ES544748A0 - Procedimiento para preparar cetonas heterociclicas nitroge- nadas con anillo de siete miembros y condensadas - Google Patents

Procedimiento para preparar cetonas heterociclicas nitroge- nadas con anillo de siete miembros y condensadas

Info

Publication number
ES544748A0
ES544748A0 ES544748A ES544748A ES544748A0 ES 544748 A0 ES544748 A0 ES 544748A0 ES 544748 A ES544748 A ES 544748A ES 544748 A ES544748 A ES 544748A ES 544748 A0 ES544748 A0 ES 544748A0
Authority
ES
Spain
Prior art keywords
sup
nitrogenated
preparing
procedure
condensed ring
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
ES544748A
Other languages
English (en)
Other versions
ES8609290A1 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Takeda Pharmaceutical Co Ltd
Original Assignee
Takeda Chemical Industries Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from PCT/JP1983/000127 external-priority patent/WO1984004306A1/ja
Priority claimed from PCT/JP1983/000342 external-priority patent/WO1985001730A1/ja
Priority claimed from PCT/JP1984/000119 external-priority patent/WO1985004402A1/ja
Application filed by Takeda Chemical Industries Ltd filed Critical Takeda Chemical Industries Ltd
Publication of ES544748A0 publication Critical patent/ES544748A0/es
Publication of ES8609290A1 publication Critical patent/ES8609290A1/es
Expired legal-status Critical Current

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D209/00Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom
    • C07D209/02Heterocyclic compounds containing five-membered rings, condensed with other rings, with one nitrogen atom as the only ring hetero atom condensed with one carbocyclic ring
    • C07D209/44Iso-indoles; Hydrogenated iso-indoles
    • C07D209/48Iso-indoles; Hydrogenated iso-indoles with oxygen atoms in positions 1 and 3, e.g. phthalimide
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P43/00Drugs for specific purposes, not provided for in groups A61P1/00-A61P41/00
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/12Antihypertensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D281/00Heterocyclic compounds containing rings of more than six members having one nitrogen atom and one sulfur atom as the only ring hetero atoms
    • C07D281/02Seven-membered rings
    • C07D281/04Seven-membered rings having the hetero atoms in positions 1 and 4
    • C07D281/08Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems
    • C07D281/10Seven-membered rings having the hetero atoms in positions 1 and 4 condensed with carbocyclic rings or ring systems condensed with one six-membered ring
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D417/00Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00
    • C07D417/02Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings
    • C07D417/04Heterocyclic compounds containing two or more hetero rings, at least one ring having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by group C07D415/00 containing two hetero rings directly linked by a ring-member-to-ring-member bond
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • C07K5/0222Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2 with the first amino acid being heterocyclic, e.g. Pro, Trp
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • General Chemical & Material Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Animal Behavior & Ethology (AREA)
  • Engineering & Computer Science (AREA)
  • Biochemistry (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Biophysics (AREA)
  • Genetics & Genomics (AREA)
  • Molecular Biology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen- Or Sulfur-Containing Heterocyclic Ring Compounds With Rings Of Six Or More Members (AREA)
  • Saccharide Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Low-Molecular Organic Synthesis Reactions Using Catalysts (AREA)
  • External Artificial Organs (AREA)
ES544748A 1983-04-22 1985-07-01 Procedimiento para preparar cetonas heterociclicas nitroge- nadas con anillo de siete miembros y condensadas Expired ES8609290A1 (es)

Applications Claiming Priority (3)

Application Number Priority Date Filing Date Title
PCT/JP1983/000127 WO1984004306A1 (en) 1983-04-22 1983-04-22 Fused 7-membered ring compounds and process for their preparation
PCT/JP1983/000342 WO1985001730A1 (en) 1983-10-13 1983-10-13 Fused 7-membered ring compounds and process for their preparation
PCT/JP1984/000119 WO1985004402A1 (en) 1984-03-24 1984-03-24 Fused 7-membered ring compounds and process for their preparation

