FI66870C - Foerfarande foer framstaellning av ny terapeutiskt anvaendbar 7-brom-1,5-dihydro-3,6-dimetyl-imidazo(2,1b)kinazolin-2(3h)-on och derivat daerav - Google Patents
Foerfarande foer framstaellning av ny terapeutiskt anvaendbar 7-brom-1,5-dihydro-3,6-dimetyl-imidazo(2,1b)kinazolin-2(3h)-on och derivat daerav Download PDFInfo
- Publication number
- FI66870C FI66870C FI801910A FI801910A FI66870C FI 66870 C FI66870 C FI 66870C FI 801910 A FI801910 A FI 801910A FI 801910 A FI801910 A FI 801910A FI 66870 C FI66870 C FI 66870C
- Authority
- FI
- Finland
- Prior art keywords
- dihydro
- quinazolin
- bromo
- formula
- compounds
- Prior art date
Links
Classifications
-
- C—CHEMISTRY; METALLURGY
- C07—ORGANIC CHEMISTRY
- C07D—HETEROCYCLIC COMPOUNDS
- C07D487/00—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
- C07D487/02—Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
- C07D487/04—Ortho-condensed systems
Landscapes
- Chemical & Material Sciences (AREA)
- Organic Chemistry (AREA)
- Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
- Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
Applications Claiming Priority (4)
| Application Number | Priority Date | Filing Date | Title |
|---|---|---|---|
| US06/050,395 US4256748A (en) | 1977-07-25 | 1979-06-20 | Imidazo[2,1-b]quinazolin-2(3H)-ones and pharmaceutical compositions for treatment and prophylaxis of cardiac insufficiency and cardiac failure |
| US5039579 | 1979-06-20 | ||
| CH360080 | 1980-05-08 | ||
| CH360080 | 1980-05-08 |
Publications (3)
| Publication Number | Publication Date |
|---|---|
| FI801910A FI801910A (fi) | 1980-12-21 |
| FI66870B FI66870B (fi) | 1984-08-31 |
| FI66870C true FI66870C (fi) | 1984-12-10 |
Family
ID=25693404
Family Applications (1)
| Application Number | Title | Priority Date | Filing Date |
|---|---|---|---|
| FI801910A FI66870C (fi) | 1979-06-20 | 1980-06-13 | Foerfarande foer framstaellning av ny terapeutiskt anvaendbar 7-brom-1,5-dihydro-3,6-dimetyl-imidazo(2,1b)kinazolin-2(3h)-on och derivat daerav |
Country Status (14)
| Country | Link |
|---|---|
| EP (1) | EP0021338B1 (no) |
| AU (1) | AU538119B2 (no) |
| CA (1) | CA1131631A (no) |
| DE (1) | DE3065273D1 (no) |
| DK (1) | DK259380A (no) |
| ES (3) | ES492573A0 (no) |
| FI (1) | FI66870C (no) |
| IL (1) | IL60325A (no) |
| MC (1) | MC1332A1 (no) |
| NO (1) | NO801843L (no) |
| NZ (1) | NZ194046A (no) |
| PH (1) | PH16369A (no) |
| PT (1) | PT71411B (no) |
| YU (1) | YU161580A (no) |
Families Citing this family (10)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| EP0054180A3 (de) * | 1980-12-16 | 1982-12-01 | F. HOFFMANN-LA ROCHE & CO. Aktiengesellschaft | Verfahren zur Herstellung eines Imidazochinazolinonderivates |
| US4783467A (en) * | 1985-06-05 | 1988-11-08 | Pfizer Inc. | Tetrahydroimidazoquinazolinone inotropic agents |
| US6388073B1 (en) * | 2000-07-26 | 2002-05-14 | Shire Us Inc. | Method for the manufacture of anagrelide |
| US7700608B2 (en) | 2004-08-04 | 2010-04-20 | Shire Holdings Ag | Quinazoline derivatives and their use in the treatment of thrombocythemia |
| US8436006B2 (en) | 2004-08-06 | 2013-05-07 | Jansssen Pharmaceutica N.V. | 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE) |
