FI59254C - Foerfarande foer framstaellning av nya terapeutiskt anvaendbara ergopeptinderivat - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt anvaendbara ergopeptinderivat Download PDF

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Publication number
FI59254C
FI59254C FI3345/74A FI334574A FI59254C FI 59254 C FI59254 C FI 59254C FI 3345/74 A FI3345/74 A FI 3345/74A FI 334574 A FI334574 A FI 334574A FI 59254 C FI59254 C FI 59254C
Authority
FI
Finland
Prior art keywords
formula
compounds
acid
preparation
framework
Prior art date
Application number
FI3345/74A
Other languages
English (en)
Finnish (fi)
Other versions
FI334574A (US06826419-20041130-M00005.png
FI59254B (fi
Inventor
Theodor Fehr
Paul Stadler
Original Assignee
Sandoz Ag
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Sandoz Ag filed Critical Sandoz Ag
Publication of FI334574A publication Critical patent/FI334574A/fi
Publication of FI59254B publication Critical patent/FI59254B/fi
Application granted granted Critical
Publication of FI59254C publication Critical patent/FI59254C/fi

Links

Classifications

    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D457/00Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid
    • C07D457/04Heterocyclic compounds containing indolo [4, 3-f, g] quinoline ring systems, e.g. derivatives of ergoline, of the formula:, e.g. lysergic acid with carbon atoms having three bonds to hetero atoms with at the most one bond to halogen, e.g. ester or nitrile radicals, directly attached in position 8
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • AHUMAN NECESSITIES
    • A61MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61PSPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P9/00Drugs for disorders of the cardiovascular system
    • A61P9/02Non-specific cardiovascular stimulants, e.g. drugs for syncope, antihypotensives
    • CCHEMISTRY; METALLURGY
    • C07ORGANIC CHEMISTRY
    • C07DHETEROCYCLIC COMPOUNDS
    • C07D519/00Heterocyclic compounds containing more than one system of two or more relevant hetero rings condensed among themselves or condensed with a common carbocyclic ring system not provided for in groups C07D453/00 or C07D455/00
    • C07D519/02Ergot alkaloids of the cyclic peptide type

Landscapes

  • Organic Chemistry (AREA)
  • Chemical & Material Sciences (AREA)
  • Health & Medical Sciences (AREA)
  • Bioinformatics & Cheminformatics (AREA)
  • Cardiology (AREA)
  • Heart & Thoracic Surgery (AREA)
  • Engineering & Computer Science (AREA)
  • Veterinary Medicine (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • General Chemical & Material Sciences (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • Medicinal Chemistry (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
  • Peptides Or Proteins (AREA)
  • Organic Low-Molecular-Weight Compounds And Preparation Thereof (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Nitrogen Condensed Heterocyclic Rings (AREA)
  • Pyridine Compounds (AREA)
FI3345/74A 1973-11-28 1974-11-19 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara ergopeptinderivat FI59254C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
CH1669873 1973-11-28
CH1669873A CH587858A5 (US06826419-20041130-M00005.png) 1973-11-28 1973-11-28

Publications (3)

Publication Number Publication Date
FI334574A FI334574A (US06826419-20041130-M00005.png) 1975-05-29
FI59254B FI59254B (fi) 1981-03-31
FI59254C true FI59254C (fi) 1981-07-10

Family

ID=4419482

Family Applications (1)

Application Number Title Priority Date Filing Date
FI3345/74A FI59254C (fi) 1973-11-28 1974-11-19 Foerfarande foer framstaellning av nya terapeutiskt anvaendbara ergopeptinderivat

Country Status (25)

Country Link
US (1) US4229451A (US06826419-20041130-M00005.png)
JP (1) JPS5919116B2 (US06826419-20041130-M00005.png)
AT (1) AT352911B (US06826419-20041130-M00005.png)
BE (1) BE822729A (US06826419-20041130-M00005.png)
CA (1) CA1034572A (US06826419-20041130-M00005.png)
CH (1) CH587858A5 (US06826419-20041130-M00005.png)
CS (1) CS176291B2 (US06826419-20041130-M00005.png)
DD (1) DD115119A5 (US06826419-20041130-M00005.png)
DE (1) DE2454619A1 (US06826419-20041130-M00005.png)
DK (1) DK143804C (US06826419-20041130-M00005.png)
ES (1) ES432288A1 (US06826419-20041130-M00005.png)
FI (1) FI59254C (US06826419-20041130-M00005.png)
FR (2) FR2252098B1 (US06826419-20041130-M00005.png)
GB (2) GB1496491A (US06826419-20041130-M00005.png)
HK (1) HK54080A (US06826419-20041130-M00005.png)
HU (1) HU168859B (US06826419-20041130-M00005.png)
IE (1) IE41767B1 (US06826419-20041130-M00005.png)
IL (1) IL46128A (US06826419-20041130-M00005.png)
MY (1) MY8100185A (US06826419-20041130-M00005.png)
NL (1) NL7415250A (US06826419-20041130-M00005.png)
NO (1) NO744175L (US06826419-20041130-M00005.png)
PH (1) PH13669A (US06826419-20041130-M00005.png)
SE (2) SE417319B (US06826419-20041130-M00005.png)
SU (1) SU516355A3 (US06826419-20041130-M00005.png)
ZA (1) ZA747603B (US06826419-20041130-M00005.png)

