FI942186L - Sytokiinituotantoa indusoivat uretaanit ja ureat - Google Patents

Sytokiinituotantoa indusoivat uretaanit ja ureat Download PDF

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Publication number
FI942186L
FI942186L FI942186A FI942186A FI942186L FI 942186 L FI942186 L FI 942186L FI 942186 A FI942186 A FI 942186A FI 942186 A FI942186 A FI 942186A FI 942186 L FI942186 L FI 942186L
Authority
FI
Finland
Prior art keywords
urethanes
ureas
cytokine production
induce cytokine
induce
Prior art date
Application number
FI942186A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI942186A7 (fi
FI942186A0 (fi
Inventor
Semiramis Ayral-Kaloustian
Steven R Schow
Mila T Du
Jr James J Gibbons
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FI942186A0 publication Critical patent/FI942186A0/fi
Publication of FI942186A7 publication Critical patent/FI942186A7/fi
Publication of FI942186L publication Critical patent/FI942186L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06104—Dipeptides with the first amino acid being acidic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/12—Antivirals
    • A61P31/14—Antivirals for RNA viruses
    • A61P31/18—Antivirals for RNA viruses for HIV
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00—Drugs for immunological or allergic disorders
    • A61P37/02—Immunomodulators
    • A61P37/04—Immunostimulants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • C07K5/06086—Dipeptides with the first amino acid being basic
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Genetics & Genomics (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Immunology (AREA)
  • Virology (AREA)
  • Oncology (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Communicable Diseases (AREA)
  • AIDS & HIV (AREA)
  • Tropical Medicine & Parasitology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Polyurethanes Or Polyureas (AREA)
  • Agricultural Chemicals And Associated Chemicals (AREA)
FI942186A 1993-05-12 1994-05-11 Sytokiinituotantoa indusoivat uretaanit ja ureat FI942186L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US08/063,174 US5312831A (en) 1993-05-12 1993-05-12 Urethanes and ureas that induce cytokine production

Publications (3)

Publication Number Publication Date
FI942186A0 FI942186A0 (fi) 1994-05-11
FI942186A7 FI942186A7 (fi) 1994-11-13
FI942186L true FI942186L (fi) 1994-11-13

Family

ID=22047440

Family Applications (1)

Application Number Title Priority Date Filing Date
FI942186A FI942186L (fi) 1993-05-12 1994-05-11 Sytokiinituotantoa indusoivat uretaanit ja ureat

Country Status (26)

Country Link
US (6) US5312831A (cs)
EP (1) EP0652228B1 (cs)
JP (1) JP3583469B2 (cs)
KR (1) KR100296543B1 (cs)
CN (1) CN1094943C (cs)
AT (1) ATE144533T1 (cs)
AU (1) AU669064B2 (cs)
CA (1) CA2123261A1 (cs)
CZ (1) CZ290445B6 (cs)
DE (1) DE69400798T2 (cs)
DK (1) DK0652228T3 (cs)
ES (1) ES2094004T3 (cs)
FI (1) FI942186L (cs)
GR (1) GR3022253T3 (cs)
HU (1) HU219768B (cs)
IL (1) IL109602A (cs)
NO (1) NO311223B1 (cs)
NZ (1) NZ260507A (cs)
PH (1) PH30182A (cs)
PL (1) PL179984B1 (cs)
RU (1) RU2135515C1 (cs)
SG (1) SG43071A1 (cs)
SI (1) SI0652228T1 (cs)
SK (1) SK281120B6 (cs)
TW (1) TW380129B (cs)
ZA (1) ZA943266B (cs)

