FI892897A - Nya kondenserade diazepinoner, foerfarande foer deras framstaellning och laekemedel som innehaoller dessa foereningar. - Google Patents

Nya kondenserade diazepinoner, foerfarande foer deras framstaellning och laekemedel som innehaoller dessa foereningar. Download PDF

Info

Publication number
FI892897A
FI892897A FI892897A FI892897A FI892897A FI 892897 A FI892897 A FI 892897A FI 892897 A FI892897 A FI 892897A FI 892897 A FI892897 A FI 892897A FI 892897 A FI892897 A FI 892897A
Authority
FI
Finland
Prior art keywords
kondenserade
diazepinoner
ceekemedel
nya
foerfarande foer
Prior art date
Application number
FI892897A
Other languages
English (en)
Other versions
FI892897A0 (fi
Inventor
Gerhard Mihm
Wolfgang Eberlein
Wolfhard Engel
Guenter Trummlitz
Norbert Mayer
Jonge Adriaan De
Henri Doods
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of FI892897A0 publication Critical patent/FI892897A0/fi
Publication of FI892897A publication Critical patent/FI892897A/fi
Priority to FI925819A priority Critical patent/FI925819A/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Veterinary Medicine (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Hospice & Palliative Care (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI892897A 1988-06-15 1989-06-14 Nya kondenserade diazepinoner, foerfarande foer deras framstaellning och laekemedel som innehaoller dessa foereningar. FI892897A (fi)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FI925819A FI925819A (fi) 1988-06-15 1992-12-22 Foerfarande foer framstaellning av terapeutiskt aktiva 11h-dibentso/b,e//1,4/diazepin-11-oner

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3820346A DE3820346A1 (de) 1988-06-15 1988-06-15 Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (2)

Publication Number Publication Date
FI892897A0 FI892897A0 (fi) 1989-06-14
FI892897A true FI892897A (fi) 1989-12-16

Family

ID=6356594

Family Applications (1)

Application Number Title Priority Date Filing Date
FI892897A FI892897A (fi) 1988-06-15 1989-06-14 Nya kondenserade diazepinoner, foerfarande foer deras framstaellning och laekemedel som innehaoller dessa foereningar.

Country Status (16)

Country Link
US (1) US5002943A (fi)
EP (1) EP0346745A1 (fi)
JP (1) JPH0240381A (fi)
KR (1) KR900000365A (fi)
AU (1) AU612493B2 (fi)
DD (1) DD284016A5 (fi)
DE (1) DE3820346A1 (fi)
DK (1) DK291189A (fi)
FI (1) FI892897A (fi)
HU (1) HU201759B (fi)
IL (1) IL90590A0 (fi)
NO (1) NO168477C (fi)
PH (1) PH27213A (fi)
PT (1) PT90842A (fi)
SU (1) SU1678209A3 (fi)
ZA (1) ZA894461B (fi)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3818299A1 (de) * 1988-05-30 1989-12-07 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
ATE103918T1 (de) * 1989-06-28 1994-04-15 Boehringer Ingelheim Pharma 5,11-dihydro-6h-dipyrido(3,2-b:2',3'e>(1,4>diazepin-6-one und -thione und ihre verwendung bei der aids-vorbeugung oder behandlung.
US5179090A (en) * 1989-09-11 1993-01-12 Klaus Rudolf Condensed diazepinones and medicaments containing these compounds
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
AU3754495A (en) * 1994-10-31 1996-05-23 Yamanouchi Pharmaceutical Co., Ltd. Novel benzodiazepinone derivative and medicinal composition thereof
IL131685A (en) * 1999-09-01 2007-03-08 Mordechai Erez Antiarrhythmic, antifbirillatory, and defibrillatory pharmaceutical compositions containing dibenzoazepines and dibenzodiazepines and same such novel compounds
RU2543320C2 (ru) * 2013-04-01 2015-02-27 Федеральное государственное бюджетное учреждение науки Институт физиологии Коми научного центра Уральского отделения Российской академии наук Применение 2-морфолино-5-фенил-6н-1,3,4-тиадизин, гидробромида в качестве средства, изменяющего суммарную мощность спектра вариабельности сердечного ритма и обладающего антибрадикардическими свойствами

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210648A (en) * 1977-05-31 1980-07-01 Boehringer Ingelheim Gmbh II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
EP0024582A1 (de) * 1979-08-10 1981-03-11 Byk Gulden Lomberg Chemische Fabrik GmbH Benzodiazepinone, Verfahren zu ihrer Herstellung sowie sie enthaltende Arzneimittel
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
DE3262922D1 (en) * 1981-02-02 1985-05-15 Byk Gulden Lomberg Chem Fab Tricyclic pyrrols, process for their preparation, their use and compositions containing them
EP0213293B1 (de) * 1985-06-27 1992-01-02 Dr. Karl Thomae GmbH In 11-Stellung substituierte 5,11-Dihydro-6H-pyrido-[2,3-b][1,4]benzodiazepin-6-one, Verfahren zur ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT8721978A0 (it) * 1987-09-21 1987-09-21 Angeli Inst Spa Nuovi derivati ammidinici triciclici.
US4931436A (en) * 1988-08-09 1990-06-05 Dr. Karl Thomae Gmbh Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds

