FI68126C - Komposition resistent mot askorbat testanordning och foerfarande foer paovisning av en viss komponent i ett flytande testprov - Google Patents

Komposition resistent mot askorbat testanordning och foerfarande foer paovisning av en viss komponent i ett flytande testprov Download PDF

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Publication number
FI68126C
FI68126C FI803234A FI803234A FI68126C FI 68126 C FI68126 C FI 68126C FI 803234 A FI803234 A FI 803234A FI 803234 A FI803234 A FI 803234A FI 68126 C FI68126 C FI 68126C
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Finland
Prior art keywords
complex
mercury
ion
ligand
glucose
Prior art date
Application number
FI803234A
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English (en)
Finnish (fi)
Other versions
FI68126B (fi
FI803234L (fi
Inventor
Thomas Anthony Magers
John Eugene Sheats
David Lee Tabb
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Miles Lab
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Publication date
Application filed by Miles Lab filed Critical Miles Lab
Publication of FI803234L publication Critical patent/FI803234L/fi
Publication of FI68126B publication Critical patent/FI68126B/fi
Application granted granted Critical
Publication of FI68126C publication Critical patent/FI68126C/fi

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    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/26Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase
    • C12Q1/28Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving oxidoreductase involving peroxidase
    • CCHEMISTRY; METALLURGY
    • C12BIOCHEMISTRY; BEER; SPIRITS; WINE; VINEGAR; MICROBIOLOGY; ENZYMOLOGY; MUTATION OR GENETIC ENGINEERING
    • C12QMEASURING OR TESTING PROCESSES INVOLVING ENZYMES, NUCLEIC ACIDS OR MICROORGANISMS; COMPOSITIONS OR TEST PAPERS THEREFOR; PROCESSES OF PREPARING SUCH COMPOSITIONS; CONDITION-RESPONSIVE CONTROL IN MICROBIOLOGICAL OR ENZYMOLOGICAL PROCESSES
    • C12Q1/00Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions
    • C12Q1/54Measuring or testing processes involving enzymes, nucleic acids or microorganisms; Compositions therefor; Processes of preparing such compositions involving glucose or galactose
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/805Test papers
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10STECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10S435/00Chemistry: molecular biology and microbiology
    • Y10S435/81Packaged device or kit
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/14Heterocyclic carbon compound [i.e., O, S, N, Se, Te, as only ring hetero atom]
    • Y10T436/142222Hetero-O [e.g., ascorbic acid, etc.]
    • Y10T436/143333Saccharide [e.g., DNA, etc.]
    • Y10T436/144444Glucose
    • YGENERAL TAGGING OF NEW TECHNOLOGICAL DEVELOPMENTS; GENERAL TAGGING OF CROSS-SECTIONAL TECHNOLOGIES SPANNING OVER SEVERAL SECTIONS OF THE IPC; TECHNICAL SUBJECTS COVERED BY FORMER USPC CROSS-REFERENCE ART COLLECTIONS [XRACs] AND DIGESTS
    • Y10TECHNICAL SUBJECTS COVERED BY FORMER USPC
    • Y10TTECHNICAL SUBJECTS COVERED BY FORMER US CLASSIFICATION
    • Y10T436/00Chemistry: analytical and immunological testing
    • Y10T436/25Chemistry: analytical and immunological testing including sample preparation
    • Y10T436/25125Digestion or removing interfering materials

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Zoology (AREA)
  • Wood Science & Technology (AREA)
  • Proteomics, Peptides & Aminoacids (AREA)
  • Engineering & Computer Science (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Genetics & Genomics (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Biotechnology (AREA)
  • Biophysics (AREA)
  • Analytical Chemistry (AREA)
  • Biochemistry (AREA)
  • Physics & Mathematics (AREA)
  • General Engineering & Computer Science (AREA)
  • General Health & Medical Sciences (AREA)
  • Immunology (AREA)
  • Emergency Medicine (AREA)
  • Investigating Or Analyzing Non-Biological Materials By The Use Of Chemical Means (AREA)
  • Investigating Or Analysing Biological Materials (AREA)
  • Measuring Or Testing Involving Enzymes Or Micro-Organisms (AREA)
  • Food Preservation Except Freezing, Refrigeration, And Drying (AREA)
  • Dental Preparations (AREA)
  • Organic Insulating Materials (AREA)
  • Insulated Conductors (AREA)
  • Other Investigation Or Analysis Of Materials By Electrical Means (AREA)
  • Analysing Materials By The Use Of Radiation (AREA)
  • Materials For Photolithography (AREA)
  • Sealing Material Composition (AREA)