Publications (2)

Publication Number Publication Date
ES544748A0 true ES544748A0 (es) 1986-07-16
ES8609290A1 ES8609290A1 (es) 1986-07-16

Family

ID=27304084

Family Applications (2)

Application Number Title Priority Date Filing Date
ES531740A Expired ES8602699A1 (es) 1983-04-22 1984-04-18 Procedimiento para preparar cetonas heterociclicas nitrogenadas con anillo de siete miembros y condensadas.
ES544748A Expired ES8609290A1 (es) 1983-04-22 1985-07-01 Procedimiento para preparar cetonas heterociclicas nitroge- nadas con anillo de siete miembros y condensadas

Family Applications Before (1)

Application Number Title Priority Date Filing Date
ES531740A Expired ES8602699A1 (es) 1983-04-22 1984-04-18 Procedimiento para preparar cetonas heterociclicas nitrogenadas con anillo de siete miembros y condensadas.

Country Status (17)

Country Link
US (1) US4564612A (es)
EP (1) EP0125056B1 (es)
KR (1) KR910007965B1 (es)
AT (1) ATE60061T1 (es)
AU (1) AU565188B2 (es)
CA (1) CA1209993A (es)
DE (1) DE3483920D1 (es)
ES (2) ES8602699A1 (es)
FI (1) FI82455C (es)
GR (1) GR79905B (es)
HU (1) HU193008B (es)
IE (1) IE57599B1 (es)
IL (1) IL71617A (es)
NO (1) NO162235C (es)
NZ (1) NZ207915A (es)
PH (1) PH21294A (es)
PT (1) PT78454B (es)

Families Citing this family (16)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
IT1176345B (it) * 1983-06-29 1987-08-18 Mitsui Toatsu Chemicals Derivati benzotiazepinici e loro metodo di preparazione
AU570710B2 (en) * 1983-08-12 1988-03-24 Takeda Chemical Industries Ltd. 4-oxo-2, 3, 4, 5-tetrahydro-1, 5-benzoxazepine derivatives
US4512988A (en) * 1984-03-01 1985-04-23 E. R. Squibb & Sons, Inc. Acylamino oxo or hydroxy substituted alkylamino thiazines and thiazepines
NO160712C (no) * 1984-03-24 1989-05-24 Takeda Chemical Industries Ltd Analogifremgangsmaate for fremstilling av terapeutisk aktive benzotiazepin-forbindelser.
EP0187037A3 (en) * 1984-12-21 1988-03-23 Takeda Chemical Industries, Ltd. Piperidine derivatives, their production and use
US4692522A (en) * 1985-04-01 1987-09-08 Merck & Co., Inc. Benzofused lactams useful as cholecystokinin antagonists
JPH0657707B2 (ja) * 1987-05-25 1994-08-03 吉富製薬株式会社 ピペリジン化合物
JPS6450872A (en) * 1987-08-21 1989-02-27 Tanabe Seiyaku Co Production of 1,5-benzothiazepine derivative
EP0322779A3 (en) * 1987-12-29 1991-05-08 Yoshitomi Pharmaceutical Industries, Ltd. Benzolactam compounds and pharmaceutical uses thereof
US5290927A (en) * 1988-03-01 1994-03-01 Ajinomoto Co., Inc. Process for preparing 2',3'-dideoxyadenosine
AT393998B (de) * 1990-02-16 1992-01-10 Troendle Peter Paul Buch
JP2655754B2 (ja) * 1992-07-01 1997-09-24 フアイザー・インコーポレイテツド コレシストキニンレセプター拮抗剤としてのベンゾチアゼピン及びベンゾオキサゼピンの誘導体
IL108633A (en) * 1993-02-15 1998-07-15 Wellcome Found History of Benzothiazepine Hypolipidemic Preparation and Pharmaceutical Preparations Containing Them
ZA956647B (en) * 1994-08-10 1997-02-10 Wellcome Found Hypolipidaemic compounds.
FR2781483A1 (fr) * 1998-07-21 2000-01-28 Hoechst Marion Roussel Inc Derives de thioazepinone, procede de preparation et intermediaires de ce procede, application a titre de medicament et compositions pharmaceutiques les renfermant
FR2807039A1 (fr) * 2000-03-31 2001-10-05 Adir NOUVEAU PROCEDE DE PREPARATION DE LA 11-AMINO-3-CHLORO-6,11- DIHYDRO-5,5-DIOXO-6-METHYL-DIBENZO[c,f][1,2]-THIAZEPINE ET APPLICATION A LA SYNTHESE DE LA TIANEPTINE

