FI943146A0 - Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen - Google Patents

Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen

Info

Publication number
FI943146A0
FI943146A0 FI943146A FI943146A FI943146A0 FI 943146 A0 FI943146 A0 FI 943146A0 FI 943146 A FI943146 A FI 943146A FI 943146 A FI943146 A FI 943146A FI 943146 A0 FI943146 A0 FI 943146A0
Authority
FI
Finland
Prior art keywords
pct
expression
free
staphylokinases
signal peptides
Prior art date
Application number
FI943146A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI943146A (fi
Inventor
Detlev Behnke
Bernhard Schlott
Sybille Albrecht
Karl-Heinz Guehrs
Manfred Hartmann
Original Assignee
Medac Klinische Spezialpraep
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from DE4143279A external-priority patent/DE4143279A1/de
Priority claimed from DE4240801A external-priority patent/DE4240801A1/de
Application filed by Medac Klinische Spezialpraep filed Critical Medac Klinische Spezialpraep
Publication of FI943146A publication Critical patent/FI943146A/fi
Publication of FI943146A0 publication Critical patent/FI943146A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/195Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
    • C07K14/305Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
    • C07K14/31Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N15/00Mutation or genetic engineering; DNA or RNA concerning genetic engineering, vectors, e.g. plasmids, or their isolation, preparation or purification; Use of hosts therefor
    • C12N15/09Recombinant DNA-technology
    • C12N15/11DNA or RNA fragments; Modified forms thereof; Non-coding nucleic acids having a biological activity
    • C12N15/52Genes encoding for enzymes or proenzymes
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K16/00Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies
    • C07K16/40Immunoglobulins [IGs], e.g. monoclonal or polyclonal antibodies against enzymes
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12NMICROORGANISMS OR ENZYMES; COMPOSITIONS THEREOF; PROPAGATING, PRESERVING, OR MAINTAINING MICROORGANISMS; MUTATION OR GENETIC ENGINEERING; CULTURE MEDIA
    • C12N9/00Enzymes; Proenzymes; Compositions thereof; Processes for preparing, activating, inhibiting, separating or purifying enzymes
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Biophysics (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Biomedical Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Wood Science & Technology (AREA)
  • Zoology (AREA)
  • Biotechnology (AREA)
  • General Engineering & Computer Science (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Microbiology (AREA)
  • Immunology (AREA)
  • Physics & Mathematics (AREA)
  • Plant Pathology (AREA)
  • Peptides Or Proteins (AREA)
  • Saccharide Compounds (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Enzymes And Modification Thereof (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Measurement And Recording Of Electrical Phenomena And Electrical Characteristics Of The Living Body (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
FI943146A 1991-12-30 1994-06-30 Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen FI943146A0 (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
DE4143279A DE4143279A1 (de) 1991-12-30 1991-12-30 Neue plasminogenaktivatoren, die sie kodierenden dna-sequenzen, zugehoerige expressionsplasmide und rekombinante escherichia coli-staemme, verfahren zur produktion dieser proteine und ihre verwendung
DE4220516 1992-06-22
DE4240801A DE4240801A1 (de) 1992-12-01 1992-12-01 Reife methioninfreie Staphylokinasen, die sie kodierenden DNA-Sequenzen, zugehörige Expressionsplasmide und rekombinante Escherichia coli-Stämme, Verfahren zur Herstellung dieser Proteine und ihre Verwendung
PCT/EP1992/002989 WO1993013209A1 (fr) 1991-12-30 1992-12-28 Staphilokinases exemptes de peptides-signal d'expression

Publications (2)

Publication Number Publication Date
FI943146A FI943146A (fi) 1994-06-30
FI943146A0 true FI943146A0 (fi) 1994-06-30

Family

ID=27203268

Family Applications (1)

Application Number Title Priority Date Filing Date
FI943146A FI943146A0 (fi) 1991-12-30 1994-06-30 Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen

Country Status (14)

Country Link
US (2) US5801037A (fr)
EP (1) EP0621899B1 (fr)
JP (1) JP3310672B2 (fr)
KR (1) KR100221150B1 (fr)
AT (1) ATE139570T1 (fr)
AU (1) AU669149B2 (fr)
DE (1) DE59206628D1 (fr)
DK (1) DK0621899T3 (fr)
ES (1) ES2089784T3 (fr)
FI (1) FI943146A0 (fr)
GR (1) GR3020529T3 (fr)
HK (1) HK1005886A1 (fr)
HU (1) HU218043B (fr)
WO (1) WO1993013209A1 (fr)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0621899B1 (fr) * 1991-12-30 1996-06-19 Medac Gesellschaft für klinische Spezialpräparate mbH Staphylokinases exemptes de peptides-signal d'expression
CN1035192C (zh) * 1994-04-04 1997-06-18 上海医科大学 一种重组葡激酶的制备方法
JPH08289790A (ja) * 1995-01-06 1996-11-05 Leuven Res & Dev Vzw 新規なスタフィロキナーゼ誘導体
DE69534056D1 (de) * 1995-01-06 2005-04-14 Leuven Res & Dev V Z W Neue staphylokinase Derivate
EP0721982A1 (fr) * 1995-01-06 1996-07-17 Leuven Research & Development V.Z.W. Des dérivés nouveaux de la staphylokinase
US5846943A (en) * 1996-11-08 1998-12-08 Synsorb Biotech, Inc. Solid support matricles containing a toxin binding oligosaccharide
CN1059926C (zh) * 1997-07-19 2000-12-27 张其玖 葡激酶基因及其高表达工程菌株
WO1999040198A2 (fr) * 1998-02-04 1999-08-12 Thromb-X N.V. Identification, production et utilisation de derives de la staphylokinase avec immunogenecite et/ou clearance reduites
US7781209B2 (en) * 2005-09-25 2010-08-24 Multispan, Inc. GPCR-expressing cell lines

