FI59102C - Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar - Google Patents

Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar Download PDF

Info

Publication number
FI59102C
FI59102C FI760561A FI760561A FI59102C FI 59102 C FI59102 C FI 59102C FI 760561 A FI760561 A FI 760561A FI 760561 A FI760561 A FI 760561A FI 59102 C FI59102 C FI 59102C
Authority
FI
Finland
Prior art keywords
cyclopentyl
rifampicin
derivative
effective
compound
Prior art date
Application number
FI760561A
Other languages
English (en)
Finnish (fi)
Other versions
FI59102B (fi
FI760561A (de
Inventor
Renato Cricchio
Vittorio Arioli
Original Assignee
Lepetit Spa
Priority date (The priority date is an assumption and is not a legal conclusion. Google has not performed a legal analysis and makes no representation as to the accuracy of the date listed.)
Filing date
Publication date
Application filed by Lepetit Spa filed Critical Lepetit Spa
Publication of FI760561A publication Critical patent/FI760561A/fi
Publication of FI59102B publication Critical patent/FI59102B/fi
Application granted granted Critical
Publication of FI59102C publication Critical patent/FI59102C/fi

Links

Classifications

    • C—CHEMISTRY; METALLURGY
    • C07—ORGANIC CHEMISTRY
    • C07D—HETEROCYCLIC COMPOUNDS
    • C07D498/00—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms
    • C07D498/02—Heterocyclic compounds containing in the condensed system at least one hetero ring having nitrogen and oxygen atoms as the only ring hetero atoms in which the condensed system contains two hetero rings
    • C07D498/08—Bridged systems
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A—HUMAN NECESSITIES
    • A61—MEDICAL OR VETERINARY SCIENCE; HYGIENE
    • A61P—SPECIFIC THERAPEUTIC ACTIVITY OF CHEMICAL COMPOUNDS OR MEDICINAL PREPARATIONS
    • A61P31/00—Antiinfectives, i.e. antibiotics, antiseptics, chemotherapeutics
    • A61P31/04—Antibacterial agents

Landscapes

  • Chemical & Material Sciences (AREA)
  • Organic Chemistry (AREA)
  • Health & Medical Sciences (AREA)
  • Communicable Diseases (AREA)
  • Oncology (AREA)
  • Chemical Kinetics & Catalysis (AREA)
  • General Chemical & Material Sciences (AREA)
  • Medicinal Chemistry (AREA)
  • Nuclear Medicine, Radiotherapy & Molecular Imaging (AREA)
  • Pharmacology & Pharmacy (AREA)
  • Life Sciences & Earth Sciences (AREA)
  • Animal Behavior & Ethology (AREA)
  • General Health & Medical Sciences (AREA)
  • Public Health (AREA)
  • Veterinary Medicine (AREA)
  • Nitrogen And Oxygen Or Sulfur-Condensed Heterocyclic Ring Systems (AREA)
  • Pharmaceuticals Containing Other Organic And Inorganic Compounds (AREA)
FI760561A 1975-03-05 1976-03-05 Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar FI59102C (fi)

Applications Claiming Priority (2)

Application Number Priority Date Filing Date Title
GB10020/75A GB1478563A (en) 1975-03-05 1975-03-05 Rifamycin derivatives
GB1002075 1975-03-05

Publications (3)

Publication Number Publication Date
FI760561A FI760561A (de) 1976-09-06
FI59102B FI59102B (fi) 1981-02-27
FI59102C true FI59102C (fi) 1981-06-10

Family

ID=9959968

Family Applications (1)

Application Number Title Priority Date Filing Date
FI760561A FI59102C (fi) 1975-03-05 1976-03-05 Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar

Country Status (27)

Country Link
US (1) US4002752A (de)
JP (1) JPS51113900A (de)
AR (1) AR210113A1 (de)
AT (1) AT344896B (de)
BE (1) BE839255A (de)
CA (1) CA1057748A (de)
CH (1) CH610325A5 (de)
DD (1) DD123888A5 (de)
DE (1) DE2608218C3 (de)
DK (1) DK136655B (de)
ES (1) ES445790A1 (de)
FI (1) FI59102C (de)
FR (1) FR2302742A1 (de)
GB (1) GB1478563A (de)
HK (1) HK35282A (de)
HU (1) HU170451B (de)
IE (1) IE42881B1 (de)
KE (1) KE3099A (de)
LU (1) LU74478A1 (de)
MX (1) MX3737E (de)
NL (1) NL165745C (de)
NO (1) NO143796C (de)
PT (1) PT64866B (de)
SE (1) SE420728B (de)
SU (1) SU575030A3 (de)
YU (1) YU39477B (de)
ZA (1) ZA761043B (de)

