FI905475A0 - Menetelmä farmaseuttisesti vaikuttavan puriinijohdannaisen valmistamiseksi - Google Patents
Menetelmä farmaseuttisesti vaikuttavan puriinijohdannaisen valmistamiseksiInfo
- Publication number
- FI905475A0 FI905475A0 FI905475A FI905475A FI905475A0 FI 905475 A0 FI905475 A0 FI 905475A0 FI 905475 A FI905475 A FI 905475A FI 905475 A FI905475 A FI 905475A FI 905475 A0 FI905475 A0 FI 905475A0
- Authority
- FI
- Finland
- Prior art keywords
- hydroxy
- amino
- hydrogen
- compounds
- chem
- Prior art date
Links
- 238000004519 manufacturing process Methods 0.000 title abstract 2
- 125000000561 purinyl group Chemical class N1=C(N=C2N=CNC2=C1)* 0.000 title 1
- 150000001875 compounds Chemical class 0.000 abstract 4
- 229910052739 hydrogen Inorganic materials 0.000 abstract 4
- 239000001257 hydrogen Substances 0.000 abstract 4
- 125000004435 hydrogen atom Chemical class [H]* 0.000 abstract 4
- 125000004356 hydroxy functional group Chemical group O* 0.000 abstract 3
- 125000002924 primary amino group Chemical group [H]N([H])* 0.000 abstract 3
- RTZKZFJDLAIYFH-UHFFFAOYSA-N Diethyl ether Chemical compound CCOCC RTZKZFJDLAIYFH-UHFFFAOYSA-N 0.000 abstract 2
- -1 hydroxy, mercapto Chemical class 0.000 abstract 2
- 238000000034 method Methods 0.000 abstract 2
- 208000030507 AIDS Diseases 0.000 abstract 1
- 125000001309 chloro group Chemical group Cl* 0.000 abstract 1
- 239000003814 drug Substances 0.000 abstract 1
- 125000004185 ester group Chemical group 0.000 abstract 1
- 125000001153 fluoro group Chemical group F* 0.000 abstract 1
- 239000008194 pharmaceutical composition Substances 0.000 abstract 1
- 150000003839 salts Chemical class 0.000 abstract 1
- 230000009385 viral infection Effects 0.000 abstract 1
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D473/00—Heterocyclic compounds containing purine ring systems
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
- A61P31/12—Antivirals
- A61P31/20—Antivirals for DNA viruses
- A61P31/22—Antivirals for DNA viruses for herpes viruses
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6561—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
- C07F9/65616—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system having three or more than three double bonds between ring members or between ring members and non-ring members, e.g. purine or analogs
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07F—ACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
- C07F9/00—Compounds containing elements of Groups 5 or 15 of the Periodic Table
- C07F9/02—Phosphorus compounds
- C07F9/547—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
- C07F9/6564—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms
- C07F9/6571—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms
- C07F9/657163—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom
- C07F9/657181—Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom having phosphorus atoms, with or without nitrogen, oxygen, sulfur, selenium or tellurium atoms, as ring hetero atoms having phosphorus and oxygen atoms as the only ring hetero atoms the ring phosphorus atom being bound to at least one carbon atom the ring phosphorus atom and, at least, one ring oxygen atom being part of a (thio)phosphonic acid derivative
Landscapes
