FI913477A - Förfarande för framställning av nya terapeutiskt användbara imidazol-fenyl-imidazo/1,2-a/pyridin- och imidazol-fenyl-imidazo/1,2-a/pyrimidinderivat - Google Patents
Förfarande för framställning av nya terapeutiskt användbara imidazol-fenyl-imidazo/1,2-a/pyridin- och imidazol-fenyl-imidazo/1,2-a/pyrimidinderivat Download PDFInfo
- Publication number
- FI913477A FI913477A FI913477A FI913477A FI913477A FI 913477 A FI913477 A FI 913477A FI 913477 A FI913477 A FI 913477A FI 913477 A FI913477 A FI 913477A FI 913477 A FI913477 A FI 913477A
- Authority
- FI
- Finland
- Prior art keywords
- imidazo
- phenyl
- imidazole
- pyridine
- preparation
- Prior art date
Links
- JUJWROOIHBZHMG-UHFFFAOYSA-N Pyridine Chemical compound C1=CC=NC=C1 JUJWROOIHBZHMG-UHFFFAOYSA-N 0.000 title 2
- UMJSCPRVCHMLSP-UHFFFAOYSA-N pyridine Natural products COC1=CC=CN=C1 UMJSCPRVCHMLSP-UHFFFAOYSA-N 0.000 title 1
- 229940083082 pyrimidine derivative acting on arteriolar smooth muscle Drugs 0.000 title 1
- 150000003230 pyrimidines Chemical class 0.000 title 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
- C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
- C07D403/10—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
- A61P1/16—Drugs for disorders of the alimentary tract or the digestive system for liver or gallbladder disorders, e.g. hepatoprotective agents, cholagogues, litholytics
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P13/00—Drugs for disorders of the urinary system
- A61P13/12—Drugs for disorders of the urinary system of the kidneys
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/08—Vasodilators for multiple indications
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/10—Drugs for disorders of the cardiovascular system for treating ischaemic or atherosclerotic diseases, e.g. antianginal drugs, coronary vasodilators, drugs for myocardial infarction, retinopathy, cerebrovascula insufficiency, renal arteriosclerosis
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P9/00—Drugs for disorders of the cardiovascular system
- A61P9/12—Antihypertensives
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/90—Carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D413/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms
- C07D413/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings
- C07D413/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and oxygen atoms as the only ring hetero atoms containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
- C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
- C07D417/10—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings linked by a carbon chain containing aromatic rings
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D513/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00
- C07D513/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for in groups C07D463/00, C07D477/00 or C07D499/00 - C07D507/00 in which the condensed system contains two hetero rings
- C07D513/04—Ortho-condensed systems
Landscapes
- Organic Chemistry (AREA)
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Bioinformatics & Cheminformatics (AREA)
- Engineering & Computer Science (AREA)
- General Health & Medical Sciences (AREA)
- Veterinary Medicine (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- General Chemical & Material Sciences (AREA)
- Pharmacology & Pharmacy (AREA)
- Life Sciences & Earth Sciences (AREA)