Families Citing this family (36)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE1007183A3 (fr) * 1993-06-18 1995-04-18 Solvay Ureines derivees d'alpha, omega-diaminoacides et procede pour leur preparation.
EP0809492A4 (en) * 1995-02-17 2007-01-24 Smithkline Beecham Corp IL-8 RECEPTOR ANTAGONISTS
US6005008A (en) * 1996-02-16 1999-12-21 Smithkline Beecham Corporation IL-8 receptor antagonists
US6211373B1 (en) 1996-03-20 2001-04-03 Smithkline Beecham Corporation Phenyl urea antagonists of the IL-8 receptor
US6262113B1 (en) 1996-03-20 2001-07-17 Smithkline Beecham Corporation IL-8 receptor antagonists
PL330850A1 (en) * 1996-06-27 1999-06-07 Smithkline Beecham Corp Antagonists of il-8 receptors
WO1997049286A1 (en) 1996-06-27 1997-12-31 Smithkline Beecham Corporation Il-8 receptor antagonists
WO1998006398A1 (en) * 1996-08-15 1998-02-19 Smithkline Beecham Corporation Il-8 receptor antagonists
US6492370B1 (en) 1998-03-26 2002-12-10 Santen Pharmaceutical Co., Ltd. Urea derivatives and pharmaceutical compositions thereof
US7465754B1 (en) 1999-09-15 2008-12-16 Wyeth Method of potentiating chemotherapy and treating solid tumors
IL163868A0 (en) * 2002-03-22 2005-12-18 Eisai Co Ltd Hermiasterlin derivatives and uses thereof
US7048922B2 (en) * 2002-05-29 2006-05-23 Demao Yang Stimulation of hematopoiesis by ex vivo activated immune cells
US7332158B2 (en) * 2002-05-29 2008-02-19 Demao Yang Compositions and treatments for myelosuppression by ex vivo activated immune cells
MY143477A (en) * 2002-10-29 2011-05-31 Smithkline Beecham Corp Il-8 receptor antagonists
US20060057121A1 (en) * 2004-09-10 2006-03-16 Demao Yang Compositions and treatments using ex vivo activated cells for myelosuppressed patients
ES2389680T3 (es) * 2006-04-21 2012-10-30 Glaxosmithkline Llc Antagonistas del receptor de IL-8
RU2008145871A (ru) * 2006-04-21 2010-05-27 Смитклайн Бичам Корпорейшн (US) Антагонисты рецептора il-8
PE20080943A1 (es) * 2006-06-23 2008-09-27 Smithkline Beecham Corp Sal toluenosulfonato de 4-{[6-cloro-3-({[(2-cloro-3-fluorofenil)amino]carbonil}amino)-2-hidroxifenil]sulfonil}-1-piperazinacarboxilato de 1,1-dimetiletilo como antagonista del receptor de il-8
WO2013149025A1 (en) * 2012-03-30 2013-10-03 Givaudan, S., A. N-acyl serine derivatives as food flavouring compounds
CA2868085C (en) 2012-03-30 2020-09-15 Harry Renes Improvements in or relating to organic compounds
BR112014023905B1 (pt) 2012-03-30 2021-07-13 Givaudan Sa Composições de sabor e comestíveis compreendendo derivados de metionina n-acilados e bebida calórica e não-calórica
EP2830440B1 (en) 2012-03-30 2019-03-20 Givaudan SA N-acyl-aminocyclopropyl carboxylic acids as food flavouring compounds
WO2013149022A1 (en) 2012-03-30 2013-10-03 Givaudan S.A. N-acyl proline derivatives as food flavouring compounds
CN104244734B (zh) 2012-03-30 2018-04-03 奇华顿股份有限公司 作为食品加香化合物的n‑酰化1‑氨基环烷基羧酸
EP2830438B1 (en) 2012-03-30 2019-09-04 Givaudan SA N-acyl derivatives of gamma amino-butyric acid as food flavouring compounds, powder compositions containing them
KR102045591B1 (ko) 2012-03-30 2019-12-02 지보당 에스아 식품 향미 화합물로서의 감마 아미노-부티르산 및 베타 알라닌의 n-아실 유도체
US10834943B2 (en) 2013-10-02 2020-11-17 Givaudan S.A. Organic compounds having taste-modifying properties
CN105636934B (zh) 2013-10-02 2019-03-29 奇华顿股份有限公司 N-酰化的2-氨基异丁酸化合物和包含它们的香味组合物
EP3057448B1 (en) 2013-10-02 2017-12-06 Givaudan S.A. Organic compounds having taste-modifying properties
US10834950B2 (en) 2013-10-02 2020-11-17 Givaudan S.A. Organic compounds
EP3057446B1 (en) 2013-10-02 2017-12-06 Givaudan S.A. Organic compounds having taste-modifying properties
GB201317424D0 (en) 2013-10-02 2013-11-13 Givaudan Sa Improvements in or relating to organic compounds
WO2015050535A1 (en) 2013-10-02 2015-04-09 Givaudan S.A. Organic compounds
CN105592720B (zh) 2013-10-02 2020-07-07 奇华顿股份有限公司 具有味道改进特性的有机化合物
CA3072735A1 (en) 2017-08-21 2019-02-28 Celgene Corporation Processes for the preparation of (s)-tert-butyl 4,5-diamino-5-oxopentanoate
CN109601739B (zh) * 2019-01-17 2022-10-14 河南湾流生物科技有限公司 一种复合氨基酸饲料添加剂及其制备方法

