR (1) | BR9404403A (enExample) |
| CA (1) | CA2135440A1 (enExample) |
| DE (1) | DE69427675T2 (enExample) |
| FI (1) | FI945281A7 (enExample) |
| HU (1) | HUT68810A (enExample) |
| IL (1) | IL111590A0 (enExample) |
| NO (1) | NO301764B1 (enExample) |
| NZ (1) | NZ264887A (enExample) |
| RU (1) | RU2135471C1 (enExample) |
| TW (1) | TW263498B (enExample) |
Families Citing this family (49)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO309272B1 (no) * | 1995-03-24 | 2001-01-08 | Takeda Chemical Industries Ltd | Cykliske forbindelser, preparater inneholdende forbindelsene samt mellomprodukter for fremstilling av forbindelsene |
| US5770590A (en) * | 1995-03-24 | 1998-06-23 | Takeda Chemical Industries, Ltd. | Cyclic compounds, their prudiction and use |
| FR2732221B1 (fr) * | 1995-03-28 | 1997-04-25 | Oreal | Utilisation d'un antagoniste de cgrp pour traiter les rougeurs cutanees d'origine neurogene et composition obtenue |
| GB9524104D0 (en) | 1995-11-24 | 1996-01-24 | Smithkline Beecham Spa | Novel compounds |
| WO1999015169A1 (en) * | 1997-09-23 | 1999-04-01 | Merck & Co., Inc. | Thrombin inhibitors |
| US6087373A (en) * | 1997-09-23 | 2000-07-11 | Merck & Co., Inc. | Thrombin inhibitors |
| US6727258B2 (en) * | 1997-10-29 | 2004-04-27 | King Pharmaceutical Research & Development, Inc. | Allosteric adenosine receptor modulators |
| US5939432A (en) * | 1997-10-29 | 1999-08-17 | Medco Research, Inc. | Thiophenes useful for modulating the adenosine receptor |
| US6323214B1 (en) | 1997-10-29 | 2001-11-27 | Medco Research, Inc | Allosteric adenosine receptor modulators |
| AU5305299A (en) * | 1998-08-26 | 2000-03-21 | Tanabe Seiyaku Co., Ltd. | Naphthyridine derivatives and process for the preparation thereof |
| WO2000023443A1 (en) * | 1998-10-22 | 2000-04-27 | Akzo Nobel N.V. | Tetrahydropyridopyridine derivatives and intermediates for producing the same |
| US6239132B1 (en) | 1999-04-23 | 2001-05-29 | Merck & Co., Inc. | Thrombin inhibitors |
| CA2374654A1 (en) | 1999-06-04 | 2000-12-14 | Merck & Co., Inc. | Thrombin inhibitors |
| US20040152727A1 (en) * | 2001-05-18 | 2004-08-05 | Hay Douglas William Pierre | Novel use |
| JPWO2003050123A1 (ja) * | 2001-12-10 | 2005-04-21 | 杏林製薬株式会社 | タキキニン受容体拮抗剤としての縮合二環式ピリジン誘導体 |
| EP1473295B1 (en) * | 2002-01-18 | 2009-04-01 | Kyorin Pharmaceutical Co., Ltd. | Fused bicyclic pyrimidine derivatives |
| EP1484320A1 (en) * | 2002-02-13 | 2004-12-08 | Takeda Chemical Industries, Ltd. | Jnk inhibitor |
| DE60323743D1 (en) | 2002-03-15 | 2008-11-06 | Merck & Co Inc | N-(substituierte benzyl)-8-hydroxy-1,6-naphthyridin-7- carbonsäureamide als hiv-integrase-hemmer |
| AU2003221204B2 (en) | 2002-03-26 | 2008-09-18 | Kyorin Pharmaceutical Co., Ltd. | Fused bicyclic pyridine derivative as tachykinin receptor antagonist |
| CA2509239A1 (en) * | 2002-12-13 | 2004-07-01 | Neurogen Corporation | Carboxylic acid, phosphate or phosphonate substituted quinazolin-4-ylamine analogues as capsaicin receptor modulators |
| RU2229475C1 (ru) * | 2003-03-06 | 2004-05-27 | ООО "Исследовательский институт химического разнообразия | 6-сульфамоилхинолин-4-карбоновые кислоты, их производные и комбинаторная библиотека |
| AU2004276267B2 (en) * | 2003-09-23 | 2010-08-19 | Merck Sharp & Dohme Corp. | Isoquinolinone potassium channel inhibitors |
| CN1856470A (zh) * | 2003-09-23 | 2006-11-01 | 默克公司 | 喹啉钾通道抑制剂 |
| EP1705176A4 (en) * | 2004-01-14 | 2009-06-03 | Takeda Pharmaceutical | CARBOXYLAMIDE DERIVATIVE AND ITS USE |
