FR2455046A1 - Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament - Google Patents

Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament

Info

Publication number
FR2455046A1
FR2455046A1 FR7910440A FR7910440A FR2455046A1 FR 2455046 A1 FR2455046 A1 FR 2455046A1 FR 7910440 A FR7910440 A FR 7910440A FR 7910440 A FR7910440 A FR 7910440A FR 2455046 A1 FR2455046 A1 FR 2455046A1
Authority
FR
France
Prior art keywords
thiochromane
derivs
benzopyran
quinoline
inhibiting activity
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Granted
Application number
FR7910440A
Other languages
English (en)
Other versions
FR2455046B1 (fr
Inventor
Charles Malen
Pierre Roger
Jacques Duhault
Michele Boulanger
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Science Union et Cie
Original Assignee
Science Union et Cie
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Science Union et Cie filed Critical Science Union et Cie
Priority to FR7910440A priority Critical patent/FR2455046A1/fr
Publication of FR2455046A1 publication Critical patent/FR2455046A1/fr
Application granted granted Critical
Publication of FR2455046B1 publication Critical patent/FR2455046B1/fr
Granted legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D491/00—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00
    • C07D491/02—Heterocyclic compounds containing in the condensed ring system both one or more rings having oxygen atoms as the only ring hetero atoms and one or more rings having nitrogen atoms as the only ring hetero atoms, not provided for by groups C07D451/00 - C07D459/00, C07D463/00, C07D477/00 or C07D489/00 in which the condensed system contains two hetero rings
    • C07D491/10—Spiro-condensed systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/02—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D311/74—Benzo[b]pyrans, hydrogenated in the carbocyclic ring
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D311/00—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings
    • C07D311/96—Heterocyclic compounds containing six-membered rings having one oxygen atom as the only hetero atom, condensed with other rings spiro-condensed with carbocyclic rings or ring systems
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D495/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms
    • C07D495/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having sulfur atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D495/10—Spiro-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)

Abstract

L'INVENTION SE RAPPORTE A DES NOUVELLES HYDANTOINES SUBSTITUEES PAR UN HETEROCYCLE BICYCLIQUE. ELLES REPONDENT A LA FORMULE GENERALE I: (CF DESSIN DANS BOPI) DANS LAQUELLE R EST DE L'HYDROGENE OU UN SUBSTITUANT HYDROCARBONE; R ET R SONT DE L'HYDROGENE, UN RADICAL ALCOYLE INFERIEUR, TRIFLUOROMETHYLE OU CYCLOALCOYLENE; A EST LE RESTE D'UN CYCLE BENZENIQUE; Z EST LE GROUPE O, S OU NR. CES COMPOSES PEUVENT ETRE SALIFIES PAR UNE BASE MINERALE OU ORGANIQUE. L'INVENTION CONCERNE EGALEMENT LES COMPOSITIONS PHARMACEUTIQUES RENFERMANT A TITRE DE PRINCIPE ACTIF UN COMPOSE DE FORMULE I OU UN DE SES SELS AVEC UNE BASE. LES COMPOSES SELON L'INVENTION TROUVENT UN EMPLOI COMME MEDICAMENT EN MEDECINE HUMAINE OU ANIMALE.
FR7910440A 1979-04-25 1979-04-25 Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament Granted FR2455046A1 (fr)

Priority Applications (1)

Application Number Priority Date Filing Date Title
FR7910440A FR2455046A1 (fr) 1979-04-25 1979-04-25 Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
FR7910440A FR2455046A1 (fr) 1979-04-25 1979-04-25 Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament

Publications (2)

Publication Number Publication Date
FR2455046A1 true FR2455046A1 (fr) 1980-11-21
FR2455046B1 FR2455046B1 (fr) 1983-06-24

Family

ID=9224705

Family Applications (1)

Application Number Title Priority Date Filing Date
FR7910440A Granted FR2455046A1 (fr) 1979-04-25 1979-04-25 Nouvelles hydantoines, leur procede de preparation et leur emploi comme medicament

Country Status (1)

Country Link
FR (1) FR2455046A1 (fr)

Cited By (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2487353A1 (fr) * 1980-07-21 1982-01-29 Eisai Co Ltd Derives d'hydantoine, leur procede de preparation et leur application therapeutique
FR2558835A1 (fr) * 1984-01-30 1985-08-02 Eisai Co Ltd Derives d'hydantoine, leur procede de production et medicament les contenant
EP0264586A1 (fr) * 1986-08-28 1988-04-27 Sanwa Kagaku Kenkyusho Co., Ltd. Dérivés de l'hydantoine pour le traîtement de complications du diabète
EP0306251A3 (fr) * 1987-09-04 1990-08-01 Pfizer Inc. Dérivés d'azolidinedione
EP0384416A1 (fr) * 1989-02-22 1990-08-29 Sanwa Kagaku Kenkyusho Co., Ltd. Composition pharmaceutique contenant un dérivé d'hydantoine
EP0445950A1 (fr) * 1990-03-07 1991-09-11 Pfizer Inc. Dérivés de pyridine et procédés pour leur synthèse

Cited By (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR2487353A1 (fr) * 1980-07-21 1982-01-29 Eisai Co Ltd Derives d'hydantoine, leur procede de preparation et leur application therapeutique
US4874869A (en) * 1980-07-21 1989-10-17 Eisai Co., Ltd. Hydantoin derivatives and medicines containing the same
FR2558835A1 (fr) * 1984-01-30 1985-08-02 Eisai Co Ltd Derives d'hydantoine, leur procede de production et medicament les contenant
US4650798A (en) * 1984-01-30 1987-03-17 Eisai Co., Ltd. Antiarrhythmic 2,2-dialkyl-1-(aminoalkyl)-spiro[chroman-4,4'-imidazolidine]-2',5'-diones
AU585207B2 (en) * 1984-01-30 1989-06-15 Eisai Co. Ltd. Hydantoin derivatives, process for producing the same and medicine containing the same.
EP0264586A1 (fr) * 1986-08-28 1988-04-27 Sanwa Kagaku Kenkyusho Co., Ltd. Dérivés de l'hydantoine pour le traîtement de complications du diabète
EP0306251A3 (fr) * 1987-09-04 1990-08-01 Pfizer Inc. Dérivés d'azolidinedione
EP0384416A1 (fr) * 1989-02-22 1990-08-29 Sanwa Kagaku Kenkyusho Co., Ltd. Composition pharmaceutique contenant un dérivé d'hydantoine
WO1990009791A1 (fr) * 1989-02-22 1990-09-07 Sanwa Kagaku Kenkyusho Co., Ltd. Preparation pharmaceutique contenant un derive d'hydantoine
EP0445950A1 (fr) * 1990-03-07 1991-09-11 Pfizer Inc. Dérivés de pyridine et procédés pour leur synthèse
US5336771A (en) * 1990-03-07 1994-08-09 Pfizer Inc. Certain 3,4-dihydro-2H-pyrano[2,3-b]pyridines

Also Published As

Publication number Publication date
FR2455046B1 (fr) 1983-06-24

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Legal Events

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