FI833417A0 - Carbapenemantibiotika - Google Patents

Carbapenemantibiotika

Info

Publication number
FI833417A0
FI833417A0 FI833417A FI833417A FI833417A0 FI 833417 A0 FI833417 A0 FI 833417A0 FI 833417 A FI833417 A FI 833417A FI 833417 A FI833417 A FI 833417A FI 833417 A0 FI833417 A0 FI 833417A0
Authority
FI
Finland
Prior art keywords
carbapenemantibiotika
Prior art date
Application number
FI833417A
Other languages
English (en)
Other versions
FI78094B (fi
FI833417A (fi
FI78094C (fi
Inventor
Choung Un Kim
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI833417A0 publication Critical patent/FI833417A0/fi
Publication of FI833417A publication Critical patent/FI833417A/fi
Publication of FI78094B publication Critical patent/FI78094B/fi
Application granted granted Critical
Publication of FI78094C publication Critical patent/FI78094C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/64Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with substituted hydrocarbon radicals attached to ring carbon atoms, e.g. histidine
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/28Radicals substituted by singly-bound oxygen or sulphur atoms
    • C07D213/32Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/041,2,3-Triazoles; Hydrogenated 1,2,3-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D249/00Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms
    • C07D249/02Heterocyclic compounds containing five-membered rings having three nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D249/081,2,4-Triazoles; Hydrogenated 1,2,4-triazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D257/00Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms
    • C07D257/02Heterocyclic compounds containing rings having four nitrogen atoms as the only ring hetero atoms not condensed with other rings
    • C07D257/04Five-membered rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D277/00Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings
    • C07D277/02Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings
    • C07D277/20Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members
    • C07D277/22Heterocyclic compounds containing 1,3-thiazole or hydrogenated 1,3-thiazole rings not condensed with other rings having two or three double bonds between ring members or between ring members and non-ring members with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to ring carbon atoms
    • C07D277/26Radicals substituted by sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/061,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D477/00Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring
    • C07D477/10Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2
    • C07D477/12Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6
    • C07D477/16Heterocyclic compounds containing 1-azabicyclo [3.2.0] heptane ring systems, i.e. compounds containing a ring system of the formula:, e.g. carbapenicillins, thienamycins; Such ring systems being further condensed, e.g. 2,3-condensed with an oxygen-, nitrogen- or sulphur-containing hetero ring with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached in position 4, and with a carbon atom having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 2 with hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, attached in position 6 with hetero atoms or carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. an ester or nitrile radical, directly attached in position 3
    • C07D477/20Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F7/00Compounds containing elements of Groups 4 or 14 of the Periodic Table
    • C07F7/02Silicon compounds
    • C07F7/08Compounds having one or more C—Si linkages
    • C07F7/18Compounds having one or more C—Si linkages as well as one or more C—O—Si linkages
    • C07F7/1804Compounds having Si-O-C linkages
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07FACYCLIC, CARBOCYCLIC OR HETEROCYCLIC COMPOUNDS CONTAINING ELEMENTS OTHER THAN CARBON, HYDROGEN, HALOGEN, OXYGEN, NITROGEN, SULFUR, SELENIUM OR TELLURIUM
    • C07F9/00Compounds containing elements of Groups 5 or 15 of the Periodic Table
    • C07F9/02Phosphorus compounds
    • C07F9/547Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom
    • C07F9/6561Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings
    • C07F9/65611Heterocyclic compounds, e.g. containing phosphorus as a ring hetero atom containing systems of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring or ring system, with or without other non-condensed hetero rings containing the ring system (X = CH2, O, S, NH) optionally with an additional double bond and/or substituents, e.g. penicillins and analogs

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Biochemistry (AREA)
  • General Health & Medical Sciences (AREA)
  • Molecular Biology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Cephalosporin Compounds (AREA)
FI833417A 1982-09-28 1983-09-23 Foerfarande foer framstaellning av antibiotiskt aktiva karbapenemfoereningar. FI78094C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US42575582A 1982-09-28 1982-09-28
US42575582 1982-09-28
US53001183A 1983-09-09 1983-09-09
US53001183 1983-09-09

Publications (4)

Publication Number Publication Date
FI833417A0 true FI833417A0 (fi) 1983-09-23
FI833417A FI833417A (fi) 1984-03-29
FI78094B FI78094B (fi) 1989-02-28
FI78094C FI78094C (fi) 1989-06-12

Family

ID=27026797

Family Applications (1)

Application Number Title Priority Date Filing Date
FI833417A FI78094C (fi) 1982-09-28 1983-09-23 Foerfarande foer framstaellning av antibiotiskt aktiva karbapenemfoereningar.