| KR100781704B1 (ko) * | 2005-04-20 | 2007-12-03 | 에스케이케미칼주식회사 | 피리딘 유도체와 이의 제조방법, 및 이를 포함하는약제조성물 |
| AR057325A1 (es) | 2005-05-25 | 2007-11-28 | Progenics Pharm Inc | Sintesis de (s)-n-metilnaltrexona, composiciones farmaceuticas y usos |
| AR056048A1 (es) * | 2005-09-01 | 2007-09-12 | Tanabe Seiyaku Co | Compuesto tiomorfolina y procedimiento para preparar el mismo |
| RU2359962C1 (ru) * | 2007-12-13 | 2009-06-27 | Общество с ограниченной ответственностью "Консорциум-ПИК" (ООО "Консорциум-ПИК") | Нейротропное средство и способ его получения |
| RU2429230C1 (ru) * | 2010-05-27 | 2011-09-20 | Учреждение Российской академии наук Институт проблем химико-энергетических технологий Сибирского отделения РАН (ИПХЭТ СО РАН) | Способ получения n-метил-4-бензилкарбамидопиридиния йодида |
| ES2786298T3 (es) * | 2011-03-03 | 2020-10-09 | Zalicus Pharmaceuticals Ltd | Inhibidores de benzimidazol del canal de sodio |
| CN102358730A (zh) * | 2011-08-24 | 2012-02-22 | 济南赛文医药技术有限公司 | 一种小分子mek蛋白激酶抑制剂 |
| WO2013097052A1 (en) * | 2011-12-30 | 2013-07-04 | Abbott Laboratories | Bromodomain inhibitors |
| ES2625945T3 (es) | 2012-11-14 | 2017-07-21 | Glaxosmithkline Llc | Tieno[3,2-c]piridin-4(5H)-onas como inhibidores de bet |
| MX2015017963A (es) | 2013-06-28 | 2016-11-10 | Abbvie Inc | Inhibidores de bromodominio. |
| BR112017018620A2 (pt) | 2015-03-04 | 2018-04-17 | Vanda Pharmaceuticals Inc. | método de administração de tradipitanto, e, tradipitanto. |
| EP3133065A1 (en) | 2015-08-21 | 2017-02-22 | Merck Patent GmbH | Compounds for optically active devices |
| SG11201808003RA (en) | 2016-04-15 | 2018-10-30 | Abbvie Inc | Bromodomain inhibitors |
| EP3363786A1 (en) | 2017-02-15 | 2018-08-22 | Merck Patent GmbH | Compounds for optically active devices |
| EP3363793A1 (en) | 2017-02-15 | 2018-08-22 | Merck Patent GmbH | Hydrophobic compounds for optically active devices |
| CA3073998A1 (en) | 2017-09-13 | 2019-03-21 | Vanda Pharmaceuticals Inc. | Improved treatment of atopic dermatitis with tradipitant |
| US20230203214A1 (en) | 2020-05-20 | 2023-06-29 | Merck Patent Gmbh | Azacoumarin and azathiocoumarin derivatives for use in optically active devices |
| WO2021257863A1 (en) | 2020-06-19 | 2021-12-23 | Incyte Corporation | Pyrrolotriazine compounds as jak2 v617f inhibitors |
| US11691971B2 (en) | 2020-06-19 | 2023-07-04 | Incyte Corporation | Naphthyridinone compounds as JAK2 V617F inhibitors |
| US11767323B2 (en) | 2020-07-02 | 2023-09-26 | Incyte Corporation | Tricyclic pyridone compounds as JAK2 V617F inhibitors |
| IL299612A (en) | 2020-07-02 | 2023-03-01 | Incyte Corp | Tricyclic urea compounds as JAK2 V617F inhibitors |
| US11661422B2 (en) | 2020-08-27 | 2023-05-30 | Incyte Corporation | Tricyclic urea compounds as JAK2 V617F inhibitors |
| WO2022140231A1 (en) | 2020-12-21 | 2022-06-30 | Incyte Corporation | Deazaguaine compounds as jak2 v617f inhibitors |
| US11958861B2 (en) | 2021-02-25 | 2024-04-16 | Incyte Corporation | Spirocyclic lactams as JAK2 V617F inhibitors |
| EP4493558A1 (en) | 2022-03-17 | 2025-01-22 | Incyte Corporation | Tricyclic urea compounds as jak2 v617f inhibitors |
Family Cites Families (14)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| HU173438B (hu) * | 1975-11-27 | 1979-05-28 | Chinoin Gyogyszer Es Vegyeszet | Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom |
| IL75987A (en) * | 1984-08-25 | 1991-07-18 | Goedecke Ag | Tri-and tetrasubstituted-1,4-dihydro-1,6-naphthyridine-3-carboxylic acid derivatives,their preparation and pharmaceutical compositions containing them |
