FI864559A0 - Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat. - Google Patents

Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat.

Info

Publication number
FI864559A0
FI864559A0 FI864559A FI864559A FI864559A0 FI 864559 A0 FI864559 A0 FI 864559A0 FI 864559 A FI864559 A FI 864559A FI 864559 A FI864559 A FI 864559A FI 864559 A0 FI864559 A0 FI 864559A0
Authority
FI
Finland
Prior art keywords
insulinderivat
derivat
nya
pct
innehaollande dessa
Prior art date
Application number
FI864559A
Other languages
English (en)
Finnish (fi)
Other versions
FI864559A (fi
Inventor
Per Balschmidt
Finn Benned Hansen
Original Assignee
Nordisk Gentofte
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Nordisk Gentofte filed Critical Nordisk Gentofte
Publication of FI864559A publication Critical patent/FI864559A/fi
Publication of FI864559A0 publication Critical patent/FI864559A0/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K14/00Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof
    • C07K14/435Peptides having more than 20 amino acids; Gastrins; Somatostatins; Melanotropins; Derivatives thereof from animals; from humans
    • C07K14/575Hormones
    • C07K14/62Insulins
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Health & Medical Sciences (AREA)
  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • Genetics & Genomics (AREA)
  • Gastroenterology & Hepatology (AREA)
  • Toxicology (AREA)
  • Endocrinology (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Diabetes (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
FI864559A 1985-03-15 1986-11-10 Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat. FI864559A0 (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DK119785A DK119785D0 (da) 1985-03-15 1985-03-15 Insulinpraeparat
PCT/DK1986/000022 WO1986005496A1 (en) 1985-03-15 1986-03-14 Novel insulin derivatives and pharmaceutical preparations containing these derivatives

Publications (2)

Publication Number Publication Date
FI864559A FI864559A (fi) 1986-11-10
FI864559A0 true FI864559A0 (fi) 1986-11-10

Family

ID=8102063

Family Applications (2)

Application Number Title Priority Date Filing Date
FI864559A FI864559A0 (fi) 1985-03-15 1986-11-10 Nya insulinderivat och farmaceutiska preparat innehaollande dessa derivat.
FI864560A FI93460C (fi) 1985-03-15 1986-11-10 Menetelmä uusien insuliinijohdannaisten valmistamiseksi

Family Applications After (1)

Application Number Title Priority Date Filing Date
FI864560A FI93460C (fi) 1985-03-15 1986-11-10 Menetelmä uusien insuliinijohdannaisten valmistamiseksi

Country Status (11)

Country Link
US (1) US5028586A (de)
EP (2) EP0216832B1 (de)
JP (2) JPS62502538A (de)
AT (2) ATE84546T1 (de)
AU (2) AU596968B2 (de)
DE (2) DE3673737D1 (de)
DK (3) DK119785D0 (de)
FI (2) FI864559A0 (de)
IL (2) IL78161A0 (de)
NO (2) NO174278C (de)
WO (2) WO1986005496A1 (de)

Families Citing this family (29)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK347086D0 (da) * 1986-07-21 1986-07-21 Novo Industri As Novel peptides
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider
US5157021A (en) * 1985-03-15 1992-10-20 Novo Nordisk A/S Insulin derivatives and pharmaceutical preparations containing these derivatives
DK437786D0 (da) * 1986-09-12 1986-09-12 Nordisk Gentofte Insulinprecursorer
AU612141B2 (en) * 1987-02-25 1991-07-04 Novo Nordisk A/S Novel insulin derivatives
BR8803345A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina humana purificada
BR8803346A (pt) * 1988-06-30 1990-02-13 Biobras Bioquimica Do Brasil S Processo aperfeicoado para producao em larga escala de cristais de insulina purificada
US5149777A (en) * 1988-07-20 1992-09-22 Novo Nordisk A/S Human insulin analogs and preparations containing them
US5716927A (en) * 1988-12-23 1998-02-10 Novo Nordisk A/S Insulin analogs having a modified B-chain
DK134189D0 (da) * 1989-03-20 1989-03-20 Nordisk Gentofte Insulinforbindelser
WO1992010284A2 (en) 1990-12-07 1992-06-25 Cnc Development, Inc. Catalytic chemical reactor
DK33591D0 (de) * 1991-02-27 1991-02-27 Novo Nordisk As
WO1992020367A1 (en) * 1991-05-24 1992-11-26 Amylin Pharmaceuticals, Inc. Treatment of anorexia and related states
US5461031A (en) * 1994-06-16 1995-10-24 Eli Lilly And Company Monomeric insulin analog formulations
AUPO269996A0 (en) * 1996-10-01 1996-10-24 Walter And Eliza Hall Institute Of Medical Research, The A method of prophylaxis and treatment
US5898067A (en) * 1997-02-07 1999-04-27 Novo Nordisk A/S Crystallization of proteins
KR20050075373A (ko) * 2002-11-01 2005-07-20 앤태어스 파머, 인코퍼레이티드 분사식 주사에 의한 인슐린 투여
DK2842576T3 (en) 2004-01-21 2017-10-16 Novo Nordisk Healthcare Ag Transglutaminase-mediated peptide conjugation
US7833513B2 (en) 2004-12-03 2010-11-16 Rhode Island Hospital Treatment of Alzheimer's Disease
EP1991575A1 (de) * 2006-02-21 2008-11-19 Novo Nordisk A/S Einkettige insulinanaloga und pharmazeutische formulierungen daraus
AU2009210570B2 (en) * 2008-01-30 2014-11-20 Indiana University Research And Technology Corporation Ester-based insulin prodrugs
TWI489992B (zh) 2008-12-19 2015-07-01 印地安那大學研究及技術公司 醯胺系胰高血糖素超級家族之胜肽前驅藥物
PE20120331A1 (es) * 2008-12-19 2012-04-14 Univ Indiana Res & Tech Corp Agentes medicinales unidos a dipeptido
CN103119057B (zh) 2010-06-24 2016-06-15 印第安纳大学研究及科技有限公司 基于酰胺的胰岛素前药
WO2013096386A1 (en) 2011-12-20 2013-06-27 Indiana University Research And Technology Corporation Ctp-based insulin analogs for treatment of diabetes
CN108383902A (zh) 2012-09-26 2018-08-10 印第安纳大学研究及科技有限公司 胰岛素类似物二聚体
US20160024169A1 (en) 2013-03-14 2016-01-28 Indiana University Research And Technology Corporation Insulin-incretin conjugates
ES2947409T3 (es) 2014-09-24 2023-08-08 Univ Indiana Res & Tech Corp Profármacos de insulina a base de amida lipídica
JP6657230B2 (ja) 2014-09-24 2020-03-04 インディアナ ユニヴァーシティ リサーチ アンド テクノロジー コーポレイション インクレチン−インスリンコンジュゲート

