FI925766A7 - Substituerade bensimidazoler, foerfarande foer deras framstaellning och deras farmaceutiska anvaendning - Google Patents

Substituerade bensimidazoler, foerfarande foer deras framstaellning och deras farmaceutiska anvaendning Download PDF

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Publication number
FI925766A7
FI925766A7 FI925766A FI925766A FI925766A7 FI 925766 A7 FI925766 A7 FI 925766A7 FI 925766 A FI925766 A FI 925766A FI 925766 A FI925766 A FI 925766A FI 925766 A7 FI925766 A7 FI 925766A7
Authority
FI
Finland
Prior art keywords
deras
farmaceutiska
bensimidazoler
substituerade
anvaendning
Prior art date
Application number
FI925766A
Other languages
English (en)
Finnish (fi)
Other versions
FI925766A0 (fi
Inventor
Arne Elof Braendstroem
Per Lennart Lindberg
Gunnel Elisabeth Sunden
Original Assignee
Astra Ab
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Astra Ab filed Critical Astra Ab
Publication of FI925766A7 publication Critical patent/FI925766A7/fi
Publication of FI925766A0 publication Critical patent/FI925766A0/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D401/00Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00Drugs for disorders of the alimentary tract or the digestive system
    • A61P1/04Drugs for disorders of the alimentary tract or the digestive system for ulcers, gastritis or reflux esophagitis, e.g. antacids, inhibitors of acid secretion, mucosal protectants
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D405/00Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/14Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing three or more hetero rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Engineering & Computer Science (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Pyridine Compounds (AREA)
FI925766A 1990-06-20 1992-12-18 Substituerade bensimidazoler, foerfarande foer deras framstaellning och deras farmaceutiska anvaendning FI925766A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
SE9002206A SE9002206D0 (sv) 1990-06-20 1990-06-20 New compounds
PCT/SE1991/000415 WO1991019711A1 (en) 1990-06-20 1991-06-11 Substituted benzimidazoles, process for their preparation and their pharmaceutical use

Publications (2)

Publication Number Publication Date
FI925766A7 true FI925766A7 (fi) 1992-12-18
FI925766A0 FI925766A0 (fi) 1992-12-18

Family

ID=20379831

Family Applications (1)

Application Number Title Priority Date Filing Date
FI925766A FI925766A0 (fi) 1990-06-20 1992-12-18 Substituerade bensimidazoler, foerfarande foer deras framstaellning och deras farmaceutiska anvaendning

Country Status (27)

Country Link
EP (1) EP0535081A1 (enrdf_load_stackoverflow)
JP (1) JPH05507713A (enrdf_load_stackoverflow)
CN (1) CN1058212A (enrdf_load_stackoverflow)
AP (1) AP215A (enrdf_load_stackoverflow)
AU (1) AU649453B2 (enrdf_load_stackoverflow)
BG (1) BG97200A (enrdf_load_stackoverflow)
CA (1) CA2083714A1 (enrdf_load_stackoverflow)
CZ (1) CZ279772B6 (enrdf_load_stackoverflow)
FI (1) FI925766A0 (enrdf_load_stackoverflow)
HU (1) HUT62881A (enrdf_load_stackoverflow)
IE (1) IE912025A1 (enrdf_load_stackoverflow)
IL (1) IL98470A0 (enrdf_load_stackoverflow)
IS (1) IS3721A7 (enrdf_load_stackoverflow)
LT (2) LT3977B (enrdf_load_stackoverflow)
LV (1) LV10953A (enrdf_load_stackoverflow)
MA (1) MA22199A1 (enrdf_load_stackoverflow)
NO (1) NO924775L (enrdf_load_stackoverflow)
NZ (1) NZ238546A (enrdf_load_stackoverflow)
OA (1) OA09682A (enrdf_load_stackoverflow)
PT (1) PT98035A (enrdf_load_stackoverflow)
RO (1) RO110493B1 (enrdf_load_stackoverflow)
SE (1) SE9002206D0 (enrdf_load_stackoverflow)
TN (1) TNSN91049A1 (enrdf_load_stackoverflow)
TW (1) TW216418B (enrdf_load_stackoverflow)
WO (1) WO1991019711A1 (enrdf_load_stackoverflow)
YU (1) YU104191A (enrdf_load_stackoverflow)
ZA (2) ZA914296B (enrdf_load_stackoverflow)

