FI884087A7 - Menetelmä androsta-1,4-dieeni-3,17-dionin metyleenijohdannaisten val mistamiseksi - Google Patents

Menetelmä androsta-1,4-dieeni-3,17-dionin metyleenijohdannaisten val mistamiseksi Download PDF

Info

Publication number
FI884087A7
FI884087A7 FI884087A FI884087A FI884087A7 FI 884087 A7 FI884087 A7 FI 884087A7 FI 884087 A FI884087 A FI 884087A FI 884087 A FI884087 A FI 884087A FI 884087 A7 FI884087 A7 FI 884087A7
Authority
FI
Finland
Prior art keywords
androsta
dione
diene
preparation
methylene derivatives
Prior art date
Application number
FI884087A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI884087L (fi
FI884087A0 (fi
Inventor
Paolo Lombardi
Antonio Longo
Original Assignee
Erba Carlo Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Erba Carlo Spa filed Critical Erba Carlo Spa
Publication of FI884087A0 publication Critical patent/FI884087A0/fi
Publication of FI884087L publication Critical patent/FI884087L/fi
Publication of FI884087A7 publication Critical patent/FI884087A7/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0011—Androstane derivatives substituted in position 17 by a keto group
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00—Antineoplastic agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J1/00—Normal steroids containing carbon, hydrogen, halogen or oxygen, not substituted in position 17 beta by a carbon atom, e.g. estrane, androstane
    • C07J1/0003—Androstane derivatives
    • C07J1/0018—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa
    • C07J1/0022—Androstane derivatives substituted in position 17 beta, not substituted in position 17 alfa the substituent being an OH group free esterified or etherified
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07J—STEROIDS
    • C07J75/00—Processes for the preparation of steroids in general

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Steroid Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Hydrogenated Pyridines (AREA)
  • Saccharide Compounds (AREA)
FI884087A 1987-09-11 1988-09-06 Menetelmä androsta-1,4-dieeni-3,17-dionin metyleenijohdannaisten val mistamiseksi FI884087A7 (fi)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
GB878721383A GB8721383D0 (en) 1987-09-11 1987-09-11 Preparation of methylene derivatives

Publications (3)

Publication Number Publication Date
FI884087A0 FI884087A0 (fi) 1988-09-06
FI884087L FI884087L (fi) 1989-03-12
FI884087A7 true FI884087A7 (fi) 1989-03-12

Family

ID=10623618

Family Applications (1)

Application Number Title Priority Date Filing Date
FI884087A FI884087A7 (fi) 1987-09-11 1988-09-06 Menetelmä androsta-1,4-dieeni-3,17-dionin metyleenijohdannaisten val mistamiseksi

Country Status (16)

