ZA894461B - New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds - Google Patents

New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds

Info

Publication number
ZA894461B
ZA894461B ZA894461A ZA894461A ZA894461B ZA 894461 B ZA894461 B ZA 894461B ZA 894461 A ZA894461 A ZA 894461A ZA 894461 A ZA894461 A ZA 894461A ZA 894461 B ZA894461 B ZA 894461B
Authority
ZA
South Africa
Prior art keywords
preparing
compounds
processes
pharmaceutical compositions
compositions containing
Prior art date
Application number
ZA894461A
Other languages
English (en)
Inventor
Guenter Dr Trummlitz
Trummlitz Dr Guenter
Wolfgang Eberlein
Eberlein Wolfgang
Wolfhard Engel
Engel Wolfhard
Gerhard Mihm
Mihm Gerhard
Norbert Mayer
Mayer Norbert
Adriaan De Jonge
De Jonge Adriaan
Henri Doods
Doods Henri
Original Assignee
Thomae Gmbh Dr K
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Thomae Gmbh Dr K filed Critical Thomae Gmbh Dr K
Publication of ZA894461B publication Critical patent/ZA894461B/xx

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D403/00—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00
    • C07D403/02—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings
    • C07D403/12—Heterocyclic compounds containing two or more hetero rings, having nitrogen atoms as the only ring hetero atoms, not provided for by group C07D401/00 containing two hetero rings linked by a chain containing hetero atoms as chain links
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P1/00—Drugs for disorders of the alimentary tract or the digestive system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P13/00—Drugs for disorders of the urinary system
    • A61P13/02—Drugs for disorders of the urinary system of urine or of the urinary tract, e.g. urine acidifiers
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P15/00—Drugs for genital or sexual disorders; Contraceptives
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains three hetero rings
    • C07D471/14—Ortho-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/04—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Public Health (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Endocrinology (AREA)
  • Reproductive Health (AREA)
  • Hospice & Palliative Care (AREA)
  • Urology & Nephrology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Plural Heterocyclic Compounds (AREA)
ZA894461A 1988-06-15 1989-06-13 New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds ZA894461B (en)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
DE3820346A DE3820346A1 (de) 1988-06-15 1988-06-15 Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel

Publications (1)

Publication Number Publication Date
ZA894461B true ZA894461B (en) 1991-02-27

Family

ID=6356594

Family Applications (1)

Application Number Title Priority Date Filing Date
ZA894461A ZA894461B (en) 1988-06-15 1989-06-13 New condensed diazepinones,processes for preparing them and pharmaceutical compositions containing these compounds

Country Status (16)

Country Link
US (1) US5002943A (xx)
EP (1) EP0346745A1 (xx)
JP (1) JPH0240381A (xx)
KR (1) KR900000365A (xx)
AU (1) AU612493B2 (xx)
DD (1) DD284016A5 (xx)
DE (1) DE3820346A1 (xx)
DK (1) DK291189A (xx)
FI (1) FI892897A (xx)
HU (1) HU201759B (xx)
IL (1) IL90590A0 (xx)
NO (1) NO168477C (xx)
PH (1) PH27213A (xx)
PT (1) PT90842A (xx)
SU (1) SU1678209A3 (xx)
ZA (1) ZA894461B (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3818299A1 (de) * 1988-05-30 1989-12-07 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DK0410148T3 (da) * 1989-06-28 1994-08-08 Boehringer Ingelheim Pharma Hidtil ukendte 5,11-dihydro-6H-dipyrido(3,2-b:2,3-e)-(1,4)diazepin-6-oner og -thioner og deres anvendelse til forebyggelse eller behandling af AIDS
US5179090A (en) * 1989-09-11 1993-01-12 Klaus Rudolf Condensed diazepinones and medicaments containing these compounds
US5418229A (en) * 1990-01-06 1995-05-23 Alker; David Muscarinic receptor antagonists
WO1996013488A1 (fr) * 1994-10-31 1996-05-09 Yamanouchi Pharmaceutical Co., Ltd. Nouveau derive de benzodiazepinone et composition medicinale constituee de celui-ci
IL131685A (en) 1999-09-01 2007-03-08 Mordechai Erez Antiarrhythmic, antifbirillatory, and defibrillatory pharmaceutical compositions containing dibenzoazepines and dibenzodiazepines and same such novel compounds
RU2543320C2 (ru) * 2013-04-01 2015-02-27 Федеральное государственное бюджетное учреждение науки Институт физиологии Коми научного центра Уральского отделения Российской академии наук Применение 2-морфолино-5-фенил-6н-1,3,4-тиадизин, гидробромида в качестве средства, изменяющего суммарную мощность спектра вариабельности сердечного ритма и обладающего антибрадикардическими свойствами

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4210648A (en) * 1977-05-31 1980-07-01 Boehringer Ingelheim Gmbh II-Aminoacyl-5,11-dihydro-6H-pyrido(2,3-B) (1,4)benzodiazepin-6-ones and salts thereof
US4311700A (en) * 1979-08-10 1982-01-19 Byk Gulden Lomberg Chemische Fabrik Gmbh Pyrimidobenzodiazepinones, their use and medicaments containing them
IL62792A (en) * 1980-05-07 1985-02-28 Byk Gulden Lomberg Chem Fab Acylated dihydrothienodiazepinone compounds,process for their preparation,and medicaments containing them
EP0057428B1 (de) * 1981-02-02 1985-04-10 Byk Gulden Lomberg Chemische Fabrik GmbH Tricyclische Pyrrole, Verfahren zu ihrer Herstellung, ihre Anwendung sowie sie enthaltende Arzneimittel
ATE71097T1 (de) * 1985-06-27 1992-01-15 Thomae Gmbh Dr K In 11-stellung substituierte 5,11-dihydro-6hpyrido-(2,3-b>(1,4>benzodiazepin-6-one, verfahren zur ihrer herstellung und diese verbindungen enthaltende arzneimittel.
DE3626095A1 (de) * 1986-07-31 1988-02-11 Thomae Gmbh Dr K Neue substituierte pyrido(2,3-b)(1,4)benzodiazepin-6-one, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
DE3643666A1 (de) * 1986-12-20 1988-06-30 Thomae Gmbh Dr K Neue kondensierte diazepinone, verfahren zu ihrer herstellung und diese verbindungen enthaltende arzneimittel
IT8721978A0 (it) * 1987-09-21 1987-09-21 Angeli Inst Spa Nuovi derivati ammidinici triciclici.
US4931436A (en) * 1988-08-09 1990-06-05 Dr. Karl Thomae Gmbh Condensed diazepinones, processes for preparing them and pharmaceutical compositions containing these compounds

Also Published As

Publication number Publication date
US5002943A (en) 1991-03-26
NO892432L (no) 1989-12-18
EP0346745A1 (de) 1989-12-20
HU201759B (en) 1990-12-28
PT90842A (pt) 1989-12-29
DD284016A5 (de) 1990-10-31
AU3644689A (en) 1989-12-21
NO168477C (no) 1992-02-26
NO892432D0 (no) 1989-06-13
KR900000365A (ko) 1990-01-30
FI892897A (fi) 1989-12-16
IL90590A0 (en) 1990-01-18
AU612493B2 (en) 1991-07-11
JPH0240381A (ja) 1990-02-09
HUT50472A (en) 1990-02-28
FI892897A0 (fi) 1989-06-14
DK291189D0 (da) 1989-06-14
DK291189A (da) 1989-12-16
PH27213A (en) 1993-05-04
SU1678209A3 (ru) 1991-09-15
NO168477B (no) 1991-11-18
DE3820346A1 (de) 1989-12-21

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