DK165789C - 4-oxo-4h-pyrimidooe2,1,aaaisoquinolinderivater, analogifremgangsmaade til fremstilling deraf, farmaceutisk praeparat indeholdende disse samt derivaterne til anvendelse som antiallergisk middel - Google Patents
4-oxo-4h-pyrimidooe2,1,aaaisoquinolinderivater, analogifremgangsmaade til fremstilling deraf, farmaceutisk praeparat indeholdende disse samt derivaterne til anvendelse som antiallergisk middelInfo
- Publication number
- DK165789C DK165789C DK536184A DK536184A DK165789C DK 165789 C DK165789 C DK 165789C DK 536184 A DK536184 A DK 536184A DK 536184 A DK536184 A DK 536184A DK 165789 C DK165789 C DK 165789C
- Authority
- DK
- Denmark
- Prior art keywords
- derivatives
- aaaisoquinoline
- oxo
- preparing
- analysis
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P11/00—Drugs for disorders of the respiratory system
- A61P11/06—Antiasthmatics
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/02—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines
- C07D217/08—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with only hydrogen atoms or radicals containing only carbon and hydrogen atoms, directly attached to carbon atoms of the nitrogen-containing ring; Alkylene-bis-isoquinolines with a hetero atom directly attached to the ring nitrogen atom
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D217/00—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems
- C07D217/22—Heterocyclic compounds containing isoquinoline or hydrogenated isoquinoline ring systems with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to carbon atoms of the nitrogen-containing ring
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D471/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00
- C07D471/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, at least one ring being a six-membered ring with one nitrogen atom, not provided for by groups C07D451/00 - C07D463/00 in which the condensed system contains two hetero rings
- C07D471/04—Ortho-condensed systems
-
- Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
- Y02—TECHNOLOGIES OR APPLICATIONS FOR MITIGATION OR ADAPTATION AGAINST CLIMATE CHANGE
- Y02P—CLIMATE CHANGE MITIGATION TECHNOLOGIES IN THE PRODUCTION OR PROCESSING OF GOODS
- Y02P20/00—Technologies relating to chemical industry
- Y02P20/50—Improvements relating to the production of bulk chemicals
- Y02P20/55—Design of synthesis routes, e.g. reducing the use of auxiliary or protecting groups
Applications Claiming Priority (6)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| GB8331228 | 1983-11-23 | ||
| GB838331228A GB8331228D0 (en) | 1983-11-23 | 1983-11-23 | Pyrimidoisoquinoline derivatives |
| GB8405776 | 1984-03-06 | ||
| GB848405776A GB8405776D0 (en) | 1984-03-06 | 1984-03-06 | Pyrimidoisoquinoline derivatives |
| GB8425791 | 1984-10-12 | ||
| GB848425791A GB8425791D0 (en) | 1984-10-12 | 1984-10-12 | Pyrimidoisoquinoline derivatives |
Publications (4)
| Publication Number | Publication Date |
|---|---|
| DK536184D0 DK536184D0 (da) | 1984-11-09 |
| DK536184A DK536184A (da) | 1985-05-24 |
| DK165789B DK165789B (da) | 1993-01-18 |
| DK165789C true DK165789C (da) | 1993-06-14 |
Family
ID=27262222
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| DK536184A DK165789C (da) | 1983-11-23 | 1984-11-09 | 4-oxo-4h-pyrimidooe2,1,aaaisoquinolinderivater, analogifremgangsmaade til fremstilling deraf, farmaceutisk praeparat indeholdende disse samt derivaterne til anvendelse som antiallergisk middel |
Country Status (17)
| Country | Link |
|---|---|
| US (1) | US4673676A (da) |
| EP (1) | EP0143001B1 (da) |
| KR (2) | KR920008168B1 (da) |
| AR (1) | AR243889A1 (da) |
| AT (1) | ATE62484T1 (da) |
| AU (1) | AU582554B2 (da) |
| CA (1) | CA1232605A (da) |
| DE (1) | DE3484420D1 (da) |
| DK (1) | DK165789C (da) |
| ES (2) | ES537928A0 (da) |
| FI (1) | FI77034C (da) |
| GR (1) | GR81006B (da) |
| HU (1) | HU202528B (da) |
| IL (1) | IL73586A (da) |
| NO (1) | NO162019C (da) |
| PH (1) | PH22068A (da) |
| SU (1) | SU1512482A3 (da) |
Families Citing this family (3)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| NO162019C (no) * | 1983-11-23 | 1989-10-25 | Fujisawa Pharmaceutical Co | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater. |