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5867181A (ja) * 1981-10-16 1983-04-21 Yakult Honsha Co Ltd スタフイロキナーゼ産生遺伝情報を担うdna断片組み換え体dnaおよびそれを導入した大腸菌
WO1987002732A1 (fr) * 1985-11-01 1987-05-07 Vaughan Thomas L Assemblage de suspension d'un materiel medical ou autre
JP2895626B2 (ja) * 1990-12-17 1999-05-24 株式会社 ヤクルト本社 血栓溶解剤
ES2096617T3 (es) * 1991-06-28 1997-03-16 Leuven Res & Dev Vzw Uso de estafiloquinasa para la preparacion de una composicion farmaceutica para tratar trombosis arterial.
EP0621899B1 (fr) * 1991-12-30 1996-06-19 Medac Gesellschaft für klinische Spezialpräparate mbH Staphylokinases exemptes de peptides-signal d'expression

Also Published As

Publication number Publication date
FI943146A (fi) 1994-06-30
GR3020529T3 (en) 1996-10-31
JP3310672B2 (ja) 2002-08-05
EP0621899B1 (fr) 1996-06-19
AU669149B2 (en) 1996-05-30
EP0621899A1 (fr) 1994-11-02
DK0621899T3 (da) 1996-10-28
US6010897A (en) 2000-01-04
KR100221150B1 (ko) 1999-10-01
ATE139570T1 (de) 1996-07-15
HU218043B (hu) 2000-05-28
HK1005886A1 (en) 1999-01-29
US5801037A (en) 1998-09-01
ES2089784T3 (es) 1996-10-01
HUT68067A (en) 1995-05-29
DE59206628D1 (en) 1996-07-25
HU9401949D0 (en) 1994-11-28
AU3347293A (en) 1993-07-28
JPH07502652A (ja) 1995-03-23
KR940703920A (ko) 1994-12-12
WO1993013209A1 (fr) 1993-07-08

Similar Documents

Publication Publication Date Title
DE69435049D1 (de) Chimäre proteine zur vermeidung der komplementaktivierung
DE69534588D1 (de) Protocadherin-proteine und verwendungen davon
DE68929043D1 (de) Für androgen-rezeptor-protein kodierende dna
NO892033L (no) Fibronectinbindende protein.
ATE476495T1 (de) Bazillus thuringiensis und dessen insektizide proteine
FI962247A (fi) Uudet apoptoosia muuntavat proteiinit, niitä koodaava DNA ja näiden käyttömenetelmät
ATE135371T1 (de) Mit akuter pankreatitis assoziiertes protein, mittel zur diagnose von akuter pankreatitis
DE69839566D1 (de) Chimäre polypeptide, die das fragment b des shigatoxins sowie peptide von therapeutischem interesse enthalten
SE8902532L (sv) Bestaemning av plasmaproteiner
FI943146A0 (fi) Signaalipeptideistä vapaiden stafylokinaasien ilmentyminen
KR980002066A (ko) 변이형 인간 성장호르몬 및 그의 용도
DK0613499T3 (da) Humame IT-4-mutantproteiner
ATE255638T1 (de) Nukleotidsequenzen und gegen cycloheximid resistente proteine
DK0719328T3 (da) Genet GRB 3-3, varianter deraf og anvendelse deraf
DE69333952D1 (de) Klonering von dem gen für das t gondii protein gp 28.5 peptidfragmente aus diesem protein und ihre verwendungen.
DK0649433T3 (da) Antigeniske regioner fra komplekser af tumorfrigivne partikler (TLP) og antistoffer mod sådanne.
DE69431603T2 (de) Oligopeptide hergeleitet von fragmenten des c-reaktiven proteins
ATE148744T1 (de) Neue thrombininhibitorische proteine aus landblutegeln
ES2061585T3 (es) Señal de secrecion de bar1.
DE69130675T2 (de) Klonierung und expression eines rhoptry-assoziierten proteins aus p. falciparum
ATE342972T1 (de) Ifn rezeptor 1 bindende proteine, dafür kodierende dna und verfahren zur regulierung der zellulären antwort auf interferone

Legal Events

Date Code Title Description
GB Transfer or assigment of application

Owner name: THROMB-X N.V.

FD Application lapsed