Families Citing this family (9)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
CH601321A5 (US06826419-20041130-M00005.png) * 1975-01-06 1978-07-14 Sandoz Ag
CH619468A5 (US06826419-20041130-M00005.png) * 1976-01-12 1980-09-30 Sandoz Ag
DE3020895A1 (de) * 1979-06-12 1980-12-18 Sandoz Ag Ergopeptinderivate, verfahren zu deren herstellung sowie diese ergopeptinderivate enthaltende pharmazeutischen zusammensetzungen
US5069911A (en) * 1985-02-05 1991-12-03 Sandoz Ltd. Pharmaceutical 9,10-dihydrogenated ergot alkaloid containing compositions
US7771746B2 (en) * 1999-12-03 2010-08-10 Polichem Sa Methods for making sustained-release pharmaceutical compositions of ergot alkaloids having improved bioavailability and compositions thereof
GB0409785D0 (en) * 2004-04-30 2004-06-09 Resolution Chemicals Ltd Preparation of cabergoline
GB0505965D0 (en) * 2005-03-23 2005-04-27 Resolution Chemicals Ltd Preparation of cabergoline
US7339060B2 (en) 2005-03-23 2008-03-04 Resolution Chemicals, Ltd. Preparation of cabergoline
US20070197576A1 (en) * 2006-02-08 2007-08-23 Resolution Chemicals Limited Production of Cabergoline and Novel Polymorphic Form Thereof

Family Cites Families (10)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
US2619488A (en) * 1952-11-25 Method of preparing d
DE1006425B (de) * 1954-04-07 1957-04-18 Sandoz Ag Verfahren zur Herstellung der isomeren racemischen Dihydrolysergsaeuren und ihren Homologen
GB769260A (en) * 1954-04-07 1957-03-06 Sandoz Ltd Process for the preparation of isomeric racemic dihydrolysergic acids and their homologues
GB1011112A (en) * 1961-05-10 1965-11-24 Sandoz Ag Improvements in or relating to ergot alkaloids
CH469006A (de) * 1965-07-07 1969-02-28 Sandoz Ag Verfahren zur Herstellung neuer synthetischer Alkaloide
CH469735A (de) * 1965-11-02 1969-03-15 Sandoz Ag Verfahren zur Herstellung heterocyclischer Verbindungen
GB1298277A (en) * 1969-04-18 1972-11-29 Sandoz Ltd Preparation of ergot peptide alkaloids
CH534683A (de) * 1970-05-26 1973-03-15 Sandoz Ag Verfahren zur Herstellung neuer Mutterkornpeptidalkaloide
CH601321A5 (US06826419-20041130-M00005.png) * 1975-01-06 1978-07-14 Sandoz Ag
US4138565A (en) * 1975-05-31 1979-02-06 Sandoz Ltd. Stable solutions and processes for their preparation

Also Published As

Publication number Publication date
NO744175L (US06826419-20041130-M00005.png) 1975-06-23
DE2454619A1 (de) 1975-06-05
NL7415250A (nl) 1975-05-30
HU168859B (US06826419-20041130-M00005.png) 1976-07-28
FR2252098B1 (US06826419-20041130-M00005.png) 1978-06-30
IL46128A0 (en) 1975-02-10
US4229451A (en) 1980-10-21
DD115119A5 (US06826419-20041130-M00005.png) 1975-09-12
AU7582674A (en) 1976-05-27
SE424869B (sv) 1982-08-16
CS176291B2 (US06826419-20041130-M00005.png) 1977-06-30
SE7710418L (sv) 1977-09-16
MY8100185A (en) 1981-12-31
CH587858A5 (US06826419-20041130-M00005.png) 1977-05-13
BE822729A (fr) 1975-05-28
FI334574A (US06826419-20041130-M00005.png) 1975-05-29
SE417319B (sv) 1981-03-09
GB1496491A (en) 1977-12-30
DK600374A (US06826419-20041130-M00005.png) 1975-07-28
IE41767L (en) 1975-05-28
IL46128A (en) 1977-10-31
DK143804C (da) 1982-03-29
GB1496492A (en) 1977-12-30
DK143804B (da) 1981-10-12
JPS5084599A (US06826419-20041130-M00005.png) 1975-07-08
FR2252098A1 (US06826419-20041130-M00005.png) 1975-06-20
FR2334681A1 (fr) 1977-07-08
FI59254B (fi) 1981-03-31
ZA747603B (en) 1976-07-28
AT352911B (de) 1979-10-10
ES432288A1 (es) 1977-02-16
FR2334681B1 (US06826419-20041130-M00005.png) 1980-04-18
SU516355A3 (ru) 1976-05-30
JPS5919116B2 (ja) 1984-05-02
CA1034572A (en) 1978-07-11
HK54080A (en) 1980-10-03
PH13669A (en) 1980-08-26
SE7414607L (US06826419-20041130-M00005.png) 1975-05-29
IE41767B1 (en) 1980-03-26
ATA945174A (de) 1979-03-15

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