FI64363C - Foerfarande foer framstaellning av terapeutiskt anvaendbara sustituerade difenylsulfider - Google Patents

Foerfarande foer framstaellning av terapeutiskt anvaendbara sustituerade difenylsulfider Download PDF

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Publication number
FI64363C
FI64363C FI762077A FI762077A FI64363C FI 64363 C FI64363 C FI 64363C FI 762077 A FI762077 A FI 762077A FI 762077 A FI762077 A FI 762077A FI 64363 C FI64363 C FI 64363C
Authority
FI
Finland
Prior art keywords
alkyl
carbon atoms
group
formula
sulfide
Prior art date
Application number
FI762077A
Other languages
English (en)
Finnish (fi)
Other versions
FI64363B (fi
FI762077A (bg
Inventor
Nariman Bomanshaw Mehta
Lawrence Edward Brieaddy
Original Assignee
Wellcome Found
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Wellcome Found filed Critical Wellcome Found
Publication of FI762077A publication Critical patent/FI762077A/fi
Publication of FI64363B publication Critical patent/FI64363B/fi
Application granted granted Critical
Publication of FI64363C publication Critical patent/FI64363C/fi

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Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/16—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms
    • C07D295/18—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms acylated on ring nitrogen atoms by radicals derived from carboxylic acids, or sulfur or nitrogen analogues thereof
    • C07D295/182—Radicals derived from carboxylic acids
    • C07D295/192—Radicals derived from carboxylic acids from aromatic carboxylic acids
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/24—Antidepressants
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P25/00—Drugs for disorders of the nervous system
    • A61P25/26—Psychostimulants, e.g. nicotine, cocaine
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07C—ACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C323/00—Thiols, sulfides, hydropolysulfides or polysulfides substituted by halogen, oxygen or nitrogen atoms, or by sulfur atoms not being part of thio groups
    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D295/00—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms
    • C07D295/04—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms
    • C07D295/08—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms
    • C07D295/096—Heterocyclic compounds containing polymethylene-imine rings with at least five ring members, 3-azabicyclo [3.2.2] nonane, piperazine, morpholine or thiomorpholine rings, having only hydrogen atoms directly attached to the ring carbon atoms with substituted hydrocarbon radicals attached to ring nitrogen atoms substituted by singly bound oxygen or sulfur atoms with the ring nitrogen atoms and the oxygen or sulfur atoms separated by carbocyclic rings or by carbon chains interrupted by carbocyclic rings

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Psychiatry (AREA)
  • Neurology (AREA)
  • Neurosurgery (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Engineering & Computer Science (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Biomedical Technology (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Pain & Pain Management (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Acyclic And Carbocyclic Compounds In Medicinal Compositions (AREA)
FI762077A 1975-07-21 1976-07-19 Foerfarande foer framstaellning av terapeutiskt anvaendbara sustituerade difenylsulfider FI64363C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
US05/597,697 US3997540A (en) 1975-07-21 1975-07-21 O [(O-piperazinocarbonyl-phenyl)-thio]-benzoates
US59769775 1975-07-21

Publications (3)

Publication Number Publication Date
FI762077A FI762077A (bg) 1977-01-22
FI64363B FI64363B (fi) 1983-07-29
FI64363C true FI64363C (fi) 1983-11-10

Family

ID=24392586

Family Applications (1)

Application Number Title Priority Date Filing Date
FI762077A FI64363C (fi) 1975-07-21 1976-07-19 Foerfarande foer framstaellning av terapeutiskt anvaendbara sustituerade difenylsulfider

Country Status (28)

Country Link
US (6) US3997540A (bg)
JP (1) JPS5214737A (bg)
AT (1) AT356079B (bg)
AU (1) AU500698B2 (bg)
BE (1) BE844298A (bg)
CA (1) CA1081696A (bg)
CH (2) CH631700A5 (bg)
DE (1) DE2632400A1 (bg)
DK (1) DK325776A (bg)
ES (1) ES449939A1 (bg)
FI (1) FI64363C (bg)
FR (2) FR2318622A1 (bg)
GB (1) GB1561072A (bg)
HK (1) HK14483A (bg)
IE (1) IE43278B1 (bg)
IL (1) IL50062A (bg)
IT (1) IT1066007B (bg)
LU (1) LU75416A1 (bg)
MC (1) MC1113A1 (bg)
MY (1) MY8400101A (bg)
NL (1) NL7607975A (bg)
NZ (1) NZ181503A (bg)
PH (1) PH15375A (bg)
PT (1) PT65382B (bg)
SE (2) SE428296B (bg)
SG (1) SG4683G (bg)
SU (1) SU697050A3 (bg)
ZA (1) ZA764267B (bg)