- Animal Behavior & Ethology (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Public Health (AREA)
- Medicinal Chemistry (AREA)
- Cardiology (AREA)
- Heart & Thoracic Surgery (AREA)
- Urology & Nephrology (AREA)
- Vascular Medicine (AREA)
- Hospice & Palliative Care (AREA)
- Gastroenterology & Hepatology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
- Nitrogen Condensed Heterocyclic Rings (AREA)
- Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
Applications Claiming Priority (2)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
DE4023215 | 1990-07-21 | ||
DE4023215A DE4023215A1 (de) | 1990-07-21 | 1990-07-21 | Substituierte azole, verfahren zu deren herstellung, sie enthaltende mittel und deren verwendung |
Publications (4)
Publication Number | Publication Date |
---|---|
FI913477A0 FI913477A0 (sv) | 1991-07-18 |
FI913477A true FI913477A (sv) | 1992-01-22 |
FI95254B FI95254B (sv) | 1995-09-29 |
FI95254C FI95254C (sv) | 1996-01-10 |
Family
ID=6410744
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI913477A FI95254C (sv) | 1990-07-21 | 1991-07-18 | Förfarande för framställning av nya terapeutiskt användbara imidazol-fenyl-imidazo/1,2-a/pyridin- och imidazol-fenyl-imidazo/1,2-a/pyrimidinderivat |
Country Status (19)
Country | Link |
---|---|
US (1) | US5225414A (sv) |
EP (1) | EP0468372A3 (sv) |
JP (1) | JPH04234388A (sv) |
KR (1) | KR920002598A (sv) |
CN (1) | CN1031404C (sv) |
AU (1) | AU648323B2 (sv) |
CA (1) | CA2047467A1 (sv) |
CZ (1) | CZ280584B6 (sv) |
DE (1) | DE4023215A1 (sv) |
FI (1) | FI95254C (sv) |
HU (2) | HU212420B (sv) |
IE (1) | IE912550A1 (sv) |
IL (1) | IL98898A (sv) |
NO (1) | NO179283C (sv) |
NZ (1) | NZ239039A (sv) |
PT (1) | PT98369B (sv) |
RU (1) | RU2047604C1 (sv) |
YU (1) | YU126291A (sv) |
ZA (1) | ZA915683B (sv) |
Families Citing this family (35)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DE4010797A1 (de) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
DE4036706A1 (de) * | 1990-11-17 | 1992-05-21 | Hoechst Ag | Verfahren zur behandlung der cardialen sowie der vasculaeren hypertrophie und hyperplasie |
US5616599A (en) * | 1991-02-21 | 1997-04-01 | Sankyo Company, Limited | Angiotensin II antagosist 1-biphenylmethylimidazole compounds and their therapeutic use |
US5177074A (en) * | 1991-03-26 | 1993-01-05 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating a substituted thiophene or furan |
US5252574A (en) * | 1991-04-26 | 1993-10-12 | Merck & Co., Inc. | Angiotensin II antagonists incorporating a substituted thiophene or furan |
US5198438A (en) * | 1991-05-07 | 1993-03-30 | Merck & Co., Inc. | Angiotensin ii antagonists incorporating a substituted thiophene or furan |
US5364869A (en) * | 1992-03-09 | 1994-11-15 | Abbott Laboratories | Heterocycle-substituted benzyaminopyridine angiotensin II receptor antagonists |
JP3501484B2 (ja) * | 1992-12-17 | 2004-03-02 | 三共株式会社 | ビフェニル誘導体 |
US5338740A (en) * | 1993-07-13 | 1994-08-16 | Pfizer Inc. | Angiotensin II receptor antagonists |
US5677302A (en) * | 1996-02-26 | 1997-10-14 | Apotex Inc. | Thiadiazole compounds useful as proton pump inhibitors |
DE19645313A1 (de) | 1996-11-04 | 1998-05-07 | Basf Ag | Substituierte 3-Benzylpyrazole |
SE9903028D0 (sv) | 1999-08-27 | 1999-08-27 | Astra Ab | New use |
US7253165B2 (en) * | 1999-09-14 | 2007-08-07 | Aventis Pharmaceuticals Inc. | Benzisoxazolyl-, pyridoisoxazolyl-and benzthienyl-phenoxy derivatives useful as D4 antagonists |