| US8426429B2 (en) | 2004-08-06 | 2013-04-23 | Jansssen Pharmaceutica N.V. | 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE) |
| US8383637B2 (en) | 2004-08-06 | 2013-02-26 | Jansssen Pharmaceutica N.V. | 2-amino-quinazoline derivatives useful as inhibitors of β-secretase (BACE) |
| US7910597B2 (en) | 2006-11-28 | 2011-03-22 | Shire Llc | Substituted quinazolines |
| GB0623750D0 (en) * | 2006-11-28 | 2007-01-10 | Shire Llc | Substituted quinazolines |
| US8304420B2 (en) | 2006-11-28 | 2012-11-06 | Shire Llc | Substituted quinazolines for reducing platelet count |
Family Cites Families (5)
| Publication number | Priority date | Publication date | Assignee | Title |
|---|---|---|---|---|
| US3932407A (en) * | 1973-11-19 | 1976-01-13 | Bristol-Myers Company | Optionally substituted 1,2,3,5-tetrahydroimidezo(2,1-b)-quinazolin-2-ones and 6(H)-1,2,3,4-tetrahydropyimido(2,1-b)quinazolin-2-ones |
| BE794964A (fr) * | 1972-02-04 | 1973-08-02 | Bristol Myers Co | Nouveaux agents hypotenseurs et procede pour les preparer |
| US3988340A (en) * | 1975-01-23 | 1976-10-26 | Bristol-Myers Company | 6-Alkoxymethyl-1,2,3,5-tetrahydroimidazo[2,1-b]quinazolin-2-ones and 7-alkoxymethyl-6-[H]-1,2,3,4-tetrahydropyrimido[2,1-b]quinazolin-2-ones |
| NL7807507A (nl) * | 1977-07-25 | 1979-01-29 | Hoffmann La Roche | Tricyclische verbindingen. |
| US4146718A (en) * | 1978-04-10 | 1979-03-27 | Bristol-Myers Company | Alkyl 5,6-dichloro-3,4-dihydro-2(1h)-iminoquinazoline-3-acetate hydrohalides |
-
1980
- 1980-06-06 CA CA353,659A patent/CA1131631A/en not_active Expired
- 1980-06-13 NZ NZ194046A patent/NZ194046A/xx unknown
- 1980-06-13 FI FI801910A patent/FI66870C/fi not_active IP Right Cessation
- 1980-06-16 IL IL60325A patent/IL60325A/xx unknown
- 1980-06-17 DK DK259380A patent/DK259380A/da not_active Application Discontinuation
- 1980-06-17 AU AU59339/80A patent/AU538119B2/en not_active Ceased
- 1980-06-18 PT PT71411A patent/PT71411B/pt unknown
- 1980-06-18 MC MC801454A patent/MC1332A1/xx unknown
- 1980-06-18 DE DE8080103396T patent/DE3065273D1/de not_active Expired
- 1980-06-18 EP EP80103396A patent/EP0021338B1/de not_active Expired
- 1980-06-19 YU YU01615/80A patent/YU161580A/xx unknown
- 1980-06-19 ES ES492573A patent/ES492573A0/es active Granted
- 1980-06-19 NO NO801843A patent/NO801843L/no unknown
- 1980-06-20 PH PH24171A patent/PH16369A/en unknown
-
1981
- 1981-02-16 ES ES499454A patent/ES8201164A1/es not_active Expired
- 1981-02-16 ES ES499455A patent/ES499455A0/es active Granted
Also Published As
| Publication number | Publication date |
|---|---|
| EP0021338A1 (de) | 1981-01-07 |
| DE3065273D1 (de) | 1983-11-17 |
| ES8105321A1 (es) | 1981-06-01 |
| PT71411B (en) | 1981-12-11 |
| MC1332A1 (fr) | 1981-04-21 |
| AU538119B2 (en) | 1984-08-02 |
| IL60325A (en) | 1983-06-15 |
| ES8206524A1 (es) | 1982-08-16 |
| ES499454A0 (es) | 1981-12-01 |
| ES499455A0 (es) | 1982-08-16 |
| EP0021338B1 (de) | 1983-10-12 |
| NO801843L (no) | 1980-12-22 |
| ES492573A0 (es) | 1981-06-01 |
| PT71411A (en) | 1980-07-01 |
| AU5933980A (en) | 1981-01-08 |
| IL60325A0 (en) | 1980-09-16 |
| NZ194046A (en) | 1982-05-25 |
| YU161580A (en) | 1983-04-30 |
