CN1059926C - 葡激酶基因及其高表达工程菌株 - Google Patents
葡激酶基因及其高表达工程菌株 Download PDFInfo
- Publication number
- CN1059926C CN1059926C CN97105988A CN97105988A CN1059926C CN 1059926 C CN1059926 C CN 1059926C CN 97105988 A CN97105988 A CN 97105988A CN 97105988 A CN97105988 A CN 97105988A CN 1059926 C CN1059926 C CN 1059926C
- Authority
- CN
- China
- Prior art keywords
- lys
- glu
- val
- thr
- aaa
- Prior art date
- Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
- Expired - Fee Related
Links
Images
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07K—PEPTIDES
- C07K14/00—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
- C07K14/195—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria
- C07K14/305—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F)
- C07K14/31—Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from bacteria from Micrococcaceae (F) from Staphylococcus (G)
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
- A61K38/00—Medicinal preparations containing peptides
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- General Health & Medical Sciences (AREA)
- Biochemistry (AREA)
- Biophysics (AREA)
- Life Sciences & Earth Sciences (AREA)
- Genetics & Genomics (AREA)
- Medicinal Chemistry (AREA)
- Molecular Biology (AREA)
- Proteomics, Peptides & Aminoacids (AREA)
- Gastroenterology & Hepatology (AREA)
- Enzymes And Modification Thereof (AREA)
- Micro-Organisms Or Cultivation Processes Thereof (AREA)
Abstract
Description
Claims (7)
Priority Applications (3)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN97105988A CN1059926C (zh) | 1997-07-19 | 1997-07-19 | 葡激酶基因及其高表达工程菌株 |
AU84297/98A AU8429798A (en) | 1997-07-19 | 1998-07-17 | Recombinant staphylokinase and their high expression engineered strain |
PCT/CN1998/000129 WO1999004017A1 (fr) | 1997-07-19 | 1998-07-17 | Staphylokinase recombinante et sa souche manipulee pour une expression elevee |
Applications Claiming Priority (1)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
CN97105988A CN1059926C (zh) | 1997-07-19 | 1997-07-19 | 葡激酶基因及其高表达工程菌株 |
Publications (2)
Publication Number | Publication Date |
---|---|
CN1180106A CN1180106A (zh) | 1998-04-29 |
CN1059926C true CN1059926C (zh) | 2000-12-27 |
Family
ID=5168271
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
CN97105988A Expired - Fee Related CN1059926C (zh) | 1997-07-19 | 1997-07-19 | 葡激酶基因及其高表达工程菌株 |
Country Status (3)
Country | Link |
---|---|
CN (1) | CN1059926C (zh) |
AU (1) | AU8429798A (zh) |
WO (1) | WO1999004017A1 (zh) |
Families Citing this family (3)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1064406C (zh) * | 1998-05-11 | 2001-04-11 | 中国人民解放军军事医学科学院微生物流行病研究所 | 利用基因工程技术生产葡激酶的方法 |
CN101240284B (zh) * | 2007-09-20 | 2012-05-30 | 三峡大学 | 一种重组葡激酶及其高效分泌表达的方法 |
CN114480353B (zh) * | 2022-01-17 | 2023-06-23 | 景泽生物医药(合肥)股份有限公司 | 一种制备重组人奥克纤溶酶的方法 |
Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1096325A (zh) * | 1994-04-04 | 1994-12-14 | 上海医科大学 | 一种重组葡激酶的制备方法 |
CN1109508A (zh) * | 1995-01-23 | 1995-10-04 | 成都世新药物技术开发中心 | 重组葡激酶的全dna序列 |
Family Cites Families (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
JPH0398595A (ja) * | 1989-09-11 | 1991-04-24 | Taisho Pharmaceut Co Ltd | ペプチド類の遺伝子工学的製造法 |
EP0621899B1 (de) * | 1991-12-30 | 1996-06-19 | Medac Gesellschaft für klinische Spezialpräparate mbH | Expression signalpeptid-freier staphylokinasen |
-
1997
- 1997-07-19 CN CN97105988A patent/CN1059926C/zh not_active Expired - Fee Related
-
1998
- 1998-07-17 AU AU84297/98A patent/AU8429798A/en not_active Abandoned
- 1998-07-17 WO PCT/CN1998/000129 patent/WO1999004017A1/zh active Application Filing
Patent Citations (2)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CN1096325A (zh) * | 1994-04-04 | 1994-12-14 | 上海医科大学 | 一种重组葡激酶的制备方法 |
CN1109508A (zh) * | 1995-01-23 | 1995-10-04 | 成都世新药物技术开发中心 | 重组葡激酶的全dna序列 |
Also Published As
Publication number | Publication date |
---|---|
AU8429798A (en) | 1999-02-10 |
CN1180106A (zh) | 1998-04-29 |
WO1999004017A1 (fr) | 1999-01-28 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
Pirnay et al. | Pseudomonas aeruginosa displays an epidemic population structure | |
RU2004137800A (ru) | Иммуногенные последовательности | |
CN1814753A (zh) | 一种耐热超氧化物歧化酶及其编码基因与应用 | |
CN1793177A (zh) | 一种重组胶原蛋白及其合成和表达纯化方法 | |
Zweygarth et al. | In vitro culture and structural differences in the major immunoreactive protein gp36 of geographically distant Ehrlichia canis isolates | |
CN109207459A (zh) | 一种定点突变改造热稳定性提高的琼胶酶突变体 | |