US7091199B1 (en) | 1999-09-14 | 2006-08-15 | Aventis Pharmaceuticals Inc. | Thienoisoxazole phenoxy unsubstituted ethyl and propyl derivatives useful as d4 antagonists |
US7125903B1 (en) | 1999-09-14 | 2006-10-24 | Aventis Pharmaceuticals Inc. | Thienoisoxazolyl-and thienylpyrrazolyl-phenoxy substituted propyl derivatives useful as D4 antagonists |
GB0016787D0 (en) | 2000-07-07 | 2000-08-30 | Pfizer Ltd | Compounds useful in therapy |
CN1678608A (zh) * | 2002-07-02 | 2005-10-05 | 先灵公司 | 新的神经肽yy5受体拮抗剂 |
US20070054948A1 (en) * | 2004-09-02 | 2007-03-08 | Lilach Hedvati | Purification of olmesartan medoxomil |
KR100953878B1 (ko) * | 2004-09-02 | 2010-04-22 | 테바 파마슈티컬 인더스트리즈 리미티드 | 올메살탄 메독소밀의 정제 |
ES2582945T3 (es) | 2005-04-12 | 2016-09-16 | Vicore Pharma Ab | Nuevos agonistas bicíclicos de angiotensina II |
AU2006235706B2 (en) | 2005-04-12 | 2012-03-08 | Vicore Pharma Ab | New tricyclic angiotensin II agonists |
KR101429484B1 (ko) | 2005-04-12 | 2014-08-13 | 바이코어 파마 아베 | 신규한 트리시클릭 안지오텐신 ⅱ 아고니스트 |
US8969514B2 (en) | 2007-06-04 | 2015-03-03 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase useful for the treatment of hypercholesterolemia, atherosclerosis, coronary heart disease, gallstone, obesity and other cardiovascular diseases |
DK2170930T3 (da) | 2007-06-04 | 2012-11-05 | Synergy Pharmaceuticals Inc | Agonister af guanylatcyclase, anvendelige til behandlingen af gastrointestinale sygdomme, inflammation, cancer og andre sygdomme |
EP2170337A4 (en) | 2007-06-28 | 2013-12-18 | Abbvie Inc | NEW TRIAZOLOPYRIDAZINE |
JP2011522828A (ja) | 2008-06-04 | 2011-08-04 | シナジー ファーマシューティカルズ インコーポレイテッド | 胃腸障害、炎症、癌、およびその他の障害の治療のために有用なグアニル酸シクラーゼのアゴニスト |
ES2624828T3 (es) | 2008-07-16 | 2017-07-17 | Synergy Pharmaceuticals Inc. | Agonistas de la guanilato ciclasa útiles para el tratamiento de trastornos gastrointestinales, inflamación, cáncer y otros |
IN2012DN04917A (sv) | 2009-11-05 | 2015-09-25 | Univ Notre Dame Du Lac | |
US9616097B2 (en) | 2010-09-15 | 2017-04-11 | Synergy Pharmaceuticals, Inc. | Formulations of guanylate cyclase C agonists and methods of use |
WO2012174164A2 (en) | 2011-06-15 | 2012-12-20 | Metabolex, Inc. | Agonists of gpr131 and uses thereof |
US9593109B2 (en) | 2011-08-26 | 2017-03-14 | Cymabay Therapeutics, Inc. | Bicyclic agonists of GPR131 and uses thereof |
US9708367B2 (en) | 2013-03-15 | 2017-07-18 | Synergy Pharmaceuticals, Inc. | Agonists of guanylate cyclase and their uses |
AU2014235209B2 (en) | 2013-03-15 | 2018-06-14 | Bausch Health Ireland Limited | Guanylate cyclase receptor agonists combined with other drugs |
KR102272746B1 (ko) | 2013-06-05 | 2021-07-08 | 보슈 헬스 아일랜드 리미티드 | 구아닐레이트 사이클라제 c의 초순수 작용제, 및 이의 제조 및 사용 방법 |
JP7055378B2 (ja) | 2015-09-17 | 2022-04-18 | ユニバーシティ・オブ・ノートル・ダム・デュ・ラック | マイコバクテリア感染症に対して有用なベンジルアミン含有複素環化合物及び組成物 |
Family Cites Families (9)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
CH522432A (de) * | 1967-02-07 | 1972-06-30 | Ciba Geigy Ag | Verwendung von v-Triazolen als Schutzmittel für nichttextile organische Substrate gegen UV-Strahlen |
DK151884C (da) * | 1979-03-07 | 1988-06-13 | Pfizer | Analogifremgangsmaade til fremstilling af 3-(1-imidazolylalkyl)indolderivater eller farmaceutisk acceptable syreadditionssalte deraf |
DE3310197A1 (de) * | 1983-03-21 | 1984-09-27 | A. Nattermann & Cie GmbH, 5000 Köln | Substituierte 3-mercapto-pyridazine und deren 3-alkylthioderivate sowie verfahren zu ihrer herstellung |