| IE892088L (en) * | 1988-07-12 | 1990-01-12 | William Henry Deryk Morris | Quinoline derivatives, their production and use |
| TW205037B (enExample) * | 1989-10-06 | 1993-05-01 | Takeda Pharm Industry Co Ltd | |
| FR2654725B1 (fr) * | 1989-11-23 | 1992-02-14 | Rhone Poulenc Sante | Nouveaux derives de l'isoindolone, leur preparation et les compositions pharmaceutiques qui les contiennent. |
| WO1991009844A1 (en) * | 1990-01-04 | 1991-07-11 | Pfizer Inc. | Substance p antagonists |
| ATE116645T1 (de) * | 1990-02-10 | 1995-01-15 | Takeda Chemical Industries Ltd | Chromenderivate, deren herstellung und verwendung. |
| US5143919A (en) * | 1990-08-17 | 1992-09-01 | Takeda Chemical Industries, Ltd. | Thienopyridine derivatives and their pharmaceutical use |
| DE69110828T2 (de) * | 1990-10-16 | 1995-11-30 | Takeda Chemical Industries Ltd | Heterozyklische Aminderivate, deren Herstellung und deren Verwendung. |
| TW241258B (enExample) * | 1992-04-15 | 1995-02-21 | Takeda Pharm Industry Co Ltd | |
| DE4215588A1 (de) * | 1992-05-12 | 1993-11-18 | Bayer Ag | Biphenylmethyl-substituierte Pyridone |
| DE4215587A1 (de) * | 1992-05-12 | 1993-11-18 | Bayer Ag | Sulfonylbenzyl-substituierte Benzo- und Pyridopyridone |
| NO179904C (no) * | 1992-09-04 | 1997-01-08 | Takeda Chemical Industries Ltd | Kondenserte heterocykliske forbindelser og deres anvendelse |
| JPH06298757A (ja) * | 1993-04-15 | 1994-10-25 | Kissei Pharmaceut Co Ltd | ピペリジノ−３，４−ジヒドロカルボスチリル誘導体 |
-
1994
- 1994-11-05 TW TW083110229A patent/TW263498B/zh active
- 1994-11-08 NO NO944252A patent/NO301764B1/no not_active IP Right Cessation
- 1994-11-08 AT AT94117576T patent/ATE203024T1/de not_active IP Right Cessation
- 1994-11-08 DE DE69427675T patent/DE69427675T2/de not_active Expired - Fee Related
- 1994-11-08 EP EP94117576A patent/EP0652218B1/en not_active Expired - Lifetime
- 1994-11-09 CA CA002135440A patent/CA2135440A1/en not_active Abandoned
- 1994-11-09 RU RU94040174A patent/RU2135471C1/ru active
- 1994-11-09 NZ NZ264887A patent/NZ264887A/en unknown
- 1994-11-09 FI FI945281A patent/FI945281A7/fi unknown
- 1994-11-09 BR BR9404403A patent/BR9404403A/pt not_active Application Discontinuation
- 1994-11-09 AU AU77738/94A patent/AU678295B2/en not_active Ceased
- 1994-11-10 US US08/338,762 patent/US5585385A/en not_active Expired - Fee Related
- 1994-11-10 HU HU9403230A patent/HUT68810A/hu unknown
- 1994-11-10 KR KR1019940029451A patent/KR950014108A/ko not_active Abandoned
- 1994-11-10 IL IL11159094A patent/IL111590A0/xx unknown
- 1994-11-10 CN CN94113866A patent/CN1052004C/zh not_active Expired - Fee Related
Also Published As
| Publication number | Publication date |
|---|---|
| CN1052004C (zh) | 2000-05-03 |
| RU2135471C1 (ru) | 1999-08-27 |
| EP0652218B1 (en) | 2001-07-11 |
| EP0652218A1 (en) | 1995-05-10 |
| FI945281A0 (fi) | 1994-11-09 |
| AU678295B2 (en) | 1997-05-22 |
| NZ264887A (en) | 1996-12-20 |
| NO944252D0 (no) | 1994-11-08 |
| FI945281L (fi) | 1995-05-11 |
| ATE203024T1 (de) | 2001-07-15 |
| KR950014108A (ko) | 1995-06-15 |
| TW263498B (enExample) | 1995-11-21 |
| CA2135440A1 (en) | 1995-05-11 |
| IL111590A0 (en) | 1995-01-24 |
| BR9404403A (pt) | 1995-07-18 |
| AU7773894A (en) | 1995-05-18 |
| HU9403230D0 (en) | 1995-01-30 |
| NO301764B1 (no) | 1997-12-08 |
| US5585385A (en) | 1996-12-17 |
| RU94040174A (ru) | 1996-10-10 |
| HUT68810A (en) | 1995-05-19 |
| CN1107476A (zh) | 1995-08-30 |
| DE69427675T2 (de) | 2002-05-16 |
| DE69427675D1 (de) | 2001-08-16 |
| NO944252L (no) | 1995-05-11 |
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