FI67386C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat Download PDF

Info

Publication number
FI67386C
FI67386C FI801472A FI801472A FI67386C FI 67386 C FI67386 C FI 67386C FI 801472 A FI801472 A FI 801472A FI 801472 A FI801472 A FI 801472A FI 67386 C FI67386 C FI 67386C
Authority
FI
Finland
Prior art keywords
formula
compounds
tetramethyl
naphthyl
acetyl
Prior art date
Application number
FI801472A
Other languages
English (en)
Finnish (fi)
Swedish (sv)
Other versions
FI801472A7 (fi
FI67386B (fi
Inventor
Werner Bollag
Pierre-Charles Wyss
Original Assignee
Hoffmann La Roche
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Hoffmann La Roche filed Critical Hoffmann La Roche
Publication of FI801472A7 publication Critical patent/FI801472A7/fi
Priority to FI840363A priority Critical patent/FI68628C/fi
Priority to FI840362A priority patent/FI69471C/fi
Publication of FI67386B publication Critical patent/FI67386B/fi
Application granted granted Critical
Publication of FI67386C publication Critical patent/FI67386C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H3/00Compounds containing only hydrogen atoms and saccharide radicals having only carbon, hydrogen, and oxygen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C33/00Unsaturated compounds having hydroxy or O-metal groups bound to acyclic carbon atoms
    • C07C33/38Alcohols containing six-membered aromatic rings and other rings and having unsaturation outside the aromatic rings
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P17/00Drugs for dermatological disorders
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P29/00Non-central analgesic, antipyretic or antiinflammatory agents, e.g. antirheumatic agents; Non-steroidal antiinflammatory drugs [NSAID]
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P35/00Antineoplastic agents
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P37/00Drugs for immunological or allergic disorders
    • A61P37/08Antiallergic agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C45/00Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds
    • C07C45/45Preparation of compounds having >C = O groups bound only to carbon or hydrogen atoms; Preparation of chelates of such compounds by condensation
    • C07C45/46Friedel-Crafts reactions
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C49/00Ketones; Ketenes; Dimeric ketenes; Ketonic chelates
    • C07C49/76Ketones containing a keto group bound to a six-membered aromatic ring
    • C07C49/782Ketones containing a keto group bound to a six-membered aromatic ring polycyclic
    • C07C49/792Ketones containing a keto group bound to a six-membered aromatic ring polycyclic containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C63/00Compounds having carboxyl groups bound to a carbon atoms of six-membered aromatic rings
    • C07C63/33Polycyclic acids
    • C07C63/49Polycyclic acids containing rings other than six-membered aromatic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H13/00Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids
    • C07H13/02Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids
    • C07H13/08Compounds containing saccharide radicals esterified by carbonic acid or derivatives thereof, or by organic acids, e.g. phosphonic acids by carboxylic acids having the esterifying carboxyl radicals directly attached to carbocyclic rings
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/02Acyclic radicals, not substituted by cyclic structures
    • C07H15/04Acyclic radicals, not substituted by cyclic structures attached to an oxygen atom of the saccharide radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07HSUGARS; DERIVATIVES THEREOF; NUCLEOSIDES; NUCLEOTIDES; NUCLEIC ACIDS
    • C07H15/00Compounds containing hydrocarbon or substituted hydrocarbon radicals directly attached to hetero atoms of saccharide radicals
    • C07H15/18Acyclic radicals, substituted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Health & Medical Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Molecular Biology (AREA)
  • Genetics & Genomics (AREA)
  • Biotechnology (AREA)
  • Biochemistry (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Veterinary Medicine (AREA)
  • Pharmacology & Pharmacy (AREA)
  • General Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Crystallography & Structural Chemistry (AREA)
  • Dermatology (AREA)
  • Rheumatology (AREA)
  • Pain & Pain Management (AREA)
  • Immunology (AREA)
  • Pulmonology (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Saccharide Compounds (AREA)
FI801472A 1979-06-21 1980-05-07 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat FI67386C (fi)

Priority Applications (2)

Application Number Priority Date Filing Date Title
FI840363A FI68628C (fi) 1979-06-21 1984-01-30 Foerfarande foer framstaellning av nya terapeutiskt verksamma sockerderivat
FI840362A FI69471C (fi) 1979-06-21 1984-01-30 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH580879 1979-06-21
CH580879 1979-06-21

Publications (3)

