FI931085L - Antitumoerkompositioner och behandlingsmetoder - Google Patents

Antitumoerkompositioner och behandlingsmetoder Download PDF

Info

Publication number
FI931085L
FI931085L FI931085A FI931085A FI931085L FI 931085 L FI931085 L FI 931085L FI 931085 A FI931085 A FI 931085A FI 931085 A FI931085 A FI 931085A FI 931085 L FI931085 L FI 931085L
Authority
FI
Finland
Prior art keywords
behandlingsmetoder
antitumoerkompositioner
och
och behandlingsmetoder
antitumoerkompositioner och
Prior art date
Application number
FI931085A
Other languages
English (en)
Finnish (fi)
Other versions
FI931085A7 (fi
FI931085A0 (fi
Inventor
Fariborz Mohamadi
Michael Marriott Spees
Original Assignee
Lilly Co Eli
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lilly Co Eli filed Critical Lilly Co Eli
Publication of FI931085A0 publication Critical patent/FI931085A0/fi
Publication of FI931085A7 publication Critical patent/FI931085A7/fi
Publication of FI931085L publication Critical patent/FI931085L/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D307/00—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77—Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/78—Benzo [b] furans; Hydrogenated benzo [b] furans
    • C07D307/79—Benzo [b] furans; Hydrogenated benzo [b] furans with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to carbon atoms of the hetero ring
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/04—Indoles; Hydrogenated indoles
    • C07D209/30—Indoles; Hydrogenated indoles with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, directly attached to carbon atoms of the hetero ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/50—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom condensed with carbocyclic rings or ring systems
    • C07D333/52—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes
    • C07D333/62—Benzo[b]thiophenes; Hydrogenated benzo[b]thiophenes with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the hetero ring

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Furan Compounds (AREA)
  • Indole Compounds (AREA)
FI931085A 1992-03-13 1993-03-11 Antitumoerkompositioner och behandlingsmetoder FI931085L (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
US07/850,531 US5169860A (en) 1992-03-13 1992-03-13 Antitumor compositions and methods of treatment

Publications (3)

Publication Number Publication Date
FI931085A0 FI931085A0 (fi) 1993-03-11
FI931085A7 FI931085A7 (fi) 1993-09-14
FI931085L true FI931085L (fi) 1993-09-14

Family

ID=25308394

Family Applications (1)

Application Number Title Priority Date Filing Date
FI931085A FI931085L (fi) 1992-03-13 1993-03-11 Antitumoerkompositioner och behandlingsmetoder

Country Status (19)

Country Link
US (1) US5169860A (enExample)
EP (1) EP0560554A2 (enExample)
JP (1) JPH0649052A (enExample)
KR (1) KR930019655A (enExample)
CN (1) CN1076447A (enExample)
AU (2) AU662605B2 (enExample)
BR (1) BR9301137A (enExample)
CA (1) CA2091207A1 (enExample)
CZ (1) CZ36893A3 (enExample)
FI (1) FI931085L (enExample)
HU (1) HUT63830A (enExample)
IL (1) IL104981A0 (enExample)
MX (1) MX9301296A (enExample)
MY (1) MY111178A (enExample)
NO (1) NO930891L (enExample)
NZ (1) NZ247083A (enExample)
TW (1) TW215083B (enExample)
YU (1) YU16893A (enExample)
ZA (1) ZA931645B (enExample)

