FI872827A - Anvaendning av karbocykliskt och heterocykliskt kondenserade dihydropyridiner som kardioskyddande medel och nya heterocykliskt och karbocykliskt kondenserade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter. - Google Patents

Anvaendning av karbocykliskt och heterocykliskt kondenserade dihydropyridiner som kardioskyddande medel och nya heterocykliskt och karbocykliskt kondenserade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter. Download PDF

Info

Publication number
FI872827A
FI872827A FI872827A FI872827A FI872827A FI 872827 A FI872827 A FI 872827A FI 872827 A FI872827 A FI 872827A FI 872827 A FI872827 A FI 872827A FI 872827 A FI872827 A FI 872827A
Authority
FI
Finland
Prior art keywords
och
kondenserade
karbocykliskt
heterocykliskt
dihydropyridiner
Prior art date
Application number
FI872827A
Other languages
English (en)
Finnish (fi)
Other versions
FI872827A0 (fi
Inventor
Walter Loesel
Gerd Schnorrenberg
Otto Roos
Dietrich Arndts
Ilse Streller
Werner Traunecker
Original Assignee
Boehringer Ingelheim Kg
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Boehringer Ingelheim Kg filed Critical Boehringer Ingelheim Kg
Publication of FI872827A0 publication Critical patent/FI872827A0/fi
Publication of FI872827A publication Critical patent/FI872827A/fi
Priority to FI903632A priority Critical patent/FI903632A0/fi
Priority to FI923048A priority patent/FI923048A0/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D401/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom
    • C07D401/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings
    • C07D401/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, at least one ring being a six-membered ring with only one nitrogen atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P3/00—Drugs for disorders of the metabolism
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P39/00—General protective or antinoxious agents
    • A61P39/02—Antidotes
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/12—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with radicals, substituted by hetero atoms, attached to carbon atoms of the nitrogen-containing ring
    • C07D217/18—Aralkyl radicals
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D405/00—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom
    • C07D405/02—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings
    • C07D405/12—Heterocyclic compounds containing both one or more hetero rings having oxygen atoms as the only ring hetero atoms, and one or more rings having nitrogen as the only ring hetero atom containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings
    • C07D407/12—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Toxicology (AREA)
  • Diabetes (AREA)
  • Hematology (AREA)
  • Obesity (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Hydrogenated Pyridines (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Indole Compounds (AREA)
  • Heterocyclic Compounds Containing Sulfur Atoms (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Nitrogen And Oxygen As The Only Ring Hetero Atoms (AREA)
FI872827A 1986-06-26 1987-06-26 Anvaendning av karbocykliskt och heterocykliskt kondenserade dihydropyridiner som kardioskyddande medel och nya heterocykliskt och karbocykliskt kondenserade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter. FI872827A (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI903632A FI903632A0 (fi) 1986-06-26 1990-07-18 Karbocykliska och heterocykliska fusionerade dihydropyridiner som kardioskyddande medel och nya heterocykliska och karbocykliska fusionerade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter foer deras framstaellning.
FI923048A FI923048A0 (fi) 1986-06-26 1992-07-01 Karbocykliska och heterocykliska fusionerade dihydropyridiner som kardioskyddande medel och nya heterocykliska och karbocykliska fusionerade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter foer deras framstaellning.

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE19863621413 DE3621413A1 (de) 1986-06-26 1986-06-26 Verwendung carbocyclisch und heterocyclisch annelierter dihydropyridine als cardioprotektive mittel sowie neue heterocyclisch und carbocyclisch anellierte dihydropyridine, verfahren zu deren herstellung und zwischenstufen fuer deren herstellung

Publications (2)

Publication Number Publication Date
FI872827A0 FI872827A0 (fi) 1987-06-26
FI872827A true FI872827A (fi) 1987-12-27

Family

ID=6303756

Family Applications (1)

Application Number Title Priority Date Filing Date
FI872827A FI872827A (fi) 1986-06-26 1987-06-26 Anvaendning av karbocykliskt och heterocykliskt kondenserade dihydropyridiner som kardioskyddande medel och nya heterocykliskt och karbocykliskt kondenserade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter.