Families Citing this family (18)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
DE2728869A1 (de) * 1976-06-25 1977-12-29 Antibiotice Iasi Intreprindere Rifamycinen und verfahren zu deren herstellung
GR64108B (en) * 1977-04-15 1980-01-24 Dso Pharmachim Method for the preparation of azomethine-derivatives of rifamycin s.v
GB1576886A (en) * 1977-04-20 1980-10-15 Lepetit Spa Rifamycin derivatives
GB1594134A (en) * 1977-11-25 1981-07-30 Holco Investment Inc Rifamycins
AU536524B2 (en) * 1979-06-28 1984-05-10 Gruppo Lepetit S.P.A. Water soluble hydrozones of 3-formylifamyan
US4447432A (en) * 1981-11-17 1984-05-08 Farmitalia Carlo Erba S.P.A. Azino rifamycins
US4681938A (en) * 1984-08-27 1987-07-21 Ciba-Geigy Corporation Novel polycyclic hydrazones of rifamycins, their manufacture, and their pharmaceutical compositions for treating tuberculosis
WO1987002361A1 (en) * 1985-10-18 1987-04-23 Ciba-Geigy Ag Substituted 4-benzyl-piperazinyl compounds
US4916126A (en) * 1987-09-25 1990-04-10 Ciba-Geigy Corporation Diacyl derivatives of 4-(trialkylbenzyl)-piperazinyl compounds
GB8816620D0 (en) * 1988-07-13 1988-08-17 Lepetit Spa Rifapentine hydrohalides
JP3350861B2 (ja) * 1990-06-29 2002-11-25 アベンテイス・バルク・ソチエタ・ペル・アチオニ リファペンチンの純粋の結晶型
BRPI0614758A2 (pt) 2005-08-11 2011-04-12 Targanta Therapeutics Inc rifamicinas fosfonadas e usos destas para a prevenção e tratamento de infecções na articulação e osso
US8524691B2 (en) 2008-08-13 2013-09-03 The Medicines Company Phosphonated rifamycins and uses thereof for the prevention and treatment of bone and joint infections
RU2496475C2 (ru) 2011-10-26 2013-10-27 Александр Васильевич Иващенко Фармацевтическая композиция и набор для лечения бактериальных инфекций
KR102210848B1 (ko) 2012-08-13 2021-02-02 아디팜 에아드 3-포르밀리파마이신 sv 및 3-포르밀리파마이신 s의 3-(4-신나밀-1-피페라지닐) 아미노 유도체를 함유하는 제약 제제 및 그의 제조 방법
CN103951677B (zh) * 2014-03-17 2016-04-06 四川省长征药业股份有限公司 利福喷丁的制备方法
MX2023012416A (es) * 2021-04-21 2024-03-05 Interquim S A De C V Proceso de obtencion de rifapentina con una nueva forma cristalina.
CN115047122B (zh) * 2022-06-29 2023-05-02 重庆华邦胜凯制药有限公司 利福喷丁及其合成过程中所产生的杂质的分析方法

Family Cites Families (3)

* Cited by examiner, † Cited by third party
Publication number Priority date Publication date Assignee Title
FR208F (de) * 1964-07-31
AR205434A1 (es) * 1972-03-27 1976-05-07 Lepetit Spa Proceso para la preparacion de 3-acilhidrazonometil rifamicinas sv
GB1392272A (en) * 1972-05-31 1975-04-30 Lepetit Spa 3-formylrifamycin azines