Families Citing this family (30)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE9002043D0 (sv) * 1990-06-07 1990-06-07 Astra Ab Improved method for synthesis
SE9103776D0 (sv) * 1991-12-19 1991-12-19 Astra Ab New compounds
IS4232A (is) * 1993-12-06 1995-06-07 Astra Aktiebolag Súbstitúerað bensimidasól, aðferðir við framleiðslu þess og lyfjafræðileg notkun
SE504459C2 (sv) * 1994-07-15 1997-02-17 Astra Ab Förfarande för framställning av substituerade sulfoxider
SE9500422D0 (sv) * 1995-02-06 1995-02-06 Astra Ab New oral pharmaceutical dosage forms
SE9500478D0 (sv) * 1995-02-09 1995-02-09 Astra Ab New pharmaceutical formulation and process
SE9600070D0 (sv) 1996-01-08 1996-01-08 Astra Ab New oral pharmaceutical dosage forms
BR0017140A (pt) 2000-02-24 2004-05-25 Kopran Res Lab Ltd Derivados de benzimidazol anti-úlcera estáveis ácidos para administração oral
SE0101379D0 (sv) 2001-04-18 2001-04-18 Diabact Ab Komposition som hämmar utsöndring av magsyra
US8206741B2 (en) 2001-06-01 2012-06-26 Pozen Inc. Pharmaceutical compositions for the coordinated delivery of NSAIDs
IL164222A0 (en) 2002-04-09 2005-12-18 Flamel Tech Sa Oral pharmaceutical formulation in the form of aqueous suspension for modified release of active principle(s)
SE0203065D0 (sv) 2002-10-16 2002-10-16 Diabact Ab Gastric acid secretion inhibiting composition
ATE544447T1 (de) 2003-09-26 2012-02-15 Alza Corp Arzneistoffcoating mit hohem wirkstoffanteil sowie methoden zu dessen herstellung
TW200606163A (en) 2004-04-22 2006-02-16 Eisai Co Ltd Imidazopyridine compound
US8541026B2 (en) 2004-09-24 2013-09-24 Abbvie Inc. Sustained release formulations of opioid and nonopioid analgesics
US20070015782A1 (en) * 2005-04-15 2007-01-18 Eisai Co., Ltd. Benzimidazole compound
US9040564B2 (en) 2005-04-28 2015-05-26 Eisai R&D Management Co., Ltd. Stabilized composition
US7803817B2 (en) 2005-05-11 2010-09-28 Vecta, Ltd. Composition and methods for inhibiting gastric acid secretion
US7981908B2 (en) 2005-05-11 2011-07-19 Vecta, Ltd. Compositions and methods for inhibiting gastric acid secretion
WO2007122686A1 (ja) * 2006-04-14 2007-11-01 Eisai R & D Management Co., Ltd. ベンズイミダゾール化合物
CA2658804A1 (en) 2006-07-25 2008-01-31 Vecta Ltd. Compositions and methods for inhibiting gastric acid secretion using derivatives of small dicarboxylic acids in combination with ppi
EP2065379A4 (en) * 2006-10-13 2011-01-19 Eisai R&D Man Co Ltd BENZIMIDAZOLE HAVING INHIBITORY ACTIVITY OF GASTRIC ACID SECRETION
MX2011002515A (es) 2008-09-09 2011-04-07 Astrazeneca Ab Metodo de administracion de una composicion farmaceutica a un paciente que lo necesita.
AU2010263304A1 (en) 2009-06-25 2012-02-02 Astrazeneca Ab Method for treating a patient at risk for developing an NSAID-associated ulcer
EP2519229A2 (en) 2009-12-29 2012-11-07 Novartis AG New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080500A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
WO2011080502A2 (en) 2009-12-29 2011-07-07 Orexo Ab New pharmaceutical dosage form for the treatment of gastric acid-related disorders
EP2601947A1 (en) 2011-12-05 2013-06-12 Abo Bakr Mohammed Ali Al-Mehdar Fixed-dose combination for treatment of helicobacter pylori associated diseases
UA115139C2 (uk) 2011-12-28 2017-09-25 Поузен Інк. Спосіб доставки фармацевтичної композиції, яка містить омепразол й ацетилсаліцилову кислоту, пацієнту
US11370775B2 (en) * 2016-09-14 2022-06-28 Yufeng Jane Tseng Substituted benzimidazole derivatives as D-amino acid oxidase (DAAO) inhibitors

