FI60019C - Foerfarande foer framstaellning av antibakteriella 7-((alfa-(2-aminometyl-1-cyklohexenyl- och -1,4-cyklohexadienyl)-acetamido)-3-heterocyklisk-tiometyl-3-cefem-4-karbonsyror - Google Patents

Foerfarande foer framstaellning av antibakteriella 7-((alfa-(2-aminometyl-1-cyklohexenyl- och -1,4-cyklohexadienyl)-acetamido)-3-heterocyklisk-tiometyl-3-cefem-4-karbonsyror Download PDF

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Publication number
FI60019C
FI60019C FI2560/74A FI256074A FI60019C FI 60019 C FI60019 C FI 60019C FI 2560/74 A FI2560/74 A FI 2560/74A FI 256074 A FI256074 A FI 256074A FI 60019 C FI60019 C FI 60019C
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FI
Finland
Prior art keywords
compound
solution
mmol
salt
stirred
Prior art date
Application number
FI2560/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI60019B (fi
FI256074A (ja
Inventor
Takayuki Naito
Hideaki Hoshi
Jun Okumura
Hajime Kamachi
Original Assignee
Bristol Myers Co
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Priority claimed from US394367A external-priority patent/US3907786A/en
Priority claimed from US05/411,559 external-priority patent/US3946000A/en
Application filed by Bristol Myers Co filed Critical Bristol Myers Co
Publication of FI256074A publication Critical patent/FI256074A/fi
Publication of FI60019B publication Critical patent/FI60019B/fi
Application granted granted Critical
Publication of FI60019C publication Critical patent/FI60019C/fi

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    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/121,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04Antibacterial agents
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07CACYCLIC OR CARBOCYCLIC COMPOUNDS
    • C07C271/00Derivatives of carbamic acids, i.e. compounds containing any of the groups, the nitrogen atom not being part of nitro or nitroso groups
    • C07C271/06Esters of carbamic acids
    • C07C271/08Esters of carbamic acids having oxygen atoms of carbamate groups bound to acyclic carbon atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/061,2,3-Thiadiazoles; Hydrogenated 1,2,3-thiadiazoles
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/121,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/1251,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D285/00Heterocyclic compounds containing rings having nitrogen and sulfur atoms as the only ring hetero atoms, not provided for by groups C07D275/00 - C07D283/00
    • C07D285/01Five-membered rings
    • C07D285/02Thiadiazoles; Hydrogenated thiadiazoles
    • C07D285/04Thiadiazoles; Hydrogenated thiadiazoles not condensed with other rings
    • C07D285/121,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles
    • C07D285/1251,3,4-Thiadiazoles; Hydrogenated 1,3,4-thiadiazoles with oxygen, sulfur or nitrogen atoms, directly attached to ring carbon atoms, the nitrogen atoms not forming part of a nitro radical
    • C07D285/135Nitrogen atoms
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D487/00Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00
    • C07D487/02Heterocyclic compounds containing nitrogen atoms as the only ring hetero atoms in the condensed system, not provided for by groups C07D451/00 - C07D477/00 in which the condensed system contains two hetero rings
    • C07D487/04Ortho-condensed systems

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  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Communicable Diseases (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Oncology (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Cephalosporin Compounds (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
FI2560/74A 1973-09-04 1974-09-02 Foerfarande foer framstaellning av antibakteriella 7-((alfa-(2-aminometyl-1-cyklohexenyl- och -1,4-cyklohexadienyl)-acetamido)-3-heterocyklisk-tiometyl-3-cefem-4-karbonsyror FI60019C (fi)

Applications Claiming Priority (4)

Application Number Priority Date Filing Date Title
US394367A US3907786A (en) 1973-09-04 1973-09-04 7-{8 {60 -(2-aminomethyl-1,4-cyclohexadienyl)acetamido{9 -3-heterocyclic-thiomethyl-3-cephem-4-carboxylic acids and salts
US39436773 1973-09-04
US05/411,559 US3946000A (en) 1973-10-31 1973-10-31 7-[α-(2-Aminomethyl-1-cyclohexenyl)-acetamido]-3-heterocyclic thiomethyl-3-cephem-4-carboxylic acids
US41155973 1973-10-31

Publications (3)

Publication Number Publication Date
FI256074A FI256074A (ja) 1975-03-05
FI60019B FI60019B (fi) 1981-07-31
FI60019C true FI60019C (fi) 1981-11-10

Family

ID=27014711

Family Applications (1)

Application Number Title Priority Date Filing Date
FI2560/74A FI60019C (fi) 1973-09-04 1974-09-02 Foerfarande foer framstaellning av antibakteriella 7-((alfa-(2-aminometyl-1-cyklohexenyl- och -1,4-cyklohexadienyl)-acetamido)-3-heterocyklisk-tiometyl-3-cefem-4-karbonsyror

Country Status (13)

Country Link
JP (1) JPS5924158B2 (ja)
CA (1) CA1037467A (ja)
CH (1) CH613458A5 (ja)
DE (1) DE2442302C2 (ja)
DK (1) DK143941C (ja)
FI (1) FI60019C (ja)
FR (1) FR2242103B1 (ja)
GB (1) GB1474790A (ja)
HU (1) HU169170B (ja)
IE (1) IE39830B1 (ja)
NL (1) NL7411569A (ja)
SE (1) SE423714B (ja)
YU (1) YU233874A (ja)

Families Citing this family (2)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
JP2004538265A (ja) * 2001-04-19 2004-12-24 ビオフェルマ ムルシア,エス.アー. α−ケト酸誘導体を使用して3−セファロスポラン酸誘導体を製造する方法
CN112645883B (zh) * 2020-12-23 2022-10-25 天和药业股份有限公司 一种3,6-二氯哒嗪的制备方法

Also Published As

Publication number Publication date
DE2442302C2 (de) 1982-11-18
IE39830L (en) 1975-03-04
FI60019B (fi) 1981-07-31
CA1037467A (en) 1978-08-29
GB1474790A (en) 1977-05-25
DK143941B (da) 1981-11-02
YU233874A (en) 1982-06-30
SE7411146L (ja) 1975-03-05
DE2442302A1 (de) 1975-03-06
SE423714B (sv) 1982-05-24
FI256074A (ja) 1975-03-05
JPS5924158B2 (ja) 1984-06-07
JPS5058089A (ja) 1975-05-20
FR2242103A1 (ja) 1975-03-28
DK466574A (ja) 1975-05-05
CH613458A5 (en) 1979-09-28
NL7411569A (nl) 1975-03-06
DK143941C (da) 1982-04-13
HU169170B (ja) 1976-10-28
IE39830B1 (en) 1979-01-03
AU7291474A (en) 1976-03-11
FR2242103B1 (ja) 1978-07-21

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