FI841590A - Kondenserade sjulemmande ringfoereningar och deras anvaedning. - Google Patents

Kondenserade sjulemmande ringfoereningar och deras anvaedning. Download PDF

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Publication number
FI841590A
FI841590A FI841590A FI841590A FI841590A FI 841590 A FI841590 A FI 841590A FI 841590 A FI841590 A FI 841590A FI 841590 A FI841590 A FI 841590A FI 841590 A FI841590 A FI 841590A
Authority
FI
Finland
Prior art keywords
sup
sjulemmande
ringfoereningar
anvaedning
conditioning
Prior art date
Application number
FI841590A
Other languages
English (en)
Other versions
FI82455C (fi
FI82455B (fi
FI841590A0 (fi
Inventor
Hirosada Sugihara
Kohei Nishikawa
Katsumi Ito
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1983/000127 external-priority patent/WO1984004306A1/ja
Priority claimed from PCT/JP1983/000342 external-priority patent/WO1985001730A1/ja
Priority claimed from PCT/JP1984/000119 external-priority patent/WO1985004402A1/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of FI841590A0 publication Critical patent/FI841590A0/fi
Publication of FI841590A publication Critical patent/FI841590A/fi
Application granted granted Critical
Publication of FI82455B publication Critical patent/FI82455B/fi
Publication of FI82455C publication Critical patent/FI82455C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D209/00—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02—Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44—Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48—Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00—Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/12—Antihypertensives
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D281/00—Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02—Seven-membered rings
    • C07D281/04—Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10—Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D417/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04—Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07K—PEPTIDES
    • C07K5/00—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222—Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00—Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Veterinary Medicine (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Animal Behavior & Ethology (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Public Health (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Cardiology (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • External Artificial Organs (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
FI841590A 1983-04-22 1984-04-19 Foerfarande foer framstaellning av nya, terapeutiskt verksamma bensotiazepinderivat. FI82455C (fi)

Applications Claiming Priority (6)

Application Number Priority Date Filing Date Title
PCT/JP1983/000127 WO1984004306A1 (en) 1983-04-22 1983-04-22 Fused 7-membered ring compounds and process for their preparation
JP8300127 1983-04-22
PCT/JP1983/000342 WO1985001730A1 (en) 1983-10-13 1983-10-13 Fused 7-membered ring compounds and process for their preparation
JP8300342 1983-10-13
PCT/JP1984/000119 WO1985004402A1 (en) 1984-03-24 1984-03-24 Fused 7-membered ring compounds and process for their preparation
JP8400119 1984-03-24

Publications (4)

Publication Number Publication Date
FI841590A0 FI841590A0 (fi) 1984-04-19
FI841590A true FI841590A (fi) 1984-10-23
FI82455B FI82455B (fi) 1990-11-30
FI82455C FI82455C (fi) 1991-03-11

Family

ID=27304084

Family Applications (1)

Application Number Title Priority Date Filing Date
FI841590A FI82455C (fi) 1983-04-22 1984-04-19 Foerfarande foer framstaellning av nya, terapeutiskt verksamma bensotiazepinderivat.

Country Status (17)