| US4661592A (en) * | 1984-06-27 | 1987-04-28 | G. D. Searle & Co. | 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives |
| KR101709141B1 (ko) | 2008-01-25 | 2017-02-22 | 브이티브이 테라퓨틱스 엘엘씨 | ＴＮＦ-α 합성의 조절자 및 ＰＤＥ4 억제제로서 3고리 화합물 |
Family Cites Families (9)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3876788A (en) * | 1970-08-27 | 1975-04-08 | Burroughs Wellcome Co | Heterocyclic compounds in the treatment of inflammatory of arthritic conditions |
| US4017625A (en) * | 1975-08-01 | 1977-04-12 | Pfizer Inc. | Anti-allergic N-(5-tetrazolyl)-1-oxo-1H-6-alkoxypyrimido-[1,2-a]quinoline-2-carboxamides and intermediates therefor |
| HU173438B (hu) * | 1975-11-27 | 1979-05-28 | Chinoin Gyogyszer Es Vegyeszet | Sposob poluchenija novykh proizvodnykh 4-okso-1,6,7,8-/tetragidro-4h-pirido/1,2/pirimidina s zaderzhivajuhhejj vozgoranie aktivnot'ju i protivosvertivajuhhem effektom |
| US4127720A (en) * | 1977-09-21 | 1978-11-28 | Bristol-Myers Company | Pyrimido[2,1-a]isoquinoline derivatives having antiallergy activity |
| IE51802B1 (en) * | 1979-12-03 | 1987-04-01 | Fujisawa Pharmaceutical Co | Quinazoline derivatives,processes for their preparation and pharmaceutical compositions containing them |
| JPS59172472A (ja) * | 1983-03-18 | 1984-09-29 | Fujisawa Pharmaceut Co Ltd | イソキノリン誘導体およびその塩類、それらの製造法ならびにそれらを有効成分とする抗アレルギ−剤 |
| JPS59172490A (ja) * | 1983-03-18 | 1984-09-29 | Fujisawa Pharmaceut Co Ltd | ピリミドイソキノリン誘導体およびその塩類、それらの製造法ならびにそれらを有効成分とする抗アレルギ−剤 |
| NO162019C (no) * | 1983-11-23 | 1989-10-25 | Fujisawa Pharmaceutical Co | Analogifremgangsmaate for fremstilling av terapeutisk aktive pyrimidoiskinolinderivater. |
| US4661592A (en) * | 1984-06-27 | 1987-04-28 | G. D. Searle & Co. | 4H-pyrimido[2,1-a]isoquinolin-4-one derivatives |
-
1984
- 1984-11-08 NO NO844466A patent/NO162019C/no unknown
- 1984-11-09 FI FI844406A patent/FI77034C/fi not_active IP Right Cessation
- 1984-11-09 US US06/669,865 patent/US4673676A/en not_active Expired - Fee Related
- 1984-11-09 DK DK536184A patent/DK165789C/da active
- 1984-11-14 AU AU35405/84A patent/AU582554B2/en not_active Ceased
- 1984-11-19 CA CA000468159A patent/CA1232605A/en not_active Expired
- 1984-11-21 GR GR81006A patent/GR81006B/el unknown
- 1984-11-21 IL IL73586A patent/IL73586A/xx unknown
- 1984-11-22 HU HU844338A patent/HU202528B/hu not_active IP Right Cessation
- 1984-11-22 DE DE8484308109T patent/DE3484420D1/de not_active Expired - Fee Related
- 1984-11-22 EP EP84308109A patent/EP0143001B1/en not_active Expired - Lifetime
- 1984-11-22 AR AR84298701A patent/AR243889A1/es active
- 1984-11-22 KR KR1019840007323A patent/KR920008168B1/ko not_active IP Right Cessation
- 1984-11-22 SU SU843818298A patent/SU1512482A3/ru active
- 1984-11-22 AT AT84308109T patent/ATE62484T1/de not_active IP Right Cessation
- 1984-11-23 ES ES537928A patent/ES537928A0/es active Granted
- 1984-11-23 PH PH31478A patent/PH22068A/en unknown
-
1985
- 1985-08-16 ES ES546222A patent/ES8604220A1/es not_active Expired
-
1991
- 1991-09-25 KR KR1019910016712A patent/KR920001673B1/ko not_active IP Right Cessation
Also Published As
| Publication number | Publication date |
|---|---|
| DK536184A (da) | 1985-05-24 |
| NO162019C (no) | 1989-10-25 |
| DE3484420D1 (en) | 1991-05-16 |
| AU3540584A (en) | 1985-05-30 |
| DK536184D0 (da) | 1984-11-09 |
| FI77034B (fi) | 1988-09-30 |
| DK165789B (da) | 1993-01-18 |
| HUT35674A (en) | 1985-07-29 |
| HU202528B (en) | 1991-03-28 |
| SU1512482A3 (ru) | 1989-09-30 |
| KR920001673B1 (ko) | 1992-02-22 |
| AU582554B2 (en) | 1989-04-06 |
| FI844406A0 (fi) | 1984-11-09 |
| EP0143001B1 (en) | 1991-04-10 |
| ATE62484T1 (de) | 1991-04-15 |
| ES8602786A1 (es) | 1985-12-01 |
| PH22068A (en) | 1988-05-20 |
| KR920008168B1 (ko) | 1992-09-24 |
| IL73586A (en) | 1988-12-30 |
| IL73586A0 (en) | 1985-02-28 |
| FI77034C (fi) | 1989-01-10 |
| ES537928A0 (es) | 1985-12-01 |
| KR850003538A (ko) | 1985-06-20 |
| US4673676A (en) | 1987-06-16 |
| CA1232605A (en) | 1988-02-09 |
| AR243889A1 (es) | 1993-09-30 |
| ES8604220A1 (es) | 1986-01-16 |
| EP0143001A3 (en) | 1986-03-19 |
| NO162019B (no) | 1989-07-17 |
| ES546222A0 (es) | 1986-01-16 |
| NO844466L (no) | 1985-05-24 |
| EP0143001A2 (en) | 1985-05-29 |
| GR81006B (en) | 1985-01-03 |
| FI844406L (fi) | 1985-05-24 |
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