FI78917C - Foerfarande foer framstaellning av terapeutiskt aktiva substituerade dipeptider. - Google Patents

Foerfarande foer framstaellning av terapeutiskt aktiva substituerade dipeptider. Download PDF

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Publication number
FI78917C
FI78917C FI834280A FI834280A FI78917C FI 78917 C FI78917 C FI 78917C FI 834280 A FI834280 A FI 834280A FI 834280 A FI834280 A FI 834280A FI 78917 C FI78917 C FI 78917C
Authority
FI
Finland
Prior art keywords
phenylethyl
alanine
phenylalanyl
dimethyl
carbonyl
Prior art date
Application number
FI834280A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI834280A0 (fi
FI78917B (fi
FI834280A (fi
Inventor
Joel Gilbert Berger
Original Assignee
Schering Corp
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Schering Corp filed Critical Schering Corp
Publication of FI834280A0 publication Critical patent/FI834280A0/fi
Publication of FI834280A publication Critical patent/FI834280A/fi
Application granted granted Critical
Publication of FI78917B publication Critical patent/FI78917B/fi
Publication of FI78917C publication Critical patent/FI78917C/fi

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Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/04Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing only normal peptide links
    • C07K5/06Dipeptides
    • C07K5/06008Dipeptides with the first amino acid being neutral
    • C07K5/06017Dipeptides with the first amino acid being neutral and aliphatic
    • C07K5/06034Dipeptides with the first amino acid being neutral and aliphatic the side chain containing 2 to 4 carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C51/00Preparation of carboxylic acids or their salts, halides or anhydrides
    • C07C51/347Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups
    • C07C51/373Preparation of carboxylic acids or their salts, halides or anhydrides by reactions not involving formation of carboxyl groups by introduction of functional groups containing oxygen only in doubly bound form
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C59/00Compounds having carboxyl groups bound to acyclic carbon atoms and containing any of the groups OH, O—metal, —CHO, keto, ether, groups, groups, or groups
    • C07C59/40Unsaturated compounds
    • C07C59/76Unsaturated compounds containing keto groups
    • C07C59/84Unsaturated compounds containing keto groups containing six membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D307/00Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom
    • C07D307/77Heterocyclic compounds containing five-membered rings having one oxygen atom as the only ring hetero atom ortho- or peri-condensed with carbocyclic rings or ring systems
    • C07D307/87Benzo [c] furans; Hydrogenated benzo [c] furans
    • C07D307/89Benzo [c] furans; Hydrogenated benzo [c] furans with two oxygen atoms directly attached in positions 1 and 3
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D317/00Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms
    • C07D317/08Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3
    • C07D317/10Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings
    • C07D317/14Heterocyclic compounds containing five-membered rings having two oxygen atoms as the only ring hetero atoms having the hetero atoms in positions 1 and 3 not condensed with other rings with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D317/18Radicals substituted by singly bound oxygen or sulfur atoms
    • C07D317/24Radicals substituted by singly bound oxygen or sulfur atoms esterified
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07KPEPTIDES
    • C07K5/00Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof
    • C07K5/02Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link
    • C07K5/022Peptides containing up to four amino acids in a fully defined sequence; Derivatives thereof containing at least one abnormal peptide link containing the structure -X-C(=O)-(C)n-N-C-C(=O)-Y-; X and Y being heteroatoms; n being 1 or 2
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61KPREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K38/00Medicinal preparations containing peptides

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Medicinal Chemistry (AREA)
  • Molecular Biology (AREA)
  • Biochemistry (AREA)
  • Biophysics (AREA)
  • General Health & Medical Sciences (AREA)
  • Genetics & Genomics (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Engineering & Computer Science (AREA)
  • Oil, Petroleum & Natural Gas (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
  • Peptides Or Proteins (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI834280A 1982-11-26 1983-11-23 Foerfarande foer framstaellning av terapeutiskt aktiva substituerade dipeptider. FI78917C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US44476182A 1982-11-26 1982-11-26
US44476182 1982-11-26
US48346383A 1983-04-11 1983-04-11
US48346383 1983-04-11

Publications (4)

Publication Number Publication Date
FI834280A0 FI834280A0 (fi) 1983-11-23
FI834280A FI834280A (fi) 1984-05-27
FI78917B FI78917B (fi) 1989-06-30
FI78917C true FI78917C (fi) 1989-10-10

Family

ID=27034046

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834280A FI78917C (fi) 1982-11-26 1983-11-23 Foerfarande foer framstaellning av terapeutiskt aktiva substituerade dipeptider.

Country Status (11)

Country Link
KR (1) KR910002549B1 (ko)
AU (1) AU565481B2 (ko)
CA (1) CA1250091A (ko)
DK (1) DK533483A (ko)
FI (1) FI78917C (ko)
HU (1) HU193887B (ko)
IL (1) IL70309A (ko)
NO (1) NO169172C (ko)
NZ (1) NZ206362A (ko)
OA (1) OA07594A (ko)
PT (1) PT77699B (ko)

Also Published As

Publication number Publication date
NO169172B (no) 1992-02-10
HU193887B (en) 1987-12-28
AU565481B2 (en) 1987-09-17
FI834280A0 (fi) 1983-11-23
NZ206362A (en) 1988-11-29
OA07594A (fr) 1985-03-31
KR840007568A (ko) 1984-12-08
PT77699A (en) 1983-12-01
PT77699B (en) 1986-05-12
FI78917B (fi) 1989-06-30
CA1250091A (en) 1989-02-14
NO834294L (no) 1984-05-28
DK533483D0 (da) 1983-11-22
NO169172C (no) 1992-05-27
IL70309A (en) 1988-11-30
AU2157783A (en) 1984-05-31
FI834280A (fi) 1984-05-27
KR910002549B1 (ko) 1991-04-24
DK533483A (da) 1984-05-27
IL70309A0 (en) 1984-02-29

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: SCHERING CORPORATION