Country Link
US (1) US4564612A (fi)
EP (1) EP0125056B1 (fi)
KR (1) KR910007965B1 (fi)
AT (1) ATE60061T1 (fi)
AU (1) AU565188B2 (fi)
CA (1) CA1209993A (fi)
DE (1) DE3483920D1 (fi)
ES (2) ES8602699A1 (fi)
FI (1) FI82455C (fi)
GR (1) GR79905B (fi)
HU (1) HU193008B (fi)
IE (1) IE57599B1 (fi)
IL (1) IL71617A (fi)
NO (1) NO162235C (fi)
NZ (1) NZ207915A (fi)
PH (1) PH21294A (fi)
PT (1) PT78454B (fi)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE3423743A1 (de) * 1983-06-29 1985-01-10 Mitsui Toatsu Chemicals, Inc., Tokio/Tokyo Benzothiazepin-derivate und verfahren zu ihrer herstellung
AU570710B2 (en) * 1983-08-12 1988-03-24 Takeda Chemical Industries Ltd. 4-oxo-2, 3, 4, 5-tetrahydro-1, 5-benzoxazepine derivatives
US4512988A (en) * 1984-03-01 1985-04-23 E. R. Squibb & Sons, Inc. Acylamino oxo or hydroxy substituted alkylamino thiazines and thiazepines
NO160712C (no) * 1984-03-24 1989-05-24 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepin-forbindelser.
EP0187037A3 (en) * 1984-12-21 1988-03-23 Takeda Chemical Industries, Ltd. Piperidine derivatives, their production and use
US4692522A (en) * 1985-04-01 1987-09-08 Merck & Co., Inc. Benzofused lactams useful as cholecystokinin antagonists
JPH0657707B2 (ja) * 1987-05-25 1994-08-03 吉富製薬株式会社 ピペリジン化合物
JPS6450872A (en) * 1987-08-21 1989-02-27 Tanabe Seiyaku Co Production of 1,5-benzothiazepine derivative
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
US5290927A (en) * 1988-03-01 1994-03-01 Ajinomoto Co., Inc. Process for preparing 2',3'-dideoxyadenosine
AT393998B (de) * 1990-02-16 1992-01-10 Troendle Peter Paul Buch
AU4282993A (en) * 1992-07-01 1994-01-31 Pfizer Inc. Benzothiazepine and benzoxazepine derivatives as cholecystokinin receptor antagonists
ZA941003B (en) * 1993-02-15 1995-08-14 Wellcome Found Hypolipidaemic compounds
ZA956647B (en) * 1994-08-10 1997-02-10 Wellcome Found Hypolipidaemic compounds.
FR2781483A1 (fr) * 1998-07-21 2000-01-28 Hoechst Marion Roussel Inc Derives de thioazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicament et compositions pharmaceutiques les renfermant
FR2807039A1 (fr) * 2000-03-31 2001-10-05 Adir NOUVEAU PROCEDE DE PREPARATION DE LA 11-AMINO-3-CHLORO-6,11- DIHYDRO-5,5-DIOXO-6-METHYL-DIBENZO[c,f][1,2]-THIAZEPINE ET APPLICATION A LA SYNTHESE DE LA TIANEPTINE

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341519A (en) * 1965-04-28 1967-09-12 Squibb & Sons Inc Novel benzoxazines, benzothiazines, benzoxazepins and benzothiazepins
AU543804B2 (en) * 1980-10-31 1985-05-02 Takeda Chemical Industries Ltd. Amides having bicyclic substituents on nitrogen
DE3260505D1 (en) * 1981-01-23 1984-09-13 Takeda Chemical Industries Ltd Alicyclic compounds, their production and use
DE3260831D1 (en) * 1981-06-05 1984-10-31 Merck & Co Inc Perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives, process for preparing and pharmceutical composition containing the same
GB2103614B (en) * 1981-08-11 1984-11-21 Ciba Geigy Ag Benzazepin-2-ones
JPS5829779A (ja) * 1981-08-17 1983-02-22 Nippon Iyakuhin Kogyo Kk Ｎ−アミノアルキル−１，５−ベンゾチアゼピン誘導体の製造法
US4477464A (en) * 1983-02-10 1984-10-16 Ciba-Geigy Corporation Hetero-benzazepine derivatives and their pharmaceutical use
US4460579A (en) * 1983-02-28 1984-07-17 E. R. Squibb & Sons, Inc. Thiazine and thiazepine containing compounds
DE3423743A1 (de) * 1983-06-29 1985-01-10 Mitsui Toatsu Chemicals, Inc., Tokio/Tokyo Benzothiazepin-derivate und verfahren zu ihrer herstellung

Also Published As

Publication number Publication date
KR910007965B1 (ko) 1991-10-04
IL71617A (en) 1988-05-31
EP0125056B1 (en) 1991-01-16
US4564612A (en) 1986-01-14
NO841555L (no) 1984-10-23
EP0125056A2 (en) 1984-11-14
EP0125056A3 (en) 1986-04-16
NO162235B (no) 1989-08-21
PT78454A (en) 1984-05-01
ES544748A0 (es) 1986-07-16
GR79905B (fi) 1984-10-31
FI82455C (fi) 1991-03-11
KR840008346A (ko) 1984-12-14
ES531740A0 (es) 1985-12-01
DE3483920D1 (de) 1991-02-21
IE57599B1 (en) 1993-01-27
AU2709284A (en) 1984-10-25
NO162235C (no) 1989-11-29
PT78454B (en) 1986-08-28
IE840927L (en) 1984-10-22
ATE60061T1 (de) 1991-02-15
ES8609290A1 (es) 1986-07-16
PH21294A (en) 1987-09-28
CA1209993A (en) 1986-08-19
ES8602699A1 (es) 1985-12-01
FI82455B (fi) 1990-11-30
IL71617A0 (fi) 1984-07-31
NZ207915A (en) 1986-10-08
AU565188B2 (en) 1987-09-10
HUT34176A (en) 1985-02-28
HU193008B (en) 1987-08-28
FI841590A0 (fi) 1984-04-19

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Owner name: TAKEDA CHEMICAL INDUSTRIES, LTD.