- Chemical & Material Sciences (AREA)
- Health & Medical Sciences (AREA)
- Organic Chemistry (AREA)
- Life Sciences & Earth Sciences (AREA)
- Virology (AREA)
- General Health & Medical Sciences (AREA)
- Molecular Biology (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Veterinary Medicine (AREA)
- Chemical Kinetics & Catalysis (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Communicable Diseases (AREA)
- Biochemistry (AREA)
- Pharmacology & Pharmacy (AREA)
- Animal Behavior & Ethology (AREA)
- Oncology (AREA)
- Public Health (AREA)
- Engineering & Computer Science (AREA)
- Biotechnology (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
- Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
- Medicines Containing Material From Animals Or Micro-Organisms (AREA)
- Saccharide Compounds (AREA)
- Preparation Of Compounds By Using Micro-Organisms (AREA)
Applications Claiming Priority (4)
Application Number | Priority Date | Filing Date | Title |
---|---|---|---|
SE8801729 | 1988-05-06 | ||
SE8801729A SE8801729D0 (sv) | 1988-05-06 | 1988-05-06 | Purine derivatives for use in therapy |
SE8900255 | 1989-01-25 | ||
PCT/SE1989/000255 WO1989010923A1 (en) | 1988-05-06 | 1989-05-05 | Derivatives of purine, process for their preparation and a pharmaceutical preparation |
Publications (3)
Publication Number | Publication Date |
---|---|
FI905475A0 true FI905475A0 (fi) | 1990-11-05 |
FI98729B FI98729B (fi) | 1997-04-30 |
FI98729C FI98729C (fi) | 1997-08-11 |
Family
ID=20372263
Family Applications (1)
Application Number | Title | Priority Date | Filing Date |
---|---|---|---|
FI905475A FI98729C (fi) | 1988-05-06 | 1990-11-05 | Menetelmä farmaseuttisesti vaikuttavan puriinijohdannaisen valmistamiseksi |
Country Status (18)
Country | Link |
---|---|
EP (1) | EP0343133B1 (fi) |
JP (1) | JP2866688B2 (fi) |
KR (1) | KR0141913B1 (fi) |
AT (1) | ATE74603T1 (fi) |
CA (1) | CA1340909C (fi) |
DE (1) | DE68901153D1 (fi) |
DK (1) | DK174986B1 (fi) |
ES (1) | ES2033548T3 (fi) |
FI (1) | FI98729C (fi) |
GR (1) | GR3004482T3 (fi) |
HU (1) | HU207082B (fi) |
IE (1) | IE62066B1 (fi) |
IL (1) | IL90166A (fi) |
MY (1) | MY108541A (fi) |
NZ (1) | NZ229002A (fi) |
PT (1) | PT90478B (fi) |
SE (1) | SE8801729D0 (fi) |
WO (1) | WO1989010923A1 (fi) |
Families Citing this family (26)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
GB8904855D0 (en) * | 1989-03-03 | 1989-04-12 | Beecham Group Plc | Pharmaceutical treatment |
US6346627B1 (en) * | 1990-02-01 | 2002-02-12 | Emory University | Intermediates in the synthesis of 1,3-oxathiolane nucleoside enantiomers |
EP0539487A1 (en) * | 1990-07-19 | 1993-05-05 | Beecham Group Plc | Antiviral phosphono-alken derivatives of purines |
GB9020932D0 (en) * | 1990-09-26 | 1990-11-07 | Wellcome Found | Heterocyclic compounds |
US5208221A (en) * | 1990-11-29 | 1993-05-04 | Bristol-Myers Squibb Company | Antiviral (phosphonomethoxy) methoxy purine/pyrimidine derivatives |
US5360714A (en) * | 1992-08-28 | 1994-11-01 | Fox Chase Cancer Center | Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof |
US5334525A (en) * | 1992-08-28 | 1994-08-02 | Fox Chase Cancer Center | Hepadnavirus polymerase gene product having RNA-dependent DNA priming and reverse transcriptase activities and methods of measuring the activities thereof |
