FI69462C - Foerfarande foer framstaellning av inflammationsmotverkande 4,-diaryl-2-(substituerad tio sulfinyl eller sulfonyl)imida zoderivat - Google Patents
Foerfarande foer framstaellning av inflammationsmotverkande 4,-diaryl-2-(substituerad tio sulfinyl eller sulfonyl)imida zoderivat Download PDFInfo
- Publication number
- FI69462C FI69462C FI780428A FI780428A FI69462C FI 69462 C FI69462 C FI 69462C FI 780428 A FI780428 A FI 780428A FI 780428 A FI780428 A FI 780428A FI 69462 C FI69462 C FI 69462C
- Authority
- FI
- Finland
- Prior art keywords
- thienyl
- imidazole
- mixture
- give
- pyridyl
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/22—Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
-
- A—HUMAN NECESSITIES
- A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
- A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
- A61P29/00—Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D213/00—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
- C07D213/02—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
- C07D213/04—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
- C07D213/24—Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
- C07D213/44—Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
- C07D213/46—Oxygen atoms
- C07D213/50—Ketonic radicals
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D233/00—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
- C07D233/54—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
- C07D233/66—Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
- C07D233/84—Sulfur atoms
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D333/00—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
- C07D333/02—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
- C07D333/04—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
- C07D333/06—Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
- C07D333/24—Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Health & Medical Sciences (AREA)
- Chemical Kinetics & Catalysis (AREA)
- Life Sciences & Earth Sciences (AREA)
- General Chemical & Material Sciences (AREA)
- Medicinal Chemistry (AREA)
- Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
- Pain & Pain Management (AREA)
- Pharmacology & Pharmacy (AREA)
- Rheumatology (AREA)
- Animal Behavior & Ethology (AREA)
- General Health & Medical Sciences (AREA)
- Public Health (AREA)
- Veterinary Medicine (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Plural Heterocyclic Compounds (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US76722077A | 1977-02-09 | 1977-02-09 | |
| US76722077 | 1977-02-09 | ||
| US86583278 | 1978-01-05 | ||
| US05/865,832 US4159338A (en) | 1977-02-09 | 1978-01-05 | Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI780428A7 FI780428A7 (fi) | 1978-08-10 |
| FI69462B FI69462B (fi) | 1985-10-31 |
| FI69462C true FI69462C (fi) | 1986-02-10 |
Family
ID=27117879
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI780428A FI69462C (fi) | 1977-02-09 | 1978-02-09 | Foerfarande foer framstaellning av inflammationsmotverkande 4,-diaryl-2-(substituerad tio sulfinyl eller sulfonyl)imida zoderivat |
Country Status (26)
| Country | Link |
|---|---|
| JP (1) | JPS53130664A (es) |
| AR (1) | AR219310A1 (es) |
| AT (1) | AT361470B (es) |
| AU (1) | AU517028B2 (es) |
| CA (1) | CA1105024A (es) |
| CH (1) | CH644108A5 (es) |
| DE (1) | DE2805167A1 (es) |
| DK (1) | DK16778A (es) |
| ES (1) | ES466794A1 (es) |
| FI (1) | FI69462C (es) |
| FR (1) | FR2380275A1 (es) |
| GB (1) | GB1564184A (es) |
| GR (1) | GR64142B (es) |
| HU (1) | HU178211B (es) |
| IE (1) | IE46187B1 (es) |
| IL (1) | IL53995A (es) |
| IT (1) | IT1092588B (es) |
| LU (1) | LU79024A1 (es) |
| MX (1) | MX5933E (es) |
| NL (1) | NL7801453A (es) |
| NO (1) | NO148265C (es) |
| NZ (1) | NZ186410A (es) |
| PH (1) | PH13852A (es) |
| PT (1) | PT67626B (es) |
| SE (1) | SE7801467L (es) |
| YU (1) | YU28878A (es) |
Families Citing this family (7)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0004648B1 (de) * | 1978-04-11 | 1982-08-25 | Ciba-Geigy Ag | Neue Mercaptoimidazolderivate, Verfahren zu deren Herstellung, Mercaptoimidazolderivate zur Behandlung entzündlicher Erkrankungen und diese enthaltende pharmazeutische Präparate |
| US4199592A (en) * | 1978-08-29 | 1980-04-22 | E. I. Du Pont De Nemours And Company | Antiinflammatory 4,5-diaryl-2-nitroimidazoles |