Publication Number Publication Date
FI801472A7 FI801472A7 (fi) 1980-12-22
FI67386B FI67386B (fi) 1984-11-30
FI67386C true FI67386C (fi) 1985-03-11

Family

ID=4299652

Family Applications (1)

Application Number Title Priority Date Filing Date
FI801472A FI67386C (fi) 1979-06-21 1980-05-07 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat

Country Status (22)

Country Link
US (1) US4316983A (no)
EP (1) EP0021339B1 (no)
JP (1) JPS567798A (no)
KR (2) KR840000678B1 (no)
AR (2) AR225312A1 (no)
AT (1) ATE2434T1 (no)
AU (1) AU530478B2 (no)
CA (1) CA1134819A (no)
DE (1) DE3061891D1 (no)
DK (1) DK154650C (no)
ES (2) ES8104322A1 (no)
FI (1) FI67386C (no)
GR (1) GR69283B (no)
HU (1) HU184915B (no)
IE (1) IE50463B1 (no)
IL (1) IL60324A (no)
MC (1) MC1338A1 (no)
NO (1) NO148644C (no)
NZ (1) NZ194061A (no)
PH (1) PH16243A (no)
PT (1) PT71435B (no)
ZA (1) ZA803538B (no)

Families Citing this family (12)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4987223A (en) * 1981-12-23 1991-01-22 Choay S.A. Derivatives of the uronic acid
US4388457A (en) * 1982-02-11 1983-06-14 University Patents, Inc. Phyllanthostatin compounds
CH661516A5 (de) * 1983-12-08 1987-07-31 Hoffmann La Roche Phenylnonatetraenoylzuckerderivate.
AU582758B2 (en) * 1984-06-28 1989-04-13 Mect Corporation Sialic acid derivatives, galactose derivatives and method for producing the same
CH667868A5 (fr) * 1984-09-05 1988-11-15 Oreal Derives du benzonorbornene, leurs procedes de preparation et compositions medicamenteuse et cosmetique les contenant.
LU85726A1 (fr) * 1985-01-10 1986-08-04 Cird Nouveaux derives naphtaleniques du benzonorbornene,leur procede de preparation et compositions medicamenteuse et cosmetique les contenant
ATE94395T1 (de) * 1986-05-09 1993-10-15 Pulverer Gerhard Verwendung von spezifischen monosacchariden zur herstellung eines arzneimittels zur verhinderung von metastasen maligner tumore.
JPH03502327A (ja) * 1988-01-19 1991-05-30 ボード・オブ・リージェンツ,ザ・ユニバーシティ・オブ・テキサス・システム 3’‐デアミノドキソルビシンのエステル体、そのリポソーム組成物およびその使用方法
US4943563A (en) * 1988-10-03 1990-07-24 Cornell Research Foundation, Inc. 2,3,4-triacylhexose insect repellants
DE3929355A1 (de) * 1989-09-04 1991-03-07 Boehringer Mannheim Gmbh Verfahren zur spezifischen bestimmung von pankreas-(alpha)-amylase
JP2674843B2 (ja) * 1989-10-31 1997-11-12 新日本製鐵株式会社 鋳鉄用被覆アーク溶接棒
US5523398A (en) * 1994-08-31 1996-06-04 The Center For Innovative Technology Cellulose derivatives with a low degree of substitution

Family Cites Families (6)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3629238A (en) * 1968-09-20 1971-12-21 Sumitomo Chemical Co Novel glucuronides of 3-indolylaliphatic acid derivatives
FR2141532B1 (no) * 1971-06-14 1974-08-23 Anvar
JPS51125362A (en) * 1975-04-17 1976-11-01 Hayashibara Biochem Lab Inc Process for synthesizing echinatin glycosides
FR2307820A1 (fr) * 1975-04-17 1976-11-12 Hayashibara Seibutsu Chem Inst Glycosides d'echinatine et leur preparation
LU77254A1 (no) * 1977-05-04 1979-01-18
DK159967C (da) * 1977-12-22 1991-06-03 Hoffmann La Roche Analogifremgangsmaade til fremstilling af terapeutisk aktive stilbenderivater