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB2033906B (en) * 1978-10-19 1982-12-01 Anvar Water-soluble compounds derived from extracts of streptomyces stimulosus process for their production and compositions containing them
US4349466A (en) * 1978-11-14 1982-09-14 Fujisawa Pharmaceutical Co Peptide, process for preparation thereof and use thereof
US4725582A (en) * 1978-11-14 1988-02-16 Fujisawa Pharmaceutical Company, Ltd. Peptide, process for preparation thereof and use thereof
FR2460290A1 (fr) * 1979-06-29 1981-01-23 Rhone Poulenc Ind Nouveaux tetra- ou pentapeptides, leur preparation et les medicaments qui les contiennent
ES8604609A1 (es) * 1985-07-02 1986-02-01 Uriach & Cia Sa J Procedimiento para la obtencion de la 1-(n-(1(r,s)-(etoxi- carbonil)-3-fenilpropil)-l-alanil)-l-prolina
WO1993005780A1 (en) * 1991-09-27 1993-04-01 Board Of Regents, The University Of Texas System Amino acids containing parenteral formulations for the treatment of hypotension and related pathologies

Also Published As

Publication number Publication date
RU2135515C1 (ru) 1999-08-27
KR100296543B1 (ko) 2001-11-22
CA2123261A1 (en) 1994-11-13
FI942186A7 (fi) 1994-11-13
NO941786L (no) 1994-11-14
NZ260507A (en) 1996-02-27
SK281120B6 (sk) 2000-12-11
IL109602A (en) 2000-06-01
SI0652228T1 (en) 1997-10-31
HU219768B (hu) 2001-07-30
NO941786D0 (no) 1994-05-11
GR3022253T3 (en) 1997-04-30
US5658945A (en) 1997-08-19
EP0652228A1 (en) 1995-05-10
DE69400798D1 (de) 1996-11-28
FI942186A0 (fi) 1994-05-11
HUT67038A (en) 1995-01-30
US5602275A (en) 1997-02-11
TW380129B (en) 2000-01-21
DK0652228T3 (da) 1996-11-25
AU669064B2 (en) 1996-05-23
DE69400798T2 (de) 1997-03-13
PL179984B1 (pl) 2000-11-30
HU9401444D0 (en) 1994-08-29
US5545662A (en) 1996-08-13
SK49194A3 (en) 1995-02-08
CZ290445B6 (cs) 2002-07-17
US5312831A (en) 1994-05-17
ES2094004T3 (es) 1997-01-01
US5616612A (en) 1997-04-01
CN1094943C (zh) 2002-11-27
US5633280A (en) 1997-05-27
CZ98194A3 (en) 1994-12-15
PH30182A (en) 1997-01-21
ZA943266B (en) 1995-01-12
SG43071A1 (en) 1997-10-17
JP3583469B2 (ja) 2004-11-04
ATE144533T1 (de) 1996-11-15
IL109602A0 (en) 1994-08-26
JPH07179414A (ja) 1995-07-18
EP0652228B1 (en) 1996-10-23
AU6304394A (en) 1994-11-17
CN1100413A (zh) 1995-03-22
NO311223B1 (no) 2001-10-29

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