Claims (8)

1. Komposition för bestäraning av närvaron av en viss kompo-nent i ett testprov varvid kompositionen omfattar ett enzymatiskt oxiderande system, son i närvaro av denna komponent friger per-oxid, vilket leder tili en iakttagbar färgförändring dä peroxi-den reagerar med en färgproducerande indikator, son innehäller bensidin, dess färgproducerande derivat eller en blandning av dessa, och vilken komposition är känslig för störande inverkan av i provet förekommande askorbinsyra, och vilken komposition dessutom innehäller en tungmetallförening, vilken i joniserat tillständ har en oxidationspotential mindre än indikatorns oxi-dationspotential med större än askorbinsyrans oxidationspotential, kännetecknad därav, att som tungmetallförening används ett komplex av kvicksilver(II)jon och en eller flera ligander, varvid liganden binds med kovalenta bindingar tili jonen under bildning av ett vattenlösligt komplex, liganden har en oxidationspotential större än oxidationspotentialen för kvicksilver(II)jonen i komplexform, komplexets K -värde är
7 S större än 10 , och komplexet har ingen väsentligt störande inverkan pä reagenssystemet.
2. Komposition enligt patentkravet 1, kännetecknad därav, att liganden är en aminosyra, en nukleosid, en sekundär amin, en tertiär amin, en amid eller ett fosfin.
3. Komposition enligt patentkravet 2, kännetecknad därav, att liganden är sarkosin, treonin, serin, prolin, bicen, uridin, trietanolamin, dietanolamin, lauroylsarkosin eller trifenylfosfin.
4. Komposition enligt patentkravet 1, kännetecknad därav, att komplexet är kvicksilver(II)sarkosinat.
5. Komposition enligt nägot av patentkraven 1-4, kännetecknad därav, att komponenten som skall bestämmas är ett socker och att reagenssystemet omfattar ett enzym som förmär befrämja oxidationen av sockret för producerande av peroxid samt ett Minne, som aktiverar peroxidproduktionen.
FI803234A 1979-10-15 1980-10-13 Komposition resistent mot askorbat testanordning och foerfarande foer paovisning av en viss komponent i ett flytande testprov FI68126C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US06/084,611 US4288541A (en) 1979-10-15 1979-10-15 Ascorbate resistant composition, test device and method for detecting a component in a liquid test sample
US8461179 1979-10-15

Publications (3)

Publication Number Publication Date
FI803234L FI803234L (fi) 1981-04-16
FI68126B FI68126B (fi) 1985-03-29
FI68126C true FI68126C (fi) 1985-07-10

Family

ID=22186083

Family Applications (1)

Application Number Title Priority Date Filing Date
FI803234A FI68126C (fi) 1979-10-15 1980-10-13 Komposition resistent mot askorbat testanordning och foerfarande foer paovisning av en viss komponent i ett flytande testprov

Country Status (16)

Country Link
US (1) US4288541A (sv)
EP (1) EP0027236B1 (sv)
JP (1) JPS5663262A (sv)
AT (1) ATE4730T1 (sv)
AU (1) AU521370B2 (sv)
BR (1) BR8006624A (sv)
CA (1) CA1144455A (sv)
CS (1) CS250653B2 (sv)
DE (1) DE3064956D1 (sv)
DK (1) DK158995C (sv)
ES (1) ES495912A0 (sv)
FI (1) FI68126C (sv)
IE (1) IE49861B1 (sv)
IL (1) IL60779A (sv)
NO (1) NO153822C (sv)
ZA (1) ZA805030B (sv)

