FI841656A0 - Foerfarande foer framstaellning av n- alkylerade dipeptider och deras estrar. - Google Patents

Foerfarande foer framstaellning av n- alkylerade dipeptider och deras estrar.

Info

Publication number
FI841656A0
FI841656A0 FI841656A FI841656A FI841656A0 FI 841656 A0 FI841656 A0 FI 841656A0 FI 841656 A FI841656 A FI 841656A FI 841656 A FI841656 A FI 841656A FI 841656 A0 FI841656 A0 FI 841656A0
Authority
FI
Finland
Prior art keywords
dipeptiders
estrar
alkyles
deras
frequency requirements
Prior art date
Application number
FI841656A
Other languages
English (en)
Other versions
FI841656A (fi
FI80050B (fi
FI80050C (fi
Inventor
Rainer Henning
Hansjoerg Urbach
Original Assignee
Hoechst Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoechst Ag filed Critical Hoechst Ag
Publication of FI841656A0 publication Critical patent/FI841656A0/fi
Publication of FI841656A publication Critical patent/FI841656A/fi
Publication of FI80050B publication Critical patent/FI80050B/fi
Application granted granted Critical
Publication of FI80050C publication Critical patent/FI80050C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K1/00—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length
    • C07K1/06—General methods for the preparation of peptides, i.e. processes for the organic chemical preparation of peptides or proteins of any length using protecting groups or activating agents
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C309/00—Sulfonic acids; Halides, esters, or anhydrides thereof
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06—Dipeptides
    • Y—GENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10—TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10S—TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S530/00—Chemistry: natural resins or derivatives; peptides or proteins; lignins or reaction products thereof
    • Y10S530/80—Antihypertensive peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biophysics (AREA)
  • Biochemistry (AREA)
  • Public Health (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Analytical Chemistry (AREA)
  • Peptides Or Proteins (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Indole Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Other In-Based Heterocyclic Compounds (AREA)
  • Pyrrole Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Thiazole And Isothizaole Compounds (AREA)
  • Hydrogenated Pyridines (AREA)
FI841656A 1983-04-28 1984-04-26 Foerfarande foer framstaellning av n- alkylerade dipeptidfoereningar och en vid foerfarandet anvaendbar mellanprodukt. FI80050C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
DE19833315464 DE3315464A1 (de) 1983-04-28 1983-04-28 Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3315464 1983-04-28

Publications (4)

Publication Number Publication Date
FI841656A0 true FI841656A0 (fi) 1984-04-26
FI841656A FI841656A (fi) 1984-10-29
FI80050B FI80050B (fi) 1989-12-29
FI80050C FI80050C (fi) 1990-04-10

Family

ID=6197624

Family Applications (1)

Application Number Title Priority Date Filing Date
FI841656A FI80050C (fi) 1983-04-28 1984-04-26 Foerfarande foer framstaellning av n- alkylerade dipeptidfoereningar och en vid foerfarandet anvaendbar mellanprodukt.

Country Status (17)

Country Link
US (1) US4525301A (fi)
EP (1) EP0126986B1 (fi)
JP (2) JPH0655757B2 (fi)
KR (1) KR920001771B1 (fi)
AR (1) AR241709A1 (fi)
AT (1) ATE28753T1 (fi)
CA (2) CA1258148A (fi)
DE (2) DE3315464A1 (fi)
DK (2) DK171028B1 (fi)
ES (1) ES8502083A1 (fi)
FI (1) FI80050C (fi)
GR (1) GR81965B (fi)
HU (1) HU194279B (fi)
IE (1) IE57287B1 (fi)
MA (1) MA20104A1 (fi)
NO (1) NO169591C (fi)
PT (1) PT78486B (fi)

