ES8604083A1 - Procedimiento de preparacion de nuevos derivados 1-hidroxipropil resorcinos provistos de un grupo fenilo sustituidos. - Google Patents

Procedimiento de preparacion de nuevos derivados 1-hidroxipropil resorcinos provistos de un grupo fenilo sustituidos.

Info

Publication number
ES8604083A1
ES8604083A1 ES528459A ES528459A ES8604083A1 ES 8604083 A1 ES8604083 A1 ES 8604083A1 ES 528459 A ES528459 A ES 528459A ES 528459 A ES528459 A ES 528459A ES 8604083 A1 ES8604083 A1 ES 8604083A1
Authority
ES
Spain
Prior art keywords
pref
formula
phenyl
trifluoromethyl
resorcinol
Prior art date
Legal status (The legal status is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the status listed.)
Expired
Application number
ES528459A
Other languages
English (en)
Other versions
ES528459A0 (es
Current Assignee (The listed assignees may be inaccurate. Google has not performed a legal analysis and makes no representation or warranty as to the accuracy of the list.)
Richter Gedeon Vegyeszeti Gyar Nyrt
Original Assignee
Richter Gedeon Vegyeszeti Gyar RT
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Richter Gedeon Vegyeszeti Gyar RT filed Critical Richter Gedeon Vegyeszeti Gyar RT
Publication of ES8604083A1 publication Critical patent/ES8604083A1/es
Publication of ES528459A0 publication Critical patent/ES528459A0/es
Expired legal-status Critical Current

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/12—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring polycyclic with no unsaturation outside the aromatic rings
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/30—Drugs for disorders of the nervous system for treating abuse or dependence
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C37/00—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring
    • C07C37/11—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms
    • C07C37/20—Preparation of compounds having hydroxy or O-metal groups bound to a carbon atom of a six-membered aromatic ring by reactions increasing the number of carbon atoms using aldehydes or ketones
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C39/00—Compounds having at least one hydroxy or O-metal group bound to a carbon atom of a six-membered aromatic ring
    • C07C39/24—Halogenated derivatives
    • C07C39/367—Halogenated derivatives polycyclic non-condensed, containing only six-membered aromatic rings as cyclic parts, e.g. halogenated poly-hydroxyphenylalkanes
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C41/00—Preparation of ethers; Preparation of compounds having groups, groups or groups
    • C07C41/01—Preparation of ethers
    • C07C41/18—Preparation of ethers by reactions not forming ether-oxygen bonds
    • C07C41/30—Preparation of ethers by reactions not forming ether-oxygen bonds by increasing the number of carbon atoms, e.g. by oligomerisation
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C43/00—Ethers; Compounds having groups, groups or groups
    • C07C43/02—Ethers
    • C07C43/20—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring
    • C07C43/23—Ethers having an ether-oxygen atom bound to a carbon atom of a six-membered aromatic ring containing hydroxy or O-metal groups

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Engineering & Computer Science (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Psychiatry (AREA)
  • Addiction (AREA)
  • Biomedical Technology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
  • Diaphragms For Electromechanical Transducers (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Hydrogenated Pyridines (AREA)

Abstract

PROCEDIMIENTO PARA LA OBTENCION DE DERIVADOS 1-HIDROXIPROPILRESORCINOS, DE FORMULA (I), EN LA QUE R1 Y R2 PUEDEN SER VARIOS TIPOS DE RADICALES. CONSISTE EN LA REACCION DE 2,4-DIHIDROXI-PROPIOFENONA CON UN COMPUESTO DE FORMULA (I) EN LA QUE R1 Y R2 TIENEN EL MISMO SIGNIFICADO QUE EN LA FORMULA (I) Y M ES UN METAL ALCALINO O UN GRUPO MGX, DONDE X ES UN ATOMO DE HALOGENO. LA REACCION SE LLEVA A CABO EN UN DISOLVENTE ORGANICO APROTICO, ANHIDRO, A UNA TEMPERATURA COMPRENDIDA ENTRE C30JC Y LA DE EBULLICION DEL DISOLVENTE. ESTOS COMPUESTOS TIENEN APLICACIONES FARMACOLOGICAS PARA EL TRATAMIENTO DE INTOXICACION ETANOLICA AGUDA.
ES528459A 1982-12-28 1983-12-27 Procedimiento de preparacion de nuevos derivados 1-hidroxipropil resorcinos provistos de un grupo fenilo sustituidos. Expired ES8604083A1 (es)

Applications Claiming Priority (1)