Country Link
US (1) US4876045A (enExample)
EP (1) EP0307134B1 (enExample)
JP (1) JP2791046B2 (enExample)
KR (1) KR970005315B1 (enExample)
AT (1) ATE78488T1 (enExample)
AU (1) AU602608B2 (enExample)
CA (1) CA1316914C (enExample)
DE (1) DE3872995T2 (enExample)
ES (1) ES2051858T3 (enExample)
FI (1) FI884087A7 (enExample)
GB (1) GB8721383D0 (enExample)
GR (1) GR3005296T3 (enExample)
HU (1) HU199156B (enExample)
IL (1) IL87657A (enExample)
SU (1) SU1681731A3 (enExample)
UA (1) UA6044A1 (enExample)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
GB9201224D0 (en) * 1992-01-21 1992-03-11 Erba Carlo Spa Difluoromethylenandrostenone derivatives and process for their preparation
AU5873300A (en) * 1999-07-07 2001-01-30 Pharmacia & Upjohn Company Process to prepare exemestane
CN1304413C (zh) * 2002-10-24 2007-03-14 上海华拓医药科技发展有限公司 一种抗癌药物依西美坦制备方法
ATE548375T1 (de) * 2004-01-16 2012-03-15 Cedarburg Pharmaceuticals Inc Exemestan und zwischenprodukte davon und verfahren zu dessen herstellung
US10174070B2 (en) 2005-09-30 2019-01-08 Endece Llc 6-substituted estradiol derivatives and methods of use
US20070225354A1 (en) * 2006-03-21 2007-09-27 Eric Marchewitz Use of dihydrolipoamide for enhancing physical performance
US7569719B1 (en) * 2006-10-25 2009-08-04 Loctite (R&D) Limited Method of preparing electron deficient olefins
US20080275259A1 (en) * 2007-05-04 2008-11-06 Scinopharm Taiwan, Ltd Process for preparing aromatase inhibitors
AU2008269148B2 (en) * 2007-06-25 2013-02-21 Scinopharm Taiwan, Ltd. Crystalline polymorph of 7-ethyl-10-hydroxycamptothecin
EP2170328A2 (en) * 2007-06-25 2010-04-07 ScinoPharm Taiwan, Ltd. Crystalline polymorph of exemestane
US7973119B1 (en) 2007-10-24 2011-07-05 Loctite (R&D) Limited Adhesive systems using imines and salts thereof and precursurs to electron deficient olefins
US8053589B1 (en) * 2007-10-24 2011-11-08 Henkel Ireland Limited Imines and methods of preparing electron deficient olefins using such novel imines
KR101561712B1 (ko) * 2007-10-24 2015-10-19 헨켈 아이피 앤드 홀딩 게엠베하 활성화된 메틸렌 시약 및 그로부터 제조되는 경화가능한 조성물
US8686105B2 (en) 2007-10-24 2014-04-01 Henkel IP & Holding GmbH Adhesive systems using imines and salts thereof, precursors to electron deficient olefins and coreactants therefor
EP2217559B1 (en) * 2007-10-24 2017-06-28 Henkel IP & Holding GmbH Electron deficient olefins
US8399698B1 (en) 2008-10-24 2013-03-19 Henkel Ireland Limited Substituted activated methylene reagents and methods of using such reagents to form electron deficient olefins
US10196471B1 (en) 2008-10-24 2019-02-05 Henkel IP & Holding GmbH Curable composition having an electron deficient olefin
ES2587977T3 (es) 2009-05-01 2016-10-28 Celloxess Llc Tratamiento de la infertilidad masculina secundaria al estrés oxidativo de esperma
MX343059B (es) 2010-09-14 2016-10-24 Endece Llc Derivados de desmetil-estradiol sustituido en 6 como agonistas de er-beta selectivos.
CN105085599A (zh) * 2014-05-16 2015-11-25 绍兴文理学院 一种依西美坦中间体17,17-乙二氧基-6-亚甲基雄甾-1,4-二烯-3-酮及其制备方法和应用
CN105294807A (zh) * 2014-06-26 2016-02-03 浙江医药股份有限公司新昌制药厂 一种依西美坦中间体肟化合物及其制备方法和应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3004508C2 (de) * 1980-02-05 1981-12-10 Schering Ag Berlin Und Bergkamen, 1000 Berlin Verfahren zur Herstellung von 6-Methylensteroiden
GB8517360D0 (en) * 1985-07-09 1985-08-14 Erba Farmitalia Substituted androsta-1,4-diene-3,17-diones

Also Published As

Publication number Publication date
HU199156B (en) 1990-01-29
FI884087L (fi) 1989-03-12
HUT48273A (en) 1989-05-29
ATE78488T1 (de) 1992-08-15
CA1316914C (en) 1993-04-27
JPH01104095A (ja) 1989-04-21
KR970005315B1 (ko) 1997-04-15
GR3005296T3 (enExample) 1993-05-24
JP2791046B2 (ja) 1998-08-27
FI884087A0 (fi) 1988-09-06
SU1681731A3 (ru) 1991-09-30
US4876045A (en) 1989-10-24
UA6044A1 (uk) 1994-12-29
AU602608B2 (en) 1990-10-18
ES2051858T3 (es) 1994-07-01
GB8721383D0 (en) 1987-10-21
EP0307134B1 (en) 1992-07-22
AU2198088A (en) 1989-03-16
DE3872995D1 (de) 1992-08-27
KR890005141A (ko) 1989-05-13
IL87657A (en) 1993-02-21
EP0307134A1 (en) 1989-03-15
IL87657A0 (en) 1989-02-28
DE3872995T2 (de) 1992-12-10

