NZ186410A - Imidazole derivatives and pharmaceutical compositions - Google Patents

Imidazole derivatives and pharmaceutical compositions

Info

Publication number
NZ186410A
NZ186410A NZ186410A NZ18641078A NZ186410A NZ 186410 A NZ186410 A NZ 186410A NZ 186410 A NZ186410 A NZ 186410A NZ 18641078 A NZ18641078 A NZ 18641078A NZ 186410 A NZ186410 A NZ 186410A
Authority
NZ
New Zealand
Prior art keywords
pharmaceutical compositions
imidazole derivatives
imidazole
derivatives
pharmaceutical
Prior art date
Application number
NZ186410A
Other languages
English (en)
Inventor
T Sharpe
S Cherkofsky
Original Assignee
Du Pont
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/865,832 external-priority patent/US4159338A/en
Application filed by Du Pont filed Critical Du Pont
Publication of NZ186410A publication Critical patent/NZ186410A/xx

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/22Radicals substituted by doubly bound hetero atoms, or by two hetero atoms other than halogen singly bound to the same carbon atom
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D213/00Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members
    • C07D213/02Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members
    • C07D213/04Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom
    • C07D213/24Heterocyclic compounds containing six-membered rings, not condensed with other rings, with one nitrogen atom as the only ring hetero atom and three or more double bonds between ring members or between ring members and non-ring members having three double bonds between ring members or between ring members and non-ring members having no bond between the ring nitrogen atom and a non-ring member or having only hydrogen or carbon atoms directly attached to the ring nitrogen atom with substituted hydrocarbon radicals attached to ring carbon atoms
    • C07D213/44Radicals substituted by doubly-bound oxygen, sulfur, or nitrogen atoms, or by two such atoms singly-bound to the same carbon atom
    • C07D213/46Oxygen atoms
    • C07D213/50Ketonic radicals
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D233/00Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings
    • C07D233/54Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members
    • C07D233/66Heterocyclic compounds containing 1,3-diazole or hydrogenated 1,3-diazole rings, not condensed with other rings having two double bonds between ring members or between ring members and non-ring members with hetero atoms or with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached to ring carbon atoms
    • C07D233/84Sulfur atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D333/00Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom
    • C07D333/02Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings
    • C07D333/04Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom
    • C07D333/06Heterocyclic compounds containing five-membered rings having one sulfur atom as the only ring hetero atom not condensed with other rings not substituted on the ring sulphur atom with only hydrogen atoms, hydrocarbon or substituted hydrocarbon radicals, directly attached to the ring carbon atoms
    • C07D333/24Radicals substituted by carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pain & Pain Management (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Rheumatology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Plural Heterocyclic Compounds (AREA)
NZ186410A 1977-02-09 1978-02-08 Imidazole derivatives and pharmaceutical compositions NZ186410A (en)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US76722077A 1977-02-09 1977-02-09
US05/865,832 US4159338A (en) 1977-02-09 1978-01-05 Antiinflammatory-4,5-dicyclic-2-(substituted thio)-imidazoles and their corresponding sulfoxides and sulfones

Publications (1)

Publication Number Publication Date
NZ186410A true NZ186410A (en) 1979-12-11

Family

ID=27117879

Family Applications (1)

Application Number Title Priority Date Filing Date
NZ186410A NZ186410A (en) 1977-02-09 1978-02-08 Imidazole derivatives and pharmaceutical compositions

Country Status (26)

Country Link
JP (1) JPS53130664A (xx)
AR (1) AR219310A1 (xx)
AT (1) AT361470B (xx)
AU (1) AU517028B2 (xx)
CA (1) CA1105024A (xx)
CH (1) CH644108A5 (xx)
DE (1) DE2805167A1 (xx)
DK (1) DK16778A (xx)
ES (1) ES466794A1 (xx)
FI (1) FI69462C (xx)
FR (1) FR2380275A1 (xx)
GB (1) GB1564184A (xx)
GR (1) GR64142B (xx)
HU (1) HU178211B (xx)
IE (1) IE46187B1 (xx)
IL (1) IL53995A (xx)
IT (1) IT1092588B (xx)
LU (1) LU79024A1 (xx)
MX (1) MX5933E (xx)
NL (1) NL7801453A (xx)
NO (1) NO148265C (xx)
NZ (1) NZ186410A (xx)
PH (1) PH13852A (xx)
PT (1) PT67626B (xx)
SE (1) SE7801467L (xx)
YU (1) YU28878A (xx)