Application Number Priority Date Filing Date Title
HU824189A HU188239B (en) 1982-12-28 1982-12-28 Process for the production of new resorcinol-derivatives and of therapeutic preparations containing them

Publications (2)

Publication Number Publication Date
ES8604083A1 true ES8604083A1 (es) 1986-01-16
ES528459A0 ES528459A0 (es) 1986-01-16

Family

ID=10967263

Family Applications (2)

Application Number Title Priority Date Filing Date
ES528459A Expired ES8604083A1 (es) 1982-12-28 1983-12-27 Procedimiento de preparacion de nuevos derivados 1-hidroxipropil resorcinos provistos de un grupo fenilo sustituidos.
ES543799A Granted ES543799A0 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de nuevos derivados 1-hidroxi- propilresorcinos provistos de un grupo fenilo sustituido

Family Applications After (1)

Application Number Title Priority Date Filing Date
ES543799A Granted ES543799A0 (es) 1982-12-28 1985-06-01 Procedimiento de preparacion de nuevos derivados 1-hidroxi- propilresorcinos provistos de un grupo fenilo sustituido

Country Status (14)

Country Link
US (1) US4510338A (es)
EP (1) EP0112587B1 (es)
JP (1) JPS59134741A (es)
AT (1) ATE56696T1 (es)
AU (1) AU558203B2 (es)
CA (1) CA1198741A (es)
DE (1) DE3381892D1 (es)
DK (1) DK159769C (es)
ES (2) ES8604083A1 (es)
FI (1) FI77840C (es)
GR (1) GR79147B (es)
HU (1) HU188239B (es)
IL (1) IL70557A (es)
ZA (1) ZA839617B (es)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DK293888A (da) * 1987-06-09 1988-12-10 Takeda Chemical Industries Ltd Fenolderivater og deres fremstilling og anvendelse
KR100270410B1 (ko) * 1997-03-06 2000-11-01 성재갑 타이로시네이즈 활성 저해능을 갖는 신규 1,3-디페닐프로판 유도체 및 그의 제조방법
KR19990069212A (ko) * 1998-02-05 1999-09-06 성재갑 타이로시나제 저해활성을 갖는 신규 폴리하이드록시-디페닐메탄유도체 및 그의 제조방법
US7233316B2 (en) 2003-05-01 2007-06-19 Thomson Licensing Multimedia user interface
WO2023106973A1 (ru) * 2021-12-10 2023-06-15 Общество С Ограниченной Ответственностью "Валента-Интеллект" Новые гепатопротекторные средства

Family Cites Families (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2247404A (en) * 1939-03-24 1941-07-01 Dow Chemical Co Aralkyl polyhydric phenol
US2719866A (en) * 1951-08-04 1955-10-04 Lilly Co Eli Substituted resorcinols
FR2121446B1 (es) * 1971-01-14 1974-03-22 Pechiney Ugine Kuhlmann
DE2260138A1 (de) * 1972-12-08 1974-06-12 Hoechst Ag Stoffwechselwirksame bisphenolalkanderivate
US4094908A (en) * 1973-08-15 1978-06-13 Richter Gedeon Vegyeszeti Gyar Rt. Alpha-substituted benzhydrol derivatives

Also Published As

Publication number Publication date
FI834797A (fi) 1984-06-29
ATE56696T1 (de) 1990-10-15
JPH0237900B2 (es) 1990-08-28
FI77840C (fi) 1989-05-10
CA1198741A (en) 1985-12-31
FI834797A0 (fi) 1983-12-27
IL70557A (en) 1987-11-30
DE3381892D1 (de) 1990-10-25
AU2291283A (en) 1984-07-05
ES8603802A1 (es) 1986-01-01
ES543799A0 (es) 1986-01-01
US4510338A (en) 1985-04-09
DK601783D0 (da) 1983-12-27
EP0112587A2 (de) 1984-07-04
HU188239B (en) 1986-03-28
AU558203B2 (en) 1987-01-22
EP0112587B1 (de) 1990-09-19
IL70557A0 (en) 1984-03-30
ES528459A0 (es) 1986-01-16
EP0112587A3 (en) 1986-03-12
JPS59134741A (ja) 1984-08-02
ZA839617B (en) 1984-08-29
GR79147B (es) 1984-10-02
FI77840B (fi) 1989-01-31
DK159769B (da) 1990-12-03
DK159769C (da) 1991-04-22
HUT34945A (en) 1985-05-28
DK601783A (da) 1984-06-29

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Legal Events

Date Code Title Description
FD1A Patent lapsed

Effective date: 19970401