Family Cites Families (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3341519A (en) * 1965-04-28 1967-09-12 Squibb & Sons Inc Novel benzoxazines, benzothiazines, benzoxazepins and benzothiazepins
AU543804B2 (en) * 1980-10-31 1985-05-02 Takeda Chemical Industries Ltd. Amides having bicyclic substituents on nitrogen
DE3260505D1 (en) * 1981-01-23 1984-09-13 Takeda Chemical Industries Ltd Alicyclic compounds, their production and use
EP0068173B1 (en) * 1981-06-05 1984-09-26 Merck & Co. Inc. Perhydro-1,4-thiazepin-5-one and perhydro-1,4-thiazocin-5-one derivatives, process for preparing and pharmceutical composition containing the same
EP0072352B1 (de) * 1981-08-11 1986-03-05 Ciba-Geigy Ag Benzazepin-2-one, Verfahren zu ihrer Herstellung, pharmazeutische Präparate die diese Verbindungen enthalten, sowie die Verbindungen zur therapeutischen Verwendung
JPS5829779A (ja) * 1981-08-17 1983-02-22 Nippon Iyakuhin Kogyo Kk N−アミノアルキル−1,5−ベンゾチアゼピン誘導体の製造法
US4477464A (en) * 1983-02-10 1984-10-16 Ciba-Geigy Corporation Hetero-benzazepine derivatives and their pharmaceutical use
US4460579A (en) * 1983-02-28 1984-07-17 E. R. Squibb & Sons, Inc. Thiazine and thiazepine containing compounds
IT1176345B (it) * 1983-06-29 1987-08-18 Mitsui Toatsu Chemicals Derivati benzotiazepinici e loro metodo di preparazione

Also Published As

Publication number Publication date
GR79905B (es) 1984-10-31
AU565188B2 (en) 1987-09-10
NO162235B (no) 1989-08-21
HUT34176A (en) 1985-02-28
IE840927L (en) 1984-10-22
PH21294A (en) 1987-09-28
KR840008346A (ko) 1984-12-14
AU2709284A (en) 1984-10-25
IL71617A0 (es) 1984-07-31
ES531740A0 (es) 1985-12-01
EP0125056A2 (en) 1984-11-14
NZ207915A (en) 1986-10-08
CA1209993A (en) 1986-08-19
ATE60061T1 (de) 1991-02-15
KR910007965B1 (ko) 1991-10-04
IL71617A (en) 1988-05-31
DE3483920D1 (de) 1991-02-21
FI82455B (fi) 1990-11-30
EP0125056A3 (en) 1986-04-16
NO162235C (no) 1989-11-29
NO841555L (no) 1984-10-23
PT78454A (en) 1984-05-01
ES8602699A1 (es) 1985-12-01
HU193008B (en) 1987-08-28
FI841590A0 (fi) 1984-04-19
FI841590A (fi) 1984-10-23
PT78454B (en) 1986-08-28
US4564612A (en) 1986-01-14
ES8609290A1 (es) 1986-07-16
FI82455C (fi) 1991-03-11
EP0125056B1 (en) 1991-01-16
IE57599B1 (en) 1993-01-27

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970519