Families Citing this family (7)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2963572D1 (en) * 1978-04-11 1982-10-21 Ciba Geigy Ag Mercapto-imidazole derivatives, their preparation, mercapto-imidazole derivatives for the treatment of inflammatory diseases and their pharmaceutical compositions
US4199592A (en) * 1978-08-29 1980-04-22 E. I. Du Pont De Nemours And Company Antiinflammatory 4,5-diaryl-2-nitroimidazoles
DK337779A (da) * 1978-10-02 1980-04-03 Du Pont Fremgangsmaade til fremstilling af antiinflammatoriske 2-substituerede 1h-phenantro (9,10)-imidazoler
AT374198B (de) * 1979-04-10 1984-03-26 Ciba Geigy Ag Verfahren zur herstellung neuer 2-substituierter mercaptoimidazolderivate, ihrer n-oxyde und ihrer salze
FI850995L (fi) * 1984-03-16 1985-09-17 Ciba Geigy Ag Foerfarande foer framstaellning av nya 3-merkapto-1,2,4-triazacykloalkadienderivat.
CA2295021A1 (en) * 1997-06-30 1999-01-28 Ortho-Mcneil Pharmaceutical, Inc. 2-substituted imidazoles useful in the treatment of inflammatory diseases
DE10107683A1 (de) 2001-02-19 2002-08-29 Merckle Gmbh Chem Pharm Fabrik 2-Thio-substituierte Imidazolderivate und ihre Verwendung in der Pharmazie

Family Cites Families (4)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2981739A (en) * 1958-01-27 1961-04-25 Diamond Alkali Co Certain alpha-haloaldehyde addition products of ethylenethioureas and process
US3714179A (en) * 1970-09-08 1973-01-30 Searle & Co 1-alkyl-2-furfurylthioimidazoles and congeners
JPS5343958B2 (xx) * 1972-07-29 1978-11-24
SE428686B (sv) * 1975-08-11 1983-07-18 Du Pont Forfarande for framstellning av antiinflammatoriskt aktiva imidazoler

Also Published As

Publication number Publication date
IT1092588B (it) 1985-07-12
HU178211B (en) 1982-03-28
CH644108A5 (en) 1984-07-13
NO148265C (no) 1983-09-07
NO148265B (no) 1983-05-30
IE780279L (en) 1978-08-09
NL7801453A (nl) 1978-08-11
AT361470B (de) 1981-03-10
IE46187B1 (en) 1983-03-23
FI69462B (fi) 1985-10-31
ES466794A1 (es) 1979-08-01
DE2805167A1 (de) 1978-08-10
FR2380275A1 (fr) 1978-09-08
FR2380275B1 (xx) 1982-01-08
GR64142B (en) 1980-01-28
AR219310A1 (es) 1980-08-15
ATA86978A (de) 1980-08-15
PT67626B (en) 1979-07-17
JPS53130664A (en) 1978-11-14
NO780433L (no) 1978-08-10
IT7820078A0 (it) 1978-02-07
SE7801467L (sv) 1978-08-10
AU3309678A (en) 1979-08-16
LU79024A1 (fr) 1979-05-25
IL53995A0 (en) 1978-04-30
DK16778A (da) 1978-08-10
FI780428A (fi) 1978-08-10
FI69462C (fi) 1986-02-10
CA1105024A (en) 1981-07-14
PT67626A (en) 1978-03-01
YU28878A (en) 1983-01-21
PH13852A (en) 1980-10-22
MX5933E (es) 1984-08-30
AU517028B2 (en) 1981-07-02
IL53995A (en) 1982-02-28
GB1564184A (en) 1980-04-02

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