Country Status (18)

Country Link
EP (1) EP0251194B1 (ko)
JP (1) JPS63258458A (ko)
KR (2) KR890000480A (ko)
AU (1) AU598558B2 (ko)
DD (1) DD264429A5 (ko)
DE (2) DE3621413A1 (ko)
DK (1) DK323887A (ko)
ES (1) ES2053471T3 (ko)
FI (1) FI872827A (ko)
GR (1) GR3007545T3 (ko)
HU (1) HU203752B (ko)
IE (1) IE59546B1 (ko)
IL (1) IL82995A0 (ko)
NO (1) NO872672L (ko)
PL (1) PL159840B1 (ko)
PT (1) PT85169B (ko)
YU (1) YU46216B (ko)
ZA (1) ZA874587B (ko)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2623810B2 (fr) * 1987-02-17 1992-01-24 Sanofi Sa Sels de l'alpha-(tetrahydro-4,5,6,7 thieno(3,2-c) pyridyl-5) (chloro-2 phenyl) -acetate de methyle dextrogyre et compositions pharmaceutiques en contenant
IL86131A0 (en) * 1987-04-24 1988-11-15 Boehringer Ingelheim Kg Benzo-and thieno-3,4-dihydropyridine derivatives,their preparation and pharmaceutical compositions containing them
DE3827727A1 (de) * 1988-08-16 1990-02-22 Boehringer Ingelheim Kg Anellierte tetrahydropyridinessigsaeurederivate, verfahren zu deren herstellung und verwendung solcher verbindungen zur kardioprotektion
GB8921304D0 (en) * 1989-09-20 1989-11-08 Wyeth John & Brother Ltd New method of treatment and heterocyclic compounds used therein
DE9017900U1 (de) 1990-12-22 1993-01-28 Boehringer Ingelheim Kg, 55218 Ingelheim 3,4-Dihydro-1-benzyl-6,7-dimethoxy-α- [di-2-(2,3,4-trimethoxyphenyl)ethyl] aminocarbonyl-isochinolin
CN1056832C (zh) * 1992-06-22 2000-09-27 贝林格尔·英格海姆公司 稠合二氢吡啶衍生物及其制法和含有其的药物组合物
CA2138788A1 (en) * 1992-06-22 1994-01-06 Dietrich Arndts Ring-closed dihydropyridines and their use in the preparation of pharmaceutical compositions
DE4343683A1 (de) * 1993-12-21 1995-06-22 Boehringer Ingelheim Kg Anellierte Dihydropyridine und deren Verwendung für die Herstellung von pharmazeutischen Zubereitungen
FR2724384B1 (fr) * 1994-09-14 1999-04-16 Cemaf Nouveaux derives de la 3,4-dihydro beta-carboline agonistes de la melatonine, leur procede de preparation et leur utilisation a titre de medicament

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2417512A1 (fr) * 1978-02-17 1979-09-14 Parcor Thieno (3,2-c) et thieno (2,3-c) pyridines, leur procede de preparation et leur application en therapeutique
DE3013906A1 (de) * 1980-04-11 1981-10-15 C.H. Boehringer Sohn, 6507 Ingelheim Substituierte (alpha) -aminocarbonyl-l-benzyl-3,4-dihydro-isochinoline, verfahren zu deren herstellung und deren verwendung
DE3309596A1 (de) * 1982-08-05 1984-04-05 Basf Ag, 6700 Ludwigshafen 2-substituierte 1-(3'-aminoalkyl)-1,2,3,4-tetrahydro-ss-carboline, ihre herstellung und verwendung als arzneimittel

Also Published As

Publication number Publication date
IL82995A0 (en) 1987-12-20
PT85169A (de) 1987-07-01
DK323887A (da) 1987-12-27
EP0251194B1 (de) 1993-03-31
GR3007545T3 (ko) 1993-08-31
DD264429A5 (de) 1989-02-01
ES2053471T3 (es) 1994-08-01
IE871689L (en) 1987-12-26
EP0251194A1 (de) 1988-01-07
PL159840B1 (pl) 1993-01-29
ZA874587B (en) 1989-02-22
DK323887D0 (da) 1987-06-25
PL266416A1 (en) 1988-09-01
HUT47932A (en) 1989-04-28
NO872672L (no) 1987-12-28
AU7477587A (en) 1988-01-07
PT85169B (pt) 1990-03-30
YU46216B (sh) 1993-05-28
KR930006639B1 (ko) 1993-07-22
KR890002144A (ko) 1989-04-08
JPS63258458A (ja) 1988-10-25
AU598558B2 (en) 1990-06-28
IE59546B1 (en) 1994-03-09
HU203752B (en) 1991-09-30
FI872827A0 (fi) 1987-06-26
DE3621413A1 (de) 1988-01-07
KR890000480A (ko) 1989-03-14
DE3785093D1 (de) 1993-05-06
NO872672D0 (no) 1987-06-25
YU119887A (en) 1988-10-31