| DK337779A (da) * | 1978-10-02 | 1980-04-03 | Du Pont | Fremgangsmaade til fremstilling af antiinflammatoriske 2-substituerede 1h-phenantro (9,10)-imidazoler |
| AT374198B (de) * | 1979-04-10 | 1984-03-26 | Ciba Geigy Ag | Verfahren zur herstellung neuer 2-substituierter mercaptoimidazolderivate, ihrer n-oxyde und ihrer salze |
| FI850995L (fi) * | 1984-03-16 | 1985-09-17 | Ciba Geigy Ag | Foerfarande foer framstaellning av nya 3-merkapto-1,2,4-triazacykloalkadienderivat. |
| US6040320A (en) * | 1997-06-30 | 2000-03-21 | Ortho-Mcneil Pharmaceutical, Inc. | 2-substituted imidazoles useful in the treatment of inflammatory diseases |
| DE10107683A1 (de) | 2001-02-19 | 2002-08-29 | Merckle Gmbh Chem Pharm Fabrik | 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie |
Family Cites Families (4)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US2981739A (en) * | 1958-01-27 | 1961-04-25 | Diamond Alkali Co | Certain alpha-haloaldehyde addition products of ethylenethioureas and process |
| US3714179A (en) * | 1970-09-08 | 1973-01-30 | Searle & Co | 1-alkyl-2-furfurylthioimidazoles and congeners |
| JPS5343958B2 (es) * | 1972-07-29 | 1978-11-24 | ||
| SE428686B (sv) * | 1975-08-11 | 1983-07-18 | Du Pont | Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler |
-
1978
- 1978-01-13 DK DK16778A patent/DK16778A/da not_active Application Discontinuation
- 1978-02-06 PT PT67626A patent/PT67626B/pt unknown
- 1978-02-07 CA CA296,606A patent/CA1105024A/en not_active Expired
- 1978-02-07 IT IT7820078A patent/IT1092588B/it active
- 1978-02-08 LU LU79024A patent/LU79024A1/xx unknown
- 1978-02-08 NZ NZ186410A patent/NZ186410A/xx unknown
- 1978-02-08 IL IL53995A patent/IL53995A/xx unknown
- 1978-02-08 GB GB5098/78A patent/GB1564184A/en not_active Expired
- 1978-02-08 AU AU33096/78A patent/AU517028B2/en not_active Expired
- 1978-02-08 NL NL7801453A patent/NL7801453A/xx not_active Application Discontinuation
- 1978-02-08 SE SE7801467A patent/SE7801467L/xx unknown
- 1978-02-08 AT AT86978A patent/AT361470B/de not_active IP Right Cessation
- 1978-02-08 IE IE279/78A patent/IE46187B1/en unknown
- 1978-02-08 DE DE19782805167 patent/DE2805167A1/de not_active Withdrawn
- 1978-02-08 YU YU00288/78A patent/YU28878A/xx unknown
- 1978-02-08 MX MX786829U patent/MX5933E/es unknown
- 1978-02-08 NO NO780433A patent/NO148265C/no unknown
- 1978-02-08 FR FR7803518A patent/FR2380275A1/fr active Granted
- 1978-02-08 ES ES466794A patent/ES466794A1/es not_active Expired
- 1978-02-09 FI FI780428A patent/FI69462C/fi not_active IP Right Cessation
- 1978-02-09 GR GR55396A patent/GR64142B/el unknown
- 1978-02-09 PH PH20771A patent/PH13852A/en unknown
- 1978-02-09 JP JP1304678A patent/JPS53130664A/ja active Pending
- 1978-02-09 AR AR271048A patent/AR219310A1/es active
- 1978-02-09 CH CH147478A patent/CH644108A5/de not_active IP Right Cessation
- 1978-02-09 HU HU78DU279A patent/HU178211B/hu unknown
Also Published As
| Publication number | Publication date |
|---|---|
| NO148265B (no) | 1983-05-30 |
| AU3309678A (en) | 1979-08-16 |
| AR219310A1 (es) | 1980-08-15 |
| IT7820078A0 (it) | 1978-02-07 |
| YU28878A (en) | 1983-01-21 |
| FR2380275A1 (fr) | 1978-09-08 |
| DK16778A (da) | 1978-08-10 |
| NO148265C (no) | 1983-09-07 |
| GB1564184A (en) | 1980-04-02 |
| DE2805167A1 (de) | 1978-08-10 |
| IE780279L (en) | 1978-08-09 |
| AU517028B2 (en) | 1981-07-02 |
| MX5933E (es) | 1984-08-30 |
| AT361470B (de) | 1981-03-10 |
| PT67626A (en) | 1978-03-01 |
| PT67626B (en) | 1979-07-17 |
| CH644108A5 (en) | 1984-07-13 |
| NZ186410A (en) | 1979-12-11 |
| ES466794A1 (es) | 1979-08-01 |
| ATA86978A (de) | 1980-08-15 |
| JPS53130664A (en) | 1978-11-14 |
| FI780428A7 (fi) | 1978-08-10 |
| GR64142B (en) | 1980-01-28 |
| NO780433L (no) | 1978-08-10 |
| FI69462B (fi) | 1985-10-31 |
| FR2380275B1 (es) | 1982-01-08 |
| CA1105024A (en) | 1981-07-14 |
| PH13852A (en) | 1980-10-22 |
| HU178211B (en) | 1982-03-28 |
| SE7801467L (sv) | 1978-08-10 |
| IE46187B1 (en) | 1983-03-23 |
| IL53995A (en) | 1982-02-28 |
| NL7801453A (nl) | 1978-08-11 |
| IL53995A0 (en) | 1978-04-30 |
| LU79024A1 (fr) | 1979-05-25 |
| IT1092588B (it) | 1985-07-12 |
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Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: E.I. DU PONT DE NEMOURS AND CO |