FI83873C - Foerfarande foer framstaellning av hydantoinderivat foer anvaendning som laekemedel. - Google Patents

Foerfarande foer framstaellning av hydantoinderivat foer anvaendning som laekemedel. Download PDF

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Publication number
FI83873C
FI83873C FI850302A FI850302A FI83873C FI 83873 C FI83873 C FI 83873C FI 850302 A FI850302 A FI 850302A FI 850302 A FI850302 A FI 850302A FI 83873 C FI83873 C FI 83873C
Authority
FI
Finland
Prior art keywords
group
formula
compound
dione
spiro
Prior art date
Application number
FI850302A
Other languages
English (en)
Finnish (fi)
Other versions
FI850302A0 (fi
FI850302L (fi
FI83873B (fi
Inventor
Norio Minami
Masayuki Mathukura
Koichiro Ueda
Satoru Tanaka
Toshiji Igarashi
Original Assignee
Eisai Co Ltd
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Eisai Co Ltd filed Critical Eisai Co Ltd
Publication of FI850302A0 publication Critical patent/FI850302A0/fi
Publication of FI850302L publication Critical patent/FI850302L/fi
Application granted granted Critical
Publication of FI83873B publication Critical patent/FI83873B/fi
Publication of FI83873C publication Critical patent/FI83873C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C07D491/107—Spiro-condensed systems with only one oxygen atom as ring hetero atom in the oxygen-containing ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/04—Inotropic agents, i.e. stimulants of cardiac contraction; Drugs for heart failure
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00—Drugs for disorders of the cardiovascular system
    • A61P9/06—Antiarrhythmics
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D407/00—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00
    • C07D407/02—Heterocyclic compounds containing two or more hetero rings, at least one ring having oxygen atoms as the only ring hetero atoms, not provided for by group C07D405/00 containing two hetero rings

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Animal Behavior & Ethology (AREA)
  • Medicinal Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • General Chemical & Material Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Hospice & Palliative Care (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Heterocyclic Carbon Compounds Containing A Hetero Ring Having Oxygen Or Sulfur (AREA)
FI850302A 1984-01-30 1985-01-23 Foerfarande foer framstaellning av hydantoinderivat foer anvaendning som laekemedel. FI83873C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
JP59013442A JPS60158190A (ja) 1984-01-30 1984-01-30 ヒダントイン誘導体およびその製法ならびにそれを含有する医薬
JP1344284 1984-01-30

Publications (4)

Publication Number Publication Date
FI850302A0 FI850302A0 (fi) 1985-01-23
FI850302L FI850302L (fi) 1985-07-31
FI83873B FI83873B (fi) 1991-05-31
FI83873C true FI83873C (fi) 1991-09-10

Family

ID=11833246

Family Applications (1)

Application Number Title Priority Date Filing Date
FI850302A FI83873C (fi) 1984-01-30 1985-01-23 Foerfarande foer framstaellning av hydantoinderivat foer anvaendning som laekemedel.

Country Status (23)

Country Link
US (1) US4650798A (is")
JP (1) JPS60158190A (is")
KR (1) KR870001681B1 (is")
AU (1) AU585207B2 (is")
BE (1) BE901591A (is")
CA (1) CA1249271A (is")
CH (1) CH662354A5 (is")
DE (1) DE3503074A1 (is")
DK (1) DK158668C (is")
ES (2) ES8605523A1 (is")
FI (1) FI83873C (is")
FR (1) FR2558835B1 (is")
GB (1) GB2155466B (is")
HU (1) HU194885B (is")
IE (1) IE850136L (is")
IT (1) IT1184144B (is")
MX (1) MX160579A (is")
NL (1) NL8500248A (is")
NZ (1) NZ210979A (is")
PH (1) PH21920A (is")
SE (1) SE462849B (is")
SU (3) SU1468424A3 (is")
ZA (1) ZA85655B (is")

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2708507B2 (ja) * 1988-04-07 1998-02-04 株式会社三和化学研究所 （ｄ）‐６‐フルオロ‐２，３‐ジヒドロ‐２’，５’‐ジオキソ‐スピロ［４Ｈ‐１‐ベンゾピラン‐４，４’‐イミダゾリジン］‐２‐カルボキサミド誘導体、これらの製法及び用途
JPH0276882A (ja) * 1988-06-20 1990-03-16 Eisai Co Ltd 光学活性ヒダントイン誘導体
IL96507A0 (en) * 1989-12-08 1991-08-16 Merck & Co Inc Nitrogen-containing spirocycles and pharmaceutical compositions containing them
US5206240A (en) * 1989-12-08 1993-04-27 Merck & Co., Inc. Nitrogen-containing spirocycles
GEP20001968B (en) * 1992-01-21 2000-03-05 Glaxo Spa Arilthio Compounds as Antibacterial and Antiviral Agents
US5382587A (en) * 1993-06-30 1995-01-17 Merck & Co., Inc. Spirocycles
US5403846A (en) * 1993-11-22 1995-04-04 Merck & Co., Inc. Spirocycles
US5439914A (en) * 1994-02-18 1995-08-08 Merck & Co., Inc. Spirocycles
GB2355264A (en) * 1999-09-30 2001-04-18 Merck & Co Inc Spirohydantoin derivatives useful as alpha 1a adrenoceptor antagonists

Family Cites Families (1)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2455046A1 (fr) * 1979-04-25 1980-11-21 Science Union & Cie Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament

Also Published As

Publication number Publication date
ES8605523A1 (es) 1986-03-16
SE462849B (sv) 1990-09-10
GB8502308D0 (en) 1985-02-27
US4650798A (en) 1987-03-17
CA1249271A (en) 1989-01-24
GB2155466A (en) 1985-09-25
ES8606293A1 (es) 1986-04-16
HUT38646A (en) 1986-06-30
FR2558835A1 (fr) 1985-08-02
DK39585A (da) 1985-07-31
DK39585D0 (da) 1985-01-29
KR850005442A (ko) 1985-08-26
SU1468424A3 (ru) 1989-03-23
MX160579A (es) 1990-03-27
SU1445559A3 (ru) 1988-12-15
ES539942A0 (es) 1986-03-16
FI850302A0 (fi) 1985-01-23
SE8500387L (sv) 1985-07-31
ZA85655B (en) 1985-08-28
DK158668C (da) 1990-11-26
NZ210979A (en) 1987-05-29
IT1184144B (it) 1987-10-22
IT8519296A0 (it) 1985-01-30
JPS60158190A (ja) 1985-08-19
FR2558835B1 (fr) 1990-05-18
ES548960A0 (es) 1986-04-16
CH662354A5 (fr) 1987-09-30
KR870001681B1 (ko) 1987-09-22
SU1609453A3 (ru) 1990-11-23
DE3503074A1 (de) 1985-08-08
AU3806285A (en) 1985-08-08
AU585207B2 (en) 1989-06-15
FI850302L (fi) 1985-07-31
HU194885B (en) 1988-03-28
SE8500387D0 (sv) 1985-01-28
FI83873B (fi) 1991-05-31
DK158668B (da) 1990-07-02
JPH0441149B2 (is") 1992-07-07
GB2155466B (en) 1987-10-07
IE850136L (en) 1985-07-30
PH21920A (en) 1988-04-08
NL8500248A (nl) 1985-08-16
BE901591A (fr) 1985-07-29

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Legal Events

Date Code Title Description
FA Application withdrawn [patent]

Owner name: EISAI CO., LTD.