Families Citing this family (11)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US4056632A (en) * 1975-07-21 1977-11-01 Burroughs Wellcome Co. 2-Hydroxymethyl-2'-aminomethyl-diphenylsulfides and method of use
DE2732750A1 (de) * 1977-07-20 1979-02-08 Merck Patent Gmbh Basische thioaether und verfahren zu ihrer herstellung
JPS55325A (en) * 1978-06-16 1980-01-05 Kyowa Hakko Kogyo Co Ltd Novel benzamide compound
FR2470780A1 (fr) * 1979-12-07 1981-06-12 Inst Francais Du Petrole Nouveaux oligomeres de thio-p-phenylene dicarboxy-telecheliques, leur preparation et leur utilisation dans le domaine des polycondensats segmentes
ES2052890T3 (es) * 1988-10-10 1994-07-16 Akzo Nv Un metodo para la sintesis de compuestos aromaticos di- y trisubstituidos.
EP0396827A1 (en) * 1989-05-09 1990-11-14 SPOFA Spojené Podniky Pro Zdravotnickou Vyrobu 2-Phenylthiobenzylamine dervivatives and acid addition salts thereof
GB8913011D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Anticonvulsant pyrazines
GB8912971D0 (en) * 1989-06-06 1989-07-26 Wellcome Found Halogen substituted diphenylsulfides
AR005237A1 (es) 1995-11-08 1999-04-28 Smithkline Beecham Corp Procedimiento para la preparacion de derivados de ciclopenteno condensados con anillos aromaticos, intermediarios y procedimientos para su preparacion, yderivados de ciclopenteno.
SI1648922T1 (sl) 2003-07-31 2011-03-31 Tranzyme Pharma Inc Prostorsko opredeljene makrocikliäśne spojine uporabne za odkrivanje zdravil
US8088733B2 (en) * 2006-07-06 2012-01-03 Tranzyme Pharma Inc. Methods of using macrocyclic agonists of the ghrelin receptor for treatment of gastrointestinal motility disorders

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US1769423A (en) * 1927-05-27 1930-07-01 Chem Ind Basel Sulfides of aromatic compounds and process of making same
US2454260A (en) * 1946-02-12 1948-11-16 Hoffmann La Roche Preparation of metal mercaptides of amino-aryl mercaptans
US3514480A (en) * 1967-01-19 1970-05-26 Standard Oil Co Process for producing sulfur containing aromatic carboxylic acids
US3682968A (en) * 1969-06-25 1972-08-08 Merck & Co Inc Anti-inflammatory salicylic acid derivatives
US3884922A (en) * 1969-07-31 1975-05-20 Yoshitomi Pharmaceutical 11-(4-Pyridylalkyl-piperazino)-dibenzothiazepines
US3803143A (en) * 1969-09-08 1974-04-09 Eisai Co Ltd 6-amino alkylene 6,7-dihydro-5h-dibenzo (b,g),(1,5)thiazocines
NL7013205A (bg) * 1969-09-22 1971-03-24
US3674844A (en) * 1970-04-20 1972-07-04 Merck & Co Inc Salicylic acid derivatives
US3824243A (en) * 1970-10-23 1974-07-16 E Henderson Mono-o-phthalyl piperazine and mono-piperazine mono-phthalate di-salts
US3927093A (en) * 1972-10-10 1975-12-16 Squibb & Sons Inc 2-(O-aminophenylthio)benzyl alcohols

Also Published As

Publication number Publication date
US4091100A (en) 1978-05-23
US4095027A (en) 1978-06-13
US4061863A (en) 1977-12-06
MC1113A1 (fr) 1977-05-18
FI64363B (fi) 1983-07-29
IL50062A (en) 1980-07-31
JPS5214737A (en) 1977-02-03
SE8007171L (sv) 1980-10-14
SE7608203L (sv) 1977-01-22
US3997540A (en) 1976-12-14
FR2318622B1 (bg) 1979-01-19
IE43278B1 (en) 1981-01-28
CH636603A5 (de) 1983-06-15
FI762077A (bg) 1977-01-22
ZA764267B (en) 1978-03-29
SG4683G (en) 1983-09-09
DE2632400C2 (bg) 1988-06-09
SU697050A3 (ru) 1979-11-05
IL50062A0 (en) 1976-09-30
PT65382B (en) 1978-06-08
IT1066007B (it) 1985-03-04
GB1561072A (en) 1980-02-13
AU500698B2 (en) 1979-05-31
BE844298A (fr) 1977-01-19
FR2378026A1 (fr) 1978-08-18
PT65382A (en) 1976-08-01
ATA530976A (de) 1979-09-15
US4103020A (en) 1978-07-25
MY8400101A (en) 1984-12-31
PH15375A (en) 1982-12-10
IE43278L (en) 1977-01-21
CA1081696A (en) 1980-07-15
JPS6113468B2 (bg) 1986-04-14
DK325776A (da) 1977-01-22
FR2318622A1 (fr) 1977-02-18
ES449939A1 (es) 1977-07-01
LU75416A1 (bg) 1977-04-06
NL7607975A (nl) 1977-01-25
FR2378026B1 (bg) 1980-10-31
US4123555A (en) 1978-10-31
SE428296B (sv) 1983-06-20
HK14483A (en) 1983-05-06
NZ181503A (en) 1978-07-28
CH631700A5 (de) 1982-08-31
AT356079B (de) 1980-04-10
AU1602076A (en) 1978-01-26
DE2632400A1 (de) 1977-02-24

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Owner name: THE WELLCOME FOUNDATION LIMITED