Similar Documents

Publication Publication Date Title
NO862753L (no) Fremgangsmaate for fremstilling av andosta-1,4-diene-3,17-dioner.
FI882461A0 (fi) 9-alfa-hydroksi-steroidit, menetelmä niiden valmistamiseksi ja menetelmä vastaavien 9(11)-dehydro-johdannaisten valmistamiseksi
UA6044A1 (uk) Спосіб одержання метіленових похідних андроста-1,4 -діен-3,17-діона
FI874189L (fi) Epimeerisen jakaantumisen säätelymenetelmä pregnaanijohdannaisten 16,17-asetaalien valmistuksessa
FI890302L (fi) Parannus androsta-1,4-dieeni-3,17-dionin 6-metyleenijohdannaisten synteesissä
FI873052A7 (fi) Menetelmä uusien 6- tai 7-metyleeniandrosta-1,4-dieeni-3,17-dionijohdannaisten valmistamiseksi.
FI872659A7 (fi) Menetelmä uusien androst-4-eeni-3,17-dionien valmistamiseksi.
NO905029L (no) Fremgangsmaate for fremstilling av steroider.
AU2761488A (en) Steroidal compounds and process for lengthening the side-chain of certain steroids
PT85122A (en) Process for the preparation of methylene derivatives of androst-4-ene-3,17-diones
BA97185B1 (bs) Postupak za dobijanje supstituisanih androsta-1,4-dien-3,17-diona
FI875322A7 (fi) Menetelmä 17a -hydroksi-D-homo-1,4 -pregnadieeni-3,20-dionin valmista miseksi.
FI873489A7 (fi) Menetelmä 4-androsteeni-3,17-dionin ja 1,4-androstadieeni-3,17-dionin valmistamiseksi.
CS240886A2 (en) Method of 1-methyl-1, 4-androstadiene-3, 17-dione production
PL263783A1 (en) Method of obtaining 6-alpha-fluoro-16-alpha,17-alpha-isopropylidenedioxy-11-betha,21-dihydroxy-4-pregnene-3,20-dione
MD21B1 (ro) Metoda de obtinere a 22(r,s) 11beta, 21-dihidroxi-16alpha, 17-butilidenbisoxipregn-1,4-dien-3,20 dionului
IE871593L (en) Androst-4-ene-3,20-dione derivatives
IE871594L (en) Androst-4-ene-3,20-dione derivatives
PL270363A1 (en) Method of obtaining derivatives of pregnane
AR243198A1 (es) Procedimiento para la elaboracion de compuesto 9alfa-21-dihalogeno-11beta- hidroxi-17alfa-alcanoiloxi-6alfa-fluor-16beta-metilp regna-1,4-dien-3,20-diona
AR243199A1 (es) Procedimiento para elaborar compuestos de 9alfa,21-dihalogeno-llbeta- hidroxi-17alfa-alcanoiloxi-6alfa-fluor-16beta-metil- pregna-1,4-dien-3,20- diona
NO902430D0 (no) Fremgangsmaate for fremstilling av 3beta- 17beta-hydroxysubstituerte steroider.
CS128788A2 (en) Method of 11-beta, 21-dihydroxy-16-alpha, 17-butylidenbis oxypregna-1,4-diene-3,20-dione production
KR900011902A (ko) 생물전환에 의한 하이드로코티손으로부터 프레드니솔론의 제조방법
PL251409A2 (en) Method of obtaining 2-methylene-4,6-androstadiene-3,17-dione

Legal Events

Date Code Title Description
FD Application lapsed

Owner name: FARMITALIA CARLO ERBA S.R.L