FI63674C - Foerfarande foer isolering och rening av immunologiskt aktivt polyribosylribitolfosfat (prp) - Google Patents

Foerfarande foer isolering och rening av immunologiskt aktivt polyribosylribitolfosfat (prp) Download PDF

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Publication number
FI63674C
FI63674C FI783269A FI783269A FI63674C FI 63674 C FI63674 C FI 63674C FI 783269 A FI783269 A FI 783269A FI 783269 A FI783269 A FI 783269A FI 63674 C FI63674 C FI 63674C
Authority
FI
Finland
Prior art keywords
prp
haemophilus influenzae
influenzae type
phosphate buffer
known per
Prior art date
Application number
FI783269A
Other languages
English (en)
Finnish (fi)
Other versions
FI783269A (fi
FI63674B (fi
Inventor
Joseph S-C Kuo
Original Assignee
American Cyanamid Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US05/846,466 external-priority patent/US4196192A/en
Priority claimed from US05/846,488 external-priority patent/US4220717A/en
Application filed by American Cyanamid Co filed Critical American Cyanamid Co
Publication of FI783269A publication Critical patent/FI783269A/fi
Application granted granted Critical
Publication of FI63674B publication Critical patent/FI63674B/fi
Publication of FI63674C publication Critical patent/FI63674C/fi

Links

Classifications

    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K31/00—Medicinal preparations containing organic active ingredients
    • A61K31/70—Carbohydrates; Sugars; Derivatives thereof
    • A61K31/715—Polysaccharides, i.e. having more than five saccharide radicals attached to each other by glycosidic linkages; Derivatives thereof, e.g. ethers, esters
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/099—Bordetella
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K39/02—Bacterial antigens
    • A61K39/102—Pasteurellales, e.g. Actinobacillus, Pasteurella; Haemophilus
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61K—PREPARATIONS FOR MEDICAL, DENTAL OR TOILETRY PURPOSES
    • A61K39/00—Medicinal preparations containing antigens or antibodies
    • A61K2039/70—Multivalent vaccine

Landscapes

  • Health & Medical Sciences (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Epidemiology (AREA)
  • Public Health (AREA)
  • Medicinal Chemistry (AREA)
  • Veterinary Medicine (AREA)
  • General Health & Medical Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Chemical & Material Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • Mycology (AREA)
  • Immunology (AREA)
  • Microbiology (AREA)
  • Molecular Biology (AREA)
  • Medicines Containing Antibodies Or Antigens For Use As Internal Diagnostic Agents (AREA)
  • Micro-Organisms Or Cultivation Processes Thereof (AREA)
  • Medicines Containing Material From Animals Or Micro-Organisms (AREA)
  • Preparation Of Compounds By Using Micro-Organisms (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI783269A 1977-10-28 1978-10-26 Foerfarande foer isolering och rening av immunologiskt aktivt polyribosylribitolfosfat (prp) FI63674C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US05/846,466 US4196192A (en) 1977-10-28 1977-10-28 Combined Haemophilus influenzae type b and pertussis vaccine
US84646677 1977-10-28
US84648877 1977-12-22
US05/846,488 US4220717A (en) 1977-12-22 1977-12-22 Isolation and purification of polyribosyl ribitol phosphate from Haemophilus influenzae type b.

Publications (3)

Publication Number Publication Date
FI783269A FI783269A (fi) 1979-04-29
FI63674B FI63674B (fi) 1983-04-29
FI63674C true FI63674C (fi) 1983-08-10

Family

ID=27126641

Family Applications (1)

Application Number Title Priority Date Filing Date
FI783269A FI63674C (fi) 1977-10-28 1978-10-26 Foerfarande foer isolering och rening av immunologiskt aktivt polyribosylribitolfosfat (prp)

Country Status (25)

Country Link
JP (1) JPS5480408A (no)
AR (1) AR218932A1 (no)
AU (1) AU520902B2 (no)
BE (1) BE871586A (no)
CA (1) CA1117866A (no)
CH (1) CH649781A5 (no)
DD (1) DD140701A5 (no)
DE (1) DE2845745A1 (no)
DK (1) DK154327C (no)
ES (1) ES474611A1 (no)
FI (1) FI63674C (no)
FR (1) FR2407000B1 (no)
GB (1) GB2007244B (no)
GR (1) GR73991B (no)
HU (1) HU178166B (no)
IE (1) IE47474B1 (no)
IL (1) IL55433A (no)
IT (1) IT1107570B (no)
NL (1) NL7810753A (no)
NO (1) NO149611C (no)
NZ (1) NZ188211A (no)
PH (1) PH15882A (no)
PL (1) PL210545A1 (no)
SE (1) SE430753B (no)
YU (1) YU250878A (no)