Families Citing this family (21)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JPS5855757A (ja) * 1981-09-29 1983-04-02 Fujirebio Inc 還元性妨害物質の除去方法
JPS5886083A (ja) * 1981-11-12 1983-05-23 Wako Pure Chem Ind Ltd グリセロ−ル−3−リン酸オキシダ−ゼの安定化剤
US4587220A (en) * 1983-03-28 1986-05-06 Miles Laboratories, Inc. Ascorbate interference-resistant composition, device and method for the determination of peroxidatively active substances
JPS60198460A (ja) * 1984-03-22 1985-10-07 Terumo Corp 試験容器
JPS60224063A (ja) * 1984-04-20 1985-11-08 Terumo Corp 試験用具
US4621049A (en) * 1984-11-19 1986-11-04 Miles Laboratories, Inc. Enzymatic high range glucose test
US5116763A (en) * 1984-11-19 1992-05-26 Miles Inc. Nonenzymatic glucose test
EP0267952A4 (en) * 1986-06-02 1989-06-27 Paul J Lawrence TEST REAGENTS AND METHODS FOR DETECTING THE PRESENCE OF BLOOD IN FECES.
US4954451A (en) * 1989-06-26 1990-09-04 Miles Inc. Agent for diminishing ascorbate interference in reagent systems and method relating thereto
US5318894A (en) * 1990-01-30 1994-06-07 Miles Inc. Composition, device and method of assaying for peroxidatively active substances
US5190863A (en) * 1990-06-29 1993-03-02 Miles Inc. Composition for determining the presence or concentration of D-β-hydroxybutyrate
JPH07119752B2 (ja) * 1990-10-08 1995-12-20 株式会社京都第一科学 レドックス反応検出用試薬組成物
AU633230B2 (en) * 1991-01-14 1993-01-21 Miles Inc. Ascorbate resistant composition and test device for detecting a component in a liquid sample
US5264348A (en) * 1991-05-13 1993-11-23 Miles Inc. Ascorbate interference-resistant composition, device and method of assaying for predetermined analyte
JPH06148168A (ja) * 1992-11-09 1994-05-27 Kyoto Daiichi Kagaku:Kk 過酸化活性物質検出用組成物
US5441872A (en) * 1993-06-04 1995-08-15 Board Of Supervisors Of Louisiana State University And Agricultural And Mechanical College Method for the analysis of Vitamin C
US5945345A (en) * 1996-08-27 1999-08-31 Metrika, Inc. Device for preventing assay interference using silver or lead to remove the interferant
US6603403B2 (en) 2000-12-12 2003-08-05 Kimberly-Clark Worldwide, Inc. Remote, wetness signaling system
US6583722B2 (en) 2000-12-12 2003-06-24 Kimberly-Clark Worldwide, Inc. Wetness signaling device
US7150995B2 (en) 2004-01-16 2006-12-19 Metrika, Inc. Methods and systems for point of care bodily fluid analysis
EP3612819A4 (en) * 2017-04-18 2021-01-27 Sun Chemical Corporation PRINTED TEST STRIPS FOR DETERMINING THE GLUCOSE CONCENTRATION IN Aqueous LIQUIDS

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE627415A (sv) * 1962-01-24
US3411887A (en) * 1964-06-15 1968-11-19 Miles Lab Diagnostic composition
US3367842A (en) * 1965-02-17 1968-02-06 Miles Lab Test composition and device for the detection of galactose in fluids
FR2215140A5 (en) * 1973-01-23 1974-08-19 Transacciones Mercantiles Sa Diagnostic test-papers for glucose - for testing urines which may contain ascorbic acid
JPS5240239B2 (sv) * 1973-09-18 1977-10-11
DE2738135A1 (de) * 1977-08-24 1979-03-01 Ewald Blees Verfahren zur bestimmung von glucose im blut

Also Published As

Publication number Publication date
IE801637L (en) 1981-04-15
IL60779A (en) 1983-10-31
CA1144455A (en) 1983-04-12
AU521370B2 (en) 1982-04-01
ATE4730T1 (de) 1983-10-15
DE3064956D1 (en) 1983-10-27
NO802907L (no) 1981-04-21
FI68126B (fi) 1985-03-29
ES8106935A1 (es) 1981-09-16
EP0027236A1 (en) 1981-04-22
AU6114780A (en) 1981-04-30
BR8006624A (pt) 1981-04-22
ZA805030B (en) 1982-04-28
CS250653B2 (en) 1987-05-14
US4288541A (en) 1981-09-08
DK158995C (da) 1991-01-07
NO153822C (no) 1986-05-28
IE49861B1 (en) 1985-12-25
DK158995B (da) 1990-08-13
JPS6339871B2 (sv) 1988-08-08
DK434580A (da) 1981-04-16
JPS5663262A (en) 1981-05-29
EP0027236B1 (en) 1983-09-21
ES495912A0 (es) 1981-09-16
FI803234L (fi) 1981-04-16
NO153822B (no) 1986-02-17

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Owner name: MILES LABORATORIES, INC.