Family Cites Families (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
SE418966B (sv) 1974-02-18 1981-07-06 Haessle Ab Analogiforfarande for framstellning av foreningar med magsyrasekretionsinhiberande verkan
SE416649B (sv) 1974-05-16 1981-01-26 Haessle Ab Forfarande for framstellning av foreningar som paverkar magsyrasekretionen
IN148930B (enrdf_load_stackoverflow) 1977-09-19 1981-07-25 Hoffmann La Roche
SE7804231L (sv) 1978-04-14 1979-10-15 Haessle Ab Magsyrasekretionsmedel
US4359465A (en) 1980-07-28 1982-11-16 The Upjohn Company Methods for treating gastrointestinal inflammation
CH644116A5 (de) 1980-08-21 1984-07-13 Hoffmann La Roche Imidazolderivate.
SE8300736D0 (sv) 1983-02-11 1983-02-11 Haessle Ab Novel pharmacologically active compounds
SE8301182D0 (sv) 1983-03-04 1983-03-04 Haessle Ab Novel compounds
IL75400A (en) * 1984-06-16 1988-10-31 Byk Gulden Lomberg Chem Fab Dialkoxypyridine methyl(sulfinyl or sulfonyl)benzimidazoles,processes for the preparation thereof and pharmaceutical compositions containing the same
AU568441B2 (en) * 1984-09-24 1987-12-24 Upjohn Company, The 2-(pyridylalkenesulfinyl) benzimidazole derivatives
IL76839A (en) * 1984-10-31 1988-08-31 Byk Gulden Lomberg Chem Fab Picoline derivatives,processes for the preparation thereof and pharmaceutical compositions containing the same
US4738975A (en) 1985-07-02 1988-04-19 Takeda Chemical Industries, Ltd. Pyridine derivatives, and use as anti-ulcer agents
SE8505112D0 (sv) * 1985-10-29 1985-10-29 Haessle Ab Novel pharmacological compounds
NZ234564A (en) 1986-11-21 1991-04-26 Haessle Ab 1-substituted benzimidazoles and pharmaceutical compositions
DE3722810A1 (de) * 1987-07-10 1989-01-19 Hoechst Ag Substituierte benzimidazole, verfahren zu deren herstellung, diese enthaltende pharmazeutische zubereitungen und deren verwendung
KR890701580A (ko) * 1987-10-30 1989-12-21 앤더스 베딘 골(骨)손실에 관련된 질병 치료용 2-피리디닐메틸(술피닐 또는 티오) 벤즈이미다졸
WO1989005299A1 (en) * 1987-12-11 1989-06-15 Byk Gulden Lomberg Chemische Fabrik Gmbh Novel benzimidazole derivatives
JPH03504497A (ja) * 1988-05-25 1991-10-03 ビイク グルデン ロンベルク ヒエーミツシエ フアブリーク ゲゼルシヤフト ミツト ベシユレンクテル ハフツング 新規フルオルアルコキシ化合物

Also Published As

Publication number Publication date
CS189491A3 (en) 1992-04-15
AP9100285A0 (en) 1991-07-31
LTIP1712A (en) 1995-08-25
HUT62881A (en) 1993-06-28
NO924775D0 (no) 1992-12-10
CN1058212A (zh) 1992-01-29
ZA914296B (en) 1992-03-25
MA22199A1 (fr) 1992-04-01
EP0535081A1 (en) 1993-04-07
PT98035A (pt) 1992-03-31
AU8009791A (en) 1992-01-07
BG97200A (bg) 1993-12-24
LT3952B (en) 1996-05-27
AP215A (en) 1992-09-02
ZA914297B (en) 1992-03-25
NO924775L (no) 1992-12-10
TW216418B (enrdf_load_stackoverflow) 1993-11-21
LT3977B (en) 1996-06-25
AU649453B2 (en) 1994-05-26
NZ238546A (en) 1994-03-25
IS3721A7 (is) 1991-12-21
IL98470A0 (en) 1992-07-15
JPH05507713A (ja) 1993-11-04
RO110493B1 (ro) 1996-01-30
SE9002206D0 (sv) 1990-06-20
CZ279772B6 (cs) 1995-06-14
HU9204033D0 (en) 1993-03-29
YU104191A (sh) 1994-01-20
WO1991019711A1 (en) 1991-12-26
TNSN91049A1 (fr) 1992-10-25
LV10953A (lv) 1995-12-20
CA2083714A1 (en) 1991-12-21
OA09682A (en) 1993-05-15
IE912025A1 (en) 1992-01-01
LTIP1713A (en) 1995-08-25
FI925766A0 (fi) 1992-12-18

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Legal Events

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