Families Citing this family (33)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US5254582A (en) * 1992-02-05 1993-10-19 Eli Lilly And Company Antitumor compositions and methods
CA2110524A1 (en) * 1992-12-10 1994-06-11 Gerald Burr Grindey Antitumor compositions and methods of treatment
US5270329A (en) * 1992-12-10 1993-12-14 Eli Lilly And Company Antitumor compositions and methods of treatment
ZA941500B (en) * 1993-03-10 1995-09-04 Lilly Co Eli Antitumor compositions and methods of treatment
US5529999A (en) * 1994-03-04 1996-06-25 Eli Lilly And Company Antitumor compositions and methods of treatment
US5629425A (en) * 1994-09-19 1997-05-13 Eli Lilly And Company Haloalkyl hemisolvates of 6-hydroxy-2-(4-hydroxyphenyl)-3-[4-piperidinoethoxy)-benzoyl]benzo[b]thiophene
CO4410191A1 (es) 1994-09-19 1997-01-09 Lilly Co Eli SINTESIS DE 3-[4-(2-AMINOETOXI)BENZOIL]-2-ARIL-6- HIDROXIBENZO [b] TIOFENOS
US5863936A (en) * 1995-04-18 1999-01-26 Geron Corporation Telomerase inhibitors
EP0888331A4 (en) * 1996-03-19 2001-05-23 Lilly Co Eli SYNTHESIS OF 3- [4- (2-AMINOETHOXY) BENZOYL] -2-ARYL-6-HYDROXY-BENZO [b] THIOPHENES
EP1021437B1 (en) * 1996-08-22 2001-11-14 Dong Wha Pharmaceutical Industrial Co. Ltd. Arylsulfonylimidazolone derivatives as an antitumor agent
EP0929540A4 (en) * 1996-10-04 2001-12-12 Lilly Co Eli ANTI-TUMOR COMPOSITIONS AND THERAPEUTIC METHODS
JP2000247949A (ja) * 1999-02-26 2000-09-12 Eisai Co Ltd スルホンアミド含有インドール化合物
ES2156550B1 (es) * 1999-04-19 2002-02-01 Univ Navarra Publica Derivados de benzo(b) tiofenosulfonamida-1,1-dioxido y su uso como agentes antineoplasicos.
JP4505876B2 (ja) * 1999-05-25 2010-07-21 東ソー株式会社 ４−ハロベンゾフラン誘導体及びその製造方法
TWI281916B (en) * 2001-10-25 2007-06-01 Lilly Co Eli Antitumor compounds and methods
US20050119318A1 (en) * 2003-10-31 2005-06-02 Hudyma Thomas W. Inhibitors of HCV replication
CA2707161C (en) * 2007-11-28 2016-08-16 Sequoia Pharmaceuticals, Inc. Compositions and methods for inhibiting cytochrome p450 2d6
KR101300702B1 (ko) * 2011-01-20 2013-08-26 대우조선해양 주식회사 탈가스 장치
CN103450149B (zh) * 2012-06-01 2015-10-14 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物及其制备方法和用途
CN104564805B (zh) * 2013-10-29 2017-11-10 海尔集团公司 一种离心风机的扇叶结构、离心风机及嵌入式空调内机
RS60048B1 (sr) 2015-02-16 2020-04-30 Univ Queensland Sulfoniluree i srodna jedinjenja i njihova upotreba
WO2017184623A1 (en) 2016-04-18 2017-10-26 Ifm Therapeutics, Inc Compounds and compositions for treating conditions associated with nlrp activity
EP3661925B1 (en) 2017-07-07 2021-11-24 Inflazome Limited Novel sulfonamide carboxamide compounds
WO2019023147A1 (en) 2017-07-24 2019-01-31 IFM Tre, Inc. COMPOUNDS AND COMPOSITIONS FOR THE TREATMENT OF PATHOLOGICAL CONDITIONS ASSOCIATED WITH NLRP ACTIVITY
US11542255B2 (en) 2017-08-15 2023-01-03 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
BR112020003014A2 (pt) 2017-08-15 2020-07-28 Inflazome Limited sulfonilureias e sulfoniltioureias como inibidores de vnlrp3
US11926600B2 (en) 2017-08-15 2024-03-12 Inflazome Limited Sulfonylureas and sulfonylthioureas as NLRP3 inhibitors
US12012392B2 (en) 2017-11-09 2024-06-18 Inflazome Limited Sulfonamide carboxamide compounds
WO2019092171A1 (en) 2017-11-09 2019-05-16 Inflazome Limited Novel sulfonamide carboxamide compounds
US11905252B2 (en) 2018-03-02 2024-02-20 Inflazome Limited Compounds
CN113056451A (zh) * 2018-10-24 2021-06-29 诺华股份有限公司 用于治疗与nlrp活性相关的病症的化合物和组合物
CN109384764B (zh) * 2018-12-12 2021-09-03 中国科学院上海有机化学研究所 苯基噻吩磺酰胺类化合物、药物组合物、其制备方法和应用
WO2022022646A1 (zh) * 2020-07-29 2022-02-03 南京明德新药研发有限公司 含硒五元杂芳环化合物