CN1699577A (zh) | 一种β-甘露聚糖酶基因和高效制备 | |
Yang et al. | Nocardiopsis valliformis sp. nov., an alkaliphilic actinomycete isolated from alkali lake soil in China | |
CN1059926C (zh) | 葡激酶基因及其高表达工程菌株 | |
Duan et al. | Enhanced therapeutic efficacy of Listeria-based cancer vaccine with codon-optimized HPV16 E7 | |
Schierack et al. | Genomic and phenotypic analysis of an ESBL-producing E. coli ST1159 clonal lineage from wild birds in Mongolia | |
CN102358896B (zh) | 一种耐热角质酶-cbd融合酶及其突变体和应用 | |
CN108118043A (zh) | 一种热稳定性提高的脂肪酶突变体 | |
CN106834252A (zh) | 一种高稳定型MazF突变体及其应用 | |
CN114807085B (zh) | 一种Taq酶突变体及其应用 | |
CN100344758C (zh) | 中国对虾含单一乳清酸性蛋白结构域的抗菌肽基因及其所编码的抗菌肽与应用 | |
Ebrahimi et al. | Construction of PX-LmGP63 using CRISPR-Cas9 as primary goal for GP63 gene knockout in Leishmania major and leishmanization | |
CN1238378C (zh) | 一种抗菌肽及其编码序列和用途 | |
CN1786175A (zh) | 一种表达重组人tPA的质粒及构建方法 | |
CN102304500B (zh) | 噬菌体tsp4 dna解旋酶和编码这种解旋酶的多核苷酸 | |
Birgani et al. | Antibiotic Characterization of Acinetobacter baumannii isolated from clinical samples and production of recombinant OmpA from resistant strains | |
CN114854778B (zh) | 一种岩藻多糖酶基因Fcn1及其应用 | |
CN1279170C (zh) | 一种具有溶栓活性的沙蚕激酶的编码基因序列及其氨基酸序列 | |
WO2000014274A1 (en) | Method for the identification and speciation of bacteria of the burkholderia cepacia complex | |
Demanche et al. | Absence of mutations associated with sulfa resistance in Pneumocystis carinii dihydropteroate synthase gene from non-human primates |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
C10 | Entry into substantive examination | ||
SE01 | Entry into force of request for substantive examination | ||
C06 | Publication | ||
PB01 | Publication | ||
C53 | Correction of patent for invention or patent application | ||
CB02 | Change of applicant information |
Applicant after: Zhang Qijiu Applicant before: Bai Hansan |
|
COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: BAI HANSAN TO: ZHANG QIJIU |
|
C53 | Correction of patent for invention or patent application | ||
CB02 | Change of applicant information |
Applicant after: Keda Bioengineering Co Ltd, Qingdao Applicant before: Zhang Qijiu |
|
COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: ZHANG QIJIU TO: QINGDAO KEDA BIOLOGY ENGINEERING CO., LTD. |
|
C53 | Correction of patent for invention or patent application | ||
CB02 | Change of applicant information |
Applicant after: Zhang Qijiu Applicant before: Keda Bioengineering Co Ltd, Qingdao |
|
COR | Change of bibliographic data |
Free format text: CORRECT: APPLICANT; FROM: QINGDAO KEDA BIOLOGY ENGINEERING CO., LTD. TO: ZHANG QIJIU |
|
C14 | Grant of patent or utility model | ||
GR01 | Patent grant | ||
C56 | Change in the name or address of the patentee |
Owner name: QINGDAO SHUANGLONG JOINT PHARMACEUTICAL CO., LTD. Free format text: FORMER NAME OR ADDRESS: ZHANG QIJIU |
|
CP03 | Change of name, title or address |
Address after: 266071 Shandong province Qingdao city Hongkong Road No. 7, block 2716 WTO A progenitor to Pui Ying Patentee after: Qingdao Shuanglong United Pharmaceutical Co., Ltd. Address before: 266555 No. 6, Jing Gang mountain road, Qingdao economic and Technological Development Zone, Shandong, China Patentee before: Zhang Qijiu |
|
ASS | Succession or assignment of patent right |
Owner name: QINGDAO HAIMA DECORATION PROJECT CO., LTD. Free format text: FORMER OWNER: QINGDAO SHUANGLONG JOINT PHARMACEUTICAL CO., LTD. Effective date: 20020527 |
|
C41 | Transfer of patent application or patent right or utility model | ||
TR01 | Transfer of patent right |
Effective date of registration: 20020527 Patentee after: Qingdao seahorse Decoration Engineering Co., Ltd. Patentee before: Qingdao Shuanglong United Pharmaceutical Co., Ltd. |
|
C57 | Notification of unclear or unknown address | ||
DD01 | Delivery of document by public notice |
Addressee: Qingdao seahorse Decoration Engineering Co., Ltd. Document name: payment instructions |
|
C57 | Notification of unclear or unknown address | ||
DD01 | Delivery of document by public notice |
Addressee: Qingdao seahorse Decoration Engineering Co., Ltd. Document name: payment instructions |
|
C57 | Notification of unclear or unknown address | ||
DD01 | Delivery of document by public notice |
Addressee: Qingdao seahorse Decoration Engineering Co., Ltd. Document name: Notification of Termination of Patent Right |
|
C17 | Cessation of patent right | ||
CF01 | Termination of patent right due to non-payment of annual fee |
Granted publication date: 20001227 Termination date: 20130719 |