FI78701C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara mitocanderivat. - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara mitocanderivat. Download PDF

Info

Publication number
FI78701C
FI78701C FI841380A FI841380A FI78701C FI 78701 C FI78701 C FI 78701C FI 841380 A FI841380 A FI 841380A FI 841380 A FI841380 A FI 841380A FI 78701 C FI78701 C FI 78701C
Authority
FI
Finland
Prior art keywords
mitomycin
formula
compound
preparation
dose
Prior art date
Application number
FI841380A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI78701B (fi
FI841380A7 (fi
FI841380A0 (fi
Inventor
Terrence William Doyle
Yulin Chiang
Dolatrai Mohanlal Vyas
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI841380A0 publication Critical patent/FI841380A0/fi
Publication of FI841380A7 publication Critical patent/FI841380A7/fi
Application granted granted Critical
Publication of FI78701B publication Critical patent/FI78701B/fi
Publication of FI78701C publication Critical patent/FI78701C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/12—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains three hetero rings
    • C07D487/14—Ortho-condensed systems

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Medicines That Contain Protein Lipid Enzymes And Other Medicines (AREA)
FI841380A 1983-04-11 1984-04-06 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara mitocanderivat. FI78701C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US48401683A 1983-04-11 1983-04-11
US48401683 1983-04-11
US58129184 1984-02-24
US06/581,291 US4803212A (en) 1983-04-11 1984-02-24 Amino disulfides

Publications (4)

Publication Number Publication Date
FI841380A0 FI841380A0 (fi) 1984-04-06
FI841380A7 FI841380A7 (fi) 1984-10-12
FI78701B FI78701B (fi) 1989-05-31
FI78701C true FI78701C (fi) 1989-09-11

Family

ID=27047825

Family Applications (1)

Application Number Title Priority Date Filing Date
FI841380A FI78701C (fi) 1983-04-11 1984-04-06 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara mitocanderivat.

Country Status (23)

Country Link
US (1) US4803212A (enExample)
KR (1) KR890001488B1 (enExample)
AT (1) AT387019B (enExample)
AU (1) AU577523B2 (enExample)
CA (1) CA1285567C (enExample)
CH (1) CH661273A5 (enExample)
CY (1) CY1533A (enExample)
DE (1) DE3413489A1 (enExample)
DK (1) DK170071B1 (enExample)
ES (1) ES531338A0 (enExample)
FI (1) FI78701C (enExample)
FR (1) FR2543953B1 (enExample)
GB (1) GB2140799B (enExample)
GR (1) GR79579B (enExample)
HK (1) HK82690A (enExample)
IE (1) IE57348B1 (enExample)
IT (1) IT1176003B (enExample)
LU (1) LU85295A1 (enExample)
MX (1) MX9202850A (enExample)
MY (1) MY102071A (enExample)
NL (1) NL8401104A (enExample)
PT (1) PT78399B (enExample)
SE (1) SE461735B (enExample)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
US4866180A (en) * 1984-02-24 1989-09-12 Bristol-Myers Company Amino disulfide thiol exchange products
JPS60255789A (ja) * 1984-06-01 1985-12-17 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体，その製造法および抗腫瘍剤
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes
US4927943A (en) * 1984-09-04 1990-05-22 Bristol-Myers Company Substituted 7-oxomitosanes
US4888341A (en) * 1984-09-04 1989-12-19 University Patents, Inc. 6-substituted mitomycin analogs
DE3674043D1 (de) * 1985-04-10 1990-10-18 Kyowa Hakko Kogyo Kk Pharmakologisch aktive mitomycinderivate.
JPS6354380A (ja) * 1986-08-26 1988-03-08 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
JPS63150282A (ja) * 1986-12-13 1988-06-22 Kyowa Hakko Kogyo Co Ltd マイトマイシン誘導体
ZA886812B (en) * 1987-11-23 1989-07-26 Bristol Myers Co Anti-tumor prodrugs
US5075454A (en) * 1990-03-08 1991-12-24 Bristol-Myers Squibb Company 7-(diphenylmethyl)oxy-9a-methoxymitosane
US5175303A (en) * 1990-03-08 1992-12-29 Bristol-Myers Squibb Company Preparation of 7-(diphenylmethyl)oxy-9A-methoxymitosane