Country Status (29)

Country Link
KR (1) KR890002228B1 (fi)
AR (1) AR241785A1 (fi)
AT (1) AT382621B (fi)
AU (1) AU575541B2 (fi)
CA (1) CA1269978A (fi)
CH (1) CH656130A5 (fi)
CS (1) CS247168B2 (fi)
DD (1) DD212255A5 (fi)
DE (1) DE3334937A1 (fi)
DK (1) DK442383A (fi)
ES (1) ES525983A0 (fi)
FI (1) FI78094C (fi)
FR (1) FR2533568B1 (fi)
GB (1) GB2128187B (fi)
GR (1) GR78696B (fi)
HU (1) HU191066B (fi)
IE (1) IE55947B1 (fi)
IL (1) IL69824A (fi)
IT (1) IT1163944B (fi)
LU (1) LU85021A1 (fi)
NL (1) NL8303310A (fi)
NO (1) NO163284C (fi)
NZ (1) NZ205626A (fi)
OA (1) OA07548A (fi)
PT (1) PT77404B (fi)
SE (1) SE461734B (fi)
SU (1) SU1493108A3 (fi)
YU (1) YU43196B (fi)
ZW (1) ZW20783A1 (fi)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4683296A (en) * 1983-03-07 1987-07-28 Bristol-Myers Company Carbapenem intermediates
CA1273011A (en) * 1984-07-02 1990-08-21 Susan M. Schmitt Carbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkylthio substituent
CA1273012A (en) * 1984-07-02 1990-08-21 Burton G. Christensen 1-methylcarbapenems having an externally alkylated mono- of bicyclic 2-quarternary heteroarylalkylthio substituent
US4725594A (en) * 1984-12-13 1988-02-16 Merck & Co., Inc. Carbapenems having an internally or externally alkylated mono- or bicyclic 2-quaternary heteroarylalxyl heteromethyl substituent
US4729993A (en) * 1984-12-13 1988-03-08 Merck & Co., Inc. Carbapenems and 1-methylcarbapenems having an externally alkylated mono- or bicyclic 2-quaternary heteroarylalkyl substituent
US4680292A (en) * 1984-12-13 1987-07-14 Merck & Co., Inc. Carbapenems and 1-methylcarbapenems having a 2-heteroaryliumaliphatic substituent
US4665169A (en) * 1985-09-11 1987-05-12 Bristol-Myers Company Carbapenem antibiotics
US4880922A (en) * 1985-11-22 1989-11-14 Bristol-Myers Company Carbapenems with quaternized heterothioalkylthio substitution at position 2
NZ219892A (en) * 1986-04-15 1991-02-26 Merck & Co Inc N-amino quaternised heteroarylium carbapenem derivatives and pharmaceutical compositions thereof
DK168047B1 (da) * 1987-12-07 1994-01-24 Lederle Japan Ltd (1r,5s,6s)-2-substitueret thio-6-oe(r)-1-hydroxyethylaa-1-methyl-carbapenem-3-carboxylsyrederivater, fremgangsmaade til remstilling deraf, midler og praeparater indeholdende den krystallinske forbindelse samt dens anvendelse.
US6174877B1 (en) 1996-01-12 2001-01-16 Takeda Chemical Industries, Ltd. Carbapenem compound, their production and use