Also Published As

Publication number Publication date
GR69283B (no) 1982-05-13
DK262480A (da) 1980-12-22
NO801862L (no) 1980-12-22
FI801472A7 (fi) 1980-12-22
EP0021339B1 (de) 1983-02-09
ES498607A0 (es) 1981-12-01
FI67386B (fi) 1984-11-30
NO148644B (no) 1983-08-08
DK154650B (da) 1988-12-05
AR225312A1 (es) 1982-03-15
PH16243A (en) 1983-08-11
IL60324A0 (en) 1980-09-16
EP0021339A1 (de) 1981-01-07
PT71435B (en) 1981-10-22
AU530478B2 (en) 1983-07-14
AU5902980A (en) 1981-01-08
KR840000678B1 (ko) 1984-05-18
PT71435A (en) 1980-07-01
JPH0131518B2 (no) 1989-06-26
NZ194061A (en) 1982-09-07
IE801280L (en) 1980-12-21
JPS567798A (en) 1981-01-27
DK154650C (da) 1989-05-01
HU184915B (en) 1984-11-28
US4316983A (en) 1982-02-23
NO148644C (no) 1983-11-16
ES8201175A1 (es) 1981-12-01
ES492616A0 (es) 1981-04-16
KR840000850B1 (ko) 1984-06-19
ES8104322A1 (es) 1981-04-16
KR830002800A (ko) 1983-05-30
MC1338A1 (fr) 1981-04-21
DE3061891D1 (en) 1983-03-17
CA1134819A (en) 1982-11-02
IL60324A (en) 1984-01-31
AR229247A1 (es) 1983-07-15
ATE2434T1 (de) 1983-03-15
IE50463B1 (en) 1986-04-30
ZA803538B (en) 1981-06-24

Similar Documents

Publication Publication Date Title
Hanessian et al. A stereospecifie, total synthesis of thromboxane B2
FI67386C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat
EP0097059A2 (en) Skin treatment compositions
Jolad et al. Constituents of Trichilia hispida (Meliaceae). 4. Hispidols A and B, two new tirucallane triterpenoids
FUJITA et al. Antitumor activity of acylated oridonin
KOMIYAMA et al. Structural study of a new antitumor antibiotic, kazusamycin
US4046914A (en) Therapeutically active substituted saturated and mono-and polyunsaturated alkyl-glycerylethers
CH661516A5 (de) Phenylnonatetraenoylzuckerderivate.
Achmatowicz Jr et al. The oxidation of diterpenoid alkaloids
EP0182851B1 (en) Primycin components and process for the separation of the antibiotic complex
FI101796B (fi) Uusia -glukosidaasi-inhibiittoreita
US4055717A (en) 9-(3-O-Acyl-β-D-arabinofuranosyl)adenine compounds, 9-(2,3-di-O-acyl-β-D-arabinofuranosyl)-adenine compounds, and method for their production
EP0169716A2 (en) Pharmaceutical composition and method for producing antiallergic activity
Katsui et al. Phytosterols and triterpenes in the roots of the “kidney bean”(Phaseolus vulgaris L.)
EP0687673A1 (en) Oxazole derivatives as antitumoral agents
IKEKAWA et al. Studies on Synthesis of 3-Ο-Alkyl-D-glucose and 3-Ο-Alkyl-D-allose Derivatives and Their Biological Activities
WO1987005023A1 (fr) Derives d'antibiotiques de cervinomycine et procede de preparation
FI69471C (fi) Foerfarande foer framstaellning av nya terapeutiskt anvaendbara sockerderivat
EP0104631B1 (en) Clavulone derivatives, process for preparing the same, and use of said compounds
DE1643521B2 (de) 4'-demethyl-epipodophyllotoxin-beta-d- glucosidderivate sowie ein verfahren zu ihrer herstellung und arzneimittel mit einem gehalt dieser verbindungen
US3442911A (en) Glycyrrhetyl glucosiduronates
Lown et al. 10-Acetyl-10-hydroxyxantho [2, 3-f] tetralin 8-glycosides as angular chromophore analogs of anthracyclines: synthesis, redox properties, microsomal oxygen consumption, and antileukemic evaluation
US4647412A (en) Anti-tumor derivatives of butanediol and process of preparation
EP0169512B1 (en) Novel tylosin derivatives
Jalmakhanbetova et al. Synthesis and Investigation of Biological Activity of a Number of New Betulonic Acid Derivatives Containing 1, 2, 3-Triazole Fragments

Legal Events

Date Code Title Description
MM Patent lapsed

Owner name: F. HOFFMANN-LA ROCHE AG