CA1334092C (en) * | 1986-07-11 | 1995-01-24 | David John Carini | Angiotensin ii receptor blocking imidazoles |
DE3702758A1 (de) * | 1987-01-30 | 1988-09-29 | Hoechst Ag | Substituierte 3-phenyl-7h-thiazolo (3,2-b) (1,2,4) triazin-7-one, verfahren zu ihrer herstellung, die sie enthaltenden arzneimittel und ihre verwendung, sowie einige bei der herstellung der genannten verbindungen gebildete zwischenprodukte |
US5015651A (en) * | 1988-01-07 | 1991-05-14 | E. I. Du Pont De Nemours And Company | Treatment of hypertension with 1,2,4-angiotensin II antagonists |
IE64514B1 (en) * | 1989-05-23 | 1995-08-09 | Zeneca Ltd | Azaindenes |
IE70593B1 (en) * | 1989-09-29 | 1996-12-11 | Eisai Co Ltd | Biphenylmethane derivative the use of it and pharmacological compositions containing same |
DE4010797A1 (de) * | 1990-04-04 | 1991-10-10 | Hoechst Ag | Substituierte azole, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung |
-
1990
- 1990-07-21 DE DE4023215A patent/DE4023215A1/de not_active Withdrawn
-
1991
- 1991-07-17 YU YU126291A patent/YU126291A/sh unknown
- 1991-07-18 PT PT98369A patent/PT98369B/pt not_active IP Right Cessation
- 1991-07-18 FI FI913477A patent/FI95254C/sv active
- 1991-07-18 EP EP19910112045 patent/EP0468372A3/de not_active Withdrawn
- 1991-07-18 US US07/731,989 patent/US5225414A/en not_active Expired - Fee Related
- 1991-07-19 IL IL9889891A patent/IL98898A/en active IP Right Grant
- 1991-07-19 CZ CS912259A patent/CZ280584B6/cs unknown
- 1991-07-19 NZ NZ239039A patent/NZ239039A/en unknown
- 1991-07-19 HU HU912432A patent/HU212420B/hu not_active IP Right Cessation
- 1991-07-19 IE IE255091A patent/IE912550A1/en unknown
- 1991-07-19 ZA ZA915683A patent/ZA915683B/xx unknown
- 1991-07-19 AU AU81129/91A patent/AU648323B2/en not_active Ceased
- 1991-07-19 JP JP3203665A patent/JPH04234388A/ja active Pending
- 1991-07-19 NO NO912848A patent/NO179283C/no unknown
- 1991-07-19 RU SU915001058A patent/RU2047604C1/ru active
- 1991-07-19 CA CA002047467A patent/CA2047467A1/en not_active Abandoned
- 1991-07-20 KR KR1019910012470A patent/KR920002598A/ko not_active Application Discontinuation
- 1991-07-20 CN CN91104891A patent/CN1031404C/zh not_active Expired - Fee Related
-
1995
- 1995-05-09 HU HU95P/P00124P patent/HU211918A9/hu unknown
Also Published As
Publication number | Publication date |
---|---|
FI95254B (sv) | 1995-09-29 |
KR920002598A (ko) | 1992-02-28 |
HU912432D0 (en) | 1991-12-30 |
YU126291A (sh) | 1994-06-24 |
CN1058406A (zh) | 1992-02-05 |
NO912848D0 (no) | 1991-07-19 |
IE912550A1 (en) | 1992-01-29 |
NO179283B (no) | 1996-06-03 |
NO179283C (no) | 1996-09-11 |
ZA915683B (en) | 1992-04-29 |
AU648323B2 (en) | 1994-04-21 |
FI95254C (sv) | 1996-01-10 |
AU8112991A (en) | 1992-01-23 |
HUT59145A (en) | 1992-04-28 |
HU211918A9 (en) | 1996-01-29 |
HU212420B (en) | 1996-06-28 |
PT98369B (pt) | 1999-01-29 |
NO912848L (no) | 1992-01-22 |
US5225414A (en) | 1993-07-06 |
RU2047604C1 (ru) | 1995-11-10 |
EP0468372A2 (de) | 1992-01-29 |
JPH04234388A (ja) | 1992-08-24 |
IL98898A0 (en) | 1992-07-15 |
EP0468372A3 (en) | 1992-05-06 |
CS225991A3 (en) | 1992-06-17 |
PT98369A (pt) | 1992-05-29 |
FI913477A0 (sv) | 1991-07-18 |
NZ239039A (en) | 1994-05-26 |
IL98898A (en) | 1995-11-27 |
CZ280584B6 (cs) | 1996-02-14 |
CN1031404C (zh) | 1996-03-27 |
CA2047467A1 (en) | 1992-01-22 |
DE4023215A1 (de) | 1992-01-23 |
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