Similar Documents

Publication Publication Date Title
FI862256A0 (fi) Grundmjukgoerare som innehaoller katjoniskt ytaktivt medel och organisk syra.
FI872299A0 (fi) Heterocykliska analoger av mevalonolaktoner och deras derivat, foerfaranden foer deras framstaellning och deras anvaendning som farmaceutiska medel.
FI874323A0 (fi) Nya imidazo-benzoxazinoner, deras framstaellning och dessa foereningar innehaollande laekemedel.
FI872841A0 (fi) Nya kromoforfoereningar, solskyddskompositioner och foerfarande foer hindrande av solbraenna.
FI870274A0 (fi) Nya alkan- och alkoxialkanderivat, foerfarande foer deras framstaellning och dessa foereningar innehaollande bekaempningsmedel foer insekter och kvalster.
FI875719A0 (fi) Nya alkansulfonanilidderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandningar.
FI900588A0 (fi) Foerfarande foer framstaellning av saerskilt som immunomodulator, antiviralt medel och/eller antiflammatoriskt medel anvaenda aemnen.
FI872827A (fi) Anvaendning av karbocykliskt och heterocykliskt kondenserade dihydropyridiner som kardioskyddande medel och nya heterocykliskt och karbocykliskt kondenserade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter.
FI894491A (fi) Nya substituerade tienopyraner, vilka aer anvaendbara som antihypertensiva medel.
FI873501A (fi) Heteroaryletylaminer, foerfarande foer framstaellning av dem och deras anvaendning som produktionsbefraemjande medel foer djur.
FI892207A (fi) 2-adamantyl-4-isotiazolin-3-oner, deras tillverkningsfoerfarande och anvaendning som baktericida och fungicida medel.
FI875723A0 (fi) Nya komplexer av vismut- eller antimonhalogenider med aminer, vilka aer laempliga som brandhindrande medel foer polymerer, och polymerkompositioner innehaollande dessa.
FI892897A (fi) Nya kondenserade diazepinoner, foerfarande foer deras framstaellning och laekemedel som innehaoller dessa foereningar.
FI871812A (fi) Nya benzotiazinonderivat, deras framstaellningsfoerfarande dessa innehaollande laekemedel och deras anvaendning.
FI875212A0 (fi) Nya aryloxi-3-amino-2-propanoler, deras framstaellning och anvaendning.
FI862136A0 (fi) Nya derivat av bicykliska aminosyror, foerfarande foer deras framstaellning, dessa innehaollande medel och deras anvaendning.
FI892896A0 (fi) Nya kondenserade diazepinoner, foerfarande foer deras framstaellning och laekemedel som innehaoller dessa foereningar.
FI883735A (fi) Framstaellning av antigener av maenniskans immunbristsjukdom, typ 1, och deras anvaendning som diagnostiska och terapeutiska medel.
FI895899A0 (fi) Nya trombolytiska proteiner, foerfarande foer deras framstaellning och dessa som aktivaemne innehaollande laekemedel.
FI874172A (fi) Nya aryloxi-aminoalkaner, deras framstaellning och anvaendning.
FI884578A0 (fi) Nya antracyklinderivat, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI912314A0 (fi) Utfaellningsmedel och flockuleringsmedel foer behandling av avfallsvatten och foerfarande, som anvaender dessa medel.
FI923048A (fi) Karbocykliska och heterocykliska fusionerade dihydropyridiner som kardioskyddande medel och nya heterocykliska och karbocykliska fusionerade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter foer deras framstaellning.
FI903632A0 (fi) Karbocykliska och heterocykliska fusionerade dihydropyridiner som kardioskyddande medel och nya heterocykliska och karbocykliska fusionerade dihydropyridiner, foerfarande foer deras framstaellning och mellanprodukter foer deras framstaellning.
FI870596A (fi) Nya antibiotika av streptogramintyp, mikrobiologiskt foerfarande foer deras framstaellning samt deras anvaendning som laekemedel och fodertillsatsmedel.

Legal Events

Date Code Title Description
FD Application lapsed
FD Application lapsed

Owner name: BOEHRINGER INGELHEIM KG