Also Published As

Publication number Publication date
YU39477B (en) 1984-12-31
NO143796C (no) 1981-04-15
DK78476A (de) 1976-09-06
HU170451B (de) 1977-06-28
KE3099A (en) 1981-02-13
DE2608218A1 (de) 1976-09-16
FI59102B (fi) 1981-02-27
ES445790A1 (es) 1977-06-01
NL165745B (nl) 1980-12-15
YU57276A (en) 1982-06-30
NO760549L (de) 1976-09-07
FI760561A (de) 1976-09-06
NL7602191A (nl) 1976-09-07
SU575030A3 (ru) 1977-09-30
DK136655C (de) 1978-04-17
DE2608218C3 (de) 1981-12-10
LU74478A1 (de) 1976-09-01
AT344896B (de) 1978-08-10
SE420728B (sv) 1981-10-26
BE839255A (fr) 1976-09-06
HK35282A (en) 1982-08-13
NO143796B (no) 1981-01-05
SE7602122L (sv) 1976-09-06
ATA162876A (de) 1977-12-15
PT64866A (en) 1976-04-01
CH610325A5 (de) 1979-04-12
NL165745C (nl) 1981-05-15
AU1170476A (en) 1977-09-08
DD123888A5 (de) 1977-01-19
IE42881L (en) 1976-09-05
US4002752A (en) 1977-01-11
PT64866B (en) 1977-07-20
IE42881B1 (en) 1980-11-05
FR2302742B1 (de) 1979-10-12
DK136655B (da) 1977-11-07
DE2608218B2 (de) 1981-02-26
AR210113A1 (es) 1977-06-30
MX3737E (es) 1981-06-05
JPS5530797B2 (de) 1980-08-13
JPS51113900A (en) 1976-10-07
CA1057748A (en) 1979-07-03
ZA761043B (en) 1977-01-26
FR2302742A1 (fr) 1976-10-01
GB1478563A (en) 1977-07-06

Similar Documents

Publication Publication Date Title
FI59102C (fi) Foerfarande foer framstaellning av nya terapeutiskt effektiva piperazinyliminorifamycinfoereningar
US4983602A (en) 3'-hydroxybenzoxazinorifamycin derivative, process for preparing the same and antibacterial agent containing the same
CA1135262A (en) Maytansinoids, their production and use
Diana et al. [[(4, 5-Dihydro-2-oxazolyl) phenoxy] alkyl] isoxazoles. Inhibitors of picornavirus uncoating
US4268676A (en) Mitomycin analogs
CA2739503A1 (fr) Nouveaux composes heterocycliques azotes, leur preparation et leur utilisation comme medicaments antibacteriens
FR2720396A1 (fr) Nouveaux N-pyridyl carboxamides et dérivés leur procédé de préparation et les compositions pharmaceutiques qui les contiennent.
El Shehry et al. Design, synthesis and biological evaluation of quinoxaline N-propionic and O-propionic hydrazide derivatives as antibacterial and antifungal agents
US4075339A (en) Biologically active compounds
FI87567B (fi) Foerfarande foer framstaellning av terapeutiskt verkande 8-o,n- och 8-o,21-diacyl-4-(trialkylbensyl)-piperazin-1-ylderivat av rifamycin s
FR2501204A1 (fr) Derives d'un acide quinoleine-carboxylique, procede pour les preparer et medicament en contenant
NL8301949A (nl) Amidines en werkwijze voor het bereiden daarvan.
US4965261A (en) Substituted benzoxazinorifamycin derivative and antibacterial agent containing the same
FI62074C (fi) Foerfarande foer framstaellning av nya farmakologiskt aktiva 5-fenyl-oxazolidinon-2-foereningar
US4002754A (en) Substituted piperazinyliminorifamycins
CA1244412A (en) Mitomycin analogs
FI78069B (fi) Foerfarande foer framstaellning av saosom laekemedel anvaendbara acylerade enamidfoereningar.
US4460599A (en) Mitomycin analogs
FI69058B (fi) Foerfarande foer framstaellning av terapeutiskt anvaendbara bi(nitrosoureido)polyolderivat
NISHII et al. A new antitumor antibiotic, guanine 7-N-oxide produced by Streptomyces sp
Uno et al. Synthesis of antimicrobial agents. 3. Syntheses and antibacterial activities of 7-(4-hydroxypiperazin-1-yl) quinolones
OKUDA et al. Penitricin, a new class of antibiotic produced by Penicillium aculeatum III. Structural confirmation by chemical synthesis and biological activity
US4748251A (en) 7-n-aminomethylenemitomycin derivative
Rinehart Jr et al. Synthesis of hydrazones and oximes of geldanaldehyde as potential polymerase inhibitors
SU1258327A3 (ru) Способ получени 7-замещенных 9 @ -метоксимитозана

Legal Events

Date Code Title Description
MA Patent expired
MA Patent expired

Owner name: GRUPPO LEPETIT S.P.A