Family Cites Families (14)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3083207A (en) * 1963-03-26 Indolinesulfonylureas
DE1144259B (de) * 1956-05-29 1963-02-28 Hoechst Ag Verfahren zur Herstellung von Sulfonylharnstoffen
US3097242A (en) * 1960-06-29 1963-07-09 Olin Mathieson Hydrindene sulfonylureas
DE1240866B (de) * 1961-06-29 1967-05-24 Heyden Chem Fab Verfahren zur Herstellung von Indolin-6-sulfonylharnstoffen
US3102121A (en) * 1961-06-29 1963-08-27 Olin Mathieson Novel cumaransulfonylureas and 2,3-dihydrothionaphthenesulfonylureas
BE634577A (enExample) * 1962-04-11
US3849110A (en) * 1963-01-07 1974-11-19 Lilly Co Eli Herbicidal method employing aryl-sulfonylureas or salts thereof
US3736122A (en) * 1969-04-10 1973-05-29 C Tung Method of controlling plant growth
IL69621A0 (en) * 1982-09-02 1983-12-30 Duphar Int Res Pharmaceutical compositions having antitumor activity,comprising certain phenylurea derivatives
CA1208561A (en) * 1984-01-19 1986-07-29 Marius S. Brouwer Pharmaceutical compositions containing benzoylurea compounds
US4845128A (en) * 1984-06-27 1989-07-04 Eli Lilly And Company N([(4-trifluoromethylphenyl)amino]carbonyl)benzene sulfonamides
IL80032A (en) * 1985-09-23 1992-07-15 Lilly Co Eli Anti-tumor phenyl-aminocarbonylsulfonamides,their preparation and pharmaceutical compositions containing them
CA1331464C (en) * 1987-05-12 1994-08-16 Eli Lilly And Company Anti-tumor method and compounds
NZ238911A (en) * 1990-07-17 1993-10-26 Lilly Co Eli Furyl, pyrrolyl and thienyl sulphonyl urea derivatives, pharmaceutical compositions and intermediates therefor

Also Published As

Publication number Publication date
FI931085A7 (fi) 1993-09-14
AU3519893A (en) 1993-09-16
EP0560554A3 (enExample) 1994-01-19
YU16893A (sh) 1996-07-24
MX9301296A (es) 1993-10-01
NZ247083A (en) 1995-09-26
HUT63830A (en) 1993-10-28
BR9301137A (pt) 1993-09-28
HU9300688D0 (en) 1993-05-28
AU662605B2 (en) 1995-09-07
US5169860A (en) 1992-12-08
MY111178A (en) 1999-09-30
IL104981A0 (en) 1993-07-08
KR930019655A (ko) 1993-10-18
TW215083B (enExample) 1993-10-21
ZA931645B (en) 1994-09-08
NO930891D0 (no) 1993-03-11
CZ36893A3 (en) 1994-04-13
EP0560554A2 (en) 1993-09-15
CN1076447A (zh) 1993-09-22
AU4028995A (en) 1996-02-15
JPH0649052A (ja) 1994-02-22
CA2091207A1 (en) 1993-09-14
NO930891L (no) 1993-09-14
FI931085A0 (fi) 1993-03-11

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