US5798340A (en) | 1993-09-17 | 1998-08-25 | Gilead Sciences, Inc. | Nucleotide analogs |
JPH09506333A (ja) * | 1993-09-17 | 1997-06-24 | ギリアード サイエンシーズ,インコーポレイテッド | 治療化合物の投薬方法 |
US5656745A (en) * | 1993-09-17 | 1997-08-12 | Gilead Sciences, Inc. | Nucleotide analogs |
DE19540798A1 (de) * | 1995-11-02 | 1997-05-07 | Hoechst Ag | Alkylxanthinphosphonate und Alkylxanthinphosphinoxide und deren Verwendung als Arzneimittel |
US20030040467A1 (en) | 1998-06-15 | 2003-02-27 | Mary Ann Pelleymounter | Ig/ob fusions and uses thereof. |
US5717095A (en) * | 1995-12-29 | 1998-02-10 | Gilead Sciences, Inc. | Nucleotide analogs |
EP0874858A1 (en) * | 1995-12-29 | 1998-11-04 | Gilead Sciences, Inc. | Nucleotide analogs |
US6703394B2 (en) | 1996-02-16 | 2004-03-09 | Medivir Ab | Acyclic nucleoside derivatives |
US5869493A (en) * | 1996-02-16 | 1999-02-09 | Medivir Ab | Acyclic nucleoside derivatives |
JP2009298785A (ja) * | 1997-02-10 | 2009-12-24 | Medivir Ab | 非環状ヌクレオシド誘導体の合成 |
WO1998034917A2 (en) * | 1997-02-10 | 1998-08-13 | Medivir Ab | Synthesis of acyclic nucleoside derivatives |
US6184376B1 (en) | 1997-02-10 | 2001-02-06 | Mediver Ab | Synthesis of acyclic nucleoside derivatives |
US6753322B2 (en) | 2000-06-06 | 2004-06-22 | Pfizer Inc | 2-aminocarbonyl-9H-purine derivatives |
US7241890B2 (en) | 2001-10-30 | 2007-07-10 | Conforma Therapeutics Corporation | Purine analogs having HSP90-inhibiting activity |
TWI332507B (en) | 2002-11-19 | 2010-11-01 | Hoffmann La Roche | Antiviral nucleoside derivatives |
WO2005028434A2 (en) | 2003-09-18 | 2005-03-31 | Conforma Therapeutics Corporation | Novel heterocyclic compounds as hsp90-inhibitors |
MX2007011903A (es) | 2005-03-30 | 2007-12-05 | Conforma Therapeutics Corp | Alquinil pirrolopirimidinas y analogos relacionados como inhibidores de hsp90. |
US8580859B2 (en) | 2008-08-01 | 2013-11-12 | Bioxiness Pharmaceuticals, Inc. | Methionine analogs and methods of using same |
CN102250126A (zh) * | 2010-05-18 | 2011-11-23 | 北京化工大学 | 一种双嘌呤类衍生物及其合成 |
Family Cites Families (5)
Publication number | Priority date | Publication date | Assignee | Title |
---|---|---|---|---|
DK472683A (da) * | 1982-10-14 | 1984-04-15 | Wellcome Found | Fremgangsmaade til fremstilling af purinderivater |
CS233665B1 (en) * | 1983-01-06 | 1985-03-14 | Antonin Holy | Processing of isomere o-phosphonylmethylderivative of anantiomere racemic vicinal diene |
IL73682A (en) * | 1983-12-20 | 1991-08-16 | Medivir Ab | Antiviral pharmaceutical compositions containing 9-hydroxy aliphatic derivatives of guanine,some new such derivatives and process for their preparation |
SE8406538D0 (sv) * | 1984-12-21 | 1984-12-21 | Astra Laekemedel Ab | Novel derivatives of purine |
MY101126A (en) * | 1985-12-13 | 1991-07-31 | Beecham Group Plc | Novel compounds |
-
1988
- 1988-05-06 SE SE8801729A patent/SE8801729D0/xx unknown
-
1989
- 1989-05-03 IL IL9016689A patent/IL90166A/en active IP Right Grant
- 1989-05-04 NZ NZ229002A patent/NZ229002A/en unknown
- 1989-05-05 JP JP1505738A patent/JP2866688B2/ja not_active Expired - Fee Related
- 1989-05-05 AT AT89850146T patent/ATE74603T1/de not_active IP Right Cessation
- 1989-05-05 CA CA000598887A patent/CA1340909C/en not_active Expired - Fee Related
- 1989-05-05 DE DE8989850146T patent/DE68901153D1/de not_active Expired - Fee Related