| PH16369A (en) | 1983-09-14 |
| CA1131631A (en) | 1982-09-14 |
| FI801910A (fi) | 1980-12-21 |
| ES8201164A1 (es) | 1981-12-01 |
| DK259380A (da) | 1980-12-21 |
| FI66870B (fi) | 1984-08-31 |
Similar Documents
| Publication | Publication Date | Title |
|---|---|---|
| DE60005850T2 (de) | Imidazo[1,2-a]pyridin- und pyrazolo[2,3-a]pyridinderivate | |
| FI66870C (fi) | Foerfarande foer framstaellning av ny terapeutiskt anvaendbar 7-brom-1,5-dihydro-3,6-dimetyl-imidazo(2,1b)kinazolin-2(3h)-on och derivat daerav | |
| EP0042593A1 (de) | Aryloxypropanolamine, Verfahren zu ihrer Herstellung und diese Verbindungen enthaltende Arzneimittel | |
| DD231350A5 (de) | Verfahren zur herstellung von 6-phenyl-4,5-dihydro-3(2h)-pyridazinon-verbindungen und ihren salzen | |
| Patel et al. | Synthesis of some novel thiosemicarbazone derivatives having anti-cancer, anti-HIV as well as anti-bacterial activity | |
| MEP45408A (en) | 6-position substituted indoline, production and use thereof as a medicament | |
| EP0238459B1 (en) | Substituted indoloquinoxalines | |
| KR101932146B1 (ko) | Pi3k를 억제하는 신규한 퀴나졸리논 유도체 및 이를 포함하는 약학적 조성물 | |
| EP1778647A1 (en) | New derivatives of 4, 5, 6, 7-tetrabromobenzimidazole and method of their preparation | |
| US20170015672A1 (en) | Substituted pyrrolo[2,3-d]pyrimidines for selectively targeting tumor cells with fr-alpha and fr-beta type receptors | |
| Pages et al. | 1-Amino-2-(4-imidazolyl) cyclopropanecarboxylic Acid1a | |
| FI77864B (fi) | Foerfarande foer framstaellning av ett nytt, terapeutiskt anvaendbart 7-piperidino-1,2,3,5-tetrahydroimidazo /2,1-b/kinazolin-2-on. | |
| DD297960A5 (de) | Indenoindolverbindungen ii | |
| CZ390992A3 (en) | Pyrimidine derivatives, process of their preparation and use as substances for increase of anti-tumor activity | |
| US4439619A (en) | Fluorinated pentene diamine derivatives | |
| AU640709B2 (en) | 1,3,5-triazine derivatives, processes for their preparation and pharmaceutical compositions containing them | |
| US3882134A (en) | 1-Substituted-3,5-dipyridyl-1,2,4-triazoles | |
| Sathishkumar et al. | Synthesis, characterization and anti-inflammatory evaluation of novel substituted tetrazolodiazepine derivatives | |
| US3453365A (en) | Substituted quinoxalines as fungicides | |
| US3705174A (en) | Polyhaloalkyl benzimidazoles | |
| AU2004298907B2 (en) | Use of a compound having two gold (I) atoms each covalently bonded to a carbon atom in a covalent link connecting the two gold (I) atoms for the treatment of cancer | |
| Bruni et al. | Synthesis and study of the anti-inflammatory properties of some pyrazolo [1, 5-a] pyrimidine derivatives | |
| FI57589B (fi) | Foerfarande foer framstaellning av blodtrycket saenkande 6-substituerade 3-karbetoksihydrazinopyridaziner | |
| SE463154B (sv) | 6-fenetylaminoalkyl-furo(3,4-c)pyridinderivat,framstaellning daerav och terapeutiska kompositioner innehaallande dem | |
| DK175885B1 (da) | Anvendelse af 1,2,4-benzotriazinoxider som strålingssensibiliserende midler og selektive cytotoksiske midler |
Legal Events
| Date | Code | Title | Description |
|---|---|---|---|
| MM | Patent lapsed |
Owner name: F. HOFFMANN-LA ROCHE & CO. AG |