Families Citing this family (5)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
BE889979A (fr) * 1981-08-14 1982-02-15 Smith Kline Rit Procede de preparation de polysaccharides bacteriens capsulaires antigeniques purifies, produits obtenus et leur utilisation
CA1209036A (en) * 1982-08-20 1986-08-05 Joseph S.C. Kuo Combined haemophilus influenzae and diphtheria, pertussis, tetanus vaccine
US4744982A (en) * 1982-08-24 1988-05-17 Hunter Kenneth W Human monoclonal antibody reactive with polyribosylribitol phosphate
DE69113564T2 (de) * 1990-08-13 1996-05-30 American Cyanamid Co Faser-Hemagglutinin von Bordetella pertussis als Träger für konjugierten Impfstoff.
WO1993004183A1 (en) * 1991-08-16 1993-03-04 Merck & Co., Inc. Process for converting lipid-containing bacterial capsular polysaccharide into lipid-free polysaccharide

Family Cites Families (8)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US3395219A (en) * 1964-12-11 1968-07-30 Merck & Co Inc Process for production of pertussis antigen
NO116869B (no) * 1965-01-19 1969-06-02 Merck & Co Inc
US3465078A (en) * 1965-10-21 1969-09-02 Sydney Z Spiesel Method of recovering antigens from bordetella pertussis cells
NL174267B (nl) * 1969-05-20 Roussel Uclaf Verbetering van de werkwijze voor de bereiding van een somatisch antigeen volgens het nederlandse octrooischrift 169754 en werkwijze ter bereiding van een farmaceutisch preparaat.
US3636192A (en) * 1970-01-13 1972-01-18 Us Army Meningococcal polysaccharide vaccines
FR2253499B1 (no) * 1973-12-10 1977-11-04 Fabre Sa Pierre
DE2461439C3 (de) * 1974-12-24 1980-03-20 Behringwerke Ag, 3550 Marburg Verfahren zur Herstellung eines schützenden Antigens von Bordetella Pertussis sowie jenes enthaltendes Mittel
US3978209A (en) * 1975-03-24 1976-08-31 Merck & Co., Inc. Endotoxin free meningococcus polysaccharides

Also Published As

Publication number Publication date
DK154327C (da) 1989-04-03
DE2845745C2 (no) 1987-10-01
HU178166B (en) 1982-03-28
BE871586A (fr) 1979-04-27
CH649781A5 (de) 1985-06-14
DE2845745A1 (de) 1979-05-10
NO149611B (no) 1984-02-13
SE430753B (sv) 1983-12-12
SE7811192L (sv) 1979-04-29
GB2007244B (en) 1982-03-31
FI783269A (fi) 1979-04-29
GR73991B (no) 1984-06-06
PL210545A1 (no) 1980-02-25
NZ188211A (en) 1984-09-28
GB2007244A (en) 1979-05-16
YU250878A (en) 1983-12-31
IE782146L (en) 1979-04-28
ES474611A1 (es) 1980-01-16
CA1117866A (en) 1982-02-09
FR2407000B1 (no) 1983-01-21
AR218932A1 (es) 1980-07-15
DD140701A5 (de) 1980-03-26
AU4108178A (en) 1980-05-01
NO149611C (no) 1984-05-23
DK154327B (da) 1988-11-07
FR2407000A1 (no) 1979-05-25
PH15882A (en) 1983-04-13
IT1107570B (it) 1985-11-25
DK479578A (da) 1979-04-29
JPS6231694B2 (no) 1987-07-09
JPS5480408A (en) 1979-06-27
NL7810753A (nl) 1979-05-02
IL55433A0 (en) 1978-10-31
IT7851621A0 (it) 1978-10-24
NO783635L (no) 1979-05-02
IE47474B1 (en) 1984-03-21
FI63674B (fi) 1983-04-29
IL55433A (en) 1982-09-30
AU520902B2 (en) 1982-03-04

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Date Code Title Description
MM Patent lapsed

Owner name: AMERICAN CYANAMID COMPANY