Family Cites Families (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
EP0017992A1 (en) * 1979-04-19 1980-10-29 Merck & Co. Inc. 2-Substituted-6-substituted-1-carbadethiapen-2-em-3-carboxylic acids, processes for preparing them, antibiotic pharmaceutical compositions containing same and process for preparing intermediates
IE52147B1 (en) * 1980-03-27 1987-07-08 Merck & Co Inc 4-(3-carboxy-2-oxopropyl)-azetidin-2-ones and process for their preparation
EP0038869A1 (en) * 1980-04-30 1981-11-04 Merck & Co. Inc. Process for the preparation of 1-carbapenems, and intermediates for their preparation
PT73791B (en) * 1980-10-17 1983-10-14 Merck & Co Inc Process for preparing 2-carbamimidoyl-6-substituted-1- -carbadethiapen-2-em-3-carboxylic acids
EP0050927B1 (en) * 1980-10-25 1985-03-27 Beecham Group Plc The preparation of beta-lactam antibiotics
US4552873A (en) * 1981-08-19 1985-11-12 Sankyo Company Limited Carbapenem compounds, and compositions containing them
EP0074599A1 (en) * 1981-09-09 1983-03-23 Takeda Chemical Industries, Ltd. 5,6-cis-Carbapenem derivatives, their production and use

Also Published As

Publication number Publication date
FR2533568B1 (fr) 1990-01-26
OA07548A (fr) 1985-03-31
GB2128187A (en) 1984-04-26
KR890002228B1 (ko) 1989-06-24
FI78094B (fi) 1989-02-28
CS247168B2 (en) 1986-12-18
ZW20783A1 (en) 1984-11-28
AU575541B2 (en) 1988-08-04
SE8305217L (sv) 1984-03-29
HU191066B (en) 1987-01-28
AU1934283A (en) 1984-04-05
PT77404B (en) 1986-06-26
GR78696B (fi) 1984-09-27
DE3334937C2 (fi) 1991-05-02
SE8305217D0 (sv) 1983-09-27
AT382621B (de) 1987-03-25
SU1493108A3 (ru) 1989-07-07
IL69824A (en) 1991-04-15
DK442383D0 (da) 1983-09-27
NO163284C (no) 1990-05-02
ES8503354A1 (es) 1985-02-16
KR840006249A (ko) 1984-11-22
YU190683A (en) 1985-10-31
DK442383A (da) 1984-03-29
SE461734B (sv) 1990-03-19
FI833417A (fi) 1984-03-29
IT1163944B (it) 1987-04-08
GB2128187B (en) 1986-06-18
NO163284B (no) 1990-01-22
DE3334937A1 (de) 1984-04-05
LU85021A1 (fr) 1984-04-24
ES525983A0 (es) 1985-02-16
IE55947B1 (en) 1991-02-27
NL8303310A (nl) 1984-04-16
DD212255A5 (de) 1984-08-08
IT8323022A0 (it) 1983-09-27
IL69824A0 (en) 1983-12-30
PT77404A (en) 1983-10-01
YU43196B (en) 1989-04-30
FI78094C (fi) 1989-06-12
CH656130A5 (de) 1986-06-13
GB8325744D0 (en) 1983-10-26
NO833479L (no) 1984-03-29
CA1269978A (en) 1990-06-05
ATA344983A (de) 1986-08-15
AR241785A1 (es) 1992-12-30
IE832266L (en) 1984-03-28
FR2533568A1 (fr) 1984-03-30
NZ205626A (en) 1986-12-05

Similar Documents

Publication Publication Date Title
DK315083D0 (da) Mufferoerdel
FI830786A0 (fi) Hygienprodukter foer oralt bruk
BE895653A (fr) Katalytische verbrander
BR8304069A (pt) Pessario intra-ulterino
FI833417A (fi) Carbapenemantibiotika
BR8208084A (pt) Microcomutador
BE895921A (fr) Sterilet
BE894865A (fr) Biertransportwagen
AT373020B (de) Ruestungstraeger
AT381170B (de) Hypsometer
AT382452B (de) Drehrohrofen
AR226015A1 (es) Catre-reposera
AR225385A1 (es) Jeringa-ampolla
ATA280282A (de) Grasschi
BR8202644A (pt) Micro - irrigador
BR6201022U (pt) Fiteiro
IT8232826V0 (it) Serraportamuffole
BR6201181U (pt) Varal
ATA469782A (de) Pedalergometer
BR8204630A (pt) Emissor-conversor eletrootico
ATA13982A (de) Schistock
FI821848A0 (fi) Doerrmekanism
BR6201225U (pt) Unisola
BR8202738A (pt) Passalama
FI821700A0 (fi) Vaexellok

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BRISTOL-MYERS CO