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3903068A (en) * 1972-12-26 1975-09-02 Us Health Education & Welfare Facile synthesis of human insulin by modification of porcine insulin
JPS55138393A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd Semisynthesis of insulin
NO153061C (no) * 1979-04-13 1986-01-08 Shionogi & Co Fremgangsmaate for fremstilling av et b30-threonininsulin
JPS55138391A (en) * 1979-04-13 1980-10-29 Shionogi & Co Ltd New synthetic method of peptide derivative
DK147437A (en) * 1980-02-11 1900-01-01 Process for preparing human insulin or threonine B30 esters of human insulin, or a salt or complex thereof
US4421685A (en) * 1980-03-27 1983-12-20 Eli Lilly And Company Process for producing an insulin
DK319780A (da) * 1980-07-24 1982-01-25 Forenede Bryggerier As Fremgangsmaade til enzymatisk udskiftning af b-30 aminosyren i insuliner
IE52768B1 (en) * 1981-04-06 1988-02-17 Boots Co Ltd 1-arylcyclobutylalkylamine compounds useful as therapeutic agents
DE3327709A1 (de) * 1983-07-29 1985-02-07 Hoechst Ag, 6230 Frankfurt Insulin-derivat-kristallsuspensionen, verfahren zu deren herstellung und deren verwendung
DK113585D0 (da) * 1985-03-12 1985-03-12 Novo Industri As Nye peptider

Also Published As

Publication number Publication date
NO174278B (no) 1994-01-03
DK159856B (da) 1990-12-17
DK159856C (da) 1991-05-06
US5028586A (en) 1991-07-02
FI864560A0 (fi) 1986-11-10
EP0216833B1 (de) 1993-01-13
FI864559A (fi) 1986-11-10
FI93460C (fi) 1995-04-10
NO864555D0 (no) 1986-11-14
NO864555L (no) 1986-11-14
DK545686D0 (da) 1986-11-14
WO1986005497A1 (en) 1986-09-25
IL78160A0 (en) 1986-07-31
NO864556D0 (no) 1986-11-14
WO1986005496A1 (en) 1986-09-25
EP0216833A1 (de) 1987-04-08
IL78160A (en) 1991-06-10
NO864556L (no) 1986-11-14
FI93460B (fi) 1994-12-30
EP0216832A1 (de) 1987-04-08
DE3673737D1 (de) 1990-10-04
AU5622786A (en) 1986-10-13
FI864560A (fi) 1986-11-10
DK545686A (da) 1986-11-14
DK119785D0 (da) 1985-03-15
DE3687500D1 (de) 1993-02-25
AU596968B2 (en) 1990-05-24
ATE84546T1 (de) 1993-01-15
JPS62502538A (ja) 1987-10-01
JPS62502196A (ja) 1987-08-27
DK545786A (da) 1986-11-14
NO174278C (no) 1994-04-13
EP0216832B1 (de) 1990-08-29
AU5622686A (en) 1986-10-13
IL78161A0 (en) 1986-07-31
DK545786D0 (da) 1986-11-14
DE3687500T2 (de) 1993-07-01
ATE56022T1 (de) 1990-09-15

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Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: NORDISK GENTOFTE