FI844406L - Pyrimidoisokinolinderivat. - Google Patents

Pyrimidoisokinolinderivat.

Info

Publication number
FI844406L
FI844406L FI844406A FI844406A FI844406L FI 844406 L FI844406 L FI 844406L FI 844406 A FI844406 A FI 844406A FI 844406 A FI844406 A FI 844406A FI 844406 L FI844406 L FI 844406L
Authority
FI
Finland
Prior art keywords
pyrimidoisokinolinderivat
Prior art date
Application number
FI844406A
Other languages
English (en)
Other versions
FI77034B (fi
FI844406A0 (fi
FI77034C (fi
Inventor
Ikuo Ueda
Youichi Shiokawa
Takashi Manabe
Original Assignee
Fujisawa Pharmaceutical Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from GB838331228A external-priority patent/GB8331228D0/en
Priority claimed from GB848405776A external-priority patent/GB8405776D0/en
Priority claimed from GB848425791A external-priority patent/GB8425791D0/en
Application filed by Fujisawa Pharmaceutical Co filed Critical Fujisawa Pharmaceutical Co
Publication of FI844406A0 publication Critical patent/FI844406A0/fi
Publication of FI844406L publication Critical patent/FI844406L/fi
Publication of FI77034B publication Critical patent/FI77034B/fi
Application granted granted Critical
Publication of FI77034C publication Critical patent/FI77034C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P11/00—Drugs for disorders of the respiratory system
    • A61P11/06—Antiasthmatics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
    • C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
    • C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
    • C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
    • C07D471/04—Ortho-condensed systems
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
    • Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
    • Y02P20/00—Technologies relating to chemical industry
    • Y02P20/50—Improvements relating to the production of bulk chemicals
    • Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Pulmonology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Plural Heterocyclic Compounds (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI844406A 1983-11-23 1984-11-09 Foerfarande foer framstaellning av farmakologiskt vaerdefulla 4-oxo-4h-pyrimido/2,1-a/isokinolin-3- karboxylsyraderivat. FI77034C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
GB838331228A GB8331228D0 (en) 1983-11-23 1983-11-23 Pyrimidoisoquinoline derivatives
GB8331228 1983-11-23
GB848405776A GB8405776D0 (en) 1984-03-06 1984-03-06 Pyrimidoisoquinoline derivatives
GB8405776 1984-03-06
GB8425791 1984-10-12
GB848425791A GB8425791D0 (en) 1984-10-12 1984-10-12 Pyrimidoisoquinoline derivatives

Publications (4)

Publication Number Publication Date
FI844406A0 FI844406A0 (fi) 1984-11-09
FI844406L true FI844406L (fi) 1985-05-24
FI77034B FI77034B (fi) 1988-09-30
FI77034C FI77034C (fi) 1989-01-10

Family

ID=27262222

Family Applications (1)

Application Number Title Priority Date Filing Date
FI844406A FI77034C (fi) 1983-11-23 1984-11-09 Foerfarande foer framstaellning av farmakologiskt vaerdefulla 4-oxo-4h-pyrimido/2,1-a/isokinolin-3- karboxylsyraderivat.

Country Status (17)

Country Link
US (1) US4673676A (fi)
EP (1) EP0143001B1 (fi)
KR (2) KR920008168B1 (fi)
AR (1) AR243889A1 (fi)
AT (1) ATE62484T1 (fi)
AU (1) AU582554B2 (fi)
CA (1) CA1232605A (fi)
DE (1) DE3484420D1 (fi)
DK (1) DK165789C (fi)
ES (2) ES8602786A1 (fi)
FI (1) FI77034C (fi)
GR (1) GR81006B (fi)
HU (1) HU202528B (fi)
IL (1) IL73586A (fi)
NO (1) NO162019C (fi)
PH (1) PH22068A (fi)
SU (1) SU1512482A3 (fi)

Families Citing this family (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US4661592A (en) * 1984-06-27 1987-04-28 G. D. Searle & Co. 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives
WO2009094528A1 (en) 2008-01-25 2009-07-30 High Point Pharmaceuticals, Llc TRICYCLIC COMPOUNDS AS MODULATORS OF TNF-α SYNTHESIS AND AS PDE4 INHIBITORS

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3876788A (en) * 1970-08-27 1975-04-08 Burroughs Wellcome Co Heterocyclic compounds in the treatment of inflammatory of arthritic conditions
US4017625A (en) * 1975-08-01 1977-04-12 Pfizer Inc. Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor
HU173438B (hu) * 1975-11-27 1979-05-28 Chinoin Gyogyszer Es Vegyeszet Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom
US4127720A (en) * 1977-09-21 1978-11-28 Bristol-Myers Company Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity
IE51802B1 (en) * 1979-12-03 1987-04-01 Fujisawa Pharmaceutical Co Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them
JPS59172472A (ja) * 1983-03-18 1984-09-29 Fujisawa Pharmaceut Co Ltd イソキノリン誘導体およびその塩類、それらの製造法ならびにそれらを有効成分とする抗アレルギ−剤
JPS59172490A (ja) * 1983-03-18 1984-09-29 Fujisawa Pharmaceut Co Ltd ピリミドイソキノリン誘導体およびその塩類、それらの製造法ならびにそれらを有効成分とする抗アレルギ−剤
NO162019C (no) * 1983-11-23 1989-10-25 Fujisawa Pharmaceutical Co Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater.
US4661592A (en) * 1984-06-27 1987-04-28 G. D. Searle & Co. 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives

Also Published As

Publication number Publication date
FI77034B (fi) 1988-09-30
EP0143001A2 (en) 1985-05-29
NO162019C (no) 1989-10-25
US4673676A (en) 1987-06-16
AU3540584A (en) 1985-05-30
GR81006B (en) 1985-01-03
HU202528B (en) 1991-03-28
NO162019B (no) 1989-07-17
DK165789B (da) 1993-01-18
IL73586A0 (en) 1985-02-28
DK536184D0 (da) 1984-11-09
PH22068A (en) 1988-05-20
HUT35674A (en) 1985-07-29
ES546222A0 (es) 1986-01-16
SU1512482A3 (ru) 1989-09-30
DK165789C (da) 1993-06-14
AU582554B2 (en) 1989-04-06
DK536184A (da) 1985-05-24
ES537928A0 (es) 1985-12-01
EP0143001A3 (en) 1986-03-19
NO844466L (no) 1985-05-24
AR243889A1 (es) 1993-09-30
FI844406A0 (fi) 1984-11-09
ES8602786A1 (es) 1985-12-01
KR920001673B1 (ko) 1992-02-22
DE3484420D1 (en) 1991-05-16
KR850003538A (ko) 1985-06-20
FI77034C (fi) 1989-01-10
ATE62484T1 (de) 1991-04-15
ES8604220A1 (es) 1986-01-16
EP0143001B1 (en) 1991-04-10
KR920008168B1 (ko) 1992-09-24
CA1232605A (en) 1988-02-09
IL73586A (en) 1988-12-30

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: FUJISAWA PHARMACEUTICAL CO., LTD