Family Cites Families (13)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3660578A (en) * 1957-04-06 1972-05-02 Kyowa Hakko Kogyo Kk Mitomycin c
NL129868C (enExample) * 1963-06-07
DE1570029A1 (de) * 1964-07-09 1970-04-09 Kyowa Hakko Kogyo Kk Verfahren zur Herstellung von Mitosanverbindungen
NL130086C (enExample) * 1964-07-14 1970-06-15
US3332944A (en) * 1964-11-02 1967-07-25 American Cyanamid Co Antibiotic derivatives of mitomycins a, b, c and porfiromycin
JPS5439098A (en) * 1977-08-31 1979-03-24 Kyowa Hakko Kogyo Co Ltd Mitomycin c derivatives
US4268676A (en) * 1979-12-05 1981-05-19 University Patents, Inc. Mitomycin analogs
GB2093643A (en) * 1981-02-17 1982-09-02 Standard Telephones Cables Ltd DC-to-DC converter
NZ199617A (en) * 1981-05-15 1985-08-30 University Patents Inc Azirino(2',3',:3,4)pyrrolo(1,2-a)indole-4,7-dione derivatives and pharmaceutical compositions
US4487769A (en) * 1982-06-04 1984-12-11 Bristol-Myers Company Amidines
EP0116208B1 (en) * 1982-12-07 1988-03-30 Kyowa Hakko Kogyo Co., Ltd. Mitomycin analogues
US4642352A (en) * 1983-12-23 1987-02-10 Bristol-Myers Company Acylamino mitosanes
AU581673B2 (en) * 1984-09-04 1989-03-02 Bristol-Myers Company Substituted 7-oxomitosanes

Also Published As

Publication number Publication date
SE8401999L (sv) 1984-10-12
CH661273A5 (de) 1987-07-15
FR2543953A1 (fr) 1984-10-12
IE57348B1 (en) 1992-08-12
ES8602798A1 (es) 1985-12-01
LU85295A1 (fr) 1984-11-28
DK170071B1 (da) 1995-05-15
FI78701B (fi) 1989-05-31
KR890001488B1 (ko) 1989-05-04
AU2595184A (en) 1984-10-18
DK183984A (da) 1984-10-12
PT78399B (en) 1986-07-17
CY1533A (en) 1990-11-16
GB2140799B (en) 1987-04-08
GB8409242D0 (en) 1984-05-23
FR2543953B1 (fr) 1988-08-26
AT387019B (de) 1988-11-25
DE3413489C2 (enExample) 1991-07-25
AU577523B2 (en) 1988-09-29
DK183984D0 (da) 1984-04-09
DE3413489A1 (de) 1984-10-11
IT1176003B (it) 1987-08-12
NL8401104A (nl) 1984-11-01
MX9202850A (es) 1992-06-30
FI841380A7 (fi) 1984-10-12
GB2140799A (en) 1984-12-05
FI841380A0 (fi) 1984-04-06
IT8420478A0 (it) 1984-04-10
GR79579B (enExample) 1984-10-30
HK82690A (en) 1990-10-19
MY102071A (en) 1992-03-31
PT78399A (en) 1984-05-01
IE840878L (en) 1984-10-11
ES531338A0 (es) 1985-12-01
ATA122384A (de) 1988-04-15
IT8420478A1 (it) 1985-10-10
CA1285567C (en) 1991-07-02
US4803212A (en) 1989-02-07
SE461735B (sv) 1990-03-19
SE8401999D0 (sv) 1984-04-10

Similar Documents

Publication Publication Date Title
FI78701B (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara mitocanderivat.
CN117500792A (zh) 用于抑制nlrp3的哒嗪化合物
Webb et al. The Structures of Mitomycins A, B and C and Porfiromycin--Part I
EP2895488B1 (en) Tricyclic gyrase inhibitors for use as antibacterial agents
KR0137959B1 (ko) 2개의 cpi 소단위를 갖는 신규한 cc-1065 유사화합물
AU2006316071A1 (en) Oxygen linked pyrimidine derivatives
EP2686320A1 (en) Tricyclic gyrase inhibitors
WO2013093615A1 (en) Tricyclic boron compounds for antimicrobial therapy
KR870000932B1 (ko) 아미딘류의 제조 방법
AU2021398802A1 (en) Compound and preparation method thereof and application thereof in preparation of therapeutic anti-cancer drug
US4866180A (en) Amino disulfide thiol exchange products
WO2015016558A1 (ko) 트리사이클릭 벤즈옥사보롤 화합물, 이의 제조방법 및 용도
WO2023193790A1 (en) Crystalline forms of an inhibitor of the menin/mll interaction
CN116323571A (zh) 肌酸激酶（ck）的共价抑制剂以及其用于治疗和预防癌症的用途
EP0324109B1 (en) 6-substituted mitomycin analogs
FI82941C (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara titanocenkomplex.
FI81099B (fi) Foerfarande foer framstaellning av terapeutiskt aktiva mitomycinanaloger.
WO2019122438A1 (en) New antibiotics targeting mycobacteria
GB2106096A (en) Mitomycin derivatives their preparation and use
CN114746428B (zh) Mcl1抑制剂及其应用
Wu et al. Intramolecularity and the function of the side arm base of simple models of transaminases
KR20200017411A (ko) 괴사 억제제로서 헤테로아릴 화합물, 이의 조성물 및 이의 이용 방법
WO2021083438A1 (en) Inhibitors of purine nucleoside phosphorylase - synthesis and use thereof for treatment of t-cell acute lymphoblastic leukemia and lymphoma
Brukštus et al. Synthesis of novel pyrimido [5, 4-f][1, 2, 4] triazolo [3, 4-b][1, 3, 4] thiadiazepines
IE892691L (en) Mitomycin derivatives

Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: BRISTOL-MYERS CO