Families Citing this family (32)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4766110A (en) * 1981-08-21 1988-08-23 Ryan James W Novel complex amido and imido derivatives of carboxyalkyl peptides
DE3226768A1 (de) * 1981-11-05 1983-05-26 Hoechst Ag, 6230 Frankfurt Derivate der cis, endo-2-azabicyclo-(3.3.0)-octan-3-carbonsaeure, verfahren zu ihrer herstellung, diese enthaltende mittel und deren verwendung
GR78413B (fi) * 1981-12-29 1984-09-27 Hoechst Ag
US5175306A (en) * 1983-01-31 1992-12-29 Hoechst Aktiengesellschaft Process for the resolution of racemates of optically active bicyclic imino-α-carboxylic esters
FI841052A (fi) * 1983-03-16 1984-09-17 Usv Pharma Corp Foereningar foer behandling av blodtryckssjukdomar.
FR2546886B2 (fr) * 1983-06-06 1986-05-16 Adir Derives d'acides isoindoledicarboxyliques, leur preparation et compositions pharmaceutiques les contenant
DE3333455A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung n-alkylierter dipeptide und deren estern
DE3333454A1 (de) * 1983-09-16 1985-04-11 Hoechst Ag, 6230 Frankfurt Verfahren zur herstellung von n-alkylierten dipeptiden und deren estern
DE3408923A1 (de) * 1984-03-12 1985-09-26 Hoechst Ag, 6230 Frankfurt Carboxyalkyldipeptidderivate, verfahren zu deren herstellung, diese enthaltende mittel und deren verwendung
US5684016A (en) * 1984-04-12 1997-11-04 Hoechst Aktiengesellschaft Method of treating cardiac insufficiency
DE3413710A1 (de) * 1984-04-12 1985-10-24 Hoechst Ag, 6230 Frankfurt Verfahren zur behandlung der herzinsuffizienz
EP0190224A1 (en) * 1984-07-30 1986-08-13 Schering Corporation PROCESS FOR THE PREPARATION OF CIS, ENDOOCTAHYDROCYCLOPENTA [b] PYRROLE-2-CARBOXYLATE
US4801721A (en) * 1984-08-16 1989-01-31 Ryan James W Stereospecific synthesis of carboxyalkyl peptides
DE3431541A1 (de) * 1984-08-28 1986-03-06 Hoechst Ag, 6230 Frankfurt Cis,endo-2-azabicycloalkan-3-carbonsaeure-derivate, verfahren zu deren herstellung, deren verwendung sowie zwischenprodukte bei deren herstellung
US4691049A (en) * 1984-09-17 1987-09-01 Schering Corporation Process for preparing a specific diastereomer of a monoamino dicarboxylic acid ester
US4785003A (en) * 1984-10-16 1988-11-15 Biomeasure, Inc. N-disubstituted glycine and B-amino-propionic acid derivatives having anti-ulcer activity
US4785089A (en) * 1985-06-13 1988-11-15 Ciba-Geigy Corporation Novel sulfonic acid esters and their preparation
DE3582595D1 (de) * 1985-09-16 1991-05-23 Schering Corp Antihypertensive mittel, deren pharmazeutische zusammensetzungen und verfahren zur herstellung von mitteln und zusammensetzungen.
US5231080A (en) * 1985-10-15 1993-07-27 Hoechst Aktiengesellschaft Method for the treatment of atherosclerosis, thrombosis, and peripheral vessel disease
JPH0662671B2 (ja) * 1986-01-17 1994-08-17 株式会社大塚製薬工場 プロリン誘導体
US5231084A (en) * 1986-03-27 1993-07-27 Hoechst Aktiengesellschaft Compounds having a cognition adjuvant action, agents containing them, and the use thereof for the treatment and prophylaxis of cognitive dysfuncitons
DE3633496A1 (de) * 1986-10-02 1988-04-14 Hoechst Ag Kombination von angiotensin-converting-enzyme-hemmern mit calciumantagonisten sowie deren verwendung in arzneimitteln
DE3639879A1 (de) * 1986-11-21 1988-06-01 Hoechst Ag Verfahren zur herstellung von mono-, bi- und tricyclischen aminosaeuren, zwischenprodukte dieses verfahrens sowie ein verfahren zu deren herstellung
DE3722007A1 (de) * 1987-07-03 1989-01-12 Hoechst Ag Verfahren zur herstellung bicyclischer aminocarbonsaeuren, zwischenprodukte dieses verfahrens und deren verwendung
HU904967D0 (en) * 1988-04-22 1991-01-28 Hoechst Ag Process for producing new azabicyclo(3.3.o)octane-3-carboxylic acid-octylesther derivatives
DE3839127A1 (de) * 1988-11-19 1990-05-23 Hoechst Ag Pyrrolidon-2-carbonsaeure-derivate mit psychotroper wirkung
ES2136028B1 (es) * 1997-11-03 2000-07-01 Valles Rodoreda Martin Esteres del acido 2-(r)-fluorosulfoniloxi-4-fenibutirico, procedimiento para su obtencion y procedimiento para su utilizacion en la preparacion de carboxialquildipeptidos.
EP1383741A4 (en) * 2001-03-27 2006-01-04 Ranbaxy Lab Ltd PROCESS FOR THE PREPARATION OF BENAZEPRIL
CA2363658C (en) * 2001-11-21 2005-12-13 Brantford Chemicals Inc. Improved process for the preparation of ramipril
EP1615886A1 (en) * 2003-04-15 2006-01-18 Warner-Lambert Company LLC [c]-fused bicyclic proline derivatives and their use for treating arthritic conditions
ZA200704767B (en) * 2004-11-05 2008-08-27 King Pharmaceuticals Res & Dev Stabilized individually coated ramipril particles, compositions and methods
CN105693817B (zh) 2014-11-27 2020-06-05 西北大学 一类三肽化合物及其制备方法与应用