Also Published As

Publication number Publication date
EP0346745A1 (de) 1989-12-20
HUT50472A (en) 1990-02-28
PT90842A (pt) 1989-12-29
DK291189D0 (da) 1989-06-14
NO168477C (no) 1992-02-26
AU612493B2 (en) 1991-07-11
SU1678209A3 (ru) 1991-09-15
AU3644689A (en) 1989-12-21
PH27213A (en) 1993-05-04
ZA894461B (en) 1991-02-27
US5002943A (en) 1991-03-26
HU201759B (en) 1990-12-28
DE3820346A1 (de) 1989-12-21
NO892432D0 (no) 1989-06-13
DD284016A5 (de) 1990-10-31
IL90590A0 (en) 1990-01-18
FI892897A0 (fi) 1989-06-14
NO168477B (no) 1991-11-18
JPH0240381A (ja) 1990-02-09
KR900000365A (ko) 1990-01-30
DK291189A (da) 1989-12-16
NO892432L (no) 1989-12-18

Similar Documents

Publication Publication Date Title
FI902734A0 (fi) Nya 2-hydroxi-n-propylaminer, dessa foereningar innehaollande laekemedel och foerfarande foer deras framstaellning.
FI873002A (fi) Substituerade hydrazoner, foerfaranden foer deras framstaellning och deras anvaendning som bekaempningsmedel foer skadedjur.
FI871452A (fi) Faergloesa ketiminer, deras framstaellning och anvaendning som foernaetningsmedel.
FI891222A (fi) Arylpiperazinylalkoxiderivat av cykliska imider, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI903739A0 (fi) Nya 5-substituerade-1,3,4-tiadiazoler, foerfarande foer deras framstaellning och deras anvaendning som bekaempningsmedel mot skadeinsekter.
FI904533A0 (fi) Nya tiazolderivat, foerfarande foer deras framstaellning och dessa innehaollande farmaceutiska blandingar.
FI891411A0 (fi) Neopentylesterderivat, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI893142A (fi) Nya aromoljor av minttyp, foerfarande foer framstaellning av desamma, och kompositioner innehaollande desamma.
FI884338A0 (fi) Nya 2-guanidino-tiazolfoereningar, deras framstaellning och anvaendning som mellanprodukter vid en famotidinprocess.
FI890285A0 (fi) Nya aminosyraglycerider, foerfaranden foer deras framstaellning, dessa innehaollande laekemedel och deras anvaendning.
FI915435A0 (fi) Nya leukotrien-b4-derivater, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI875055A0 (fi) Optiskt aktiva gyras-inhibitorer, deras framstaellning och deras anvaendning som antibiotika.
FI882443A (fi) Substituerade vinylkefalosporiner, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI890098A0 (fi) Pyrazol- och indazolpyridinaminer, foerfarande foer deras framstaellning och deras anvaendning som laekemedel.
FI892897A (fi) Nya kondenserade diazepinoner, foerfarande foer deras framstaellning och laekemedel som innehaoller dessa foereningar.
FI872774A (fi) Bensimidazoler, deras framstaellning, formulering och anvaendning som inhibitorer foer magsyraavsoendring.
FI881873A0 (fi) Kondenserade heteroalkylenkinolinaminer, foerfarande och mellanprodukter foer deras framstaellning och deras anvaendning som laekemedel.
FI890380A0 (fi) Nya kondenserande diazepinoner, foerfarande foer deras framstaellning och dessa foereningar innehaollande laekemedel.
FI891409A0 (fi) Dietylenglykolmonoestrar, foerfaranden foer deras framstaellning och deras framstaellning och deras anvaendning som laekemedel.
FI892896A0 (fi) Nya kondenserade diazepinoner, foerfarande foer deras framstaellning och laekemedel som innehaoller dessa foereningar.
FI900661A0 (fi) Nya formbara sammansaettningar som haerdas i vaerme.
FI902177A0 (fi) Kompositioner som innehaoller elastomerer och icke-karboniserade, metaller innehaollande komplex.
FI895899A0 (fi) Nya trombolytiska proteiner, foerfarande foer deras framstaellning och dessa som aktivaemne innehaollande laekemedel.
FI895226A0 (fi) Benzotiazoler, foerfarande foer deras framstaellning och deras anvaendning som bekaempningsmedel mot skadeinsekter.
FI874514A0 (fi) Halogensyklopropyl-foereningar, deras framstaellning och anvaendning som herbicida aemnen.

Legal Events

Date Code Title Description
FD Application lapsed
MM Patent lapsed

Owner name: DR. KARL THOMAE GESELLSCHAFT MIT