FI77840B - Foerfarande foer framstaellning av terapeutiskt anvaendbara resorcinderivat. - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara resorcinderivat. Download PDF

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Publication number
FI77840B
FI77840B FI834797A FI834797A FI77840B FI 77840 B FI77840 B FI 77840B FI 834797 A FI834797 A FI 834797A FI 834797 A FI834797 A FI 834797A FI 77840 B FI77840 B FI 77840B
Authority
FI
Finland
Prior art keywords
formula
compounds
ethanol
animals
carbon atoms
Prior art date
Application number
FI834797A
Other languages
English (en)
Finnish (fi)
Other versions
FI77840C (sv
FI834797A (fi
FI834797A0 (fi
Inventor
Edit Toth
Jozsef Toerley
Laszlo Szporny
Sandor Goeroeg
Istvan Hajdu
Eva Palosi
Gyoergy Fekete
Laszlo Vereczkey
Imre Klebovich
Pal Vittay
Original Assignee
Richter Gedeon Vegyeszet
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszet filed Critical Richter Gedeon Vegyeszet
Publication of FI834797A0 publication Critical patent/FI834797A0/fi
Publication of FI834797A publication Critical patent/FI834797A/fi
Application granted granted Critical
Publication of FI77840B publication Critical patent/FI77840B/fi
Publication of FI77840C publication Critical patent/FI77840C/sv

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/11—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
    • C07C37/20—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms using aldehydes or ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups

Claims (2)

1. Förfarande för framställning av terapeutiskt användbara resorcinderivat med formeln (I), R, OH
1 CxH5 väri Rl betyder väte eller en alkyl med 1 - 3 kolatomer ooh R2 betyder halogen, en alkyl med 1 - 3 kolatomer, en alkoxi med 1 - 3 kolatomer eller en trifluormetyl-grupp, kännetecknad därav, att a) man omsätter 2',4'-dihydroxipropiofenon med en Grignard-förening med formeln (II), Γ j^V-MgX (II> Rl=/ väri Ri och R2 har samma innebörd som ovan och X är halogen, eller b) man omsätter 2',4'-dihydroksipropiofenon med en metall-organisk förening med formeln (III),
FI834797A 1982-12-28 1983-12-27 Förfarande för framställning av terapeutiskt användbara resorcinderiva t. FI77840C (sv)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
HU418982 1982-12-28
HU824189A HU188239B (en) 1982-12-28 1982-12-28 Process for the production of new resorcinol-derivatives and of therapeutic preparations containing them

Publications (4)

Publication Number Publication Date
FI834797A0 FI834797A0 (fi) 1983-12-27
FI834797A FI834797A (fi) 1984-06-29
FI77840B true FI77840B (fi) 1989-01-31
FI77840C FI77840C (sv) 1989-05-10

Family

ID=10967263

Family Applications (1)

Application Number Title Priority Date Filing Date
FI834797A FI77840C (sv) 1982-12-28 1983-12-27 Förfarande för framställning av terapeutiskt användbara resorcinderiva t.

Country Status (14)

Country Link
US (1) US4510338A (sv)
EP (1) EP0112587B1 (sv)
JP (1) JPS59134741A (sv)
AT (1) ATE56696T1 (sv)
AU (1) AU558203B2 (sv)
CA (1) CA1198741A (sv)
DE (1) DE3381892D1 (sv)
DK (1) DK159769C (sv)
ES (2) ES8604083A1 (sv)
FI (1) FI77840C (sv)
GR (1) GR79147B (sv)
HU (1) HU188239B (sv)
IL (1) IL70557A (sv)
ZA (1) ZA839617B (sv)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK293888A (da) * 1987-06-09 1988-12-10 Takeda Chemical Industries Ltd Fenolderivater og deres fremstilling og anvendelse
KR100270410B1 (ko) * 1997-03-06 2000-11-01 성재갑 타이로시네이즈 활성 저해능을 갖는 신규 1,3-디페닐프로판 유도체 및 그의 제조방법
KR19990069212A (ko) * 1998-02-05 1999-09-06 성재갑 타이로시나제 저해활성을 갖는 신규 폴리하이드록시-디페닐메탄유도체 및 그의 제조방법
US7233316B2 (en) 2003-05-01 2007-06-19 Thomson Licensing Multimedia user interface
WO2023106973A1 (ru) * 2021-12-10 2023-06-15 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новые гепатопротекторные средства

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2247404A (en) * 1939-03-24 1941-07-01 Dow Chemical Co Aralkyl polyhydric phenol
US2719866A (en) * 1951-08-04 1955-10-04 Lilly Co Eli Substituted resorcinols
FR2121446B1 (sv) * 1971-01-14 1974-03-22 Pechiney Ugine Kuhlmann
DE2260138A1 (de) * 1972-12-08 1974-06-12 Hoechst Ag Stoffwechselwirksame bisphenolalkanderivate
US4094908A (en) * 1973-08-15 1978-06-13 Richter Gedeon Vegyeszeti Gyar Rt. Alpha-substituted benzhydrol derivatives

Also Published As

Publication number Publication date
IL70557A (en) 1987-11-30
ATE56696T1 (de) 1990-10-15
CA1198741A (en) 1985-12-31
FI77840C (sv) 1989-05-10
AU2291283A (en) 1984-07-05
GR79147B (sv) 1984-10-02
FI834797A (fi) 1984-06-29
ES528459A0 (es) 1986-01-16
EP0112587A2 (de) 1984-07-04
HUT34945A (en) 1985-05-28
DK601783D0 (da) 1983-12-27
ES8604083A1 (es) 1986-01-16
JPS59134741A (ja) 1984-08-02
HU188239B (en) 1986-03-28
AU558203B2 (en) 1987-01-22
ES8603802A1 (es) 1986-01-01
DE3381892D1 (de) 1990-10-25
ES543799A0 (es) 1986-01-01
DK601783A (da) 1984-06-29
DK159769B (da) 1990-12-03
ZA839617B (en) 1984-08-29
EP0112587B1 (de) 1990-09-19
EP0112587A3 (en) 1986-03-12
JPH0237900B2 (sv) 1990-08-28
DK159769C (da) 1991-04-22
FI834797A0 (fi) 1983-12-27
US4510338A (en) 1985-04-09
IL70557A0 (en) 1984-03-30

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Legal Events

Date Code Title Description
MM Patent lapsed
MM Patent lapsed

Owner name: RICHTER GEDEON VEGYESZETI GYAR R.T.