- 1989-05-05 WO PCT/SE1989/000255 patent/WO1989010923A1/en active IP Right Grant
- 1989-05-05 MY MYPI89000618A patent/MY108541A/en unknown
- 1989-05-05 ES ES198989850146T patent/ES2033548T3/es not_active Expired - Lifetime
- 1989-05-05 HU HU893004A patent/HU207082B/hu not_active IP Right Cessation
- 1989-05-05 IE IE147289A patent/IE62066B1/en not_active IP Right Cessation
- 1989-05-05 EP EP89850146A patent/EP0343133B1/en not_active Expired - Lifetime
- 1989-05-15 PT PT90478A patent/PT90478B/pt not_active IP Right Cessation
-
1990
- 1990-01-06 KR KR90700035A patent/KR0141913B1/ko not_active IP Right Cessation
- 1990-11-05 FI FI905475A patent/FI98729C/fi active IP Right Grant
- 1990-11-05 DK DK199002649A patent/DK174986B1/da not_active IP Right Cessation
-
1992
- 1992-05-05 GR GR920400840T patent/GR3004482T3/el unknown
Also Published As
Publication number | Publication date |
---|---|
HU893004D0 (en) | 1991-09-30 |
WO1989010923A1 (en) | 1989-11-16 |
DE68901153D1 (de) | 1992-05-14 |
CA1340909C (en) | 2000-02-22 |
IL90166A (en) | 1996-09-12 |
IL90166A0 (en) | 1989-12-15 |
PT90478A (pt) | 1989-11-30 |
AU626300B2 (en) | 1992-07-30 |
DK174986B1 (da) | 2004-04-13 |
HU207082B (en) | 1993-03-01 |
HUT57767A (en) | 1991-12-30 |
SE8801729D0 (sv) | 1988-05-06 |
EP0343133A1 (en) | 1989-11-23 |
GR3004482T3 (fi) | 1993-03-31 |
FI98729C (fi) | 1997-08-11 |
ATE74603T1 (de) | 1992-04-15 |
NZ229002A (en) | 1997-05-26 |
DK264990A (da) | 1990-11-05 |
IE891472L (en) | 1989-11-06 |
ES2033548T3 (es) | 1993-03-16 |
MY108541A (en) | 1996-10-31 |
DK264990D0 (da) | 1990-11-05 |
KR0141913B1 (en) | 1998-06-01 |
PT90478B (pt) | 1994-08-31 |
JPH03504243A (ja) | 1991-09-19 |
EP0343133B1 (en) | 1992-04-08 |
AU3572689A (en) | 1989-11-29 |
JP2866688B2 (ja) | 1999-03-08 |
IE62066B1 (en) | 1994-12-14 |
FI98729B (fi) | 1997-04-30 |
Similar Documents
Publication | Publication Date | Title |
---|---|---|
FI98729B (fi) | Menetelmä farmaseuttisesti vaikuttavan puriinijohdannaisen valmistamiseksi | |
EE02995B1 (et) | 1,3-oksatiolaannukleosiidi analoogide kasutamine hepatiit B ravimpreparaatide valmistamiseks | |
ES2087090T3 (es) | Nucleosidos pirimidinicos. | |
CU22305A3 (es) | Procedimiento para la preparacion de un derivado de aminoacidos | |
NO166448C (no) | Analogifremgangsmaate for fremstilling av terapeutisk aktive tiazolidindioner. | |
EP0371731A3 (en) | Quinazolinone derivatives | |
ES2196004T3 (es) | Procedimiento para preparar 1,3-oxatiolanos sustituidos con propiedades antivirales. | |
FI890689A0 (fi) | 3-alkenyl-1-azabicyklo-/3.2.0/ -hept-2-en-2-karboxylsyrafoereningar. | |
HUT46536A (en) | Process for producing antianxietive pharmaceutical compositions | |
PT76903B (en) | Process for preparing novel derivatives of guanine and of pharmaceutical compositions containing the same | |
ES2169117T3 (es) | Uso de derivados de 2-aminopurina en el tratamiento y profilaxis de la infeccion por el virus 7 del herpes humano. | |
ES8308335A1 (es) | Un procedimiento para la preparacion de nuevos derivados de desoxiuridina. | |
TH8242EX (th) | อนุพันธ์ของพิวรีนและการใช้สารเหล่านั้นในการรักษา |
Legal Events
Date | Code | Title | Description |
---|---|---|---|
BB | Publication of examined application | ||
FG | Patent granted |
Owner name: MEDIVIR AB |