Family Cites Families (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0046953B1 (de) * 1980-08-30 1989-12-06 Hoechst Aktiengesellschaft Aminosäurederivate, Verfahren zu ihrer Herstellung, diese enthaltende Mittel und deren Verwendung
GB2128984B (en) * 1982-05-12 1985-05-22 Hoffmann La Roche Diaza-bicyclic compounds

Also Published As

Publication number Publication date
US4525301A (en) 1985-06-25
DK89392D0 (da) 1992-07-07
FI841656A (fi) 1984-10-29
IE57287B1 (en) 1992-07-15
DE3465202D1 (en) 1987-09-10
NO169591B (no) 1992-04-06
DK172685B1 (da) 1999-05-31
ATE28753T1 (de) 1987-08-15
KR920001771B1 (ko) 1992-03-02
DE3315464A1 (de) 1984-10-31
JPS59206341A (ja) 1984-11-22
CA1281330C (en) 1991-03-12
HUT34224A (en) 1985-02-28
DK213184D0 (da) 1984-04-27
ES531926A0 (es) 1984-12-16
NO169591C (no) 1992-07-15
KR840009076A (ko) 1984-12-24
FI80050B (fi) 1989-12-29
ES8502083A1 (es) 1984-12-16
JPH06184095A (ja) 1994-07-05
FI80050C (fi) 1990-04-10
DK89392A (da) 1992-07-07
GR81965B (fi) 1984-12-12
MA20104A1 (fr) 1984-12-31
JPH0768213B2 (ja) 1995-07-26
EP0126986A1 (de) 1984-12-05
HU194279B (en) 1988-01-28
CA1258148A (en) 1989-08-01
DK213184A (da) 1984-10-29
EP0126986B1 (de) 1987-08-05
IE841049L (en) 1984-10-28
AR241709A1 (es) 1992-11-30
JPH0655757B2 (ja) 1994-07-27
DK171028B1 (da) 1996-04-22
NO841703L (no) 1984-10-29
PT78486A (de) 1984-05-01
PT78486B (de) 1986-06-02

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Legal Events

Date Code Title Description
MA Patent expired

Owner name: AVENTIS PHARMA DEUTSCHLAND GMBH