FI882875A - Menetelmä valmistaa farmakologisesti arvokasta substituoitua aminokarbonyylioksipropionyyli-histidyyliaminoalkoholiyhdistettä - Google Patents

Menetelmä valmistaa farmakologisesti arvokasta substituoitua aminokarbonyylioksipropionyyli-histidyyliaminoalkoholiyhdistettä Download PDF

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Publication number
FI882875A
FI882875A FI882875A FI882875A FI882875A FI 882875 A FI882875 A FI 882875A FI 882875 A FI882875 A FI 882875A FI 882875 A FI882875 A FI 882875A FI 882875 A FI882875 A FI 882875A
Authority
FI
Finland
Prior art keywords
aminocarbonyloxypropionyl
histidylamino
preparing
alcohol compound
pharmacologically valuable
Prior art date
Application number
FI882875A
Other languages
English (en)
Swedish (sv)
Other versions
FI96202C (fi
FI96202B (fi
FI882875A0 (fi
Inventor
Keiji Hemmi
Masahiro Neya
Hiroshi Marusawa
Keisuke Imai
Natsuko Kayakiri
Masashi Hashimoto
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB878714597A external-priority patent/GB8714597D0/en
Priority claimed from GB878725511A external-priority patent/GB8725511D0/en
Priority claimed from GB888805389A external-priority patent/GB8805389D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI882875A0 publication Critical patent/FI882875A0/fi
Publication of FI882875A publication Critical patent/FI882875A/fi
Application granted granted Critical
Publication of FI96202B publication Critical patent/FI96202B/fi
Publication of FI96202C publication Critical patent/FI96202C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/20—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carbonic acid, or sulfur or nitrogen analogues thereof
    • C07D295/205—Radicals derived from carbonic acid
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/86—Renin inhibitors

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Veterinary Medicine (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Cardiology (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Pyridine Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyrrole Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI882875A 1987-06-22 1988-06-16 Menetelmä valmistaa farmakologisesti arvokasta substituoitua aminokarbonyylioksipropionyyli-histidyyliaminoalkoholiyhdistettä FI96202C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB8714597 1987-06-22
GB878714597A GB8714597D0 (en) 1987-06-22 1987-06-22 Peptide compounds
GB8725511 1987-10-30
GB878725511A GB8725511D0 (en) 1987-10-30 1987-10-30 Peptide compounds
GB888805389A GB8805389D0 (en) 1988-03-07 1988-03-07 New peptide compounds process for preparation thereof & pharmaceutical composition comprising same
GB8805389 1988-03-07

Publications (4)

Publication Number Publication Date
FI882875A0 FI882875A0 (fi) 1988-06-16
FI882875A true FI882875A (fi) 1988-12-23
FI96202B FI96202B (fi) 1996-02-15
FI96202C FI96202C (fi) 1996-05-27

Family

ID=27263470

Family Applications (1)

Application Number Title Priority Date Filing Date
FI882875A FI96202C (fi) 1987-06-22 1988-06-16 Menetelmä valmistaa farmakologisesti arvokasta substituoitua aminokarbonyylioksipropionyyli-histidyyliaminoalkoholiyhdistettä

Country Status (20)

Country Link
US (2) US4921855A (fi)
EP (1) EP0300189B1 (fi)
JP (1) JPH0625147B2 (fi)
KR (1) KR950003926B1 (fi)
CN (1) CN1026892C (fi)
AR (1) AR247733A1 (fi)
AT (1) ATE113585T1 (fi)
AU (1) AU617674B2 (fi)
DE (1) DE3851986T2 (fi)
DK (1) DK340088A (fi)
ES (1) ES2067456T3 (fi)
FI (1) FI96202C (fi)
HK (1) HK18796A (fi)
HU (2) HU202212B (fi)
IE (1) IE65807B1 (fi)
IL (1) IL86782A (fi)
NO (1) NO175371C (fi)
PH (1) PH27181A (fi)
PT (1) PT87754B (fi)
RU (1) RU1801107C (fi)

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US4902706A (en) * 1988-07-01 1990-02-20 G. D. Searle & Co. Aminoalkylaminocarbonyl aminodiol amino acid derivatives as antihypertensive agents
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US5229369A (en) * 1988-07-01 1993-07-20 G. D. Searle & Co. Aminoalkylaminocarbonyl aminodiol amino acid derivatives as anti-hypertensive agents
US5229420A (en) * 1988-07-01 1993-07-20 G. D. Searle & Co. Ethereal N-terminal aminodiol amino acid derivatives as anti-hypertensive agents
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KR950702188A (ko) * 1992-07-02 1995-06-19 후지야마 로오 아미노산 유도체 생산 및 합성의 신규 중간체
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US5317039A (en) * 1992-07-20 1994-05-31 G. D. Searle & Co. Cyclopropyl-alanine aryl/alkylsulfide/sulfonyl-terminated amino-diol compounds for treatment of hypertension
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Also Published As

Publication number Publication date
HU211977A9 (en) 1996-01-29
JPS6419071A (en) 1989-01-23
KR950003926B1 (ko) 1995-04-20
DE3851986D1 (de) 1994-12-08
DK340088A (da) 1988-12-23
KR890000434A (ko) 1989-03-14
IE881778L (en) 1988-12-22
EP0300189B1 (en) 1994-11-02
PH27181A (en) 1993-04-16
FI96202C (fi) 1996-05-27
JPH0625147B2 (ja) 1994-04-06
CN1030411A (zh) 1989-01-18
NO175371C (no) 1994-10-05
HUT47917A (en) 1989-04-28
FI96202B (fi) 1996-02-15
DK340088D0 (da) 1988-06-21
IE65807B1 (en) 1995-11-15
CN1026892C (zh) 1994-12-07
HK18796A (en) 1996-02-09
DE3851986T2 (de) 1995-03-09
HU202212B (en) 1991-02-28
PT87754B (pt) 1992-10-30
AU1819088A (en) 1988-12-22
PT87754A (pt) 1988-07-01
IL86782A0 (en) 1988-11-30
EP0300189A2 (en) 1989-01-25
FI882875A0 (fi) 1988-06-16
NO882732D0 (no) 1988-06-21
ES2067456T3 (es) 1995-04-01
RU1801107C (ru) 1993-03-07
NO175371B (no) 1994-06-27
US4921855A (en) 1990-05-01
NO882732L (no) 1988-12-23
EP0300189A3 (en) 1990-08-22
ATE113585T1 (de) 1994-11-15
US5142048A (en) 1992-08-25
AR247733A1 (es) 1995-03-31
AU617674B2 (en) 1991-12-05
IL86782A (en) 1993-04-04

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